scholarly journals Poor Nutritional Status Among Human Filarial Lymphedema Patients in Ghana: A Cross-Sectional Study

Author(s):  
Gloria Ofosu Tenkorang ◽  
Emmanuel Kobla Atsu Amewu ◽  
Samuel Opoku Asiedu ◽  
Priscilla Kini ◽  
Bill Clinton Aglomasa ◽  
...  

Abstract Background Lymphatic filariasis (LF) is a neglected tropical disease with several infection phenotypes. In addition to mass drug administration, host immune response contributes to microfilariae clearance. An important influence of immunity, nutritional status, remains to be evaluated among filarial lymphedema patients. This study sought to assess the nutritional status of LF patients and its association with the pathology. Methods As cross-sectional study was conducted to determine the nutrition status of lymphedema patients in Ahanta West, Ghana. To obtain sociodemographic and nutrition data, a structured questionnaire was administered to the study participants. Anthropometry and 24-hour food recall were used to assess the nutritional status of participants. Results While all and 71 (82.6%) had adequate carbohydrate and protein intakes respectively, 83 (96.5%) had inadequate intake of fat. There were widespread inadequate nutrients intakes that were associated with stage of lymphedema: fat, r = -0.267, p = .024; carbohydrate, r = 0.305, p = .010; sodium, r = -0.259, p = .029; copper, r = -0.249, p = .036; selenium, r = -0.265, p = .025; pantothenic acid, r = -0.265, p = .025; vitamin B6, r = -0.270, p = .023; vitamin B12, r = -0.288, p = .015; and vitamin A, r = -0.276, p = .020. Conclusion The study shows widespread malnutrition among the participants. A nutritional intervention is recommended to complement current management strategies of filarial lymphedema.

2016 ◽  
Vol 65 (2) ◽  
pp. 333-337 ◽  
Author(s):  
Shengkang Zhang ◽  
Hanfeng Tang ◽  
Cai Gong ◽  
Jiang Liu ◽  
Jindong Chen

The chemokine (C-X3-C motif) ligand 1 (CX3CL1), also named fractalkine (FKN), has been implicated in psychiatric disorders and functions as a novel adipocytokine. However, no attention has been paid to the role of FKN in anorexia nervosa (AN). The current study was performed to explore FKN levels in AN to determine its role in the involvement of AN. A total of 96 girls aged 11–18 years with AN (n=34), healthy controls (HC; n=32) and simple obesity (OB, n=30) were enrolled in the cross-sectional study. Blood samples were collected during the fasting state. Serum FKN concentrations were determined using ELISA. The skinfold thickness (TSF) of the biceps and triceps as well as mid-arm muscle circumference (MAMC) were used to determine the nutritional status. Our results showed that serum FKN levels were significantly lower in the AN group than in the control and OB groups. After adjusting for body mass index (BMI), FKN concentrations in the AN group were statistically higher than in the HC and OB groups. Significant correlations between serum FKN and body weight, BMI, Cole index and serum insulin were observed. In addition, serum FKN levels were positively related to TSF and MAMC in all subjects. Serum FKN concentrations are attenuated in girls with AN compared with healthy adolescents and are positively related to nutritional status. The lower FKN levels may be regulated by nutrition status and response to starvation. After adjusting for BMI, higher FKN levels may reflect that persistent inflammation is present in patients with AN.


Nutrients ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 281 ◽  
Author(s):  
Claudio Tana ◽  
Fulvio Lauretani ◽  
Andrea Ticinesi ◽  
Luciano Gionti ◽  
Antonio Nouvenne ◽  
...  

