scholarly journals Health Utility Measurement with Index Scores for People Living with HIV/AIDS Under Combined Antiretroviral Therapy: A Comparison of EQ-5D-5L and SF-6D

2021 ◽  
Author(s):  
Xiaowen Wang ◽  
Hongbing Luo ◽  
Enlong Yao ◽  
Renhai Tang ◽  
Wenbing Dong ◽  
...  
Keyword(s):  
Social Support ◽  
Effect Size ◽  
Intraclass Correlation ◽  
Health Utility ◽  
Anxiety And Depression ◽  
Sample Population ◽  
People Living With Hiv ◽  
Convenience Sample ◽  
Living With Hiv ◽  
Hiv Aids

Abstract BackgroundThe EQ-5D-5L and SF-6D are two widely used generic index score measures. We compared the discriminative validity, agreement and sensitivity of EQ-5D-5L and SF-6D utility scores in people living with HIV/AIDS (PLWHIV).MethodsWe conducted a cross-sectional survey among PLWHIV aged more than 18 years old in 9 municipalities in Yunnan Province, China. A convenience sample was enrolled. We administered the SF-12 and EQ-5D-5L to measure health-related quality of life (QALY). The utility index of the SF-6D was derived from the SF-12. The covariate data included demographic components, clinical components and social-psychology components. To evaluate the homogeneity of the EQ-5D-5L and SF-6D, intraclass correlation coefficients (ICCs), scatter plots and Bland-Altman plots were computed and drawn. To evaluate the capacity to discriminate between different categories of clinical components, social support and anxiety and depression status, mean and median scores were calculated and compared using one-way ANOVA and the Kruskal-Wallis test, respectively. The effect size was defined as the difference of each of the characteristics and was computed using Z/N. We also used receiver operating characteristic (ROC) curves to compare the discriminative properties and sensitivity of the econometric index.ResultsA total of 1,797 respondents, with a mean age of 45.6±11.7 years (range 18 to 80), was interviewed. The distribution of EQ-5D-5L scores skewed towards full health with a skewness of -3.316. The distribution of SF-6D scores was almost centered around its mean, and the skewness was 0.084. The effect size was smaller for the EQ-5D-5L than for the SF-6D across the social support, anxiety and depression subgroups. The overall correlation between EQ-5D-5L and SF-6D index scores was 0.46 (P<0.001). An ICC of 0.59 between the EQ-5D-5L and SF-6D meant a moderate correlation and indicated general agreement. The Bland-Altman plot displayed the same results as the scatter plot. The ROC curve showed that the AUC for the SF-6D was 0.776 (95% CI: 0.757, 0.796) and that for the EQ-5D-5L was 0.732 (95% CI: 0.712, 0.752) by the PCS-12, and it was 0.782 (95% CI: 0.763, 0.802) for the SF-6D and 0.690 (95% CI: 0.669, 0.711) for the EQ-5D-5L by the MCS-12.DiscussionOur study demonstrated evidence of the performance of EQ-5D-5L and SF-6D index scores to measure health utility in people living with HIV/AIDS. Both have shown discriminative capacity and validity in measuring health status. However, there were significant differences in their performance. Users need to pay more attention to the characteristics of the target population. HIV/AIDS has transformed from being a terminal illness to being a chronic disease. We preferred to apply the SF-6D to measure the health utility of PLWHIV during the cART period.Conclusion our study has demonstrated evidence for instrument choice and preference measurements in PLWHIV under cART. The differences between the measures could generate different health utilities for the same sample population, which is critical for cost-utility analyses that guide resource allocation and decision making.

