scholarly journals Comparative evaluation of osteoprotegerin levels in patient with chronic periodontitis before and after scaling and root planning ( a clinico biochemical study)

2018 ◽  
Vol 5 (3) ◽  
pp. 57-66
Author(s):  
CK Anil ◽  
◽  
Pradeep Shukla ◽  
Prerna Kataria ◽  
Gaurav Mahotra ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Comparative Evaluation ◽  
Biochemical Study ◽  
Before And After ◽  
Root Planning ◽  
Scaling And Root Planning

scholarly journals Determining Relative Percentage Change as a New Metrics in Scaling and Root Planning Therapy Outcome in Patients with Chronic Periodontitis

2021 ◽  
pp. 36-43
Author(s):  
Abdul Samad Aziz ◽  
Rahul Kale ◽  
Madhav Govind Kalekar ◽  
Adinath Narayan Suryakar
Keyword(s):  
Oxidative Stress ◽  
Chronic Periodontitis ◽  
Biochemical Parameters ◽  
Biochemical Study ◽  
Percentage Change ◽  
Therapy Outcome ◽  
Clinical Parameters ◽  
Relative Percentage ◽  
Root Planning ◽  
Scaling And Root Planning

Aims: To quantify the relative percentage change in the patients with periodontitis after employing the scaling and root planning (SRP) therapy and determine the association in the improvements in clinical parameters of biochemical oxidative stress (OS) markers, total antioxidant capacity (TAOC), and malondialdehyde (MDA). Study Design: In this cross sectional study, two groups of patients were clinically evaluated and their biochemical parameters were quantified and statistically compared. Place and Duration of Study: Departments of Biochemistry and Periodontology, M. A. Rangoonwala Dental College, Pune and Department of Biochemistry, Grant Govt. Medical College, Mumbai. The study was carried out between May 2010 and July 2012. Methodology: Individuals with generalized chronic periodontitis (n = 86; CAL ≥ 3mm American Academy of Periodontology 1999 criteria) were clinically (Gingival index, plaque index, probing depth, clinical attachment level) and biochemically (TAOC, MDA) evaluated. The SRP therapy was performed and a follow-up was done after 3 months. The mean values of clinical and biochemical study parameters and their relative percentage change were evaluated thoroughly. Results: Individuals with chronic periodontitis showed improved clinical and biochemical oxidative stress (OS) markers. After the SRP therapy, significant improvement (p ˂ 0.05) was found in both clinical and biochemical parameters from their corresponding pre-treatment values. The relative percentage change in clinical parameters ranged between 14.5% to 38.7%, and those of TAOC and MDA were -10.3% and 34.71% respectively. Further, the relative % change in TAOC and MDA showed significant correlation (p ˂ 0.05) to those of PI, PD, and CAL. Conclusion: On conducting the SRP therapy, improvement in clinical parameters and biochemical OS parameters is noticed in the individuals with periodontitis. The relative percentage change can be used as a tool for therapy outcome assessment.

scholarly journals Silver-Based Chemical Device as an Adjunct of Domestic Oral Hygiene: A Study on Periodontal Patients

Materials ◽  
2018 ◽  
Vol 11 (8) ◽  
pp. 1483 ◽  
Author(s):  
Valentina Candotto ◽  
Dorina Lauritano ◽  
Francesco Carinci ◽  
Carlo Bignozzi ◽  
Daniele Pazzi ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Microbiological Analysis ◽  
Radiographic Evidence ◽  
Paired Samples ◽  
Before And After ◽  
Microbial Analysis ◽  
Polymerase Chain ◽  
Root Planning ◽  
New Strategies ◽  
Observation Period

The use of chemical devices for periodontitis treatment has led to new strategies aiming primarily to control infections. Over the last few years, new chemical devices have been subjected to many scientific and medical studies. The purpose of the present study was to assess the effect of a new silver based chemical devices gel named “Hydrosilver Plus Gel”, abbreviated here as Hydrosilver, on the pathogenic microorganisms, using Polymerase Chain Reaction (PCR) for microbiological analysis. Materials and methods: Ten patients with a diagnosis of chronic periodontitis in the age group >25 years were selected. None of these patients had received any surgical or non-surgical periodontal therapy, and demonstrated radiographic evidence of moderate bone loss. After scaling and root planning, patients received Hydrosilver to be used at home. Four non-adjacent sites in separate quadrants were selected in each patient for monitoring, based on criteria that the sites localise chronic periodontitis. Microbial analysis was analysed at baseline and at Day 15. SPSS program was used for statistical purposes and a paired samples correlation was performed at the end of the observation period. Results: Mean amounts of bacterial loading before and after Hydrosilver treatment reduced statistically significantly (p = 0.002). Conclusions: The present study demonstrated that Hydrosilver has a good impact on oral biofilm. Additional studies are needed to detect the efficacy of this chemical device.

scholarly journals The Effects of Salvia officinalis Gel as an Adjunct to Scaling and Root Planning in Patients with Periodontitis (Clinical and Immunological Study)

2020 ◽  
Vol 10 (02) ◽  
pp. 232-237
Author(s):  
Ismael W. Aljuboori ◽  
Maha Sh. Mahmood
Keyword(s):  
Transforming Growth Factor Beta ◽  
Chronic Periodontitis ◽  
Transforming Growth Factor ◽  
Gingival Crevicular Fluid ◽  
Test Group ◽  
Control Group ◽  
Growth Factor Beta ◽  
Crevicular Fluid ◽  
Root Planning ◽  
Scaling And Root Planning

