scholarly journals Sarcopenia and Coronary Heart Disease Synergistically Increase the Risk of New Onset Depressive Symptoms in Older Adults

Author(s):  
Xiaoyu Chen ◽  
Peipei Han ◽  
Xing Yu ◽  
Yuanyuan Zhang ◽  
Peiyu Song ◽  
...  

Abstract Background: It is well known that psychological and physical are very common among the elderly. This study aimed to investigate the additive effects of coronary heart disease (CHD) and sarcopenia on the risk of new onset depressive symptoms in older adults. Methods: The prospective cohort study comprised 897 Chinese community-dwelling participants who were aged 60 years and older (386 men; mean age 66.9±5.9 years) without depressive symptoms at baseline, recruited from Chadian of Tianjin, China. Sarcopenia was defined according to the Asian Working Group for Sarcopenia (AWGS) criteria. CHD was identified via medical records or new diagnosed by at least two physicians. Depressive symptoms were assessed using the Geriatric Depression Scale (GDS) ≥11. Longitudinal data on new onset depressive symptoms were collected up to 12 months after baseline.Results: We found that 103 (11.5%) of the 897 participants without depressive symptoms at baseline had developed depressive symptoms. Participants were classified into mutually exclusive groups based on sarcopenia status and CHD: normal, CHD alone, sarcopenia alone, and co-occurring groups. A logistic regression showed that the CHD alone [odd ratios (OR) = 1.81, 95% confidence interval (CI) = 1.07-3.07]], sarcopenia alone (OR = 2.77, 95% CI = 1.24-6.16), and co-occurring (OR = 7.12, 95% CI = 2.73-18.61) had higher risk of depressive symptoms than the normal group after adjusting for the covariates.Conclusions: CHD and sarcopenia synergistically increase the risk of new onset depressive symptoms in older adults. Thus, older adults may require early detection, and appropriate interventions should be implemented.

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaoyu Chen ◽  
Peipei Han ◽  
Xing Yu ◽  
Yuanyuan Zhang ◽  
Peiyu Song ◽  
...  

Abstract Background Coronary heart disease (CHD), sarcopenia and depression are common disorders that markedly impair quality of life and impose a huge financial burden on society. They are also frequently comorbid, exacerbating condition and worsening prognosis. This study aimed to investigate the additive effects of CHD and sarcopenia on the risk of new onset depressive symptoms in older adults. Methods The prospective cohort study comprised 897 Chinese community-dwelling participants who were aged 60 years and older (386 men; mean age 66.9 ± 5.9 years) without depressive symptoms at baseline, recruited from Chadian of Tianjin, China. Sarcopenia was defined according to the Asian Working Group for Sarcopenia (AWGS) criteria. CHD was identified via medical records or new diagnosed by at least two physicians. Depressive symptoms were assessed using the Geriatric Depression Scale (GDS) ≥11. Longitudinal data on new onset depressive symptoms were collected up to 12 months after baseline. Results We found that 103 (11.5%) of the 897 participants without depressive symptoms at baseline had developed depressive symptoms. Participants were classified into mutually exclusive groups based on sarcopenia status and CHD: normal, CHD alone, sarcopenia alone, and co-occurring groups. A logistic regression showed that the CHD alone [odd ratios (OR) = 1.78, 95% confidence interval (CI) = 1.05–3.02], sarcopenia alone (OR = 2.79, 95% CI = 1.26–6.22), and co-occurring (OR = 7.19, 95% CI = 2.75–18.81) had higher risk of depressive symptoms than the normal group after adjusting for the covariates. Conclusions CHD and sarcopenia synergistically increase the risk of new onset depressive symptoms in older adults. Thus, older adults may require early detection, and appropriate interventions should be implemented.


Author(s):  
Yonglin Liang ◽  
Francisco T.T. Lai ◽  
Joyce L.Y. Kwan ◽  
Wai Chan ◽  
Eng-Kiong Yeoh

Multimorbidity is associated with increased depression risks. Little research examines how physical exercise moderates this association. From an existing cohort of community-dwelling older adults in Hong Kong recruited in 2001–2003, the authors included participants who were successfully interviewed after 14 years (2015–2017). Geriatric depressive symptoms were used as the primary outcome and measured by the 15-item Geriatric Depression Scale, while multimorbidity was operationalized using a list of 19 conditions. Subscores of the Physical Activity Scale for the Elderly measuring light, moderate, and strenuous sport/recreational activities were included as moderators. In total, 1,056 participants were included, of whom 50.7% were multimorbid. Multimorbidity was associated with 12% more geriatric depressive symptoms, but strenuous physical activities were associated with a smaller risk elevation only among multimorbid patients (adjusted relative risk = 0.99, 95% confidence interval [0.98, 0.99]; p = .001). In conclusion, strenuous sport and recreational activities may attenuate the association between multimorbidity and geriatric depressive symptoms.