Social Support and Quality of Life Among People Living With HIV/AIDS (PLWHA) in Ghana

2021 ◽  
pp. 0192513X2110300
Author(s):  
Charles MS. Birore ◽  
Liyun Wu ◽  
Tina Abrefa-Gyan ◽  
Marilyn W. Lewis
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
People Living With Hiv ◽  
Middle Income ◽  
Middle Income Countries ◽  
Living With Hiv ◽  
Hiv Aids

Utilization of antiretroviral therapies (ART) prolongs life and heightens ability to engage in productive activities among people living with human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). This study implemented a 6-week long Social Care Intervention (SCI) Program in Ghana and identified protective factors associated with Quality of Life (QoL) among people living with HIV/AIDS (PLWHA). We discovered that SCI model in the form of social support associated positively with differences in the QoL among PLWHA. Logistic regression revealed that social support, especially affectionate support, was positively associated with a higher level of QoL. People who were older and healthier tended to have higher levels of QoL compared with their counterparts who were younger and sicker. These findings suggest that building social support system can serve as an empowerment approach to promote quality of life among PLWHA in low- and middle-income countries (LMICs) where resources are limited.

scholarly journals Psychosocial factors associated with adherence to treatment and quality of life in people living with HIV/AIDS in Brazil

2014 ◽  
Vol 63 (1) ◽  
pp. 8-15 ◽  
Author(s):  
Prisla Ücker Calvetti ◽  
Grazielly Rita Marques Giovelli ◽  
Gabriel José Chittó Gauer ◽  
João Feliz Duarte de Moraes
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Cross Sectional Study ◽  
People Living With Hiv ◽  
Adherence To Treatment ◽  
Cross Sectional ◽  
South Of Brazil ◽  
Living With Hiv ◽  
Hiv Aids

Objective: The objective of this article was to investigate the biopsychosocial factors that influence adherence to treatment and the quality of life of individuals who have been successfully following the HIV/AIDS treatment. Methods: It is a cross-sectional study carried out with 120 HIV positive participants in the south of Brazil. Among the variables studied, of note are: perceived stress, social support, symptoms of anxiety and depression and quality of life. Results: The results show that a moderate to high adherence to the treatment paired with a strong sense of social support indicate a higher quality of life. Conclusion: The combination of social support and antiretroviral treatment have an impact on physical conditions, improving immune response and quality of life.

scholarly journals Stigma, Social Support, Illicit Drug Use, and Other Predictors of Anxiety and Depression Among HIV/AIDS Patients in Pakistan: A Cross-Sectional Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Ali Ahmed ◽  
Muhammad Saqlain ◽  
Malik Muhammad Umair ◽  
Furqan Khurshid Hashmi ◽  
Hamid Saeed ◽  
...  
Keyword(s):  
Mental Health ◽  
Social Support ◽  
Illicit Drugs ◽  
Cross Sectional Study ◽  
Anxiety And Depression ◽  
People Living With Hiv ◽  
Depression And Anxiety ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hiv Aids

Introduction: Anxiety and depression in people living with HIV/AIDS (PLWHA) can lead to non-adherence to antiretroviral therapy (ART), morbidity, and mortality. Therefore, assessing the stigma, social support, and other determinants of anxiety and depression in PLWHA are important for developing further interventions.Methods: An institution-based cross-sectional study was conducted in 505 PLWHA, approached through systematic sampling, who paid routine visits to the ART center, Pakistan Institute of Medical Sciences (PIMS), Islamabad. Data was collected by pretested validated hospital anxiety and depression scale (HADS). Version 26 of the SPSS was used to apply Logistic regression analysis to identify determinants, and the 95% confidence interval (CI) adjusted odds ratio (AOR) was calculated to assess the magnitude of the relationships.Results: In PLWHA, the prevalence of co-morbid depression and anxiety was 80%. Separately, 89.9% had depression, and 80.3% had anxiety. Use of illicit drugs [AOR = 1.87, 95% CI (1.01, 3.27)], low social support [AOR = 1.21, 95% CI (1.02, 2.25)], being male [AOR = 2.21, 95% CI (1.11, 5.49)], and HIV related stigma [AOR = 2.48, 95% CI (1.25, 6.02)] were significant predictors of depression. Having detectable viral load [AOR = 3.04, 95% CI (1.04, 8.86)], young age [AOR = 5.31, 95% CI (1.19, 29.39)], no formal education [AOR = 21.78, 95% CI (4.03, 117.62)], low [AOR = 1.70, 95% CI (1.12, 6.93)] or moderate [AOR = 2.20, 95% CI (1.79, 6.09)] social support, illicit drugs addiction [AOR = 1.17, 95% CI (1.03, 2.55)], and HIV stigma [AOR = 54.3, 95% CI (21.20, 139.32)] had a remarkable association with anxiety.Conclusions: Given the high prevalence of anxiety and depression among PLWHA, the Pakistan Ministry of Health should focus more on monitoring mental health, expanding mental health services, and developing interventions based on identified factors to treat depression and anxiety among PLWHA.