Background: Phytotherapy is the usage of herbal species with medicinal properties for the management of various diseases. Gingivitis and periodontitis are diseases that involve the role of both the bacteria and the host immune response. Over the years, various researches have shown the importance of herbal products in the management of periodontal diseases. Aims of the study: To evaluate the efficacy of locally applied Salvia officinalis gel as adjunctive in the treatment of chronic periodontitis. Subjects and methods: Fourteen patients (10 males and 4 females) with chronic periodontitis were enrolled in the present study with total number of twenty-eight periodontal pockets utilizing a split mouth design, the pockets were divided into two groups, the test group which was treated with scaling and root planning procedure and the application of the S. officinalis gel, and the control group that treated with scaling and root planning only. Plaque index (PI) and gingival index (GI) were recorded for each site. Gingival crevicular fluid (GCF) was collected from each site by using PerioCol paper strips. The concentration of the transforming growth factor beta-1 in the gingival crevicular fluid was quantified by a high sensitivity enzyme-linked immunosorbent assay. Results: The test group demonstrated a significant reduction in GI at 1-week and 1-month after the treatment comparing to baseline (1.14 vs. 1.64, p = 0.003, and 1.21 vs. 1.64, p = 0.028, respectively), while no significant reduction in the PI at recall visits comparing to baseline. The control group demonstrated no significant reduction in PI and GI at recall visits, comparing to baseline. Both the test and control groups demonstrated no significant reduction in the transforming growth factor-beta 1 concentration in the gingival crevicular fluid at one week after the treatment comparing to baseline, while at one month after the treatment only the test group demonstrated a significant reduction comparing to baseline (3.91 vs. 9.62, p = 0.044). Conclusion: The findings of the present study indicated that the S. officinalis gel has a potential anti-inflammatory role in the treatment of chronic periodontitis by monitoring both the clinical and immunological parameters.

scholarly journals The Effect of Scaling and Root Planning on Salivary TNF-α and IL-1α Concentrations in Patients with Chronic Periodontitis

2017 ◽  
Vol 11 (1) ◽  
pp. 573-580 ◽  
Author(s):  
Masoome Eivazi ◽  
Negar Falahi ◽  
Nastaran Eivazi ◽  
Mohammad Ali Eivazi ◽  
Asad Vaisi Raygani ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Interleukin 1 ◽  
Negative Relationship ◽  
Inflammatory Factors ◽  
Control Group ◽  
Pocket Depth ◽  
Necrosis Factor Alpha ◽  
Tnf Α ◽  
Root Planning ◽  
Scaling And Root Planning

Objective:Periodontitis is one of the main diseases in the oral cavity that causes tooth loss. The host immune response and inflammatory factors have important role in periodontal tissue. The current study was done with the objective to determine the effect of scaling and root planning on the salivary concentrations of tumor necrosis factor-alpha (TNF-α) and interleukin-1-alpha (IL-1α).Methods:In this quasi-experimental clinical trial, 29 patients with chronic periodontitis and 29 healthy subjects without periodontitis were studied. Clinical examination findings and salivary TNF-α and IL-1α (using ELISA method) were compared before and after scaling, root planning.Results:Before starting treatment, salivary TNF-α and IL-1α concentrations were higher in healthy control group than in periodontitis group (P< 0.05). Non-surgical treatment increased the concentration of these two biomarkers in the saliva. However, increase in IL-1α concentration was not statistically significant (P= 0.056). There was a negative relationship between TNF-α and IL-1α levels with pocket depth and attachment loss (P< 0.05).Conclusion:Scaling and root planning improved periodontal disease indices and salivary TNF-α and IL-1α levels.

scholarly journals Effectiveness of the adjunctive use of ozone and chlorhexidine in patients with chronic periodontitis

BDJ Open ◽  
2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Kaveri Kranti Gandhi ◽  
Emil G. Cappetta ◽  
Rajdeep Pavaskar
Keyword(s):  
Chronic Periodontitis ◽  
Gold Standard ◽  
Gingival Index ◽  
Periodontal Pathogens ◽  
Ozone Therapy ◽  
Clinical Attachment Loss ◽  
Probing Depth ◽  
Root Planning ◽  
Scaling And Root Planning

Abstract Background Scaling and root planning (SRP) is the gold standard approach for treatment of chronic periodontitis but used alone it may not be effective in removing periodontal pathogens from sites where access is poor. Objective To evaluate and compare the clinical and microbiological efficacy of ozone and chlorhexidine (CHX) as an adjunct to SRP in patients with chronic periodontitis. Methods Twenty-five patients with generalized moderate to severe chronic periodontitis with presence of at least one site in each quadrant with a probing depth ≥5 mm were recruited. In a split mouth study design, two quadrants were randomly allocated to the SRP and ozone therapy and the remaining two quadrants to SRP and CHX therapy. Plaque index (PI), Gingival index (GI), probing depth (PD), clinical attachment loss (CAL) were assessed. Subgingival plaque samples were obtained for assessment of Aggregatibacter actinomycetemcomitans (Aa) and Porphyromonas gingivalis (Pg). Results Both groups demonstrated significant intragroup reduction in PI, GI, PD, CAL, Pg count and Aa count from baseline to 3 months follow-up. There were no significant differences between two groups for any of the parameters. Conclusion Ozonated olive oil can be used as an adjunctive subgingival irrigant in patients with chronic periodontitis.

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