2008 ◽  
Vol 2 (3) ◽  
pp. 228-232 ◽  
Author(s):  
Renata Areza Fegyveres ◽  
Ana Paula Formigoni ◽  
Cláudia Sellitto Porto ◽  
Maria Teresa Carthery Goulart ◽  
Mirna Lie Hosogi Senaha ◽  
...  

Abstract The Informant Questionnaire on Cognitive Decline in the Elderly with the Proxy (IQCODE) was developed as a screening tool for cognition alterations. Objectives: 1) To verify the applicability of IQCODE in the elderly with limited schooling, 2) To verify the reliability of the responses supplied by the aged and their proxies. Methods: Individuals of a Community Group were evaluated using the Mini-Mental State Examination (MMSE), IQCODE and Geriatric Depression Scale (GDS). The IQCODE was applied to informants and proxies. Results: We analyzed 44 individuals, aged between 58-82 years (M=66.8, SD=5.97) with mean elderly-schooling level of 3.75, SD=2.82 and 44 proxies aged 44.5 (SD=13.3), with mean schooling level of 8.25 (SD=4.3). The mean GDS was 8.22, SD=4.90 and 13 participants presented a score suggestive of depressive symptoms. The mean elderly IQCODE score was 3.26, SD=0.69 and 3.21, SD=0.65, for proxy responses. There was no statistical difference between these means. On the MMSE, the mean score was 24.20, SD=4.14 and 18 participants presented scores below the cut-off. The IQCODE answers by the elderly in this latter group were more congruent with MMSE than the answers of proxies. Conclusions: The applicability of the IQCODE in a population with little schooling was verified in that the proxy-report was similar to the elderly report. We can affirm that the elderly answers were more accurate than the proxies, as they were closer to MMSE score. The inclusion of a greater number of participants from community-dwelling settings is necessary to confirm the results obtained in this study.


Author(s):  
Dan Song ◽  
Doris S.F. Yu ◽  
Polly W.C. Li ◽  
Qiuhua Sun

High-level depressive symptoms have been reported in individuals with mild cognitive impairment (MCI), resulting in increased risk of progression to dementia. However, studies investigating the correlates of depressive symptoms among this population are scarce. This study aimed to investigate the significant socio-demographic, lifestyle-related and disease-related correlates of depressive symptoms among this cohort. Cross-sectional data were obtained from a sample of 154 Chinese community-dwelling older adults with MCI. MCI subjects were screened by the Montreal Cognitive Assessment. Depressive symptoms were measured by the Geriatric Depression Scale. Possible correlates of depressive symptoms in individuals with MCI were explored by multiple linear regressions. The prevalence of depressive symptoms among Chinese older adults with MCI was 31.8%. In multiple regression analysis, poor perceived positive social interaction, small social network, low level of physical activity, poor functional status, subjective memory complaint, and poor health perception were correlated with depressive symptoms. The findings highlight that depressive symptoms are sufficient to warrant evaluation and management in older adults with MCI. Addressing social isolation, assisting this vulnerable group in functional and physical activities, and cultivating a positive perception towards cognitive and physical health are highly prioritized treatment targets among individuals with MCI.


2011 ◽  
Vol 23 (6) ◽  
pp. 950-960 ◽  
Author(s):  
Kathryn Betts Adams

ABSTRACTBackground: In light of inconsistencies in cut points for identifying non-major depression, this study examined the classification efficiency of the Geriatric Depression Scale (GDS and GDS-15) total scores and individual items, and four additional depressive symptoms for identification of subthreshold, minor, or criterion depression among 166 vulnerable residents of congregate housing.Methods: Depression (combined categories of major depressive episode, minor, or subthreshold depression) was determined by the Mini-International Neuropsychiatric Interview (MINI) diagnostic interview depression module administered by telephone to 166 older residents of congregate housing facilities who also completed the 30-item GDS and four other yes/no potential indicators of geriatric depression. Classification agreement and ROC curve analysis for the full and 15-item GDS scale scores were calculated. Individual item hit rates for MINI criterion were calculated for GDS items and four new items.Results: GDS and GDS-15 at standard cut points had 70–75% agreement with MINI. Best sensitivity and specificity were obtained at lower than standard cut points. Some GDS Withdrawal, Apathy, lack of Vigor (WAV) and cognitive items obtained very low hit rates. New items “I just don't feel like myself” and “I feel I am a burden to others” better discriminated MINI depression than most GDS items and had good item-to-total correlations with the GDS.Conclusions: Diagnostic criteria and GDS screen had partial agreement. Some GDS items did not adequately represent depression among functionally impaired or oldest old older adults. Feeling one is a burden and the sense of feeling “different” from usual may be useful indicators of depression among vulnerable older adults.


