scholarly journals Hypoalbuminemia in Severe COVID-19 Post Recovery Patients

2020 ◽  
Author(s):  
Kameran Mohammed Ali ◽  
Ayad M. Ali ◽  
Hassan Mohammad Tawfeeq ◽  
Grazziela Figueredo ◽  
Hassan Muhammad Rostam
Keyword(s):  
Serum Albumin ◽  
Negative Correlation ◽  
Serum Albumin Level ◽  
Albumin Level ◽  
Strong Negative Correlation ◽  
Positive Correlation ◽  
Contagious Disease ◽  
Severe Group ◽  
Recovery Status

Abstract Pandemic Coronavirus disease 2019 (COVID-19) is a contagious disease affecting more than 200 countries, territories and regions. Thousands of studies have dealt with all aspects of the disease but little is known about post recovery status of the patients. Here, we examined ESR, CRP and serum albumin biomarkers in severe and mild-moderate COVID-19 post recovery patients. In severe group patients, serum albumin had a strong negative correlation with both ESR and CRP (R2= -0.861), (R2= -0.711) respectively. Also, there was a positive correlation between ESR and CRP (R2=0.85) in the same group. However, there was no correlation among mild-moderate group patients in those biomarkers. In addition, no correlation recorded between severe and mild-moderate groups. This finding concludes the sustained elevation of ESR and CRP with decreased serum albumin level in severe COVID-19 post recovery patients.

scholarly journals Role of Microalbuminuria and Hypoalbuminemia as Outcome Predictors in Critically Ill Patients

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Mahmoud Nour ◽  
Abdelhaleem hegazy ◽  
Abeer mosbah ◽  
Ahmed Abdelaziz ◽  
Mohamed Fawzy
Keyword(s):  
Serum Albumin ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Serum Albumin Level ◽  
Albumin Level ◽  
Strong Positive Correlation ◽  
Creatinine Ratio ◽  
Icu Patients ◽  
Albumin Creatinine Ratio ◽  
Positive Correlation

Background. Assessment of microalbuminuria and hypoalbuminemia can be used as a good tool for the prediction of the ICU outcome in critically ill patients. Purpose. To evaluate and compare the prognostic significance of microalbuminuria (albumin creatinine ratio (ACR)) and serum albumin level done on admission and after twenty-four hours for the critically ill patients. Methodology. Sixty ICU patients were involved in a prospective cohort study (mean age was 44.4 ± 16.7 years, and 78.3% were males). Patients were divided into 2 groups according to mortality (survivors and nonsurvivors) and were subjected to laboratory measurement of the mentioned biomarkers on admission and after twenty-four hours. Results. There were 34 patients (56.67%) in group A (survivors) and 26 patients (43.33%) in group B (nonsurvivors). Albumin creatinine ratio on admission (ACR1) and albumin creatinine ratio after 24 hours (ACR2) were significantly lower in survivors than nonsurvivors ( P values were <0.001 for both). Serum albumin level after 24 hours of admission was significantly higher in survivors than nonsurvivors ( P value 0.02) while admission serum albumin was not significantly different between both groups ( P value was 0.1). There was a positive correlation between ACR2 and ICU stay and mechanical ventilatory support with a strong positive correlation with the use of vasopressor therapy (r: 0.35, 0.58, and 0.73, respectively). P values were 0.005, <0.0001, and <0.0001, respectively. There was a positive correlation between ACR2 with APACHE II and SOFA scores (r: 0.46 and 0.43, respectively); P values were 0.001 and <0.0001, respectively. There was a moderate negative correlation between serum albumin on admission and after 24 hours and the duration of mechanical ventilation (r: −0.4 and −0.39, respectively) ( P values were 0.001 and 0.002, respectively). By Cox regression analysis, two parameters were found to be an independent predictor of mortality in ICU patients which were age and using vasopressor treatment ( P values = 0.01 and <0.001), while the other parameters were not independent predictors of mortality ( P values were more than 0.05). Conclusions. Microalbuminuria on admission and after 24 hours of ICU admission could be a good predictor of mortality in critically ill patients. The serum albumin level after 24 hours of admission can predict poor outcomes in critically ill patients.

scholarly journals The Level of Serum Albumin Is Associated with Renal Prognosis in Patients with Diabetic Nephropathy

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Junlin Zhang ◽  
Rui Zhang ◽  
Yiting Wang ◽  
Hanyu Li ◽  
Qianqian Han ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Diabetic Nephropathy ◽  
Serum Albumin ◽  
Serum Albumin Level ◽  
Cox Regression ◽  
Albumin Level ◽  
Renal Outcome ◽  
Cox Regression Analysis ◽  
Severe Group ◽  
Renal Prognosis

