scholarly journals Malignant Solitary Fibrous Tumor of the Pleura: Case Report

2021 ◽  
Author(s):  
Matthew S Khouzam ◽  
Nayer Khouzam
Keyword(s):  
Surgical Resection ◽  
Solitary Fibrous Tumor ◽  
Left Lung ◽  
Left Hemithorax ◽  
Solitary Fibrous Tumors ◽  
Progressive Dyspnea ◽  
Resected Tumor ◽  
Chest X Ray ◽  
Bulky Mass ◽  
Fibrous Tumor

Abstract Background: Solitary fibrous tumors of the pleura are rare diseases of the thoracic cavity. They frequently grow unnoticed until they exert compressive effects on adjacent organs. Treatment of solitary fibrous tumors of the pleura is surgical resection. Post-operative surveillance is recommended to identify early recurrent disease. Case Presentation: We present a rare case of a 76-year-old female patient with no previous pulmonary history who presented with progressive dyspnea, fatigue, and involuntary weight loss. On chest X-ray and computed chest tomography scan, she was found to have a 16.7 cm x 12.8 cm x 10.1 cm bulky mass occupying the left hemithorax with associated compressive atelectasis of the lung. She underwent a computed tomography guided biopsy that revealed the mass to be a solitary fibrous tumor. The patient underwent left muscle sparing lateral thoracotomy with complete resection of the tumor. Post procedure, the left lung fully expanded. 18 months post-resection, she developed a 3.3 cm x 1.7 cm tumor along the left internal thoracic artery lymph node chain which was histologically identical to the resected tumor. The patient is currently being treated with bevacizumab and temozolomide. Conclusion: Solitary fibrous tumors are very rare pleural tumors. Surgical resection is the treatment of choice followed by close post-operative surveillance.

scholarly journals A Solitary Fibrous Tumor of the Pleura Revealed by Hiccups

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
A. Chafik ◽  
M. Alaoui ◽  
A. Benjelloune ◽  
Y. Qamouss
Keyword(s):  
Solitary Fibrous Tumor ◽  
Similar Case ◽  
Clinical Presentation ◽  
Malignant Potential ◽  
Pleural Tumor ◽  
Solitary Fibrous Tumors ◽  
Progressive Dyspnea ◽  
Fibrous Tumor

Solitary fibrous tumors of the pleura are rare and benign primary localized tumors; they possess a malignant potential and thus should be excised. We report a case of a 43-year-old woman, who had suffered for 5 years from right basithoracic pain associated with progressive dyspnea and persistent hiccups during the last 6 months. We have not found any similar case in the literature. Further testing after excision by thoracotomy revealed a solitary fibrous pleural tumor. A brief discussion of the clinical presentation and incidence of these tumors is included.

scholarly journals Solitary Fibrous Tumor: Case Report of Intrapulmonary Location

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Adil Arsalane ◽  
Abdelfetah Zidane ◽  
Hicham Fenane ◽  
Amine Azami ◽  
Ismail Essadi ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Resection ◽  
Solitary Fibrous Tumor ◽  
Visceral Pleura ◽  
Clinical Imaging ◽  
Histological Features ◽  
Solitary Fibrous Tumors ◽  
Fibrous Tumor ◽  
Malignant Behavior

Solitary fibrous tumors are relatively rare neoplasms that commonly occur in the pleura, especially visceral pleura. However, an intrapulmonary site of this kind of tumors is even rarer. These tumors can be characterized by a heterogeneous evolution and have a benign or malignant behavior. Wide surgical resection is essential to cure the patient and to avoid recurrence. We present here the clinical, imaging, and histological features of a case with solitary fibrous tumor growing inside the lung.

scholarly journals Retroperitoneal fibrous tumor recurring as lung metastases after 10 years: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kozue Matsuishi ◽  
Kojiro Eto ◽  
Atsushi Morito ◽  
Hirokazu Hamasaki ◽  
Keisuke Morita ◽  
...  
Keyword(s):  
Case Report ◽  
Solitary Fibrous Tumor ◽  
Distant Metastasis ◽  
Curative Resection ◽  
Lung Metastases ◽  
Lung Resection ◽  
Left Lung ◽  
Metastatic Lesion ◽  
Case Presentation ◽  
Fibrous Tumor

Abstract Background Solitary fibrous tumor (SFT) is a relatively rare mesenchymal tumor that mainly affects adults. Its prognosis is good after curative resection, but distant recurrences after 10 years or longer have been reported. Recurrent SFT usually arises as a local lesion; distant metastasis is rarely reported. Here, we report lung metastases that recurred a decade after excising a retroperitoneal primary SFT. Case presentation A 44-year-old woman had an SFT resected from her right retroperitoneum at our hospital. Ten years later, at age 54, she underwent a lung resection after CT showed three suspected metastases in her left lung. All three were histologically diagnosed as lung metastases from the retroperitoneal SFT. However, whereas the primary SFT had 1–2 mitotic cells/10 high power fields (HPF), the metastatic lesion increased malignancy, at 50/10 HPF. Conclusion Patients who have had resected SFTs should be carefully followed up, as malignancy may change in distant metastasis, as in this case.