2021 ◽  
Vol 20 (4) ◽  
pp. 170-216
Author(s):  
Edison Vitório de Souza Júnior ◽  
Sterline Therrier ◽  
Cristiane dos Santos Silva ◽  
Bianca de Moura Peloso-Carvalho ◽  
Lais Reis Siqueira ◽  
...  

Objetivo: Analizar la asociación entre sexualidad y variables biosociodemográficas y síntomas depresivos en adultos mayores. Método: Se trata de un estudio seccional diseñado con 292 personas mayores. La recolección de datos se realizó entre agosto y octubre de 2020. Se utilizó la Escala de Experiencias Sexuales y Afectivas de Ancianos y la Escala de Depresión Geriátrica. Se utilizaron pruebas de Mann-Whitney, correlación de Spearman y pruebas de Kruskal-Wallis, adoptando un intervalo de confianza del 95% para todos los análisis estadísticos.Resultados: Predominaron los varones (52,1%) y entre 60 y 64 años (46,6%). La prevalencia de síntomas depresivos fue del 30,1% para los casos leves y del 8,6% para los graves. Los ancianos con síntomas depresivos experimentaron peor el acto sexual, las relaciones afectivas y las adversidades físicas y sociales relacionadas con la sexualidad. La única dimensión de la sexualidad que se asoció con las variables biosociodemográficas fue el acto sexual, mostrando que es mejor vivido por los ancianos en unión estable (p = 0.023) y entre quienes conviven con la pareja por un período ≤ 5 años, en comparación con los mayores de 20 años (p = 0,001). Además, solo la dimensión acto sexual se correlacionó negativamente y con magnitud moderada entre los síntomas depresivos graves (ρ = -0,442; p = 0,027), lo que indica que estas dos variables exhiben comportamientos inversamente proporcionales. Conclusión: La sexualidad se asocia con algunas variables biosociodemográficas y se correlaciona con síntomas depresivos severos en ancianos. Objective: To analyze the association of sexuality with the bio-sociodemographic variables and depressive symptomatology in the elderly. Method: This is a sectional study designed with 292 elderly people. Data were collected between August and October 2020. The Elderly Affective and Sexual Experiences Scale and the Geriatric Depression Scale were used. Mann-Whitney, Spearman correlation, and Kruskal-Wallis tests were used, adopting a 95% confidence interval for all statistical analyses.Results: The participants were predominantly male (52.1%) and aged between 60 and 64 years (46.6%). The prevalence of depressive symptoms was 30.1% for mild cases and 8.6% for severe cases. The elderly with depressive symptomatology experienced worse the sexual act, affective relationships, and physical and social adversities related to sexuality. The only dimension of sexuality that was associated with the bio-sociodemographic variables was the "sexual act," proving to be better experienced by the elderly in stable unions (p = 0.023) and among those who live with their partner for a period ≤ 5 years, when compared to those with living together for more than 20 years (p = 0.001). In addition, only the Sexual act dimension correlated negatively and with moderate magnitude with severe depressive symptoms (ρ = -0.442; p = 0.027), indicating that these two variables present inversely proportional behaviors.Conclusion: Sexuality is associated with some bio-sociodemographic variables and correlated with severe depressive symptoms among the elderly. Objetivo: Analisar a associação entre a sexualidade com as variáveis biosociodemográficas e sintomatologia depressiva em idosos. Método: Trata-se de um estudo seccional delineado com 292 idosos. Realizou-se a coleta de dados entre agosto e outubro de 2020. Foi utilizada a Escala de Vivências Afetivas e Sexuais do Idoso e a Escala de Depressão Geriátrica. Utilizou-se os testes de Mann-Whitney, correlação de Spearman e Kruskal-Wallis, adotando intervalo de confiança de 95% para todas as análises estatísticas.Resultados: Predominaram-se os participantes do sexo masculino (52,1%) e com idade entre 60 e 64 anos (46,6%). A prevalência de sintomatologia depressiva foi de 30,1% para os casos leves e 8,6% para os severos. Os idosos com sintomatologias depressivas pior vivenciaram o ato sexual, as relações afetivas e as adversidades física e social relacionadas à sexualidade. A única dimensão da sexualidade que se associou com as variáveis biosociodemográficas foi o ato sexual, demonstrando ser melhor vivenciada pelos idosos em união estável (p=0,023) e entre aqueles que convivem com o parceiro por um período ≤ 5 anos, quando comparados a aqueles com convivência superior a 20 anos (p=0,001). Além disso, somente a dimensão ato sexual se correlacionou de maneira negativa e com moderada magnitude entre os sintomas depressivos severos (ρ= -0,442; p=0,027), indicando que essas duas variáveis apresentam comportamentos inversamente proporcionais.Conclusão: A sexualidade está associada à algumas variáveis biosociodemográficas e correlacionada às sintomatologias depressivas severas entre os idosos.