Objective. Although hypoalbuminemia is frequently found in most patients with diabetic nephropathy (DN), its relationship to the severity and progression of DN remains largely unknown. Our aim was to investigate the association between the serum albumin levels and clinicopathological features and renal outcomes in patients with type 2 diabetes mellitus (T2DM) and biopsy-proven DN.Materials and Methods. A total of 188 patients with T2DM and biopsy-proven DN followed up for at least one year were enrolled. The patients were divided into four groups based on the albumin levels: normal group: ≥35 g/L (n=87); mild group: 30-35 g/L (n=34); moderate group: 25-30 g/L (n=36); and severe group: <25 g/L (n=31). The renal outcome was defined by progression to end-stage renal disease. The impact of the serum albumin level on renal survival was estimated using Cox regression analysis.Results. Among the cases, the serum albumin level had a significant correlation with proteinuria, renal function, and glomerular lesions. A multivariate Cox regression analysis indicated that the severity of hypoalbuminemia remained significantly associated with an adverse renal outcome, independent of clinical and histopathological features. In reference to the normal group, the risk of progression to ESRD increased such that the hazard ratio (HR) for the mild group was 2.09 (95% CI, 0.67-6.56,p=0.205), 6.20 (95% CI, 1.95-19.76,p=0.002) for the moderate group, and 7.37 (95% CI, 1.24-43.83,p=0.028) for the severe group.Conclusions. These findings suggested that hypoalbuminemia was associated with a poorer renal prognosis in patients with T2DM and DN.

scholarly journals Hubungan antara Kadar Serum Albumin Awal dengan Lama Rawat Inap dan Status Pulang Pasien Dewasa di Rumah Sakit

2004 ◽  
Vol 1 (1) ◽  
pp. 19
Author(s):  
Weni Kurdanti ◽  
Hamam Hadi ◽  
Susetyowati Susetyowati
Keyword(s):  
Length Of Stay ◽  
Serum Albumin ◽  
Serum Albumin Level ◽  
Albumin Level ◽  
Normal Serum ◽  
Hospital Death ◽  
Increased Risk ◽  
Neurological Patients ◽  
Recovery Status ◽  
Low Serum

Background: Several community studies have reported a relationship between a low serum albumin level and increased risk of hospital death, nosocomial infection, and length of stay. But this kind of study is still lacking in Indonesia.Objective: To assess the relationship between admission serum albumin levels with length of stay and recovery rate among adult hospitalized patients.Methods: This cohort study was done in 2002. Subjects of this study were adults, inpatient of internal and neurological departments of Dr.Sardjito, Dr. M. Jamil and Sanglah hospitals. Serum albumin level, total lymphocyte count (TLC), and hemoglobin from each subject were collected at the admission. Energy intake of each subject was obtained using visual Comstock method. Information of length of stay and recovery status at discharge was obtained from medical records.Results: On average the length of stay (LOS) in patients with normal serum albumin was 9.8 days. In patients with low serum albumin the LOS was 2 days longer (p<0.05) than that in patient with normal serum albumin. LOS was not significantly different by serum albuminlevels among neurological and cancer patients. Neurological patients with low serum albumin had 10 times greater risk for not recover on discharge than non neurological patients with normal serum albumin.Conclusion: Serum albumin level at admission was associated with LOS and recovery status on discharge.

scholarly journals Low Serum Albumin Level is Risk Factor for Patients with Percutaneous Endoscopic Gastrostomy

2010 ◽  
Vol 49 (21) ◽  
pp. 2283-2288 ◽  
Author(s):  
Naoyuki Tominaga ◽  
Ryo Shimoda ◽  
Ryuichi Iwakiri ◽  
Nanae Tsuruoka ◽  
Yasuhisa Sakata ◽  
...  
Keyword(s):  
Risk Factor ◽  
Serum Albumin ◽  
Percutaneous Endoscopic Gastrostomy ◽  
Serum Albumin Level ◽  
Albumin Level ◽  
Endoscopic Gastrostomy ◽  
Low Serum

scholarly journals Spatial Variation of the Relationship between PM2.5Concentrations and Meteorological Parameters in China

