scholarly journals Association between rotavirus gastroenteritis and intussusception: suggested evidence from a retrospective study in claims databases in the United States. Corresponding author: Corinne Willame, MPH, GSK, 20 Avenue Fleming, Wavre, Belgium

2019 ◽  
Author(s):  
Corinne Willame ◽  
Brigitte Cheuvart ◽  
Emmanuel Aris ◽  
Volker Vetter ◽  
Catherine Cohet
Keyword(s):  
United States ◽  
Sensitivity Analysis ◽  
Case Series ◽  
The United States ◽  
Temporal Association ◽  
Administrative Claims ◽  
Fracture Group ◽  
Rotavirus Gastroenteritis ◽  
Risk Period ◽  
Post Hoc

Abstract Background: The etiology of intussusception (IS), a serious medical condition of acute gastrointestinal obstruction, remains unclear. Limited evidence suggests a role for viral infections, including rotavirus infection. This study aimed to explore the risk of IS after rotavirus gastroenteritis (RV GE) in the first year of life, where the incidence of IS is highest. Methods: In this retrospective, self-controlled case series (SCCS), we assessed the risk of IS after RV GE in infants <1 year of age, using data extracted from administrative claims databases in the United States. Incidence rate ratios (IRR) of IS were calculated for the 7- and 21-day risk periods after RV GE (main analysis) or after fracture (sensitivity analysis using a control event) in subjects presenting with claims for these conditions. Post-hoc analyses were also performed. Results: Out of the 290,912,068 subjects screened, 42 subjects presented claims for RV GE and IS (RV GE group) and 66 presented claims for fracture and IS (fracture group). The IRR of IS after RV GE was 79.6 (95% confidence interval, CI: 38.6–164.4) in the 7-day risk period and 25.5 (95% CI: 13.2–49.2) in the 21-day risk period. The sensitivity analysis also showed an association between IS and fracture for the two risk periods: IRR was 6.1 (95% CI: 3.0–12.7) and 2.8 (95% CI: 1.5–5.4) in the 7- and 21-day risk periods, respectively, which suggested potential confounding such as by history of rotavirus vaccination, or a visit effect. Post-hoc analyses investigating these points did not confirm an association between fracture and IS, but still suggested a possible association between RV GE and IS. Conclusions: A temporal association between RV GE and IS was detected using the SCCS design in United States claims databases. However, due to some limitations identified through additional analyses, further studies are needed to confirm this association.

Clinical Characteristics of Patients Diagnosed with Strongyloidiasis in a United States Urban Outpatient Dermatology Department: A Case Series

2017 ◽  
Vol 1 (3) ◽  
pp. 156-160
Author(s):  
Jacqueline Watchmaker ◽  
Sean Legler ◽  
Dianne De Leon ◽  
Vanessa Pascoe ◽  
Robert Stavert
Keyword(s):  
United States ◽  
Case Series ◽  
The United States ◽  
Screening Tools ◽  
Dermatology Department ◽  
Cutaneous Manifestations ◽  
Serologic Testing ◽  
Patient Reported ◽  
History Of ◽  
Endemic Areas

Background: Although considered a tropical disease, strongyloidiasis may be encountered in non-endemic regions, primarily amongst immigrants and travelers from endemic areas.  Chronic strongyloides infection may be under-detected owing to its non-specific cutaneous presentation and the low sensitivity of commonly used screening tools. Methods: 18 consecutive patients with serologic evidence of strongyloides infestation who presented to a single urban, academic dermatology clinic between September 2013 and October 2016 were retrospectively included.  Patient age, sex, country of origin, strongyloides serology titer, absolute eosinophil count, presenting cutaneous manifestations, and patient reported subjective outcome of pruritus after treatment were obtained via chart review.  Results: Of the 18 patients, all had non-specific pruritic dermatoses, 36% had documented eosinophila and none were originally from the United States. A majority reported subjective improvement in their symptoms after treatment. Conclusion:  Strongyloides infection and serologic testing should be considered in patients living in non-endemic regions presenting with pruritic dermatoses and with a history of exposure to an endemic area.Key Points:Chronic strongyloidiasis can be encountered in non-endemic areas and clinical manifestations are variableEosinophilia was not a reliable indicator of chronic infection in this case series Dermatologists should consider serologic testing for strongyloidiasis in patients with a history of exposure and unexplained pruritus

scholarly journals Neurofibromatosis type 1 and chronic neurological conditions in the United States: an administrative claims analysis

2014 ◽  
Vol 17 (1) ◽  
pp. 36-42 ◽  
Author(s):  
Chinwe C. Madubata ◽  
Margaret A. Olsen ◽  
Dustin L. Stwalley ◽  
David H. Gutmann ◽  
Kimberly J. Johnson
Keyword(s):  
United States ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
The United States ◽  
Administrative Claims ◽  
Claims Analysis ◽  
Neurological Conditions

scholarly journals Notational analysis in female grand slam tennis competitions

Kinesiology ◽  
2021 ◽  
Vol 53 (1) ◽  
pp. 154-161
Author(s):  
Alejandro Sánchez-Pay ◽  
José Antonio Ortega-Soto ◽  
Bernardino J. Sánchez-Alcaraz
Keyword(s):  
United States ◽  
Analysis Of Variance ◽  
The United States ◽  
Wilcoxon Test ◽  
Specific Training ◽  
Improve Performance ◽  
Test Analysis ◽  
Notational Analysis ◽  
Break Points ◽  
Post Hoc

