scholarly journals Sarcopenia and coronary heart disease synergistically increase the risk of new onset depressive symptoms in older adults

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaoyu Chen ◽  
Peipei Han ◽  
Xing Yu ◽  
Yuanyuan Zhang ◽  
Peiyu Song ◽  
...  

Abstract Background Coronary heart disease (CHD), sarcopenia and depression are common disorders that markedly impair quality of life and impose a huge financial burden on society. They are also frequently comorbid, exacerbating condition and worsening prognosis. This study aimed to investigate the additive effects of CHD and sarcopenia on the risk of new onset depressive symptoms in older adults. Methods The prospective cohort study comprised 897 Chinese community-dwelling participants who were aged 60 years and older (386 men; mean age 66.9 ± 5.9 years) without depressive symptoms at baseline, recruited from Chadian of Tianjin, China. Sarcopenia was defined according to the Asian Working Group for Sarcopenia (AWGS) criteria. CHD was identified via medical records or new diagnosed by at least two physicians. Depressive symptoms were assessed using the Geriatric Depression Scale (GDS) ≥11. Longitudinal data on new onset depressive symptoms were collected up to 12 months after baseline. Results We found that 103 (11.5%) of the 897 participants without depressive symptoms at baseline had developed depressive symptoms. Participants were classified into mutually exclusive groups based on sarcopenia status and CHD: normal, CHD alone, sarcopenia alone, and co-occurring groups. A logistic regression showed that the CHD alone [odd ratios (OR) = 1.78, 95% confidence interval (CI) = 1.05–3.02], sarcopenia alone (OR = 2.79, 95% CI = 1.26–6.22), and co-occurring (OR = 7.19, 95% CI = 2.75–18.81) had higher risk of depressive symptoms than the normal group after adjusting for the covariates. Conclusions CHD and sarcopenia synergistically increase the risk of new onset depressive symptoms in older adults. Thus, older adults may require early detection, and appropriate interventions should be implemented.

2020 ◽  
Author(s):  
Xiaoyu Chen ◽  
Peipei Han ◽  
Xing Yu ◽  
Yuanyuan Zhang ◽  
Peiyu Song ◽  
...  

Abstract Background: It is well known that psychological and physical are very common among the elderly. This study aimed to investigate the additive effects of coronary heart disease (CHD) and sarcopenia on the risk of new onset depressive symptoms in older adults. Methods: The prospective cohort study comprised 897 Chinese community-dwelling participants who were aged 60 years and older (386 men; mean age 66.9±5.9 years) without depressive symptoms at baseline, recruited from Chadian of Tianjin, China. Sarcopenia was defined according to the Asian Working Group for Sarcopenia (AWGS) criteria. CHD was identified via medical records or new diagnosed by at least two physicians. Depressive symptoms were assessed using the Geriatric Depression Scale (GDS) ≥11. Longitudinal data on new onset depressive symptoms were collected up to 12 months after baseline.Results: We found that 103 (11.5%) of the 897 participants without depressive symptoms at baseline had developed depressive symptoms. Participants were classified into mutually exclusive groups based on sarcopenia status and CHD: normal, CHD alone, sarcopenia alone, and co-occurring groups. A logistic regression showed that the CHD alone [odd ratios (OR) = 1.81, 95% confidence interval (CI) = 1.07-3.07]], sarcopenia alone (OR = 2.77, 95% CI = 1.24-6.16), and co-occurring (OR = 7.12, 95% CI = 2.73-18.61) had higher risk of depressive symptoms than the normal group after adjusting for the covariates.Conclusions: CHD and sarcopenia synergistically increase the risk of new onset depressive symptoms in older adults. Thus, older adults may require early detection, and appropriate interventions should be implemented.


Author(s):  
Dan Song ◽  
Doris S.F. Yu ◽  
Polly W.C. Li ◽  
Qiuhua Sun

High-level depressive symptoms have been reported in individuals with mild cognitive impairment (MCI), resulting in increased risk of progression to dementia. However, studies investigating the correlates of depressive symptoms among this population are scarce. This study aimed to investigate the significant socio-demographic, lifestyle-related and disease-related correlates of depressive symptoms among this cohort. Cross-sectional data were obtained from a sample of 154 Chinese community-dwelling older adults with MCI. MCI subjects were screened by the Montreal Cognitive Assessment. Depressive symptoms were measured by the Geriatric Depression Scale. Possible correlates of depressive symptoms in individuals with MCI were explored by multiple linear regressions. The prevalence of depressive symptoms among Chinese older adults with MCI was 31.8%. In multiple regression analysis, poor perceived positive social interaction, small social network, low level of physical activity, poor functional status, subjective memory complaint, and poor health perception were correlated with depressive symptoms. The findings highlight that depressive symptoms are sufficient to warrant evaluation and management in older adults with MCI. Addressing social isolation, assisting this vulnerable group in functional and physical activities, and cultivating a positive perception towards cognitive and physical health are highly prioritized treatment targets among individuals with MCI.