scholarly journals Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report

2021 ◽  
Vol 13 (1) ◽  
pp. 259-266
Author(s):  
Ye-Tao Zhu ◽  
Yang Liu ◽  
Li-Gang Chen ◽  
Da-Ping Song
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Solitary Fibrous Tumor ◽  
Immunohistochemical Staining ◽  
Biological Behavior ◽  
Resonance Imaging ◽  
Solitary Fibrous Tumors ◽  
The Central Nervous System ◽  
Fibrous Tumor ◽  
The Right

Solitary fibrous tumor is a very rare mesenchymal tumor that occurs mostly in the pleura, and there are few reported cases of a presence in the central nervous system, particularly in the cerebellum. In 2016, the WHO classified solitary fibrous tumors into grade I. In this article, we present a case of malignant solitary fibrous tumor recurring 8 years after surgery in a 63-year-old male. Magnetic resonance imaging showed low to intermediate mixed signal intensity on T1W1. Immunohistochemical staining positivity for Vimentin, CD99, CD34 and Bcl-2, it is consistent with the immunohistochemical characteristics of solitary fibrous tumor. We resected the patient’s tumor, and the patient was followed up for 3 months with no signs of recurrence. Solitary fibrous tumors are very rare in the central nervous system. Immunohistochemical staining positivity for CD34 and Bcl-2 is strongly expressed in most solitary fibrous tumor. Surgical resection is the preferred treatment. Due to the small number of cases, the biological behavior and prognosis of this tumor need to be further explored.

Solitary Fibrous Tumor of the Larynx: A Case Report and Review of the Literature

2006 ◽  
Vol 130 (2) ◽  
pp. 213-216 ◽  
Author(s):  
Jorge E. Dotto ◽  
William Ahrens ◽  
David J. Lesnik ◽  
Diane Kowalski ◽  
Clarence Sasaki ◽  
...  
Keyword(s):  
Case Report ◽  
Solitary Fibrous Tumor ◽  
Review Of The Literature ◽  
Solitary Fibrous Tumors ◽  
Subsequent Investigation ◽  
Mesenchymal Neoplasms ◽  
Fibrous Tumor

Abstract Solitary fibrous tumors are relatively rare mesenchymal neoplasms that were originally described as pleural- or peritoneal-based lesions. Although they were considered a form of mesothelioma, subsequent investigation failed to reveal mesothelial differentiation. Characterization of their histologic and immunohistochemical features, as well as identification in a multitude of nonmesothelial-based locations has further served to distinguish these lesions from the more diffuse and aggressive mesothelioma. Reports of solitary fibrous tumor in the larynx are extremely rare. We report a case of solitary fibrous tumor of the larynx in a 38-year-old man.

Solitary Fibrous Tumor of the Orbit With a t(9;22)(q31;p13)

2000 ◽  
Vol 124 (5) ◽  
pp. 756-758
Author(s):  
Dean M. Havlik ◽  
Denise A. Farnath ◽  
Therese Bocklage
Keyword(s):  
Solitary Fibrous Tumor ◽  
Genetic Information ◽  
Solitary Fibrous Tumors ◽  
Fibrous Tumor

Abstract Solitary fibrous tumors are well-described neoplasms found predominantly in the subpleural region but also in many other body sites. They generally behave in a benign fashion, although a few cases that exhibit a malignant course have been reported. Genetic information on solitary fibrous tumors is sparse. This case illustrates a previously unreported finding of a tumor-specific t(9;22)(q31;p13) in a solitary fibrous tumor of the orbit of a 58-year-old man.

Two case reports of rare diseases occurring in rare parts: Splenic vein solitary fibrous tumor and Liver solitary fibrous tumor

2020 ◽  
Author(s):  
Wenjing Wang ◽  
Banghe Bao ◽  
Anbin Hu ◽  
Xiaofeng Zhu ◽  
Qing Chen
Keyword(s):  
Liver Transplantation ◽  
Surgical Resection ◽  
Orthotopic Liver Transplantation ◽  
Solitary Fibrous Tumor ◽  
Primary Tumor ◽  
Splenic Vein ◽  
Tumor Site ◽  
Primary Tumor Site ◽  
Fibrous Tumor

