scholarly journals The Relationship between Platelet Count and Host Gut Microbiota: A Population-Based Retrospective Cross-Sectional Study

2018 ◽  
Author(s):  
Hee-Young Yoon ◽  
Han-Na Kim ◽  
Su Hwan Lee ◽  
Soo Jung Kim ◽  
Yoosoo Chang ◽  
...  



2005 ◽  
Vol 29 (4) ◽  
pp. 357-362 ◽  
Author(s):  
Ana Estela Haddad ◽  
Maria Salete Nahás Pires Correa

The objective of this study is to determine the correlation between the number of erupted primary teeth, the age, sex and the somatic measures of weight and height (length) in a Brazilian population based cross sectional study. A systematic sampling was used. Complete and consistent data were obtained from 870 of a total of 908 children from birth to 36 months of age. Statistical analysis comprised a multiple regression equation, where the number of erupted primary teeth was modeled as the dependent variable and the initial specification included the following independent variables: age, sex, birth-length, birth-weight, weight and length measured at the examination of the child. Results showed that in this study, 86% of the variation of the number of erupted primary teeth was explained by age and height of children (p<0.001). Age and height showed a stronger correlation with the number of erupted primary teeth than all the tested variables together. It was concluded that primary teeth eruption is highly influenced by age and height (length) of the child. Using the best regression equation found, a chart was constructed where the variation of the number of erupted primary teeth is given according to age and height of the child.



2019 ◽  
Vol 15 ◽  
pp. P1349-P1350
Author(s):  
Ningwei Hu ◽  
Ling Gao ◽  
Yu Jiang ◽  
Shan Wei ◽  
Suhang Shang ◽  
...  




Molecules ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 1667
Author(s):  
Takuya Fukuda ◽  
Masahide Hamaguchi ◽  
Takafumi Osaka ◽  
Yoshitaka Hashimoto ◽  
Emi Ushigome ◽  
...  

Thrombopoietin (THPO) is a circulatory cytokine that plays an important role in platelet production. The presence of anti-THPO antibody relates to thrombocytopenia and is rarely seen in hematopoietic and autoimmune diseases. To date, there had been no reports that focused on the anti-THPO antibody in patients with type 2 diabetes mellitus (T2DM). To evaluate prevalence of the anti-THPO antibody in patients with T2DM and the relationship between anti-THPO antibody and platelet count, a cross-sectional study was performed on 82 patients with T2DM. The anti-THPO antibody was measured by ELISA using preserved sera and detected in 13 patients. The average platelet count was significantly lower in patients with the anti-THPO antibody than in those without the anti-THPO antibody. Multivariate linear regression analyses showed a significant relationship between the anti-THPO antibody and platelet count, after adjusting for other variables. To our best knowledge, this was the first report on the effect of the anti-THPO antibody on platelet count in patients with T2DM. Further investigation is needed to validate the prevalence and pathological significance of the anti-THPO antibody in patients with T2DM.



Author(s):  
Ahmed Arafa ◽  
Alshimaa Mostafa ◽  
Yasser Khamis

AbstractBackgroundAcne and menstrual symptoms are highly prevalent among young women. Since both acne and menstrual symptoms have similar hormonal pathogenesis, it is highly suggested that the two conditions are associated. Herein, we conducted this study to assess the relationship between acne and menstrual symptoms among young women.Subjects and methodsIn this population-based cross-sectional study, a multi-stage random sampling approach was used to include 3065 young women (18–25 years) from Egypt. Women were interviewed for their socio-demographic characteristics, gynecological history, premenstrual and menstrual symptoms, and history of acne and perimenstrual acne flare during the past 6 months.ResultsThe mean age of women was 21.5 ± 2.2 and their age of menarche was 13.1 ± 1.5 years. During the previous 6 months, 44.8% of participants had acne. After adjusting for socio-demographic and gynecological characteristics, acne was associated with most menstrual symptoms with odds ratios (ORs) and 95% confidence intervals (CIs) as follows: [premenstrual symptoms: 1.23 (1.05–1.44) for irritation or nervousness, 1.45 (1.24–1.68) for fatigue, 1.37 (1.15–1.62) for breast tenderness, 1.48 (1.21–1.80) for abdominal bloating, and 1.36 (1.11–1.66) for nausea or vomiting], [menstrual symptoms: 1.63 (1.19–2.23) for dysmenorrhea and 1.24 (1.06–1.45) for dysmenorrhea requiring drugs], and [symptoms severity: 1.44 (1.24–1.68) for missing events and 1.38 (1.16–1.64) for medical consultation]. Of acne patients, 56.7% reported perimenstrual acne flare: 58.5% before menses, 35% during menses, and 6.5% after menses.ConclusionThis study supports the concept that acne is associated with menstrual symptoms. Physicians should consider screening for menstrual symptoms among young women with acne.





2020 ◽  
Vol 32 (3) ◽  
pp. 379-390.e3 ◽  
Author(s):  
Hao Wu ◽  
Valentina Tremaroli ◽  
Caroline Schmidt ◽  
Annika Lundqvist ◽  
Lisa M. Olsson ◽  
...  


2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Dandan Sun ◽  
Quanliang Wang ◽  
Jie Kang ◽  
Jie Zhou ◽  
Ruijuan Qian ◽  
...  

Background. The risk of cognitive impairment in patients with atrial fibrillation is significantly increased. Its occurrence may be related to blood hypercoagulable state and immune inflammatory reaction. Platelets can mediate immune inflammatory response, but there is no evidence about the relationship between platelet count and cognitive function in patients with atrial fibrillation. Purpose. To explore whether there is a certain correlation between platelet count and cognitive function in patients with atrial fibrillation. Methods. A cross-sectional study was conducted in a single center in China, including 254 patients with atrial fibrillation. Cognitive function assessment and clinical and laboratory examinations were performed on all participants. After adjusting the related confounding factors, the relationship between platelet count and cognitive function was analyzed. Results. A total of 254 subjects with an average age of 59.71 ± 11.14 years were included. The average platelet count was 208.15 ± 68.30, and the average score of cognitive function was 19.29 ± 6.78. Result of fully adjusted binary logistic regression showed platelet count was negatively associated with the cognitive function score after adjusting confounders (hazard ratio (HR) = 0.000, 95%CI −0.01, 0.01). A nonlinear relationship was detected between platelet count and the cognitive function score, whose point was 230. The effect sizes and the confidence intervals of the left and right sides of the inflection point were 0.03 (0.01–0.05, P for nonlinearity = 0.011) and −0.03 (−0.05–0.00, P for nonlinearity = 0.023), respectively. Conclusion. Platelets have a nonlinear relationship with cognitive function in patients with atrial fibrillation. This finding suggests that, in patients with atrial fibrillation, platelets should be maintained at about 230.



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