scholarly journals A Systematic Review of Alternative Nicotine Delivery System (ANDS)-Based Interventions on Smoking-Related Health Outcomes Among Marginalised Population Groups.

2021 ◽  
Author(s):  
Florian Scheibein ◽  
Martina Gooney ◽  
Adrian Jones ◽  
Evan Matthews ◽  
Kevin McGirr ◽  
...  
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Evidence Synthesis ◽  
Experimental Studies ◽  
Delivery Systems ◽  
People Who Use Drugs ◽  
People Living With Hiv ◽  
Smoking Reduction ◽  
Nicotine Delivery ◽  
Best Evidence Synthesis

Abstract Background: Smoking and smoking-related disease is endemic amongst many marginalised populations such as people experiencing homelessness, people who use drugs, people living with HIV, sex workers and members of the LGBTQ+, Indigenous, Traveller and migrant communities. Alternative Nicotine Delivery Systems (ANDS)-based interventions including those using Nicotine Replacement Therapy (NRT) and Electronic Nicotine Delivery Systems (ENDS) show promise in supporting people to reduce their smoking. However, little is known about ANDS-based smoking reduction interventions with marginalised populations. This systematic review provides a best evidence synthesis of ANDS-based smoking reduction interventions to address this gap.Methods:A systematic review protocol was registered on PROSPERO (CRD42020158832) and literature review conducted through MEDLINE/PubMed, CINAHL, EMBASE, OVID SP, ScienceDirect and Google Scholar. The primary outcomes of cigarette smoking, and biochemical validation of abstinence were reported. Secondary outcomes reported included physical health, mental health and other outcomes.Results: Twenty-Nine studies were included in this review. Thirteen of the included studies were randomised controlled trials (RCTs) (n= 2828) and 16 studies were quasi controlled studies (n=1172). The sample size across the studies ranged from 9 to 775 participants. The mean reported age of participants ranged from 32.4 to 56.9 years old with an overall mean age of 39.55. A minority of study participants identified as female (33.43%; with two studies not reporting gender). A range of ANDS-interventions were found to be effective in reducing smoking amongst a range of marginalised groups. However, the overall quality of both the controlled and quasi experimental studies, as evaluated using the JBI Appraisal Tool, was found to be low.Conclusions: Studies are often evaluated as homogenous interventions although they are frequently a group of interventions and lack power analysis of the effects of individual components of the intervention effect. Several studies suggest potential mental health benefits consequent of ANDS-based intervention, though this effect is poorly explored. There is a current lack of RCTs related to ANDS-based smoking related interventions with people experiencing homelessness. Similarly, there is a lack of properly controlled RCTs exploring the use of ENDS with marginalised populations. Future studies should aim to address these deficits.

scholarly journals Elbow tendinopathy and occupational biomechanical overload: A systematic review with best‐evidence synthesis

2021 ◽  
Vol 63 (1) ◽  
Author(s):  
Stefania Curti ◽  
Stefano Mattioli ◽  
Roberta Bonfiglioli ◽  
Andrea Farioli ◽  
Francesco S. Violante
Keyword(s):  
Systematic Review ◽  
Evidence Synthesis ◽  
Best Evidence Synthesis

scholarly journals Topical glyceryl trinitrate for the treatment of tendinopathies: a systematic review

2018 ◽  
Vol 53 (4) ◽  
pp. 251-262 ◽  
Author(s):  
Dimitris Challoumas ◽  
Paul D Kirwan ◽  
Dmytro Borysov ◽  
Christopher Clifford ◽  
Michael McLean ◽  
...  
Keyword(s):  
Systematic Review ◽  
Glyceryl Trinitrate ◽  
Strong Evidence ◽  
Evidence Synthesis ◽  
Clinical Effects ◽  
Range Of Movement ◽  
Level Of Evidence ◽  
Moderate Evidence ◽  
Best Evidence Synthesis ◽  
Topical Glyceryl Trinitrate

ObjectiveTo produce a best evidence synthesis of the clinical effects of topical glyceryl trinitrate (GTN) in the treatment of tendinopathies.DesignA systematic review of published randomised controlled trials (RCTs) of the use of GTN in patients with tendinopathy.Data sourcesMEDLINE, Embase, Scopus and CINAHL from database inception to January 2018.MethodsWe examined RCTs comparing the effects of topical GTN with either placebo or other treatments on tendinopathy. Overall quality of each eligible study was determined based on a combined assessment of internal validity, external validity and precision. The level of evidence for each assessed parameter was rated based on the system by van Tulderet al.ResultsA total of 10 eligible RCTs were identified including patients with tendinopathy of the rotator cuff (n=4), wrist extensors (n=3), Achilles (n=2) and patellar (n=1) tendons. For all tendinopathies, improvements in pain were significant when comparing GTN versus placebo in the short term (<8 weeks; poor evidence). Significant improvements in midterm outcomes for treatment with GTN versus placebo included the following: patient satisfaction (strong evidence); chances of being asymptomatic with activities of daily living (strong evidence); range of movement (moderate evidence); strength (moderate evidence); pain (at night and with activity; poor evidence) and local tenderness (poor evidence). Patients treated with topical GTN reported a higher incidence of headaches than those who received placebo (moderate evidence).Conclusions and relevanceTreatment of tendinopathies with topical GTN for up to 6 months appears to be superior to placebo and may therefore be a useful adjunct to the treating healthcare professions.

scholarly journals Risk factors for, and prevention of, shoulder injuries in overhead sports: a systematic review with best-evidence synthesis

