scholarly journals The Chinese Version of The Quality of Life in Childhood Epilepsy Questionnaire-16-C (QOLCE-16-C): Translation, Validity, and Reliability

Author(s):  
Ping Tang ◽  
Qunfeng Lu ◽  
Wenjuan Tang ◽  
Aiqiu Li ◽  
Xiaomin Sun ◽  
...  

Abstract BackgroundEpilepsy is one of the most common chronic neurological diseases that adversely impact the quality of life of patients and their families. The 16-item measure of the Quality of Life Childhood Epilepsy Questionnaire (QOLCE-16) was designed to assess health-related quality of life (HRQOL) among children with epilepsy. The purpose of the study was to translate and evaluate psychometric properties of the QOLCE-16.MethodsThe 10 steps of Principles of Good Practices for translation and cultural adaptation of measures were adopted to translate the QOLCE-16 into Chinese. After that, item analysis, internal consistency, test-retest reliabilities, content validity and construct validity were conducted to test its applicability in children with epilepsy under the culture of China.ResultsA total of 414 objects were enrolled in our study. The results of item analysis showed the QOLCE-16-C had good discrimination, and each item was significantly related to the total scale (P<0.001). The Cronbach’s α value was 0.938 and the Test-retest reliability was 0.724. For validity, results showed that the QOLCE-16-C had good content validity. Exploratory factor analysis indicated it was reasonable that the QOLCE-16-C consists of four dimensions after rotation. Confirmatory factor analysis demonstrated good validity (χ2/df = 1.698, GFI = 0.913, CFI = 0.974, RMSEA = 0.058).ConclusionThe Chinese version of QOLCE-16-C appears to be a culturally appropriate, valid and reliable tool to assess the health-related quality of life of children with epilepsy in China.

2018 ◽  
Vol 21 (2) ◽  
pp. 84-94 ◽  
Author(s):  
Cory E Noble ◽  
Lesley M Wiseman-Orr ◽  
Marian E Scott ◽  
Andrea M Nolan ◽  
Jacky Reid

Objectives The objective of this study was to develop a valid, reliable, web-based generic feline health-related quality-of-life (HRQoL) questionnaire instrument to measure the affective impact of chronic disease. Methods A large initial item pool, obtained through interviews with cat owners, was reduced using predetermined criteria, survey scores for relevance and clarity, and the ability of individual items to discriminate between healthy and sick cats when owners completed a prototype questionnaire. Using these data, factor analysis was used to derive a scoring algorithm and provide evidence for factorial validity. Validity was demonstrated further in a field trial using a ‘known groups’ approach (sick vs healthy cats will have a different HRQoL profile, and the HRQoL profile of cats will deteriorate as comorbidities increase). Test–retest reliability was assessed using intra-class correlation coefficients (ICCs). Results In total, 165 items were reduced to 20 and, on the basis of a factor analysis that explained 72.3% of the variation in scores input by 71 owners of 30 healthy and 41 sick cats using the prototype, these were allocated to three domains (vitality, comfort and emotional wellbeing [EWB]) with a scoring algorithm derived using item loadings. Subsequently, the owners of 36 healthy and 58 sick cats completed one or two (n = 48) assessments. Median scores (healthy vs sick) for all domains were significantly different ( P <0.001), 78% of cats were correctly classified as healthy or sick and for comorbidities the correlation coefficients were moderate (vitality 0.64; comfort 0.63; EWB 0.50). Test–retest reliability was good (ICC vitality 0.635; comfort 0.716; EWB 0.853). Conclusions and relevance This study provides initial evidence for the validity and reliability of a novel HRQoL instrument to aid the assessment and management of chronic diseases of cats.


2020 ◽  
Author(s):  
Ana M. Otoya Tono ◽  
Lucía C. Pérez Herrera ◽  
Daniel Peñaranda García ◽  
Sergio Moreno López ◽  
Ricardo Sánchez Pedraza ◽  
...  

Abstract Background Evaluation of health-related quality of life (HRQoL) is considered an important aspect of clinical assessment and health research. Chronic Otitis Media (COM) is related to the quality of life deterioration subsequent to COM symptoms, social communication impairments and lower work performance. However, there is no reliable information regarding the impact of this disease on health and quality of life in many resource-poor countries. Therefore, we translated into Spanish and culturally adapted the Chronic Otitis Media Questionnaire-12 (COMQ-12) for the evaluation of Health-Related Quality of Life (HRQoL) of Chronic Otitis Media (COM) in adult patients. Also, we assessed the psychometric properties of our version of the questionnaire.Methods Two otology referral centers in Bogotá, Colombia were included. The Spanish version of COMQ-12 was applied twice to 200 adult patients with confirmed COM diagnosis and to 31 healthy controls in order to perform the validation process and assess the internal consistency of this questionnaire. Psychometric characteristics (replicability, reliability, and validity) of the COMQ-12 were assessed. Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) were conducted via structural equation modeling (SEM) in order to test the questionnaire’s structure.Results The Spanish version of the COMQ-12 showed good internal consistency (Cronbach’s Alpha=0.8526, McDonald’s Omega = 0.8901). Coefficients corresponding to Lin’s Concordance test and test-retest reliability were 0.945 and 0.82 respectively. Correlation between the Visual Analogue Scale (VAS) and the COMQ-12 was = 0.676 (IC 95% = 0.593; 0.745). Factor analysis of the Spanish version of the COMQ-12 indicated a questionnaire structure with three domains: smelly discharge related symptoms; hearing loss related symptoms; and impact on work, lifestyle and health services.Conclusion This Spanish version of the COMQ-12 showed high reliability and high internal consistency. This questionnaire can be used as an objective clinical tool to assess the HRQoL of patients who have a COM diagnosis.


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