2015 ◽  
Vol 28 (4) ◽  
pp. 591-601 ◽  
Author(s):  
Yu-Chen Chang ◽  
Wen-Chen Ouyang ◽  
Mei-Chun Lu ◽  
Jung-Der Wang ◽  
Susan C. Hu

ABSTRACTBackground:Depression is closely associated with quality of life (QOL) in older adults. Being elderly and exhibiting mild depressive symptoms may not lead to a depression diagnosis, but these attributes are clinically important. However, the extent to which these factors influence QOL and its determinants in older adults remains unclear.Methods:Questionnaires were administered to people aged 65 years or older at community senior centers in Taiwan to collect socio-demographic information and to assess results from the brief version of the World Health Organization's Quality of Life instrument (WHOQOL-BREF), Modified Barthel Index (MBI), 15-item Geriatric Depression Scale (GDS), and Mini-Mental State Examination (MMSE). Levels of depressive symptoms were classified as no depressive symptoms (NDS), lower level of depressive symptoms (LLDS), and higher level of depressive symptoms (HLDS), corresponding to GDS = 0, 1≦GDS≦5, and GDS>5, respectively. Multiple linear regression analyses were conducted to assess associations between the WHOQOL-BREF and its covariates for different levels of depressive symptoms.Results:A total of 454 older adults participated. The GDS and MBI scores significantly affected the WHOQOL-BREF physical and psychological domain scores in the LLDS group. Gender influenced the WHOQOL-BREF scores in the NDS group, and increased age demonstrated protective effects on the three domains in the HLDS group. Moreover, the association between the WHOQOL-BREF and its covariates varied for different levels of depressive symptoms.Conclusions:Treatment for depressive symptoms is of high priority, and early recognition of and appropriate intervention for mild depressive symptoms may improve community-dwelling older adults’ QOLs.


2020 ◽  
Vol 9 (3) ◽  
pp. 795
Author(s):  
Michio Maruta ◽  
Hyuma Makizako ◽  
Yuriko Ikeda ◽  
Hironori Miyata ◽  
Atsushi Nakamura ◽  
...  

The aim of this cross-sectional study was to investigate relationships between individuals’ ratings of satisfaction and performance of activities that they found meaningful and depressive symptoms. Data was obtained from 806 older adults (mean age 74.9 ± 6.3 years, women = 63.0%) who participated in a community-based health check survey (Tarumizu Study 2018). Participants selected meaningful activities from 95 activities using the Aid for Decision-Making in Occupation Choice and evaluated their satisfaction and performance. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale (GDS-15) and defined by a GDS-15 score of ≥5. Non-linear logistic regression analyses were used separately by gender to examine the association between satisfaction and performance of meaningful activities and depressive symptoms. The prevalence of depressive symptoms was 15.8%. We found no significant difference between meaningful activity choice between older adults with depressive symptoms and those without, in both men and women. After adjusting for potential covariates, satisfaction was associated with depressive symptoms in both men (OR 0.52, 95% CI 0.35–0.77) and women (OR 0.67, 95% CI 0.49–0.91), but performance was limited in women (OR 0.87, 95% CI 0.77–0.99). Our findings suggest that depressive symptoms are associated with satisfaction in meaningful activities regardless of activity categories.


Author(s):  
Christian Oswaldo Acosta Quiroz ◽  
Raquel García-Flores ◽  
Sonia Beatriz Echeverría-Castro

The objective of this study was to evaluate the reliability and validity of the Geriatric Depression Scale in its 15-item version (GDS-15) in Mexican older adults. Participants included 1178 older adults between the ages of 60 and 94 ( M = 69.16, SD = 7.69); 53.9% were women and 55.8% were married or with a partner. They completed the GDS-15, a subjective well-being scale, and a quality-of-life questionnaire. A Kuder–Richardson coefficient of .80 was obtained, which indicates an acceptable internal consistency of the GDS-15, as well as evidence of divergent validity with significant correlations of −.783 with subjective well-being and −.569 with quality of life, in addition to concurrent validity when discriminating between participants with low scores from those with high scores of depressive symptoms. The need for a simple screening tool such as the GDS-15 that helps in the identification of depressive symptoms in Mexican older adults is underlined.


