scholarly journals Theme trends in research related to retinal vein occlusion: a quantitative and co-word analysis

2019 ◽  
Author(s):  
Fei Liu ◽  
Ximei Chen ◽  
Miao Zhao

Abstract Background. This study focused on plotting knowledge structure and exploring research hotspots of retinal vein occlusion (RVO). Methods. In this study, research articles, with subject of RVO, were acquired from PubMed. Bibliographic Item Co-Occurrence Matrix Builder (BICOMB) was used for MeSH terms acquisition, evaluation and high-frequency MeSH term determination. Biclustering analysis and knowledge structure were conducted based on the MeSH term-source article matrix. RVO theme trends were illustrated with social network analysis (SNA), along with strategic diagrams. Results. A total of 3179 articles on RVO were retrieved, and the annual research output increased with time. USA ranked first with the most publications, with Retina as the most prolific journal in RVO research. MeSH terms were characterized into five different genres. As shown by the strategic diagram, the complications of RVO, the etiology of macular edema, as well as the therapeutic use of anti-VEGF, steroids and anti-inflammatory agents were well developed (Quadrant I). In contrast, epidemiology, metabolism and genetics related research on RVO were relatively immature (Quadrant III). Research on surgical treatments of vitrectomy, diagnostic methods and pathology of RVO were centralized but undeveloped (Quadrant IV). The SNA results was exhibited by the centrality chart, on which the node position was represented by the centrality values. Conclusions. By providing a bibliometric research, the overall RVO research trends could be revealed based on the five categories identified by this study. The mathematical bibliometric study could shed light on new perspectives for researchers.

Author(s):  
M.S. Krivosheeva ◽  
◽  
E.E. Ioyleva ◽  

A clinical case of observation of a patient who had branch retinal vein occlusion with the development of macular edema, against the background of a moderate-severe course of COVID-19, was considered. The clinical picture and diagnostic methods necessary for the diagnosis are described. Some aspects of pathological changes in the organ of sight in COVID-19 are discussed. Key words: COVID-19, branch retinal vein occlusion, macular edema, renin-angiotensin-aldosterone system.


2003 ◽  
Vol 18 (3) ◽  
pp. 142-146 ◽  
Author(s):  
Maurizio Battaglia Parodi ◽  
Paolo Lanzetta ◽  
Giuseppe Guarnaccia ◽  
Thomas Friberg

2016 ◽  
Vol 10 (01) ◽  
pp. 25 ◽  
Author(s):  
Stephan Michels ◽  
Magdalena Anna Wirth ◽  
◽  
◽  

The advent of new pharmacotherapeutic options and diagnostic methods have led to a revolution in the management of branch retinal vein occlusion over the past few years. Despite the variety of treatment options, we are confronted with several questions: which drug should we use? Is switching between or combining treatment options beneficial? What is the recommended treatment regimen? When should we start treatment and for how long should we continue it? Should we still use retinal laser therapy? The wide range of possibilities and emerging treatment choices not only aids, but also challenges clinicians striving for evidence-based management.


2021 ◽  

Background: The distribution knowledge structure and pattern of the literature on labor analgesia in PubMed were examined. Methods: Scientific papers on labor analgesia published from 1 January, 2000 to 31 June, 2020 were retrieved. The extracted MeSH items were quantitatively analyzed by the Bibliographic Item Co-Occurrence Matrix Builder (BICOMB), and the high frequency MeSH items were identified. In gCLUTO software, repeated bisection method was used to Mountain visualisation, and the visual matrix was established. By constructing high-frequency MeSH terms co-occurrence matrix, strategic diagram and social network are further completed. Results: The search strategy yielded 2870 papers, and the number of papers published annually had changed slightly during the study period. Among all extracted MeSH terms, 42 high-frequency MeSH terms were identified by consensus, and were divided into six categories by diclustering analysis. In the strategic diagram, the methods of labor analgesia, drug doses, and routes of administration were properly presented. In contrast, statistical and numerical data on obstetric analgesia were relatively underdeveloped, and management of pain during labor was undeveloped. In the social network analysis, the position status of each component was determined by the centrality values. Conclusions: The findings on labor analgesia are relatively divergent, and the six research categories outlined in this study reflect the publication trends in the field of labor analgesia to some extent. Our quantitative bibliometric research across a 20-year span depicts the overall direction of the latest topics and provides some hints for researchers when launching new projects.


1977 ◽  
Vol 38 (02) ◽  
pp. 0399-0406 ◽  
Author(s):  
Peter N. Walsh ◽  
Richard E. Goldberg ◽  
Richard L. Tax ◽  
Larry E. Magargal

SummaryTo determine whether platelets play a role in the pathogenesis of retinal vein occlusion (RVO), platelets and coagulation were evaluated in 28 patients with RVO. Platelet coagulant activities concerned with the initiation and early stages of intrinsic coagulation were 2–4 fold increased in 9 patients with acute primary RVO but not in patients with acute secondary (10 patients) or chronic (9 patients) RVO. Platelet factor 3 activity, platelet aggregation, serotonin release by platelets and plasma coagulation were normal in all patients. Platelets may provide a trigger mechanism for venous thrombosis in the eye when local conditions permit.


1994 ◽  
Vol 72 (01) ◽  
pp. 039-043 ◽  
Author(s):  
Francesco Bandello ◽  
Silvana Vigano’ D’Angelo ◽  
Mariella Parlavecchia ◽  
Alessandra Tavola ◽  
Patrizia Della Valle ◽  
...  

SummaryA series of coagulation parameters and lipoprotein(a) (Lp(a)) were explored in plasma from 40 patients with central retinal vein occlusion (CRVO, non-ischemic type n = 12; ischemic type n = 28) free of local and systemic predisposing factors, 1 to 12 months after the acute event. Forty age- and sex-matched patients with cataract served as controls. Prothrombin fragment 1.2 (FI.2), D-dimer, FVII:C - but not FVII: Ag - were higher and fibrinogen was lower in CRVO patients than in controls. Patients with non-ischemic CRVO had higher FI .2 and FVII:C and lower heparin cofactor II than patients with ischemic CRVO. Lp(a) levels greater than 300 mg/1 were observed in 12 patients with CRVO and in 4 controls (30% vs 10%, p <0.025). Patients with high Lp(a) - consistently associated with the S2 phenotype - had higher FVII:C, FVII:C/Ag ratio, and fibrinogen than the remaining CRVO patients. Plasma FI.2 and D-dimer correlated fairly in controls (r = 0.41) and patients with normal Lp(a) levels (r = 0.55), but they did not in the group of patients with high Lp(a) (r = 0.19), where the latter parameter was negatively related to D-dimer (r = −0.55). There was no dependence of the abnormalities observed on the time elapsed from vein occlusion. The findings of activated FVII and high FI.2, D-dimer, and Lp(a) are not uncommon in patients with CRVO. Increased thrombin formation with fibrin deposition and impaired fibrinolysis may play a role in the pathophysiology of CRVO and require specific treatment


1997 ◽  
Vol 77 (01) ◽  
pp. 214-216 ◽  
Author(s):  
Tuuli Linna ◽  
Antti Ylikorkala ◽  
Kimmo E Kontula ◽  
Päivi Puska ◽  
Timo Tervo

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