Comparative Study on Sensing Characteristics of Optical Surface Plasmon Resonance Sensors Using A Single LHM-Dielectric Interface: A Theoretical Study

Author(s):  
benamar bouhafs ◽  
Abdellatif CHERIFI

Abstract This work addresses a theoretical analysis on optical planar surface plasmon resonance (SPR) sensors. The proposed plasmonic system consists of an active left-handed material (LHM) stacked between a glass-prism and a sensing environment. To evaluate the limits of the surface sensitivity related to SPR excitation, two arrangements between previous media are separately investigated for comparison. Employing the transfer matrix method (TMM), angular TM-reflectance calculations and intrinsic sensing characteristics of previous arrangements, have been investigated with the impact of thicknesses and refractive index (RI) of the media involved. We found the suitable prism material RI, and the preferential arrangement between LHM and sensing environment allowing, thus the increase of the detection sensitivity of SPR excitation. The results of TM-reflectance obtained by varying the sensing environment RI, indicate the ability of the configuration to support an surface plasmon (SP) mode, with a tunable Q-factor from 72 to 748. In addition, distinct optical functionalities achieved with the proposed mono-layer LHM system exhibiting a single SPR mode, and multiple resonant oscillations, are highlighted on both the effects of RI and structure ‘thicknesses. Finally, the relationships between characteristics of TM-reflectance spectra versus the performance parameters are analytically derived.

2017 ◽  
Vol 7 (1) ◽  
pp. 1
Author(s):  
Wida Yanti ◽  
Asih Melati

<p><br />Halal foods and medicines are an absolute daily needs for the Muslim community in Indonesia. Therefore the authority institutions in indonesian goverment should ensure the availability of this. It is of course inseparable from the role of higher education through the development of its technology to develop halal detection of foods and drugs. This study is an effort to contribute to the Halal Research Center of UIN Sunan Kalijaga Yogyakarta through the biosensor development in halal detection foods and medicines based on biosensor SPR. This device using graphene materials to improve the detection sensitivity of pork gelatin material that is likely contained in foodstuffs and medicine. From analytical calculation and computation, enhancement of the SPR biosensor performance by involvement graphene it was shown through the ATR (Attenuated Total Reflectance) reflective curve. The result of this results was found the enhancement of the sensitivity 2,86 %.</p><p>Keyword: Surface Plasmon Resonance (SPR), Porcine Gelatin, Graphene, ATR</p>


Nanophotonics ◽  
2017 ◽  
Vol 6 (5) ◽  
pp. 1017-1030 ◽  
Author(s):  
Youjun Zeng ◽  
Rui Hu ◽  
Lei Wang ◽  
Dayong Gu ◽  
Jianan He ◽  
...  

AbstractSurface plasmon resonance (SPR) biosensor is a powerful tool for studying the kinetics of biomolecular interactions because they offer unique real-time and label-free measurement capabilities with high detection sensitivity. In the past two decades, SPR technology has been successfully commercialized and its performance has continuously been improved with lots of engineering efforts. In this review, we describe the recent advances in SPR technologies. The developments of SPR technologies focusing on detection speed, sensitivity, and portability are discussed in details. The incorporation of imaging techniques into SPR sensing is emphasized. In addition, our SPR imaging biosensors based on the scanning of wavelength by a solid-state tunable wavelength filter are highlighted. Finally, significant advances of the vast developments in nanotechnology-associated SPR sensing for sensitivity enhancements are also reviewed. It is hoped that this review will provide some insights for researchers who are interested in SPR sensing, and help them develop SPR sensors with better sensitivity and higher throughput.


Sensors ◽  
2020 ◽  
Vol 20 (19) ◽  
pp. 5572
Author(s):  
Georgi Dyankov ◽  
Ekaterina Borisova ◽  
Evdokia Belina ◽  
Hristo Kisov ◽  
Ivan Angelov ◽  
...  

Immobilization of proteins on a surface plasmon resonance (SPR) transducer is a delicate procedure since loss of protein bioactivity can occur upon contact with the untreated metal surface. Solution to the problem is the use of an immobilization matrix having a complex structure. However, this is at the expense of biosensor selectivity and sensitivity. It has been shown that the matrix-assisted pulsed laser evaporation (MAPLE) method has been successfully applied for direct immobilization (without a built-in matrix) of proteins, preserving their bioactivity. So far, MAPLE deposition has not been performed on a gold surface as required for SPR biosensors. In this paper we study the impact of direct immobilization of heme proteins (hemoglobin (Hb) and myoglobin (Mb)) on their bioactivity. For the purpose, Hb and Mb were directly immobilized by MAPLE technique on a SPR transducer. The bioactivity of the ligands immobilized in the above-mentioned way was assessed by SPR registration of the molecular reactions of various Hb/Mb functional groups. By SPR we studied the reaction between the beta chain of the Hb molecule and glucose, which shows the structural integrity of the immobilized Hb. A supplementary study of films deposited by FTIR and AFM was provided. The experimental facts showed that direct immobilization of an intact molecule was achieved.


Sign in / Sign up

Export Citation Format

Share Document