Health-related Internet use, coping, social support, and health indicators in people living with HIV/AIDS: Preliminary results from a community survey.

2003 ◽  
Vol 22 (1) ◽  
pp. 111-116 ◽  
Author(s):  
Seth C. Kalichman ◽  
Eric G. Benotsch ◽  
Lance Weinhardt ◽  
James Austin ◽  
Webster Luke ◽  
...  
Keyword(s):  
Social Support ◽  
Internet Use ◽  
Health Indicators ◽  
Community Survey ◽  
People Living With Hiv ◽  
Preliminary Results ◽  
Health Related ◽  
Living With Hiv ◽  
Hiv Aids

scholarly journals Social Support Network among People Living with HIV/AIDS in Iran

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Ameneh Setareh Forouzan ◽  
Zahra Jorjoran Shushtari ◽  
Homeira Sajjadi ◽  
Yahya Salimi ◽  
Masoumeh Dejman
Keyword(s):  
Social Support ◽  
Cross Sectional Study ◽  
Network Size ◽  
Support Network ◽  
People Living With Hiv ◽  
Social Support Network ◽  
Cross Sectional ◽  
Cd4 Cell Count ◽  
Living With Hiv ◽  
Hiv Aids

This study considers social network interactions as a potential source of support for individuals living with HIV/AIDS in Iran. This cross-sectional study was conducted on 224 people with HIV/AIDS who refer to behavioral counseling centers. Participants were randomly selected among all people with HIV/AIDS from these centers. Relatives were more reported as sources of support than nonrelatives. They were closer to participants, but there was difference between the closest type among relative and nonrelative supporters(P=0.01). Mean of functional support with considering the attainable range 0–384 was low(126.74  (SD=76.97)). Social support of participants has been found to be associated with CD4 cell count(P=0.000), sex(P=0.049), and network size(P=0.000)after adjusted for other variables in the final model. Totally, in this study, many of participants had the static social support network that contained large proportions of family and relatives. The findings contribute to the evidence for promotion of knowledge about social support network and social support of people living with HIV/AIDS.

scholarly journals Social support status and associated factors among people living with HIV/AIDS in Kunming city, China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yi Li ◽  
Xiao-Wen Zhang ◽  
Bin Liao ◽  
Jun Liang ◽  
Wen-Jie He ◽  
...  
Keyword(s):  
Social Support ◽  
Antiretroviral Therapy ◽  
Associated Factors ◽  
Support Network ◽  
People Living With Hiv ◽  
Monthly Income ◽  
Factors Associated ◽  
The Social ◽  
Living With Hiv ◽  
Hiv Aids

Abstract Background People living with HIV/AIDS not only require effective treatment for the alleviation of physical discomfort but also require social support to help them address difficulties in life and relieve their psychological anxiety and uneasiness. The social support network is of tremendous importance in helping people living with HIV/AIDS maintain good physical and mental health. This study aims to analyse the social support status among people living with HIV/AIDS in Kunming and explore associated factors. Method The Social Support Rating Scale (SSRS) was used, and a questionnaire survey was conducted using convenience sampling to select people living with HIV/AIDS from 14 counties of Kunming. It collected information on general demographic information and social support status. Univariate and multivariate linear regression models were used to explore the associated factors. Results A total of 990 valid questionnaires were completed. Data from all participants were analysed. Univariate analysis suggested that the factors associated with social support may include marital status, monthly income, and antiretroviral therapy. On the other hand, factors including monthly income and antiretroviral therapy accounted for the social support total score in the multivariate analysis. Conclusion Social support among people living with HIV/AIDS in Kunming was generally low. This study identified a number of factors associated with social support among people living with HIV/AIDS. Based on our findings, appropriate interventions should be introduced to provide social support for those living with HIV/AIDS.

Sign in / Sign up

Export Citation Format

Share Document