scholarly journals Effective Factors on Sharp Score in Patients with Rheumatoid Arthritis: A Retrospective Study

2021 ◽  
Author(s):  
Jianting Wen ◽  
Jian Liu ◽  
Xin Wang ◽  
Jie Wang
Keyword(s):  
Rheumatoid Arthritis ◽  
Logistic Regression ◽  
Multinomial Logistic Regression ◽  
Treatment Strategies ◽  
High Sensitivity ◽  
Sociodemographic Factors ◽  
Symptom Duration ◽  
Effective Factors ◽  
Sharp Score ◽  
Individual Outcomes

Abstract Background: This study aims to describe the association between Sharp Score and clincial indexes, bone metabolism indexes, Disease Activity Score (DAS28) and sociodemographic factors in rheumatoid arthritis (RA).Methods: Data were were collected from the HIS (hospital information system), a national inpatient database in China, with information on the patients hospitalized during the period from 2012 to 2019. The association between Sharp Score and effective factors were identified using multinomial logistic regression and association rule mining (ARM).Results: Three thousand eight hundred and forty patients were included: 82.66% males, 17.34% females, mean (SD) age 56.95 (12.68) years and symptom duration 3.45 (1.09) years. Spearman correlation analysis and Association rules analysis showed that there were significant positive correlations between Sharp Score and effective factors. Logistic regression analysis presented that erythrocyte sedimentation rate (ESR), high-sensitivity C-reactive protein (CRP), rheumatoid factor (RF) were risk factors of Sharp Score. In the analysis of individual outcomes, sex, age, symptom duration, DSA28 score, RF, ever drinker, radiographic grading of hands were influencents of Sharp Score.Conclusion: Sharp Score should be taken into consideration in formulating treatment strategies in RA.

scholarly journals Effective factors on Sharp Score in patients with rheumatoid arthritis: a retrospective study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jianting Wen ◽  
Jian Liu ◽  
Ling Xin ◽  
Lei Wan ◽  
Hui Jiang ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Logistic Regression ◽  
Multinomial Logistic Regression ◽  
Influence Factors ◽  
Treatment Strategies ◽  
High Sensitivity ◽  
Sociodemographic Factors ◽  
Symptom Duration ◽  
Effective Factors ◽  
Sharp Score

Abstract Background This study aims to describe the association between sharp score and clinical indexes, bone metabolism indexes, Disease Activity Score (DAS28) and sociodemographic factors in rheumatoid arthritis (RA). Methods Data were collected from the HIS (hospital information system), a national inpatient database in China, with information on the patients hospitalized during the period from 2012 to 2019. The association between sharp score and effective factors were identified using multinomial logistic regression and association rule mining (ARM). Results Three thousand eight hundred and forty patients were included: 82.66% males, 17.34% females, mean (SD) age 56.95 (12.68) years and symptom duration 3.45 (1.09) years. Spearman correlation analysis and Association rules analysis showed that there were significant positive correlations between sharp score and effective factors. Logistic regression analysis presented that erythrocyte sedimentation rate (ESR), high-sensitivity C-reactive protein (CRP), rheumatoid factor (RF) were risk factors of sharp score. In the analysis of individual outcomes, sex, age, symptom duration, DSA28 score, RF, ever drinker, and radiographic grading of hands were influence factors of sharp score. Conclusion Sharp score should be taken into consideration in formulating treatment strategies in RA.

Public knowledge, perception and communication behavior surrounding COVID-19 in Malaysia

2020 ◽  
Author(s):  
Khayriyyah Mohd Hanafiah ◽  
Chang Da Wan
Keyword(s):  
Logistic Regression ◽  
Employment Status ◽  
Multinomial Logistic Regression ◽  
Movement Control ◽  
Education Level ◽  
Public Knowledge ◽  
Communication Behavior ◽  
Positive Communication ◽  
The Face ◽  
Control Order

The COVID-19 pandemic is the first to occur in an age of hyperconnectivity. This paper presents results from an online anonymous survey conducted in Malay, English, and Chinese, during the first week of the Movement Control Order in Malaysia (n=1075), which aimed to examine public knowledge, perception and communication behavior in the Malaysian society in the face of a sudden outbreak and social distancing measures. Although the level of public knowledge, risk perception and positive communication behavior surrounding COVID-19 was high, a majority of respondents reported receiving a lot of questionable information. Multinomial logistic regression further identified that responses to different items varied significantly across respondent survey language, gender, age, education level and employment status.

Role of high sensitivity C - Reactive protein and some of heavy metals in patients with rheumatoid arthritis

2020 ◽  
Vol 23 (16) ◽  
Author(s):  
Nashwan S. Albabawaty ◽  
Ali Y. Majid ◽  
Mohammed H. Alosami ◽  
Halla G. Mahmood
Keyword(s):  
Rheumatoid Arthritis ◽  
Heavy Metals ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Reduced rank multinomial logistic regression in Markov chains with application to cognitive data

2021 ◽  
Author(s):  
Pei Wang ◽  
Erin L. Abner ◽  
David W. Fardo ◽  
Frederick A. Schmitt ◽  
Gregory A. Jicha ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Markov Chains ◽  
Multinomial Logistic Regression ◽  
Reduced Rank ◽  
Cognitive Data

scholarly journals AB0144 PREDICTIVE FACTORS OF SUSTAINED CLINICAL REMISSION IN RHEUMATOID ARTHRITIS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1099.2-1099
Author(s):  
R. Fakhfakh ◽  
N. El Amri ◽  
K. Baccouche ◽  
H. Zeglaoui ◽  
E. Bouajina
Keyword(s):  
Rheumatoid Arthritis ◽  
Predictive Factors ◽  
Clinical Remission ◽  
Power Doppler ◽  
Health Assessment ◽  
Sustained Remission ◽  
Sharp Score ◽  
Remission Criteria ◽  
Ultrasound Parameters