2015 ◽  
Vol 2015 ◽  
pp. 1-15 ◽  
Author(s):  
Gang Lin ◽  
Jingying Fu ◽  
Dong Jiang ◽  
Jianhua Wang ◽  
Qiao Wang ◽  
...  
Keyword(s):  
Negative Correlation ◽  
Meteorological Parameters ◽  
Semiarid Region ◽  
Strong Positive Correlation ◽  
Annual Average ◽  
Strong Negative Correlation ◽  
Positive Correlation ◽  
Humid Region ◽  
The Relationship ◽  
Warm Temperate

Epidemiological studies around the world have reported that fine particulate matter (PM2.5) is closely associated with human health. The distribution of PM2.5concentrations is influenced by multiple geographic and socioeconomic factors. Using a remote-sensing-derived PM2.5dataset, this paper explores the relationship between PM2.5concentrations and meteorological parameters and their spatial variance in China for the period 2001–2010. The spatial variations of the relationships between the annual average PM2.5, the annual average precipitation (AAP), and the annual average temperature (AAT) were evaluated using the Geographically Weighted Regression (GWR) model. The results indicated that PM2.5had a strong and stable correlation with meteorological parameters. In particular, PM2.5had a negative correlation with precipitation and a positive correlation with temperature. In addition, the relationship between the variables changed over space, and the strong negative correlation between PM2.5and the AAP mainly appeared in the warm temperate semihumid region and northern subtropical humid region in 2001 and 2010, with some localized differences. The strong positive correlation between the PM2.5and the AAT mainly occurred in the mid-temperate semiarid region, the humid, semihumid, and semiarid warm temperate regions, and the northern subtropical humid region in 2001 and 2010.

Serum albumin level accurately reflects antioxidant potentials in idiopathic nephrotic syndrome

2011 ◽  
Vol 16 (3) ◽  
pp. 411-414 ◽  
Author(s):  
Kazunari Kaneko ◽  
Takahisa Kimata ◽  
Shoji Tsuji ◽  
Tomohiko Shimo ◽  
Masaya Takahashi ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Serum Albumin ◽  
Serum Albumin Level ◽  
Idiopathic Nephrotic Syndrome ◽  
Albumin Level

Association of preoperative hypoalbuminemia with postoperative acute kidney injury in patients undergoing brain tumor surgery: a retrospective study

2018 ◽  
Vol 128 (4) ◽  
pp. 1115-1122 ◽  
Author(s):  
Kyungmi Kim ◽  
Ji-Yeon Bang ◽  
Seon-Ok Kim ◽  
Saegyeol Kim ◽  
Joung Uk Kim ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Brain Tumor ◽  
Serum Albumin ◽  
Serum Albumin Level ◽  
Kidney Injury ◽  
Albumin Level ◽  
Tumor Surgery ◽  
Brain Tumor Surgery ◽  
Preoperative Serum ◽  
Postoperative Aki

OBJECTIVEHypoalbuminemia is known to be independently associated with postoperative acute kidney injury (AKI). However, little is known about the association between the preoperative serum albumin level and postoperative AKI in patients undergoing brain tumor surgery. The authors investigated the incidence of AKI, impact of preoperative serum albumin level on postoperative AKI, and death in patients undergoing brain tumor surgery.METHODSThe authors retrospectively reviewed the electronic medical records and laboratory results of 2363 patients who underwent brain tumor surgery between January 2008 and December 2014. Postoperative AKI was defined according to Kidney Disease: Improving Global Outcomes Definition and Staging (KDIGO). Multivariate logistic regression analysis was used to identify demographic, preoperative laboratory, and intraoperative factors associated with AKI development. Cox proportional hazards models were used to investigate the adjusted odds ratio and hazard ratio for the association between preoperative serum albumin level and outcome variables.RESULTSThe incidence of AKI was 1.8% (n = 43) using KDIGO criteria. The incidence of AKI was higher in patients with a preoperative serum albumin level < 3.8 g/dl (3.5%) than in those with a preoperative serum albumin level ≥ 3.8 g/dl (1.2%, p < 0.001). The overall mortality was also higher in the former than in the latter group (5.0% vs 1.8%, p < 0.001). After inverse probability of treatment-weighting adjustment, a preoperative serum albumin level < 3.8 g/dl was also found to be associated with postoperative AKI (OR 1.981, 95% CI 1.022–3.841; p = 0.043) and death (HR 2.726, 95% CI 1.522–4.880; p = 0.001).CONCLUSIONSThe authors’ results demonstrated that a preoperative serum albumin level of < 3.8 g/dl was independently associated with AKI and mortality in patients undergoing brain tumor surgery.

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