scholarly journals Currarino Syndrome in a China children’s health institute: on diagnosis and surgical treatment

2020 ◽  
Author(s):  
Wenbo Pang ◽  
Yajun Chen ◽  
Chunhui Peng ◽  
Kai Wang ◽  
Xiang Qi ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Operative Treatment ◽  
Multidisciplinary Approach ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Bowel Function ◽  
Currarino Syndrome ◽  
Clinical Signs And Symptoms ◽  
Prompt Diagnosis

Abstract Background Currarino syndrome is a rare disease which needs multidisciplinary management. Misdiagnosis with mal-management is common in children. This study was to summarize the clinical features of children diagnosed with Currarino syndrome in a China institute, with an emphasis on diagnosis and surgical treatment, in order to aid in the diagnosis and determination of the optimal operative treatment. Results From 2016 to 2018, seven patients were diagnosed with Currarino syndrome in our department. One patient was male and six were female, with an admission age of 27.00(16.00, 44.00) months. In four patients, diagnosis of the presacral masses had been missed. Ultrasonography, plain sacral radiographs, contrast enemas and magnetic resonance imaging are necessary for the prompt diagnosis of this syndrome. The initial treatment involved a sagittal anorectoplasty and resection of the mass, followed by a defunctioning ostomy and closure of the stoma in a staged multidisciplinary approach. A limited sagittal route was chosen for the surgical treatment in this group. After closure of the ileostomy or colostomy, bowel function was satisfactory in all children. Conclusion Improved knowledge of the different clinical signs and symptoms of Currarino syndrome will result in appropriate imaging and prompt diagnosis. A protocol with rational timing of multidisciplinary surgical procedures may help to avoid undesirable outcomes. The limited sagittal route is available for effective operative treatment.

scholarly journals Appendicitis in puerpeium: Case report

2011 ◽  
Vol 58 (4) ◽  
pp. 111-112 ◽  
Author(s):  
Milica Berisavac ◽  
Biljana Kastratovic-Kotlica ◽  
V. Tosic ◽  
N. Markovic ◽  
S. Ljustina ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Early Detection ◽  
Acute Appendicitis ◽  
Abdominal Wall ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Laboratory Infection ◽  
Infection Parameters ◽  
Clinical Signs And Symptoms

Acute appendicitis in puerperium is often diagnosed too late, because clinical signs can be unrelaible. Abdominal wall rigidity is rarely noticed in puerpeium because of weak abdominal wall muscles, laboratory parameters are not enough relaible and atipycal appendix presentation makes difficulties in diagnosis3,4. Knowing clinical signs and symptoms of appendicitis, possible complications and their early detection, make a chance for a good surgical outcome. Measuring of axillar and rectal temperature can take confusion in, and prolong time until surgical treatment. Leucocytosis in puerperium is not valid for diagnosis. We report a case of patient in puerperium with high laboratory infection parameters. Diagnosis of appendicitis is made based on clinical signs and symptoms, that is proved intraoperatively and histologicaly. Appendectomy without perforation carries less risks for mother and fetus.

scholarly journals Cervical spondylotic myelopathy: surgical decision making

1996 ◽  
Vol 1 (6) ◽  
pp. E3 ◽  
Author(s):  
Sait Naderi ◽  
Edward C. Benzel ◽  
Nevan G. Baldwin
Keyword(s):  
Decision Making ◽  
Surgical Treatment ◽  
Surgical Approach ◽  
Cervical Spondylotic Myelopathy ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Controversial Issue ◽  
Surgical Decision ◽  
Clinical Signs And Symptoms ◽  
Surgical Decision Making

Cervical spondylotic myelopathy can produce a variety of clinical signs and symptoms secondary to neural compromise and biomechanical involvement of the spine. The surgical treatment of cervical spondylotic myelopathy remains a controversial issue after many years of study, evolution, and refinement. Several ventral, dorsal, or combined approaches have been defined. The complications associated with ventral approaches and the concerns about kyphosis following dorsal approaches led to the development of a variety of laminoplasty procedures. This paper reviews the biomechanical basis of cervical spondylotic myelopathy and its effect on choosing the appropriate surgical approach.

scholarly journals Carpel ligament release for carpel tunnel syndrome (CTS) under local anesthesia: our experience with 277 cases

2019 ◽  
Vol 16 (2) ◽  
pp. 3-7
Author(s):  
Aashish Basnet ◽  
Maya Bhattachan ◽  
Sumit Joshi ◽  
Pawan Bhandari ◽  
Ram Chandra Shrestha ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Surgical Treatment ◽  
Median Nerve ◽  
Local Anesthesia ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Surgical Decompression ◽  
Tunnel Syndrome ◽  
The Common ◽  
Clinical Signs And Symptoms

Carpel tunnel syndrome (CTS) is one of the common neurological condition where median nerve is compressed by transverse carpel ligament at wrist. About 5% of general population suffer from this problem and most commonly occurred in young and middle-aged women. 30% of patients suffering from CTS can be managed by medications and physiotherapy and 70% may require surgical decompression at some stage. Surgical treatment is to decompress median nerve by releasing transverse carpel ligament either by open or endoscopic procedure. Both procedures have shown similar results. This is a retrospective study of 277 patients who underwent 349 decompressive surgical procedures under local anesthesia for CTS between May 2007 and April 2017 in our institute. Diagnosis was made from clinical signs and symptoms and confirmed by either NCV or EMG. All patients were operated in day care basis. Data were retrieved from OPD and OT records. Followed up duration ranged from 6 months to 10 years. There were 257 female and 20 male. 74% had unilateral and 26% had bilateral CTS. 93% CTS were idiopathic. 10% suffered postoperative complications.26% achieved immediate pain relief after decompression, 73% after three weeks and 98.5% after three months. Open decompression of CTS is a quick and simple OPD based surgical procedure.