Author(s):  
Yonglin Liang ◽  
Francisco T.T. Lai ◽  
Joyce L.Y. Kwan ◽  
Wai Chan ◽  
Eng-Kiong Yeoh

Multimorbidity is associated with increased depression risks. Little research examines how physical exercise moderates this association. From an existing cohort of community-dwelling older adults in Hong Kong recruited in 2001–2003, the authors included participants who were successfully interviewed after 14 years (2015–2017). Geriatric depressive symptoms were used as the primary outcome and measured by the 15-item Geriatric Depression Scale, while multimorbidity was operationalized using a list of 19 conditions. Subscores of the Physical Activity Scale for the Elderly measuring light, moderate, and strenuous sport/recreational activities were included as moderators. In total, 1,056 participants were included, of whom 50.7% were multimorbid. Multimorbidity was associated with 12% more geriatric depressive symptoms, but strenuous physical activities were associated with a smaller risk elevation only among multimorbid patients (adjusted relative risk = 0.99, 95% confidence interval [0.98, 0.99]; p = .001). In conclusion, strenuous sport and recreational activities may attenuate the association between multimorbidity and geriatric depressive symptoms.


2014 ◽  
Vol 26 (9) ◽  
pp. 1511-1519 ◽  
Author(s):  
Sébastien Grenier ◽  
Marie-Christine Payette ◽  
Francis Langlois ◽  
Thien Tuong Minh Vu ◽  
Louis Bherer

ABSTRACTBackground:Falls and depression are two major public health problems that affect millions of older people each year. Several factors associated with falls are also related to depressive symptoms such as medical conditions, sleep quality, use of medications, cognitive functioning, and physical capacities. To date, studies that investigated the association between falls and depressive symptoms did not control for all these shared factors. The current study addresses this issue by examining the relationship between falls and depression symptoms after controlling for several confounders.Methods:Eighty-two community-dwelling older adults were enrolled in this study. The Geriatric Depression Scale (GDS-30) was used to evaluate the presence of depressive symptoms, and the following question was used to assess falls: “Did you fall in the last 12 months, and if so, how many times?”Results:Univariate analyses indicated that the number of falls was significantly correlated with gender (women), fractures, asthma, physical inactivity, presence of depressive symptoms, complaints about quality of sleep, use of antidepressant drugs, and low functional capacities. Multivariate analyses revealed that depressive symptoms were significantly and independently linked to recurrent falls after controlling for confounders.Conclusions:Results of the present study highlight the importance of assessing depressive symptoms during a fall risk assessment.


2022 ◽  
Vol 21 (1) ◽  
pp. 433-472
Author(s):  
Edison Vitório de Souza Júnior ◽  
Diego Pires Cruz ◽  
Cristiane dos Santos Silva ◽  
Randson Souza Rosa ◽  
Bianca de Moura Peloso-Carvalho ◽  
...  

Objective: To analyze the association between depressive symptoms and quality of life in older adults. Method: Cross-sectional study carried out between July and October, in 2020, with 596 older adults who answered three instruments, namely: bio-sociodemographic, Geriatric Depression Scale and WHOQOL-Old. Data were analyzed using Chi-square, Kruskal-Wallis, Spearman correlation and linear regression tests, considering a 95% confidence interval (p<0.05). Results: Depressive symptoms were negatively and statistically significantly associated with all facets of quality of life: sensory abilities (β= -1.922 [CI95%= -2.328 – -1.517]); autonomy (β= -2.410 [CI95%= -2.755 - -2.064]); past, present and future activities (β= -3.534 [CI95%= -3.879 – -3.189]); social participation (β= -3.436 [CI95%= -3.816 – -3.056]); death and dying (β= -2.260 [CI95%= -2.792 – -1.728]) and intimacy (β= -3.547 [CI95%= -3,900 – -3.194]). Conclusion: The presence of depressive symptoms is negatively associated with the quality of life of older adults, thus requiring interventions in this area. Objetivo: Analizar la asociación entre sintomatología depresiva y calidad de vida de adultos mayores.Método: Estudio transversal realizado entre julio y octubre de 2020 con 596 personas mayores que respondieron a tres instrumentos: biosociodemográfico, Escala de Depresión Geriátrica y WHOQOL-Old. Los datos se analizaron mediante pruebas de Chi-cuadrado, Kruskal-Wallis, correlación de Spearman y regresión lineal, considerando un intervalo de confianza del 95% (p<0,05).Resultados: La sintomatología depresiva se asoció de forma negativa y estadísticamente significativa con todas las facetas de la calidad de vida: habilidades sensoriales (β= -1,922 [IC95%= -2,328 – -1,517]); autonomía (β= -2,410 [IC95%= -2,755 – -2,064]); actividades pasadas, presentes y futuras (β= -3,534 [IC95%= -3,879 – -3,189]); participación social (β= -3,436 [IC95%= -3,816 – -3,056]); muerte y morir (β= -2,260 [IC95%= -2,792 – -1,728]) e intimidad (β= -3,547 [IC95%= -3,900 – -3,194]).Conclusión: La presencia de sintomatologías depresivas se asocia negativamente con la calidad de vida de las personas mayores, por lo que requiere intervenciones en este ámbito. Objetivo: Analisar a associação entre ecesitando ía ecesitan e qualidade de vida de idosos. Método: Estudo seccional realizado entre julho e outubro de 2020 com 596 idosos que responderam três instrumentos: biosociodemográfico, Escala de Depressão Geriátrica e WHOQOL-Old. Os dados foram analisados com os testes de Qui-quadrado, Kruskal-Wallis, correlação de Spearman e regressão linear, considerando um intervalo de confiança de 95% (p<0,05). Resultados: A sintomatologia depressiva se associou de forma negativa e estatisticamente significante com todas as facetas da qualidade de vida: habilidades sensoriais (β= -1,922 [IC95%= -2,328 – -1,517]); autonomia (β= -2,410 [IC95%= -2,755 – -2,064]); atividades passadas, presentes e futuras (β= -3,534 [IC95%= -3,879 – -3,189]); participação social (β= -3,436 [IC95%= -3,816 – -3,056]); morte e morrer (β= -2,260 [IC95%= -2,792 – -1,728]) e intimidade (β= -3,547 [IC95%= -3,900 – -3,194]). Conclusão: : A presença de sintomatologias depressivas está associada negativamente à qualidade de vida dos idosos, necessitando, portanto, de intervenções nessa área.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 788-788
Author(s):  
Milan Chang ◽  
Hrafnhildur Eymundsdottir ◽  
Alfons Ramel ◽  
Sigurveig Sigurdardottir ◽  
Vilmundur Gudnasson ◽  
...  

