scholarly journals Psoriasis Is Associated With Worse Quality of Life Compared With the Other 12 Skin Diseases: A Cross-sectional Study

Author(s):  
Li Zhou ◽  
Wenwei Ouyang ◽  
Zehuai Wen ◽  
Chuanjian Lu ◽  
Zehui He

Abstract Background: Skin diseases impair patients’ quality of life (QoL). Psoriasis is of particular concern because it affects multiple facets of patients’ lives.Objective: The aim of this study was to investigate whether having psoriasis was associated with the more severe QoL impairment compared with the other 12 skin diseases, based on the Dermatology Life Quality Index (DLQI).Methods: This multicenter observational cross-sectional study was conducted in 9centers in China. Socio-demographic variables and health history were collected with a standardized form questionnaire. QoL was measured by the DLQI. DLQI scores were compared between patients with psoriasis and without psoriasis using univariate analysis. Then multivariate linear regression was used to related QoL to groups (psoriasis vs. non psoriasis), clinical and socio-demographic characteristics.Results: Of 8,339 included dermatological participants, 1,310 (15.7%) had psoriasis, and 7,029 (84.3%) did not. The QoL of patients with psoriasis was lower than that of patients without psoriasis based on the DLQI score (11.20 ± 7.37 vs 8.12 ± 6.26, P < 0.05). The results of multivariate linear regression indicated the same results when adjusting clinical and socio-demographic characteristics.Conclusion: Patients with psoriasis experience more quality of life impairment than patients without psoriasis. More attention should be paid to patients with psoriasis in dermatological health policy decision.

Author(s):  
Sau Huu Nguyen ◽  
Long Hoang Nguyen ◽  
Giang Thu Vu ◽  
Cuong Tat Nguyen ◽  
Thu Hoai Thi Le ◽  
...  

Skin diseases have caused a heavy burden on the infected population worldwide. This study aimed to examine the health-related quality of life (HRQOL) among patients with different skin diseases and identify associated factors. A cross-sectional study with 430 participants was conducted at the Vietnam National Hospital of Dermatology and Venereology (NHD) from September to November 2018. The EuroQol-5 Dimensions-5 Levels (EQ-5D-5L) instrument was employed, which measures the EQ-5D index from five domains including mobility, self-care, usual activity, pain/discomfort, and anxiety/depression. Multivariate Tobit regression was adopted to determine factors that were associated with HRQOL (EQ-5D index). The rate of atopic dermatitis was the highest with 28.8%, following by contact dermatitis (17.0%) and skin fungal infections (13.0%). Regarding HRQOL, anxiety/depression was the most common health problem in patients with skin diseases (71.8%), following by pain/discomfort (63.6%). The mean EQ-5D index score was 0.73 (SD = 0.19). The lowest EQ-5D index scores were obtained for females with skin infections (mean = 0.52) and for males with psoriasis (mean = 0.59). Females had significantly lower scores compared to males (Coef. = −0.06; 95% CI = −0.11 to −0.01). Higher income and living in rural areas were also negatively correlated with the EQ-5D index. This study demonstrated the low HRQOL among patients with skin diseases in Vietnam and emphasized the vulnerability of patients with different socioeconomic statuses to their HRQOL.


2021 ◽  
Vol 40 (1) ◽  
Author(s):  
Eba’a Hafi ◽  
Ro’ya Soradi ◽  
Sarah Diab ◽  
Ahmad M. Samara ◽  
Marah Shakhshir ◽  
...  

Abstract Background End-stage renal disease (ESRD) is a leading cause of death and morbidity worldwide. Malnutrition is a common problem among hemodialysis (HD) patients that negatively impacts their prognosis and is linked to an increase in morbidity and mortality in these patients, as well as a decrease in their quality of life (QOL). In this study, we aimed to evaluate the QOL and to investigate factors that can influence it, including nutritional status, as well as socio-demographic factors, among Palestinian diabetic patients on HD therapy. Methods This was a cross-sectional study that occurred at a large hemodialysis center in Palestine. Malnutrition was assessed by the malnutrition-inflammation scale (MIS), and the quality of life was evaluated by using the EuroQoL five-dimensional instrument (EQ-5D). Multivariable linear regression analysis was carried out to look at the effect of multiple variables on QOL. Results A total of 118 diabetic patients on HD were included. Of these, 66.9% were male, and 60.2% were aged 60 years or higher. Having multiple comorbid diseases (p=0.004) and having been on HD for >4 years (p=0.003) were significantly associated with a higher MIS score, whereas living alone (p=0.037) and having been on HD for >4 years (p=0.002) was significantly associated with lower EQ-5D score. We also observed a significant association between the MIS score and the EQ-5D score(r=−0.616, p<0.001). Multiple linear regression analysis demonstrated that diabetic hemodialysis patients who lived within a family household were positively correlated with the QOL score (standardized coefficient, 0.178; 95% confidence interval (CI), 0.042 to 0.372; p = 0.015), and MIS score was significantly and negatively correlated with QOL scores (standardized coefficient, −0.587; 95% CI, −0.047 to −0.028; p < 0.001). Conclusions We found that malnutrition was associated with a lower QOL score among diabetic patients on HD. We recommend general practitioners, dietitians, nephrologists, and nurses to make plans that pay more attention to this group of patients who show evidence of malnutrition. Patients on dialysis for ≥ 4 years, patients who live alone, and those suffering from multiple co-morbid diseases should receive special care due to their higher risk of being impacted by this problem.


