scholarly journals New Method for Examining Association Between Obesity and Diabetes With Age Among Korean Adults

Author(s):  
Nam Lyong Kang

Abstract This study examined the age-dependence of the association between diabetes and obesity among Korean adults. The data from the Seventh Korean National Health and Nutrition Examination Survey (2017) were analyzed. This paper considered the body mass index (BMI) and waist-to-height ratio (WHT2R) as obesity indices and the fasting blood glucose (FBG) as a diabetes index and used their lump mean values and the regression method. The WEHT2R was a more suitable index for examining the FBG than the BMI. The increase in the WHT2R of females was more sensitive to age than that of males. In contrast, the increase in the FBG of males was more sensitive to age than that of females. The ages that FBG increased to 100.0 mg/DL were 44.7 and 60.5 years for males and females, respectively. Korean adults should reduce their WHT2R to prevent the excessive increase in their FBG level and Korean males should take care of their FBG from a young age. The present results can be used for a preliminary inspection of diseases, such as functional degradation of Langerhans islets and gestational diabetes

2019 ◽  
Vol 53 (4) ◽  
pp. 325-334
Author(s):  
V. N. Peskov ◽  
N. A. Petrenko ◽  
V. Yu. Reminnyi

Abstract We study size-at-age and sexual variability of morphometric characteristics of the marsh frog. According to the size of the body, males were divided into three size-age groups (juvenis, subadultus, adultus), females — into four groups (juvenis, subadultus, adultus, adultus-I). We found that the chronological age of frogs (skeletochronology) does not always correspond to their biological age (size and proportions of the body). We noted that the semi-adult males are reliably larger than females by mean values of 26 studied morphometric characters. Males and females of “adultus” group do not differ by linear body size, significant differences were found in body proportions (7 characters). For the females of “adultus-I” group, the mean values of 26 characters are significantly larger than for “adultus” males. The results of our study showed that with the age of the marsh frog, the level of exhibition, directionality and structure of morphometric sex differences changes.


2015 ◽  
Vol 1 (1) ◽  
pp. 5-12 ◽  
Author(s):  
Alexander Čanády ◽  
Ladislav Mošanský ◽  
Peter Krišovský

Abstract Sexual dimorphism of the Eurasian red squirrel on five somatic variables (head-and-body length, tail length, hind foot length, ear length and body weight) was evaluated on 55 squirrels. The overlap of values of the measured traits among sexes was high, but in all traits (with exception of the tail length) males seem to exhibit slightly higher mean values than females. However, these differences were non-significant, with the exception of a small significant difference in the tail length and tail-to-head-and-body ratio. Similarly, the results of discriminant function analysis show no differences between the sexes. Positive correlation analyses, together with PCA values, confirmed that tail length and hind foot length are traits that play a significant role in overall variability. We suggest that this relationship could explain their mutual importance in locomotion, where the feet are essential for movement in the trees. By contrast, the tail maintains balance on thin branches, or during jumps from one crown to another. Longer tails also demonstrate differential selection on males and females for a locomotor trait. Similarly, we discuss whether variations in tail length were connected to female reproductive success. Our results suggest that the non-significant results regarding SSD provide the benefit of the same size for both sexes in the protection of territory as well as inter- and intra-sexual interaction.


2019 ◽  
Vol 12 (4) ◽  
pp. 246-252 ◽  
Author(s):  
Kyung Hee Lee ◽  
Hea Shoon Lee

Abstract Background Asthma is a chronic inflammatory disease that may associate with other chronic diseases such as hypertension and diabetes. We observed the effects of blood pressure (BP), fasting blood glucose (FBG), haemoglobin A1c (HbA1c) and insulin on asthma in Korean adults. Methods Data from 5045 adults were taken from the 2015 Sixth Korea National Health and Nutrition Examination Survey and analysed using a multiple logistic regression model. Results By age, the probability of asthma occurrence was 1.02 times higher (adjusted odds ratio [aOR] 1.02 [95% CI 1.01 to 1.03]). Specifically, asthma occurrence was increased in individuals >66 years of age (aOR 2.40 [95% CI 1.22 to 4.72]). The probability of asthma occurrence in females was higher than in males (aOR 1.73 [95% CI 1.02 to 2.84]). Hypertension and systolic blood pressure (SBP) were found to increase the probability of asthma occurrence by 1.43- and 1.03-fold, respectively. Diabetes mellitus (DM) was another factor that increased with the occurrence of asthma (aOR 1.75 [95% CI 1.06 to 3.02]). The probability of asthma occurrence was not increased with the FBG level, whereas HbA1c (aOR 1.38 [95% CI 1.03 to 1.84]) and insulin levels (aOR 1.02 [95% CI 1.01 to 1.04]) were shown to increase the occurrence of asthma. Conclusions Age, sex, hypertension, SBP, DM, HbA1c and insulin levels are all factors that may influence the occurrence of asthma in Korean adults. In particular, hypertension and diabetes emerge from the present study as potential associated factors for the development of asthma.


2015 ◽  
Vol 21 (3) ◽  
pp. 194-201 ◽  
Author(s):  
Ashutosh Chaturvedi ◽  
Prasanna N. Rao ◽  
M. Ashvini Kumar ◽  
B. Ravishankar ◽  
Niranjan Rao ◽  
...  

