Comparison of two techniques for the treatment for atlantoaxial instability injury: C1–C2 transarticular screws and C1 lateral mass–C2 pedicle screws
Abstract Background: The aim was to evaluate the effectiveness and safety of transarticular C1–C2 screw fixation (C1C2-TAS) and C1 lateral mass–C2 pedicle screw fixation (C1LM-C2PS) in patients with C1–C2 instability injuries.Methods: This study was a prospective, self-controlled, single-institute study on two fixation techniques for the treatment of atlantoaxial instability caused by injury. From 06/2006 to 02/2017, 118 patients were allocated into two groups: group 1 (C1C2-TAS group) with 52 patients and group 2 (C1LM-C2PS group) with 66 patients. The investigated variables were noted before, during and after surgery. All patients were closely followed up through physical examination and radiological imaging at 3 months postoperatively.Results: There were significant differences in operation time, blood loss, and hospital length-stay between the two groups (p <0.001). Compared with those in the C1LM-C2PS group, the mean operation time was shorter (78.94 vs. 110.91 min; p = 0.0003), blood loss during surgery was lower (122.31 vs. 258.33 ml; p <0.0001) and hospital length-stay was shorter (5.31 vs. 8.34 days; p = 0.0003) in the C1C2–TAS group. The complication of surgery was low with no injury of vertebral artery. After surgery, clinical presentations were significantly reduced and were statistically significant in both groups. The remaining patients showed satisfactory internal fixation in the postoperative radiographs and CT examination.Conclusion: C1C2-TAS and C1LM-C2PS demonstrated effectiveness and safety in the treatment of patients with atlantoaxial instability injury. Notably, C1C2-TAS resulted in shorter surgical time, lower blood loss during surgery and shorter in-hospital stay than C1LM-C2PS.