Background:Sustained remission (SR) is an ultimate treatment goal in the management of patients with rheumatoid arthritis (RA) (1) and is associated with better RA prognosis, reflected by the quality of life, physical function and radiographic progression (2).Objectives:To investigate the prevalence and predictors of SR in RA patients.Methods:A longitudinal prospective study of patients with RA. At the inclusion, the patients were in remission DAS28 ESR≤ 2.6 for at least 6 months. A B-mode and power doppler (PD) ultrasound of 42 joints and 20 tendons was performed. Synovial hypertrophy (SH) and tenosynovitis in B-mode and PD were defined and scored from 0 to 3 using the OMERACT. The CDAI, SDAI, Boolean remission criteria, the health assessment questionnaire (HAQ) and the radiological Sharp score were calculated. Then, the DAS28 erythrocyte sedimentation rate (ESR) was evaluated at 6 and 12 months. SR was defined as the persistence of a DAS28 ESR≤2.6 at 6 or 12 months without any change in RA therapy during the follow-up. Unstable remission (UR) was defined either as DAS28 ESR > 2.6 at 6 or 12 months or an increase in RA therapy because of a relapse during the follow-up.Results:At baseline, thirty-seven patients were included. At 6 and 12 months, 28 and 24 patients completed follow-up, respectively. In decreasing order, Boolean remission (92.2%), DAS28ESRremission (85.7%), SDAI remission (85%) and CDAI remission (83.3%) achieved SR at 6 months. At 12 months, SR was found in 100% in Boolean remission, 87.5% in SDAI remission, 86.7% in CDAI remission and in 79.7% in DAS28 ESR remission. At 6 months, only the ESR (17mm/1h in SR versus 32 mm/1h in UR, p=0.04) was associated with SR. The disease duration, remission duration, swollen and tender joints, DAS28ESR, HAQ, rheumatoid factor, radiological Sharp score and ultrasound parameters weren’t associated with SR. At 12 months, the squeeze test (15% in SR vs 80% in UR, P=0.01), the ESR (15 mm/1h in SR versus 30 mm/1h in UR, p=0.03), the Boolean remission (61.1% in SR versus 0% in UR, p=0.04) and the DAS28ESR (mean: 1.8 in SR versus 2.5 in UR, P=0.01) were associated with SR. However, no association was found with radiological Sharp score and ultrasound parameters. On multivariate analysis, the ESR (OR=1.13, CI95%=1.01-1.2, p=0.03) and the Squeeze test (OR=21.3, CI95%=1.7-263, p=0.01) were predictors of SR, at 12 months.Conclusion:At 6 and 12 months, 79.7%-85.7% of patients in DAS28 ESR remission achieved sustained remission, respectively. Boolean and DAS28 ESR remission were associated with SR. Unlike DAS28 ESR, Boolean remission seems to reflect more the SR. The squeeze test and the ESR were predictors’ factor. However, the radiological and the ultrasound parameters didn’t show any association.References:[1]Ajeganova S, Huizinga T. Sustained remission in rheumatoid arthritis: latest evidence and clinical considerations. Ther Adv Musculoskelet Dis. 2017;9(10):249-62.[2]Xie W, Li J, Zhang X, Sun X, Zhang Z. Sustained clinical remission of rheumatoid arthritis and its predictive factors in an unselected adult Chinese population from 2009 to 2018. Int J Rheum Dis. 2019;22(9):1670-8.Disclosure of Interests:None declared

scholarly journals Association between Social Integration and Face Mask Use Behavior during the SARS-CoV-2 Pandemic in Japan: Results from U-CORONA Study

2021 ◽  
Vol 18 (9) ◽  
pp. 4717
Author(s):  
Nobutoshi Nawa ◽  
Yui Yamaoka ◽  
Yuna Koyama ◽  
Hisaaki Nishimura ◽  
Shiro Sonoda ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Social Network ◽  
Social Integration ◽  
Response Bias ◽  
Multinomial Logistic Regression ◽  
Face Mask ◽  
Neighborhood Association ◽  
Multinomial Logistic Regression Analysis ◽  
Use Behavior

Face mask use is a critical behavior to prevent the spread of SARS-CoV-2. We aimed to evaluate the association between social integration and face mask use during the COVID-19 pandemic in a random sample of households in Utsunomiya City, Greater Tokyo, Japan. Data included 645 adults in the Utsunomiya COVID-19 seROprevalence Neighborhood Association (U-CORONA) study, which was conducted after the first wave of the pandemic, between 14 June 2020 and 5 July 2020, in Utsunomiya City. Social integration before the pandemic was assessed by counting the number of social roles, based on the Cohen’s social network index. Face mask use before and during the pandemic was assessed by questionnaire, and participants were categorized into consistent mask users, new users, and current non-users. Multinomial logistic regression analysis was used to examine the association between lower social integration score and face mask use. To account for possible differential non-response bias, non-response weights were used. Of the 645 participants, 172 (26.7%) were consistent mask users and 460 (71.3%) were new users, while 13 (2.0%) were current non-users. Lower social integration level was positively associated with non-users (RRR: 1.76, 95% CI: 1.10, 2.82). Social integration may be important to promote face mask use.

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