One-year Effect of Wearing Orthokeratology Lenses on the Myopia Progression
Abstract Background: To Investigate the efficacy of overnight orthokeratology (Ortho-k) for myopia control and the relationship between axial length (AL) changes and different baseline factors.Methods: This is a retrospective study of 675 myopic patients (Affiliated Eye Hospital of Shandong University of TCM) who received Ortho-k correction between August 2015 and July 2017. These subjects were followed up at least for 12 months. Genders, age, parental refractive status, manifest refractions, cycloplegic refractions, uncorrected and best-corrected visual acuities, power vector of astigmatism, corneal curvature, age at initiation of Ortho-k wear (year), intraocular pressuren (IOP), anterior chamber depth (ACD), pupil size (PL), corneal diameter (CD) and AL were obtained for analysis. Correlation and multivariate logistic regression analyses were used to screen for the factors that can improve treatment outcome. Results: The baseline 675 patients’ AL of was 25.12±1.00 mm, and after 12 months of treatment, the AL was 25.30±0.94 mm, and the axial elongation was 0.18±0.22 mm. Univariate analysis of the right-eye independent variable of 675 patients showed a statistically significant association between age at initiation of Ortho-k wear, spherical equivalent refractive (SER), and changes in AL. Regression analysis results show that age at initiation of Ortho-k wear and SER are independent factors with effects on the treatment outcome.Conclusion: Ortho-k was effective in slowing myopia progression over a one-year follow-up period. Age at initiation of Ortho-k wear, and SER were found to be associated with increased change of AL during follow-up.