scholarly journals Determination of Clinical Signs and Symptoms Predicting No Pelvic Fracture in Patients with Multiple Trauma

2018 ◽  
Vol 7 (1) ◽  
pp. 112 ◽  
Author(s):  
Hosein Kafi Kang ◽  
Saeed Majidinejad ◽  
Farhad Heidari ◽  
Keyhan Golshani
Keyword(s):  
Multiple Trauma ◽  
Pelvic Fracture ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Clinical Signs And Symptoms

scholarly journals On the Use of Hair Analysis for Assessing Arsenic Intoxication

2019 ◽  
Vol 16 (6) ◽  
pp. 977 ◽  
Author(s):  
Sidney A. Katz
Keyword(s):  
Screening Tool ◽  
Hair Analysis ◽  
Scalp Hair ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Dimethylarsinic Acid ◽  
Monomethylarsonic Acid ◽  
Clinical Signs And Symptoms ◽  
Arsenic Metabolites

Correlations between the concentrations of arsenic in scalp hair and in drinking water as well as in blood and/or urine have been reported. These correlations clearly show exposure–absorption–excretion relationships. In addition, arsenic metabolites such as monomethylarsonic acid and dimethylarsinic acid have been identified and quantified in these tissues and fluids, leaving little doubt that elevated levels of arsenic in the hair can reflect systemic arsenic intoxication. Consequently, hair analysis has potential merit as a screening procedure for poisoning by arsenic. However, questions regarding the exogenous versus the endogenous deposition of arsenic in the hair, and uncertainties about the normal level of arsenic in the hair remain unresolved. Pending their resolution, the determination of arsenic in hair should remain a screening tool, and clinical signs and symptoms should be employed to complete the diagnosis of arsenic poisoning.

scholarly journals Dementia and Major Neurocognitive Disorders: Some Lessons Learned One Century after the first Alois Alzheimer’s Clinical Notes

Geriatrics ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 5
Author(s):  
Donatella Rita Petretto ◽  
Gian Pietro Carrogu ◽  
Luca Gaviano ◽  
Lorenzo Pili ◽  
Roberto Pili
Keyword(s):  
Young Woman ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Neurocognitive Disorders ◽  
Lessons Learned ◽  
Alzheimer Dementia ◽  
Clinical Notes ◽  
Alois Alzheimer ◽  
Clinical Signs And Symptoms

Over 100 years ago, Alois Alzheimer presented the clinical signs and symptoms of what has been later called “Alzheimer Dementia” in a young woman whose name was Augustine Deter [...]

scholarly journals Nutritional Optic Neuropathies: State of the Art and Emerging Evidences

Nutrients ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2653
Author(s):  
Matilde Roda ◽  
Natalie di Geronimo ◽  
Marco Pellegrini ◽  
Costantino Schiavi
Keyword(s):  
Bariatric Surgery ◽  
Optic Neuropathy ◽  
Multidisciplinary Approach ◽  
State Of The Art ◽  
Signs And Symptoms ◽  
Therapeutic Strategies ◽  
Scientific Interest ◽  
Optic Nerve Atrophy ◽  
Prompt Diagnosis

Nutritional optic neuropathy is a cause of bilateral, symmetrical, and progressive visual impairment with loss of central visual acuity and contrast sensitivity, dyschromatopsia, and a central or centrocecal scotoma. The clinical features are not pathognomonic, since hereditary and toxic forms share similar signs and symptoms. It is becoming increasingly common due to the widespread of bariatric surgery and strict vegetarian or vegan diets, so even the scientific interest has recently increased. In particular, recent studies have focused on possible pathogenetic mechanisms, and on novel diagnostic and therapeutic strategies in order to prevent the onset, make a prompt diagnosis and an accurate nutritional supplementation, and to avoid irreversible optic nerve atrophy. Nowadays, there is clear evidence of the role of cobalamin, folic acid, thiamine, and copper, whereas further studies are needed to define the role of niacin, riboflavin, and pyridoxine. This review aims to summarize the etiology, diagnosis, and treatment of nutritional optic neuropathy, and it is addressed not only to ophthalmologists, but to all physicians who could come in contact with a patient with a possible nutritional optic neuropathy, being a fundamental multidisciplinary approach.

scholarly journals Correction to: Levoketoconazole improves clinical signs and symptoms and patient-reported outcomes in patients with Cushing’s syndrome

Pituitary ◽  
2020 ◽  
Author(s):  
Eliza B. Geer ◽  
Roberto Salvatori ◽  
Atanaska Elenkova ◽  
Maria Fleseriu ◽  
Rosario Pivonello ◽  
...  
Keyword(s):  
Cushing’S Syndrome ◽  
Patient Reported Outcomes ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Cushing's Syndrome ◽  
Original Version ◽  
Patient Reported ◽  
Author Group ◽  
Clinical Signs And Symptoms

The original version of the article unfortunately contained an error in the first name and the surname of one of the authors in the author group. The last author name was incorrectly published as ‘F. Pecori Giraldi’ and the corrected name is ‘Francesca Pecori Giraldi’ (First name: Francesca; Surname: Pecori Giraldi).

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