Grand Slam tennis tournaments are played on different surfaces. The aims of the present study were to analyse the technical differences in the Grand Slam tournaments (Australian Open or AO, Roland Garros or RG, Wimbledon or W, and the United States Open or US), as well as to establish differences between winning and losing players. A total of 580 sets in 248 matches played in Grand Slams between 2017 and 2018 were analysed. To observe differences between the tournaments, a one-way analysis of variance (Kruskal Wallis) with the Bonferroni post-hoc test was performed. Univariate (Wilcoxon test) analysis of data was carried out to show the differences between the winning and losing performances of sets. Players who had more aces, points won on the 1st serve, winning shots and net points won more matches in the AO, W and US than in the RG (p&lt;.05). However, in RG, players won more receiving points (43.56% of the points played) with chances to break the opponents’ service game. The results also showed that the winning players were superior in both service and receiving, and the most influential variables on the outcome of the match were percentage of receiving points won, break points won, and percentage of points won on the first serve. Such knowledge may have implications in the design of appropriate game strategies and specific training sessions to improve performance in professional women’s tennis.

scholarly journals A Case Series: Describing the Coronavirus Pandemic Response in Small Naval OCONUS Military Treatment Facilities

2021 ◽  
Vol 186 (Supplement_2) ◽  
pp. 61-67
Author(s):  
Emily R Latimer ◽  
Christopher A Parker ◽  
Pauline A Swiger
Keyword(s):  
United States ◽  
Case Series ◽  
The United States ◽  
Staff Protection ◽  
Treatment Facilities ◽  
Pandemic Response ◽  
Future Work ◽  
Military Treatment Facilities ◽  
Communication Methods ◽  
Prolonged Stress

ABSTRACT Introduction The European SARS-CoV-2 (COVID-19) outbreak threatened military beneficiaries receiving care outside of the United States. Military treatment facilities located outside the United States were the first to respond to the pandemic, requiring immediate action to establish novel protocols. The purpose of this case series is to describe challenges, solutions, and future recommendations during a pandemic response at three small naval military treatment facilities located outside the continental United States (OCONUS). Results The analysis and discussion reviews challenges in information processing, communication methods and patterns, process changes, actions for staff protection, and change fatigue experienced during this time. Conclusions Recommendations for future work include filling the gaps in the evidence for a prolonged pandemic response and crisis management, such as the current SARS-CoV-2 pandemic, including best practices to communicate, maintain staff resilience, and manage or mitigate associated prolonged stress and uncertainty.

Active, Population-Based Surveillance for Severe Rotavirus Gastroenteritis in Children in the United States

PEDIATRICS ◽  
2008 ◽  
Vol 122 (6) ◽  
pp. 1235-1243 ◽  
Author(s):  
D. C. Payne ◽  
M. A. Staat ◽  
K. M. Edwards ◽  
P. G. Szilagyi ◽  
J. R. Gentsch ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Population Based ◽  
Rotavirus Gastroenteritis ◽  
Active Population

The prevalence of localised scleroderma in childhood assessed in the administrative claims data from the United States

2018 ◽  
Vol 4 (1) ◽  
pp. 77-78
Author(s):  
Timothy Beukelman ◽  
Fenglong Xie ◽  
Ivan Foeldvari
Keyword(s):  
United States ◽  
Systemic Sclerosis ◽  
Claims Data ◽  
International Classification Of Diseases ◽  
The United States ◽  
Administrative Claims ◽  
Administrative Claims Data ◽  
Diagnosis Codes ◽  
Classification Of Diseases

Juvenile localised scleroderma is believed an orphan autoimmune disease, which occurs 10 times more often than systemic sclerosis in childhood and is believed to have a prevalence of 1 per 100,000 children. To gain data regarding the prevalence of juvenile localised scleroderma, we assessed the administrative claims data in the United States using the International Classification of Diseases, Ninth Revision diagnosis codes. We found an estimated prevalence in each year ranging from 3.2 to 3.6 per 10,000 children. This estimate is significantly higher as found in previous studies.

scholarly journals Higher Psoriasis Skin Clearance Is Associated with Lower Annual Indirect Costs in the United States: A Post Hoc Analysis from the CLEAR Study

2018 ◽  
Vol 24 (7) ◽  
pp. 617-622 ◽  
Author(s):  
Steven R. Feldman ◽  
Yang Zhao ◽  
Isabelle Gilloteau ◽  
Christopher N. Graham ◽  
LaStella Miles ◽  
...  
Keyword(s):  
United States ◽  
Indirect Costs ◽  
The United States ◽  
Post Hoc Analysis ◽  
Post Hoc
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