The assistance to older community-dwellers provided by family caregivers is crucial for the maintenance of an acceptable quality of life, especially when dementia is present. The caregiver burden may be extremely high, but few data are available on what patient domains mainly affect the caregiver. The aim of this cross-sectional study, performed in older outpatients, was to examine the impact of cognitive, physical and nutritional status of elderly community-dwellers on the caregiver burden, as evaluated by the Caregiver Burden Inventory (CBI). A group of 406 elderly outpatients (161 M, 245 F, mean age of 83.20 ± 6.40) was enrolled. A significant correlation was observed between Mini Nutritional Assessment Instrument-Short Form (MNA-SF) and CBI (r = −0.34; p < 0.001), suggesting that a poor nutritional status is significantly associated with the caregiver burden. There was also a significant correlation between CBI and Short Physical Performance Battery score (r = −0.29; p < 0.001), hand grip strength (r = −0.25; p < 0.001), Mini-Mental State Examination score (r = −0.39; p < 0.001), Geriatric Depression Scale (r = 0.23; p < 0.001), Body Mass Index (BMI) (r = 0.01; p = 0.03), Activities of Daily Living and Instrumental Activities of Daily Living (ADL/IADL) (r = −0.61 and −0.62, respectively; p < 0.001), and with the 4-m walking speed (r = −0.42; p < 0.001). In the multivariate analysis, only the relationships of the CBI (in particular the physical subcomponent) with ADL, IADL and MNA-SF remained statistically significant (β ± SE −0.89 ± 0.20, p < 0.001; −0.58 ± 0.15, p < 0.001 and −0.25 ± 0.11, p = 0.02, respectively). The relationship between CBI and BMI remained statistically significant only for the physical subcomponent (β ± SE 0.14 ± 0.05; p = 0.006). Thus, in this study, we confirmed that the impairment in the activities of daily living is associated with a significant impact on the caregiver burden, and we found also that a poor nutritional status of the older outpatient is independently more associated with the caregiver burden than cognitive and physical disability. The combined evaluation of both patients and caregivers can improve the knowledge and assistance to the elderly subjects.


2019 ◽  
Author(s):  
Berhanu Elfu Feleke ◽  
Teferi Elfu Feleke ◽  
Fantahun Biadglegne

Abstract Background Each year, more than 13.7 million people became an active case of tuberculosis and more than 1.5 million cases of tuberculosis patient will die. The association between tuberculosis and malnutrition is bi-directional, tuberculosis leads the patient to malnutrition, and malnutrition increases the risk of developing active tuberculosis by 6 to 10 times higher. Improving the nutrition of individual greatly reduces tuberculosis. The objectives of this study were to assess the nutritional status and determinants of tuberculosis patients. Methods A comparative cross-sectional study design was implemented. The sample size was calculated using Epi-info software. The data were collected from July 2015- May 2018. The data were collected by interviewing method, measuring anthropometrics indicators and collecting the stool and blood samples. The data were entered into the computer using Epi-info software and analyzed using SPSS software. Descriptive statistics were used to identify the proportion of malnutrition. Binary logistic regression was used to identify the determinants of malnutrition. Results A total of 5045 study participants were included giving the response rate of 93.1%. The prevalence of underweight among tuberculosis patients was 57.17% (95% CI: 54.80% -59.54%) and 88.52% of tuberculosis patients were anemic. The prevalence of malnutrition (underweight) among tuberculosis free residents was 23.37% (95% CI: 21.93-24.80). The nutritional status of tuberculosis patients were determined by site of infection AOR: 0.68[0.49-0.94], sex of the patient AOR: 0.39 [0.25-0.56], residence AOR: 3.84 [2.74-5.54], intestinal parasite infection AOR: 7 [5.2-9.95], alcohol use disorder AOR: 1.52 [1.17-2.13]. Conclusion High proportion of tuberculosis patients was malnourished. Tuberculosis patients were highly susceptible to malnutrition and even a very distal factor for malnutrition in the community became a proximal factor for tuberculosis patients.


BMC Nutrition ◽  
2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Caroline Makamto Sobgui ◽  
Leopold Kamedjie Fezeu ◽  
Fatou Diawara ◽  
Honafing Diarra ◽  
Victor Afari-Sefa ◽  
...  

2021 ◽  
Vol 9 (1) ◽  
pp. 100
Author(s):  
Uma M. Posam ◽  
Thanmai C. Chereddy ◽  
Revanth S. Pirati ◽  
N. V. Rama Rao ◽  
Elizabeth Bandrapalli ◽  
...  