Abstract Background Solitary fibrous tumor (SFT) is a rare soft tissue tumor originating from mesenchyme. Two cases of SFT we report right now occurred in the splenic vein and liver respectively, this primary splenic vein SFT may be the first report case, and also the first report of liver recurrence SFT cured by orthotopic liver transplantation (OLT). Case presentation One case was a 37-year-old female patient whose primary tumor site was located in the splenic vein, which resulted in splenomegaly and hypersplenism; its recurrence again and again after surgical resection and eventually transferred to the liver, during 10 years of follow-up, 4 operations were performed, and he is in a good condition right now. The second case was a 54-year-old male patient whose primary tumor site was located in the liver, spleen and left side of the chest wall; however, he had no uncomfortable symptoms. Surgeons performed two operations to remove these tumors, totally. 6 years later, SFT recurrence in the liver, and given that the tumor was so large that it could not be completely surgical resected, we chose orthotopic liver transplantation (OLT), and no tumor recurrence during 12-month follow-up. Conclusion The reports of these two cases of SFT are very rare, especially the splenic vein SFT, which expand the understanding of SFT. The main treatment of SFT is still surgical resection, right now, and liver transplantation may be a new option treatment for the huge liver SFT.

scholarly journals Case Report: A Malignant Liver and Thoracic Solitary Fibrous Tumor: A 10-Year Journey From the Brain to the Liver and the Spine

2020 ◽  
Vol 7 ◽  
Author(s):  
Min Mao ◽  
Lei Zhou ◽  
Chaojun Huang ◽  
Xudong Yan ◽  
Shuo Hu ◽  
...  
Keyword(s):  
Solitary Fibrous Tumor ◽  
Disease Free Survival ◽  
Liver Lesion ◽  
Management Plan ◽  
Gross Total Resection ◽  
Thoracic Vertebrae ◽  
Total Resection ◽  
Meningeal Tumor ◽  
Solitary Fibrous Tumors ◽  
Fibrous Tumor

Solitary fibrous tumors are rare neoplasms that originate from mesenchymal tissues and have been found to occur in any site, including the spine and liver. Although most of solitary fibrous tumors have benign features, only 10–20% are malignant and prone to metastasis. No previous reports have described the malignant and metastatic Solitary fibrous tumor arising in both of the liver and thoracic vertebrae. In this article, we present the case of a 60-year-old woman who underwent gross total resection of a meningeal tumor in 2007. She presented 10 years later with a thoracic vertebral mass that caused relentless pain and a lesion in the right lobe of liver. She underwent marginal excision of the T3 tumor with T2-4 pedicular screw fixation in March 2017, then right hemi-hepatectomy was performed to remove the liver lesion in June 2017. Both of the lesions were confirmed to be a metastatic and malignant tumor after surgery. The literature lacks randomized controlled trials and large studies that define the natural history of malignant solitary fibrous tumors and recommendations of precise management plan for the disease. However, the best choice for treatment is gross total resection, which probably provide the optimal treatment to achieve long-term disease-free survival.

Solitary Fibrous Tumor of the Parapharyngeal Space: A Case Report and Review of the Literature

1996 ◽  
Vol 75 (10) ◽  
pp. 681-684 ◽  
Author(s):  
Kunal Gangopadhyay ◽  
Khalid Taibah ◽  
M. Babu Manohar ◽  
Hala Kfoury
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Solitary Fibrous Tumor ◽  
Spindle Cell ◽  
Parapharyngeal Space ◽  
English Literature ◽  
Review Of The Literature ◽  
Solitary Fibrous Tumors ◽  
Rare Location ◽  
Fibrous Tumor

Solitary fibrous tumors are uncommon spindle cell neoplasms generally associated with serosal surfaces, especially the pleura. Recently, these tumors have been documented in a number of extrapleural sites including the head and neck. So far only two cases of parapharyngeal solitary fibrous tumor have been reported in the English literature. Rare location of an uncommon lesion often gives rise to difficulty in diagnosis or to misdiagnosis. In both the previously reported cases, as well as in our case, the diagnosis of solitary fibrous tumor was not made until the excised tumor was subjected to histopathology and immunohistochemistry.

scholarly journals Solitary Fibrous Tumors and So-Called Hemangiopericytoma

Sarcoma ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Nicolas Penel ◽  
Eric Yaovi Amela ◽  
Gauthier Decanter ◽  
Yves-Marie Robin ◽  
Perrine Marec-Berard
Keyword(s):  
Solitary Fibrous Tumor ◽  
Targeted Therapies ◽  
Standard Treatment ◽  
Tumor Biology ◽  
Special Focus ◽  
Solitary Fibrous Tumors ◽  
Systemic Treatments ◽  
Localized Disease ◽  
Definition Of ◽  
Fibrous Tumor

We have reviewed the literature data regarding the spectrum of tumors including solitary fibrous tumor and hemangiopericytoma with special focus on definition of the disease, discussion of the criteria for malignancy, and the key elements of standard treatment of localized disease. We have discussed the emerging concepts on the tumor biology and the different systemic treatments (chemotherapy and molecular-targeted therapies).

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