2020 ◽  
Author(s):  
Nasim Ghodoosi ◽  
Hana Arghavani ◽  
Atieh Mirzababaei ◽  
Mir Saeed Yekaninejad ◽  
Seyed Ali Keshavarz ◽  
...  

Abstract Objective: The objective of this study was to investigate associations between Energy-Adjusted Dietary Inflammatory Index (EDII) with quality of life and serum inflammatory markers.Results: This cross-sectional study was performed on 280 adult healthy overweigh and obese aged between 18 and 50 years old that was selected from 20 various health centers by a multistage cluster random sampling method. The mean age of the study participants was 36.30±8.05 years. Analyses were performed using multivariable linear regression, adjusting for age, weight, physical activity, smoking status, economic status, and employment status. Linear regression analysis demonstrated that E-DII were significantly associated with certain the quality of life criteria, such as physical function, mental health, and vitality (β = 5.58, 95% CI 0.72, 10.43, p = 0.024, β = 16.88, 95% CI 10.75, 23, p < 0.0001 and β = 14.29, 95% CI 9.48, 20.36, p < 0.0001, respectively). No significant associations were observed between EDII and serum level hs-CRP. It was found that dietary inflammatory potential decreased some quality of life measurements and levels in overweight and obese Iranian women.


2020 ◽  
Author(s):  
Nasim Ghodoosi ◽  
Hana Arghavani ◽  
Atieh Mirzababaei ◽  
Mir Saeed Yekaninejad ◽  
Seyed Ali Keshavarz ◽  
...  

Abstract Objective: The objective of this study was to investigate associations between Energy-Adjusted Dietary Inflammatory Index (EDII) with quality of life and serum inflammatory markers.Results: This cross-sectional study was performed on 280 adults healthy overweight and obese aged between 18 and 50 years old that was selected from 20 various health centers by a multistage cluster random sampling method. The mean age of the study participants was 36.30±8.05 years. Analyses were performed using multivariable linear regression, adjusting for age, weight, physical activity, smoking status, economic status, and employment status. Linear regression analysis demonstrated that E-DII were significantly associated with certain the quality of life criteria, such as physical function, mental health, and vitality (β = 5.58, 95% CI 0.72, 10.43, p = 0.024, β = 16.88, 95% CI 10.75, 23, p < 0.0001 and β = 14.29, 95% CI 9.48, 20.36, p < 0.0001, respectively). No significant associations were observed between EDII and serum level hs-CRP. It was found that dietary inflammatory potential decreased some quality of life measurements and levels in overweight and obese Iranian women.


2019 ◽  
pp. 55-62
Author(s):  
Vuong Diem Khanh Doan ◽  
Ngoc Minh Chau Ho ◽  
Thi Van Ngo ◽  
Thi Bao Nga Phan ◽  
Thi Hong Phan Nguyen

Background: Vietnam is entering the stage of aging population; as a result, the quality of life (QOL) of the elderly is really a matter of concern. There is a great deal of research on the quality of life of the elderly while Vietnam witnesses a lack of research on this topic, especially on how physical and social activities have impact on QOL of the elderly. Objectives: (1) To describe the situation of participation in physical, social activities and QOL of the elderly residing in Truong An Ward, Hue city. (2) To examine the association between physical, social activities and QOL among participants. Methodology: This study used cross-sectional study design. A total sample of 420 people aged 60 and above in Truong An Ward, Hue city were interviewd. The SF36 was used to measure the QOL of participants. Results: Percentage of the elderly taking part in physical activity were 66%. 49% reported having the habit of taking part in social activities. The majority of the elderly get their QOL level in three health fields, namely physical, mental and general health at above average. (56.0, 60.7 and 60.8 respectively). There were significant associations between physical activities, social activities and QOL among participants. Conclusion: The percentage of the elderly taking part in physical and social activities were still low. Besides, QOL of the elderly at the research location was not really high. It’s important to encourage the elderly taking part in physical and social activities to improve their quality of life. Key words: Physical activities, social activities, QOL, the elderly


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