scholarly journals Metastatic hepatocellular carcinoma to the parotid gland Associated with multiple metastasis: Case report

2020 ◽  
Author(s):  
Mingxia Sun ◽  
Shundong Cang

Abstract Introduction: The incidence of liver cancer is very high in China, and it is more common in patients with a history of hepatitis B.Most patients with liver cancer have distant metastasis at the time of visiting, but parotid metastasis is very rare. We report a patient with parotid enlargement who was diagnosed with multiple metastasis of liver cancer. Presentation of Case: A 52-year-old male presented with parotid enlargement for one month.after the right deep maxillofacial neck mass was cut and biopsied,Metastatic hepatocellular carcinoma of the parotid gland associated with multiple metastasis was diagnosed. Discussion: Metastasis of liver cancer to the parotid gland is very rare, to date, only 7 cases HCC metastasis to the parotid gland have been reported, this case is the first report in China. For patients with parotid enlargement at the first diagnosis, no history of hepatitis or liver cancer, and normal or slightly elevated AFP,It is very easy to misdiagnose and miss diagnosis.Pathological diagnosis and complete systemic examination are very important in the diagnosis of tumor.Although very rare, parotid metastases in HCC should be maintained with high suspicion.

2018 ◽  
Vol 37 (1) ◽  
pp. 39-42
Author(s):  
Md Mozammel Haque ◽  
Kamrunnaher Shultana ◽  
Syeda Afroza

This case is being reported because tubercular involvement of the parotid gland in the pediatric population is extremely rare even in the TB endemic country like Bangladesh. Here, a case of an 11 year old girl with tuberculous abscess of the right parotid gland is reported who presented with right sided earache, headache and fever for two months followed by development of a swelling in front of the right ear for one and half months. There was no history of running nose, drooling of saliva, pain on deglutition, prolonged cough or hemoptysis, loss of appetite or weight loss. Patient came from an area where many known TB patients reside. General and systemic examination revealed no abnormality except the swelling. Her BCG mark was present and BMI was age appropriate. Tuberculin test (MT) was positive and chest x-ray revealed no abnormality. The diagnosis of tuberculous parotid abscess was initially made by histopathology of the swelling. Treatment was commenced with a six months anti-TB regimen according to the national TB guideline. Finally, TB was confirmed upon the clinical response to anti-TB therapy. Therefore, it is recommended to consider TB in the differential diagnosis of parotiditis and chronic swelling of this salivary gland especially in TB endemic countries. J Bangladesh Coll Phys Surg 2019; 37(1): 39-42  


2020 ◽  
Vol 8 (2) ◽  
pp. e001012
Author(s):  
Luis Pedro Rocha Moreira ◽  
Emma Scurrell ◽  
Paul Mahoney ◽  
Stephen Baines

Canine thyroid tumours are uncommon and the majority of tumours are carcinomas or adenomas, with only very few mixed tumours or metastases from distant sites described to date. A primary thyroid haemangiosarcoma has never been reported in veterinary medicine. In this case report, we describe a dog with a history of a large, non-painful, mobile ventral neck mass in the right paralaryngeal region. CT and ultrasound-guided fine needle aspirates were used for clinical staging. The mass was surgically excised and histopathological examination indicated a haemangiosarcoma. Abdominal ultrasound revealed the presence of splenic nodules and splenectomy indicated the presence of haemangiosarcoma. Chemotherapy with doxorubicin was started, but the dog was euthanased after three rounds of therapy, 97 days after the mass was discovered.


2003 ◽  
Vol 20 (4) ◽  
pp. 387-388 ◽  
Author(s):  
Ioannis Vlasseros ◽  
Efstratios Tapanlis ◽  
Andreas Katsaros ◽  
Dimitrios Kountouras ◽  
Ioannis Gialafos

2020 ◽  
Vol 13 (12) ◽  
pp. e238469
Author(s):  
Alexandra G Britten ◽  
Payam Entezami ◽  
Brent A Chang

A 30-year-old woman was referred to the ear, nose and throat clinic by her primary care physician for a 10-year history of an asymptomatic, large, right-sided neck mass. On examination, the patient had a palpable, non-tender, five-by-four centimetre, mobile, right-sided level II neck mass. CT scan with intravenous contrast showed an enhancing mass with multiple fluid cavities, splaying the external carotid and internal carotid arteries, concerning for a carotid body tumour. Patient was then referred to interventional radiology for angiography and embolisation prior to definitive surgical excision. However, when the mass was then excised surgically, final pathology identified the mass as a ganglioneuroma. Patient recovered well postoperatively with some ptosis of the right eye and symptoms consistent with first bite syndrome, treated with conservative measures.


2019 ◽  
Vol 4 (3) ◽  
pp. 253-256
Author(s):  
Yousef J. Cruz-Iñigo ◽  
Stephen A.M. De Souza

Purpose: This article reports a case of presumed choroidal metastasis from an oncocytic carcinoma of the parotid gland. Methods: A 70-year-old man with history of an oncocytic carcinoma of the parotid gland presented owing to a 1-month history of progressive blurred central vision shortly after metastatic surveillance workup revealed liver, lung, and spine metastases. Fundus examination of the right eye showed a yellow choroidal mass surrounding the optic nerve and extending inferonasally, which is associated with subretinal fluid involving the foveal center. A-scan and B-scan ultrasonography were remarkable for a dome-shaped choroidal mass with medium-to-high internal reflectivity. Fluorescein angiography revealed pinpoint foci of hyperfluorescence over the choroidal lesion with late leakage. Magnetic resonance imaging of the brain showed evidence of metastatic disease to the cerebellum. While the patient underwent systemic chemotherapy, external beam radiotherapy was used to treat the eye. Results: Four months later, visual acuity improved, the tumor reduced in size, and the subretinal fluid resolved. Systemic workup disclosed no new metastases. Conclusion: Oncocytic carcinoma of the parotid gland is a rare and aggressive malignant neoplasm with frequent recurrences and distant metastases. The current case suggests that oncocytic carcinoma can metastasize to the choroid and, consequently, ocular metastasis surveillance is advised in these patients.


