The Inverse Relation between Risks and Benefits: The Role of Affect and Expertise

2014 ◽  
Author(s):  
Joanna Sokolowska ◽  
P. Sleboda
Risk Analysis ◽  
2015 ◽  
Vol 35 (7) ◽  
pp. 1252-1267 ◽  
Author(s):  
Joanna Sokolowska ◽  
Patrycja Sleboda

2021 ◽  
Vol 14 (3) ◽  
pp. e236892
Author(s):  
Mark Brahier ◽  
Rhanika Neuda ◽  
William Davis ◽  
Rita Poon

Medical tourism is the pursuit of more affordable surgeries; however, this comes at the risk of suboptimal standards and potential for life-threatening complications. In this case, we describe the diagnostic challenge of cytomegalovirus (CMV) pneumonia in a 40-year-old woman who experienced wound dehiscence and subsequent blood transfusion-transmitted CMV as complications of liposuction in the Dominican Republic. We explore the role of histopathology in the diagnosis of disseminated CMV, discuss the underlying aetiology of CMV pneumonia in this patient and weigh the risks and benefits of initiating antiviral therapy in an immunocompetent patient with CMV disease.


2021 ◽  
pp. 10.1212/CPJ.0000000000001034
Author(s):  
Paul J. Ford ◽  
Robert J. Fox ◽  
Mary Beth Mercer ◽  
Stacey S. Cofield

Abstract:Objective:To assess perceptions and opinions about the FDA approval process for disease modifying therapies (DMT) in people living with multiple sclerosis (MS).Methods:People living with MS were invited to complete a web-based survey of their perceptions of the FDA role and process for approval of MS medications. The survey asked about the role of the FDA, factors involved in the approval process, which voices should represent those with MS in deliberations about drug approval, and the level of comfort with uncertain safety of newly-approved therapies.Results:3533 respondents met inclusion criteria for data analysis. Most respondents appeared to understand the role of the FDA, although only half understood a fundamental FDA role: balancing the risks and benefits when considering drug approval. Significant differences were observed in many areas between those who have and have not tried DMTs. Comfort with uncertainty was associated with several factors relating to side effects and benefits thought important for the FDA to consider. Most respondents reported that people who participated in the medication’s clinical trial were particularly able to represent people living with MS.Conclusion:Perceptions regarding the FDA and views of who should represent people living with MS varied between those who have and have not tried DMT. There is variability in personal values that should be recognized and taken into account when considering regulatory responsibilities. Interventions are needed to address educational gaps regarding the mission and trustworthiness of the FDA as an oversight body.


Author(s):  
Johan Magnusson

This article addresses the role of the professional analysts as actors within the field of IT Governance. Through a content analysis of over 400 reports from the largest commercial research firm, instances of normative statements are identified and analyzed. With the intended target group of the reports being Chief Information Officers, the findings show that the content of IT Governance has changed during the last three years. This is discussed in relation to the role that professional analysts play in an ongoing construction of IT Governance. The article concludes by identifying possible risks and benefits involved in using professional analysts as sources for best-practice, as well as calling for a more practice-based definition of IT Governance.


2019 ◽  
Vol 15 (5) ◽  
pp. 216-222
Author(s):  
Nicola Daykin

This article discusses the history of natalizumab (Tysabri), the first monoclonal antibody used to treat multiple sclerosis. It reviews how the medication's difficult beginnings and controversial past have changed how this treatment is monitored. The article looks at the role of clinicians in maintaining patient safety, the benefits and risk profile of this treatment and ways of optimising practice to provide gold standard nationalised natalizumab services throughout the UK.


2019 ◽  
Vol 1 (8) ◽  
pp. 382-387
Author(s):  
Nicola Daykin

This article discusses the history of natalizumab (Tysabri), the first monoclonal antibody used to treat multiple sclerosis. It reviews how the drug's difficult beginnings and controversial past has changed the treatment is monitored treatment. The article looks at the role of clinicians in maintaining patient safety, the benefits and risk profile of this treatment, and ways of optimising practice to provide gold standard nationalised natalizumab services throughout the UK.


1986 ◽  
Vol 3 (1) ◽  
pp. 35-57
Author(s):  
Susan J. Coram ◽  
Michael Mangum

The large number of diabetic individuals, children and adults, and the potential problems that may arise in a fitness setting calls for a better understanding of the diabetic state. This review is therefore intended to stimulate an awareness of the complexity of the diabetic state and to emphasize the beneficial and potential hazardous effects of exercise. An overview is provided to orient the reader to basic concepts concerning diabetes. A variety of topics related to exercise and the diabetic are then presented. These include the metabolic benefits from exercise, exercise and coronary heart disease risk factors, factors influencing decreased exercise performance in diabetics, hypoglycemia and ketoacidosis, preliminary considerations and precautions for diabetic participants, and the role of education and self-discipline in diabetic control. Finally, practical guidelines for the diabetic and the physical educator are suggested.


2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Katherine M. Robinson ◽  
Adam K. Dubé

Current models of strategy choice do not account for children's attitudes towards different problem solving strategies. Grade 2, 3, and 4 students solved three sets of three-term addition problems. On inversion problems (e.g., 4 + 8 − 8), if children understand the inverse relation between the operations, no calculations are required. On associativity problems (e.g., 5 + 27 − 23), if children understand the associative relation between the operations, problem solving can be facilitated by performing subtraction before addition. A brief intervention involving demonstrations of different problem solving strategies followed the first problem set. Shortcut use increased after the intervention, particularly for students who preferred shortcuts to the left-to-right algorithm. In the third set, children were given transfer problems (e.g., 8 + 4 − 8, 4 − 8 + 8, 27 + 5 − 23). Shortcut use was similar to first set suggesting that transfer did occur. That shortcut use increased the most for students who had positive attitudes about the shortcuts suggests that attitudes have important implications for subsequent arithmetic performance.


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