scholarly journals Weight Encode Reconstruction Network for Computed Tomography in a Semi-Case-Wise and Learning-Based Way

2020 ◽  
Author(s):  
Hujie Pan ◽  
Xuesong Li ◽  
Min Xu

Abstract Classic algebraic reconstruction technology (ART) for computed tomography requires pre-determined weights of the voxels for the projected pixel values to build the equations. However, such weights cannot be accurately obtained due to the high physical complexity and computation resources required. In this study, we propose a semi-case-wise learning-based method named Weight Encode Reconstruction Network (WERNet) to co-learn the target voxel values and intrinsic physics of the case in a self-supervised manner without labeling the target voxel set. With the help of gradient normalization, the WERNet reconstructed voxel set with a high accuracy and showed a higher capability of denoising compared to the classic ART methods. Moreover, the encoder of the network is transferable from a voxel set with complex structures to unseen cases without the deduction of the accuracy. Our method can be applied in tomography-related applications and similar inversion problems even with unclear intrinsic physics.

Author(s):  
Christoph I. Lee

This chapter, found in the abdominal and pelvic pain section of the book, provides a succinct synopsis of a key study examining the use of ultrasound and computed tomography (CT) among children with suspected appendicitis. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. The study showed that CT with contrast after a negative or indeterminate pelvic ultrasound leads to very high accuracy in diagnosing acute appendicitis in children. In addition to outlining the most salient features of the study, a clinical vignette and imaging example are included in order to provide relevant clinical context.


2011 ◽  
Vol 18 (8) ◽  
pp. 2265-2272 ◽  
Author(s):  
Daniele Marrelli ◽  
Maria Antonietta Mazzei ◽  
Corrado Pedrazzani ◽  
Marianna Di Martino ◽  
Carla Vindigni ◽  
...  

2007 ◽  
Vol 25 (4) ◽  
pp. 384-389 ◽  
Author(s):  
Allison E. Axtell ◽  
Margaret H. Lee ◽  
Robert E. Bristow ◽  
Sean C. Dowdy ◽  
William A. Cliby ◽  
...  

Purpose Identify features on preoperative computed tomography (CT) scans to predict suboptimal primary cytoreduction in patients treated for advanced ovarian cancer in institution A. Reciprocally cross validate the predictors identified with those from two previously published cohorts from institutions B and C. Patients and Methods Preoperative CT scans from patients with stage III/IV epithelial ovarian cancer who underwent primary cytoreduction in institution A between 1999 and 2005 were retrospectively reviewed by radiologists blinded to surgical outcome. Fourteen criteria were assessed. Crossvalidation was performed by applying predictive model A to the patients from cohorts B and C, and reciprocally applying predictive models B and C to cohort A. Results Sixty-five patients from institution A were included. The rate of optimal cytoreduction (≤ 1 cm residual disease) was 78%. Diaphragm disease and large bowel mesentery implants were the only CT predictors of suboptimal cytoreduction on univariate (P < .02) and multivariate analysis (P < .02). In combination (model A), these predictors had a sensitivity of 79%, a specificity of 75%, and an accuracy of 77% for suboptimal cytoreduction. When model A was applied to cohorts B and C, accuracy rates dropped to 34% and 64%, respectively. Reciprocally, models B and C had accuracy rates of 93% and 79% in their original cohorts, which fell to 74% and 48% in cohort A. Conclusion The high accuracy rates of CT predictors of suboptimal cytoreduction in the original cohorts could not be confirmed in the cross validation. Preoperative CT predictors should be used with caution when deciding between surgical cytoreduction and neoadjuvant chemotherapy.


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