Background: Earlier many studies were conducted to assess the prevalence of anemia in adults, pregnant women, and children under 5 years of age. Despite all the reasons, there is an immense need to assess the nutrition status and prevalence of anemia in a pediatric population. Therefore, the purpose of the present study was to assess the nutritional status and prevalence of anemia in the pediatric population of age group 1-12 years.Methods: The present study was a cross-sectional study with a sample size of 100 with age group 1-12 year, was conducted in Government general hospital, Guntur. The study was carried for a period of 6 months (October to March). Data were collected by using the NACS assessment guide tool for nutritional status and tallquist hemoglobin scale was used to measure hemoglobin.Results: Age group of 1-6 years had 26% severe stunting whereas in the age group lo 7-12 years, 5% of the people had severe stunting. Age group of 1-6 yr and 7-12 years had 16% of severe wasting and 13% of severe wasting respectively. The prevalence of anemia in children had a significant impact with maternal education (p<0.05), socioeconomic status of the family (p<0.05), birth order of the child (p<0.05) and doesn’t have any significant impact with father education (p>0.05), past medical history (p>0.05).Conclusions: From our study, we conclude that moderate anemia was more noticeable than mild and severe anemia in people of rural areas in and around Guntur. Severe stunting and moderate wasting was observed more in the age group of 1-6 years of children in both sexes.


2019 ◽  
Vol 4 (1) ◽  
pp. 8-16
Author(s):  
Irpan Priyasna ◽  
Lintang Purwara Dewanti ◽  
Yulia Wahyuni

Background: The prevalence of exclusive breastfeeding among infants aged 0-6 months in 2014 was 52.3%, then the prevalence of exclusive breastfeeding among infants aged 0-6 months in DKI Jakarta in 2014 was 67.1%. The low level of exclusive breastfeeding has an effect on the inadequate nutrition intake for infants that can cause growth and development disorder. This study was conducted to determine the association between breastfeeding with weight gain, nutritional status and illness incidence among infants aged 1-5 months in Grogol, West Jakarta. Methods: It was cross sectional study design, the population in this study were 96 infants aged 1-5 months recorded in all Posyandu in the area of ​​Grogol, West Jakarta. The sample in this study were 47 infants selected by purposive sampling. Data were analyzed with chi-square and fisher exact tests. Results: The results showed that there were no association between breastfeeding with weight gain (p = 0.989), nutrition status based on weight/age (p=1.000), length/age (p=0.237), and weight/length (p=0.352). There was association between breastfeeding with illness incidence (p<0.01). Conclusion: There is significant association between breastfeeding with illness incidence among infant aged 1 – 5 months.


2019 ◽  
Vol 2 (1) ◽  
pp. 155-159
Author(s):  
Ang Tshering Sherpa ◽  
Neeti Singh ◽  
Puspa Babu Basnet ◽  
Mingmar Chhiring Sherpa

Introduction: Around 25% of the total population in Nepal is adolescents (10 to 19 years old). Nutritional programs in Nepal are targeted to young children and pregnant women but neglected among adolescent. Such approach may result poor nutritional status among them. This will lead to poor health outcome and poor academic performance among school children. Thus we aimed to study the nutritional status assessment of adolescent school children in Solukhumbu.Material and Methods: It was a cross sectional study conducted over a period of two and half months (May-July 2018) in a government school at Salleri, Solukhumbu, Nepal. Study participants are 192 students, both male and female, from the age group 10 to 17 years old. Body Mass Index and Height for age was determined by anthropometry. The interview was done by using structured questionnaires to elicit socio-demographic variables.Results: Among 192 students age 10-17 years old, 122(63.5%) were female and 70(36.5%) were male. The majority was Janajati 160(83.3%), Major religion was Hindu 99(51.6%) and Buddhist 93(43.2%), Agriculture was the major occupation of both parents. The literacy rate of the father is 63.2% and mother is 39.9 percent. The majority are underweight 53(27.6%), overweight 11 (5.7%) and obese 3(1.6%). Median Height for Age was 94 (±6.5) with a minimum of 76 and a maximum of 112 and 99(51.6%) are stunted.Conclusions: Stunting, underweight and overweight were prevalent among adolescent children in the school. The causes of these problems should be identified by doing further research and intervention should be done accordingly.