2018 ◽  
Vol 52 (20) ◽  
pp. 1312-1319 ◽  
Author(s):  
Martin Asker ◽  
Hannah L Brooke ◽  
Markus Waldén ◽  
Ulrika Tranaeus ◽  
Fredrik Johansson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Injury Prevention ◽  
Evidence Synthesis ◽  
Shoulder Injuries ◽  
Prevention Measures ◽  
Shoulder Injury ◽  
Limited Evidence ◽  
Best Evidence Synthesis ◽  
Overhead Sports

ObjectiveTo assess the evidence for risk factors and prevention measures for shoulder injuries in overhead sports.DesignSystematic review with best-evidence synthesis.Data sourcesMedline (Ovid), PubMed (complementary search), Embase (Elsevier), Cochrane (Wiley), SPORTDiscus (Ebsco) and Web of Science Core Collection (Thomson Reuters), from 1 January 1990 to 15 May 2017.Eligibility criteria for selecting studiesRandomised controlled trials, cohort studies and case-control studies on risk factors or prevention measures for shoulder injuries in overhead sports. The eligible studies were quality assessed using the Scottish Intercollegiate Guidelines Network criteria.ResultsOf 4778 studies identified, 38 were eligible for quality review and 17 met the quality criteria to be included in the evidence synthesis. One additional quality study presented a shoulder injury prevention programme. Most studies focused on baseball, lacrosse or volleyball (n=13). The risk factors examined included participation level (competition vs training) (n=10), sex (n=4), biomechanics (n=2) and external workload (n=2). The evidence for all risk factors was limited or conflicting. The effect of the prevention programme within the subgroup of uninjured players at baseline was modest and possibly lacked statistical power.ConclusionsAll investigated potential risk factors for shoulder injury in overhead sports had limited evidence, and most were non-modifiable (eg, sex). There is also limited evidence for the effect of shoulder injury prevention measures in overhead sports.PROSPERO trial registration numberCRD42015026850.

scholarly journals Dietary Interventions in the Management of Fibromyalgia: A Systematic Review and Best-Evidence Synthesis

Nutrients ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2664
Author(s):  
Ethan Lowry ◽  
Joanne Marley ◽  
Joseph G. McVeigh ◽  
Emeir McSorley ◽  
Philip Allsopp ◽  
...  
Keyword(s):  
Systematic Review ◽  
Small Sample Size ◽  
Evidence Synthesis ◽  
Nutritional Intervention ◽  
Poor Quality ◽  
Chronic Widespread Pain ◽  
Small Sample ◽  
Vegan Diet ◽  
Poor Sleep ◽  
Best Evidence Synthesis

Fibromyalgia syndrome (FMS) is characterised by chronic widespread pain alongside fatigue, poor sleep quality and numerous comorbidities. It is estimated to have a worldwide prevalence of 1.78%, with a predominance in females. Treatment interventions for fibromyalgia have limited success, leading to many patients seeking alternative forms of treatment, including modifications to their diet and lifestyle. The effectiveness of dietary changes in fibromyalgia has not been widely researched or evaluated. This systematic review identified twenty-two studies, including 18 randomised control trials (RCTs) and four cohort studies which were eligible for inclusion. In total these studies investigated 17 different nutritional interventions. Significant improvements in reported pain were observed for those following a vegan diet, as well as with the low fermentable oligo di-mono-saccharides and polyols (FODMAP) diets. Supplementation with Chlorella green algae, coenzyme Q10, acetyl-l-carnitine or a combination of vitamin C and E significantly improved measures of pain. Interpretation of these studies was limited due to the frequent poor quality of the study design, the wide heterogeneity between studies, the small sample size and a high degree of bias. Therefore, there is insufficient evidence to recommend any one particular nutritional intervention for the management of fibromyalgia and further research is needed.

scholarly journals Do dissatisfied patients have unrealistic expectations? A systematic review and best-evidence synthesis in knee and hip arthroplasty patients

2020 ◽  
Vol 5 (4) ◽  
pp. 226-240 ◽  
Author(s):  
Frederique J. Hafkamp ◽  
Taco Gosens ◽  
Jolanda de Vries ◽  
Brenda L. den Oudsten
Keyword(s):  
Systematic Review ◽  
Study Design ◽  
Clinical Success ◽  
Evidence Synthesis ◽  
Outcome Expectations ◽  
Future Research ◽  
Success Rates ◽  
Best Evidence Synthesis ◽  
Almost All ◽  
The Relationship

End-stage osteoarthritis is commonly treated with joint replacement. Despite high clinical success rates, up to 28% of patients are dissatisfied with the outcome. This best-evidence synthesis aimed to review studies with different forms of study design and methodology that examined the relationship between (fulfilment of) outcome expectations of hip and knee patients and satisfaction with outcome. A literature search was performed in PubMed, Web of Science, PsycInfo, Cochrane, and Google Scholar to identify studies conducted up to November 2017. The methodological quality of studies was assessed using the Newcastle-Ottawa Scale. In this best-evidence synthesis systematic review, the following main results could be seen. In only half of all studies were preoperative expectations associated with level of satisfaction, while in almost all studies (93%), fulfilment of expectations was related to satisfaction. The effect of met expectations did not differ between hip and knee patients or study design. Fulfilment of expectations seems to be consistently associated with patient satisfaction with outcome. Emphasis in future research must be placed on the operationalization and measurement of expectations and satisfaction to determine the (strength of the) influence of these different forms of assessment on the (existence of the) relationship. Cite this article: EFORT Open Rev 2020;5:226-240. DOI: 10.1302/2058-5241.5.190015

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