2020 ◽  
Vol 9 (3) ◽  
pp. 795
Author(s):  
Michio Maruta ◽  
Hyuma Makizako ◽  
Yuriko Ikeda ◽  
Hironori Miyata ◽  
Atsushi Nakamura ◽  
...  

The aim of this cross-sectional study was to investigate relationships between individuals’ ratings of satisfaction and performance of activities that they found meaningful and depressive symptoms. Data was obtained from 806 older adults (mean age 74.9 ± 6.3 years, women = 63.0%) who participated in a community-based health check survey (Tarumizu Study 2018). Participants selected meaningful activities from 95 activities using the Aid for Decision-Making in Occupation Choice and evaluated their satisfaction and performance. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale (GDS-15) and defined by a GDS-15 score of ≥5. Non-linear logistic regression analyses were used separately by gender to examine the association between satisfaction and performance of meaningful activities and depressive symptoms. The prevalence of depressive symptoms was 15.8%. We found no significant difference between meaningful activity choice between older adults with depressive symptoms and those without, in both men and women. After adjusting for potential covariates, satisfaction was associated with depressive symptoms in both men (OR 0.52, 95% CI 0.35–0.77) and women (OR 0.67, 95% CI 0.49–0.91), but performance was limited in women (OR 0.87, 95% CI 0.77–0.99). Our findings suggest that depressive symptoms are associated with satisfaction in meaningful activities regardless of activity categories.


Author(s):  
Christian Oswaldo Acosta Quiroz ◽  
Raquel García-Flores ◽  
Sonia Beatriz Echeverría-Castro

The objective of this study was to evaluate the reliability and validity of the Geriatric Depression Scale in its 15-item version (GDS-15) in Mexican older adults. Participants included 1178 older adults between the ages of 60 and 94 ( M = 69.16, SD = 7.69); 53.9% were women and 55.8% were married or with a partner. They completed the GDS-15, a subjective well-being scale, and a quality-of-life questionnaire. A Kuder–Richardson coefficient of .80 was obtained, which indicates an acceptable internal consistency of the GDS-15, as well as evidence of divergent validity with significant correlations of −.783 with subjective well-being and −.569 with quality of life, in addition to concurrent validity when discriminating between participants with low scores from those with high scores of depressive symptoms. The need for a simple screening tool such as the GDS-15 that helps in the identification of depressive symptoms in Mexican older adults is underlined.


2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Alcibiades E. Villarreal ◽  
Shantal Grajales ◽  
Lineth Lopez ◽  
Gabrielle B. Britton ◽  
Panama Aging Research Initiative

Cognitive impairment and depression are common mental health problems among the elderly, although few studies have examined their cooccurrence in older adults in Latin America. The purpose of this study was to examine cognitive impairment, depression, and cooccurrence of the two conditions and associated factors in a sample of older adults in Panama. This study included 304 community-dwelling elderly (≥65 years) individuals. Participants underwent a clinical interview and assessments of cognitive function by the Minimental State Examination and depressive symptoms by the Geriatric Depression Scale. Limitations in basic (BADL) and instrumental (IADL) activities in daily living and the presence of chronic illnesses were recorded. Multinomial regression analysis revealed that cooccurrence of cognitive impairment and depressive symptoms was explained by increasing age (OR: 3.2, 95% CI: 1.20, 8.30), low education (OR: 3.3, 95% CI: 1.33, 8.38), having four or more chronic conditions (OR: 11.5, 95% CI: 2.84, 46.63), and BADL limitations (OR: 5.0, 95% CI: 1.26, 19.68). Less education and limitations in BADL and IADL increased the odds of cognitive impairment alone, while less education and three or more chronic conditions increased the odds of depression alone. These findings underscore the relevance of assessing cognitive impairment in the elderly as part of a long-term approach to managing depression and vice versa.


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