Background. Panchakarma (biopurification methods) is one of the modes of ayurveda to treat disorders of the body. Virechana karma (therapeutic purgation), one among the Panchakarma, is a purification process that is commonly used to treat metabolic disorders like obesity and diabetes mellitus. Hence this study was planned to provide evidence through animal experiments. Methods. Albino rats were subject to Virechana karma (therapeutic purgation) to evaluate the influence of therapy and its mechanism over fructose-induced metabolic syndrome. Results. Results show that Virechana is effective in the management of the metabolic syndrome with decrease in the fecal fat content, fasting blood glucose, serum triglyceride, and reduced fatty changes in liver, heart, and kidney in comparison with the positive control group. Conclusion. Experimental evaluation showed decrease in fatty acid in the storage like liver, kidney, heart, and muscle adipose tissue can indirectly increase the insulin sensitivity in insulin receptor present at skeletal muscles.


2004 ◽  
Vol 180 (3) ◽  
pp. 357-368 ◽  
Author(s):  
S Wei ◽  
Y Feng ◽  
FY Che ◽  
H Pan ◽  
N Mzhavia ◽  
...  

ProSAAS is a neuroendocrine peptide precursor that potently inhibits prohormone convertase 1 in vitro. To explore the function of proSAAS and its derived peptides, transgenic mice were created which express proSAAS using the beta-actin promoter. The body weight of transgenic mice was normal until approximately 10-12 weeks, and then increased 30-50% over wild-type littermates. Adult transgenic mice had a fat mass approximately twice that of wild-type mice, and fasting blood glucose levels were slightly elevated. In the pituitary, the levels of several fully processed peptides in transgenic mice were not reduced compared with wild-type mice, indicating that the proSAAS transgene did not affect prohormone convertase 1 activity in this tissue. Because the inhibitory potency of proSAAS-derived peptides towards prohormone convertase 1 is much greater in the absence of carboxypeptidase E activity, the proSAAS transgene was also expressed in carboxypeptidase E-deficient Cpe (fat/fat) mice. Although the transgenic mice were born in the expected frequency, 21 of 22 proSAAS transgenic Cpe (fat/fat) mice died between 11 and 26 weeks of age, presumably due to greatly elevated blood glucose. The levels of several pituitary peptides were significantly reduced in the proSAAS transgenic Cpe (fat/fat) mice relative to non-transgenic Cpe (fat/fat) mice, suggesting that the transgene inhibited prohormone convertase 1 in these mice. Taken together, these results are consistent with a role for proSAAS-derived peptides as neuropeptides that influence body weight independently of their function as inhibitors of prohormone convertase 1.


2019 ◽  
Author(s):  
Yu-mi Gi ◽  
Boyoung Jung ◽  
Koh-Woon Kim ◽  
Jae-Heung Cho ◽  
In-Hyuk Ha

ABSTRACTBackgroundAnemia occurs because of insufficient hemoglobin, which provides oxygen to the body. Because of its close relationship with various illnesses, it must always be investigated clinically. Previous studies have demonstrated an association between hemoglobin concentration and handgrip strength. Thus, we aimed to analyze the association between handgrip strength and anemia in Korean adults to determine whether the handgrip strength test can be used as a tool to identify anemia.MethodsThe research subjects’ data were extracted from the 6th and 7th Korean National Health and Nutrition Examination Survey, between January 2013 and December 2017. Overall, data of 16,637 adults (weighted n= 9,734,598) were analyzed. Differences in sociodemographic factors (sex, age, education, income, and employment), lifestyle factors (alcohol consumption, smoking, and physical activity), and illness and health factors (body mass index, vitamin intake, iron intake, comorbid illnesses, and handgrip strength) by existence of anemia were analyzed using a chi square test. Binary logistic regression was performed to identify factors of anemia. Subgroup analysis, stratified by sex and age, was performed.ResultsAmong Korean adults aged ≥ 19 years, 745,296 (7.7%) had anemia. Higher odds ratio (OR) of anemia occurred in the weak handgrip strength group compared to the strong handgrip strength group (OR=1.92, 95% CI: 1.58-2.33). The subgroup analysis showed a higher OR for anemia in the weak handgrip strength group than in the strong handgrip strength group, regardless of sex or age. However, the results showed that this association was greater for males (OR=2.13, 95% CI: 1.35-3.34) and for those aged ≥65 years (OR=1.92, 95% CI: 1.42-2.58).ConclusionThis study showed a strong association between handgrip strength and anemia, which was particularly strong for males and those aged ≥65 years. Therefore, it is anticipated that handgrip strength can be used in anemia screening tests as a useful tool.


2020 ◽  
Author(s):  
Nam Lyong Kang

Abstract Background The aim of this study was to the investigate association of high blood pressure (BP) and wide pulse pressure (PP) with obesity among common Korean people. Method This study analyzed data from the Seventh Korean National Health and Nutrition Examination Survey (2017). The associations of BP with body mass index (BMI) and waist-to-height ratio (WHT2R) were investigated using their lump mean values.Results The BPs of males and females increased with BMI, the PP of females increased with BMI and then decreased, and the PP of males is nearly independent of BMI. The BPs of males and females increased to their maximum values with WHT2R and then decreased. The PPs of males and females increased with WHT2R.Conclusions BMI can be used as a useful predictor for high BP, and WHT2R can be used as a useful predictor for wide PP.


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