Abstract Background Depressive symptoms in older adults are associated with socioeconomic status (SES), medical care, and physical activity. However, there is little evidence on the longitudinal association between level of leisure activity (LA) and physical activity (PA) with depressive symptoms among community-dwelling older adults in Iceland. The study examined an association of LA and PA at baseline with high depressive symptoms (HGDS) assessed after 5 years of follow-up among community-dwelling older adults. Methods A large community-based population residing in Reykjavik, Iceland participated in a longitudinal study with 5 years of follow-up (n=2957, 58% women, 74.9±4.8 yrs). Those with HGDS or dementia at baseline were excluded from the analysis. The reported activity was categorized into 2 groups as no-activity versus any-activity. Depressive symptoms were assessed by the 15-item Geriatric Depression Scale (GDS) on average 5 years later. Results After adjusting for demographic and health-related risk factors, those who reported having any LA had significantly fewer HGDS after the follow-up of 5 years (6 or higher GDS scores, Odds Ratio (OR) = 0.46, 95% Confidence Interval (CI): 0.27 ~ 0.76, P = 0.003). However, reporting any PA at baseline was not significantly associated with HGDS (OR = 0.71, 95% CI: 0.51 ~ 1.00, P = 0.053). Conclusion Our study shows that any LA among older adults is associated with having less depressive symptoms 5 years later among community-dwelling older adults while having any PA was not associated with depressive symptoms after 5 years of follow-up.


2019 ◽  
Vol 32 (2) ◽  
pp. 97-103 ◽  
Author(s):  
Ali Ezzati ◽  
Mindy J. Katz ◽  
Carol A. Derby ◽  
Molly E. Zimmerman ◽  
Richard B. Lipton

Background: There is increasing evidence that depressive symptoms are associated with increased risk of cognitive impairment and dementia in older adults. In current study, we aimed to investigate the effect of depressive symptoms on incident Alzheimer disease and all-cause dementia in a community sample of older adults. Methods: Participants were 1219 older adults from the Einstein Aging Study, a longitudinal cohort study of community-dwelling older adults in Bronx County, New York. The Geriatric Depression Scale (GDS, 15-item) was used as a measure of depressive symptoms. The primary outcome was incident dementia diagnosed using the Diagnostic and Statistical Manual, Fourth Edition, criteria. Cox proportional hazard models were used to estimate the risk of incident dementia as a function of GDS score for the whole population and also for 2 different time intervals, <3 years and ≥3 years after baseline assessment. Results: Among participants, 132 individuals developed dementia over an average 4.5 years (standard deviation [SD] = 3.5) of follow-up. Participants had an average age of 78.3 (SD = 5.4) at baseline, and 62% were women. Among all participants, after controlling for demographic variables and medical comorbidities, a 1-point increase in GDS was associated with higher incidence of dementia (hazard ratio [HR] = 1.11, P = .007). After up to 3 years of follow-up, depressive symptoms were not significantly associated with dementia incidence (HR = 1.09; P = .070). However, after more than 3 years, GDS score was a significant predictor of incident dementia (HR = 1.13, P = .028). Conclusions: Our results suggest that depressive symptoms are associated with an increased risk of incident dementia in older adults.


Sign in / Sign up

Export Citation Format

Share Document