2019 ◽  
Vol 12 (10) ◽  
pp. e226494
Author(s):  
Amisha Jakharia-Shah ◽  
Hugh Wheatley ◽  
Matthew Beesley

A 59-year-old woman presented to an otolaryngology clinic with an 8-week history of a painless lump over her left parotid gland. Her medical history included an invasive ductal carcinoma (33 mm) and a ductal carcinoma in situ (70 mm) of the right breast, for which she had a mastectomy and various adjuvant therapies. The primary tumour presented 8 years prior to the metachronous metastasis. This patient was a non-smoker and had no significant family history. Post-superficial parotidectomy pathology revealed the parotid gland tumour to be oestrogen receptor-positive and HER2 receptor-positive, thus ruling out the initial differential diagnosis of a pleomorphic adenoma. A consequential total parotidectomy with a posterolateral neck dissection was performed with sparing of the facial nerve. The patient recovered well having only encountered a self-resolving salivary fistula. She portrayed no signs of facial nerve palsy and subsequent imaging scans showed no abnormalities.


2021 ◽  
Vol 15 (8) ◽  
pp. 2339-2345
Author(s):  
Shokoh Taghipour ◽  
Marzieh Ghane Ezabadi ◽  
Vahid Rakhshandeh

Objectives: Liver cancer is one of the five most common cancer and the second leading cause of cancer death in men worldwide and the seventh most common cancer and the sixth leading cause of death in women from cancers. Liver cancer was the tenth most common cancer in Yazd in 1388 to 19% in women and 26% of males that has been more prevalent than in other provincial capitals. Methods: This cross-sectional descriptive study is a census of patients with hepatocellular carcinoma who referred to Yazd hospital pathology centers. All samples that have complete data from 1390 to 1394 were enrolled in the study. Information including age, sex, method of treatment and numbers of patients collected and then analyzed using statistical software spss 16 is placed. The aim of this study was to determine the survival rate of liver cancer patients according to age, sex, treatment, race and disease risk factors. Results: Of the 48 patients, 47.9% were female and 52.1% male during the five years . the average of age in this study was 62.81years. of the patients studied was 62.81 years .93.8% of patients were Iranian race. In this study, median survival was 7.43 months. The diabetes melitus with a prevalence of 18.8% was most common among the risk factors. alcohol consumption and the prevalence of hepatitis C has the lowest prevalence that was 1.9%. 83% of patients in this study were treated but other don’t come satisfaction for any treatment. Conclusion: In this study, like other studies, the incidence of liver cancer in men was higher than women. Most were Iranian people and the relationship between race and survival was no significant relationship between age, type of treatment, such as surgery, radiotherapy or chemotherapy with survival rate was not significant. But after Cox regression between age, family history of liver cancer, diabetes and treatment with survival in patients with hepatocellular carcinoma, there was a significant relationship. Keywords: HCC, Yazd, Survival


2000 ◽  
Vol 48 (8) ◽  
pp. 516-519 ◽  
Author(s):  
Tomohiro Murakawa ◽  
Shinichi Takamoto ◽  
Masahiko Ezure ◽  
Minoru Ono ◽  
Motohiro Kawauchi ◽  
...  

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S84-S85
Author(s):  
S Ayub ◽  
Z Al-Duwal ◽  
D Sellers ◽  
A Rosenberg

Abstract Introduction/Objective Primary cutaneous follicle center lymphoma (PCFCL) is the most common primary cutaneous B-cell lymphoma. It arises from mature germinal center B lymphocytes. Here we report two cases of PCFCL with parotid gland involvement. Methods First case is a 66-year-old male with an enlarging forehead mass for nine months and a painless nodule on the right pre-auricular skin. Second is a 39-year-old male with a history of a recurring scalp spindle cell B-cell lymphoma now presenting with an enlarging lesion on the scalp and “fullness” in the right neck. There was no nodal or other extranodal involvement found in either case. Skin and parotid gland biopsies were obtained in both cases. Results Case one: The skin and parotid gland demonstrated sheets of predominantly medium sized infiltrating lymphoma cells, positive for CD20, Bcl-6, CD5 (dim) and Bcl-2 (dim), and negative for CD10, Bcl-1, and MUM-1. The epidermis was spared. Case two demonstrated medium sized, spindle shaped lymphoma cells. The skin showed a vague follicular growth pattern, sparing the epidermis. The parotid gland showed diffuse infiltration by lymphoma cells, positive for CD20 and Bcl-6, Bcl-2 (dim) and no definite positivity for CD10. Fluorescent in situ hybridization for t(14;18) translocation was absent in both cases. Conclusion Dissemination of PCFCL to extracutaneous sites is uncommon (~10% of cases) and to our knowledge, has not been reported in the parotid gland. Here we present two unique cases, which in the absence of nodal disease, prove the diagnosis of PCFCL with parotid gland involvement.


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