2019 ◽  
Author(s):  
Berhanu Elfu Feleke ◽  
Teferi Elfu Feleke ◽  
Fantahun Biadglegne

Abstract Background Each year, more than 13.7 million people became an active case of tuberculosis and more than 1.5 million cases of tuberculosis patient will die. The association between tuberculosis and malnutrition is bi-directional, tuberculosis leads the patient to malnutrition, and malnutrition increases the risk of developing active tuberculosis by 6 to 10 times higher. Improving the nutrition of individual greatly reduces tuberculosis. The objectives of this study were to assess the nutritional status and determinants of tuberculosis patients. Methods A comparative cross-sectional study design was implemented. The sample size was calculated using Epi-info software. The data were collected from July 2015- May 2018. The data were collected by interviewing method, measuring anthropometrics indicators and collecting the stool and blood samples. The data were entered into the computer using Epi-info software and analyzed using SPSS software. Descriptive statistics were used to identify the proportion of malnutrition. Binary logistic regression was used to identify the determinants of malnutrition. Results A total of 5045 study participants were included giving the response rate of 93.1%. The prevalence of underweight among tuberculosis patients was 57.17% (95% CI: 54.80% -59.54%) and 88.52% of tuberculosis patients were anemic. The prevalence of malnutrition (underweight) among tuberculosis free residents was 23.37% (95% CI: 21.93-24.80). The nutritional status of tuberculosis patients were determined by site of infection AOR: 0.68[0.49-0.94], sex of the patient AOR: 0.39 [0.25-0.56], residence AOR: 3.84 [2.74-5.54], intestinal parasite infection AOR: 7 [5.2-9.95], alcohol use disorder AOR: 1.52 [1.17-2.13]. Conclusion High proportion of tuberculosis patients was malnourished. Tuberculosis patients were highly susceptible to malnutrition and even a very distal factor for malnutrition in the community became a proximal factor for tuberculosis patients.


2021 ◽  
pp. 73-75
Author(s):  
Nirmalya Manna ◽  
Saikat Bhattacharya ◽  
Rahul Biswas ◽  
Soumitra Mondal ◽  
V. Abinesh

Malnutrition, or under nutrition, is a frequent and often unrecognized problem in older adults. It can result in immune dysfunction; poor wound healing, anaemia, longer hospitalization and higher readmission rates, delayed recovery from surgery and a higher rate of mortality. Current statistics for the elderly in India gives a prelude to a new set of medical, social, and economic problems that could arise if a timely initiative in this direction is not taken by the program managers and policy makers. A community based observational, descriptive cross-sectional study was conducted among the elderly people residing at Banspole sub-centre area to nd out their nutritional status. Geriatric people who were the permanent resident of the study area for at least six months were included in the study. A proforma was used to collect the baseline information of the study subjects and details of factors inuencing nutrition status. Mini nutritional assessment (MNA) tool was used to assess nutritional status of 2 elderly. 300 elderly patients were included in this study with an average age of 77.29 ± 6.97 years and BMI of 23.67 ± 3.49 kg/m . Age, literacy and nancial status were found to be signicantly associated with malnutrition. Geriatric nutritional assessment should be integrated into a comprehensive geriatric assessment. Regular assessment of the nutritional status among elderly followed by early interventions will improve the health outcomes, prevents the onset of disability, improves quality of life and saves healthcare costs.


2018 ◽  
Vol 64 (5) ◽  
pp. 18-29 ◽  
Author(s):  
Ana Livia de Olieira ◽  
Ana Paula Boroni Moreira ◽  
Michele Pereira Netto ◽  
Isabel Cristina Goncalves Leite

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