scholarly journals Pre-Exposure Prophylaxis (PrEP) in the Prevention of HIV: Strategies, Target Populations and Upcoming Treatments

2020 ◽  
Vol Volume 12 ◽  
pp. 283-293
Author(s):  
Ayşe Elif Özdener-Poyraz ◽  
Malgorzata Slugocki ◽  
Julie Kalabalik-Hoganson ◽  
Jayoung Han
Keyword(s):  
Target Populations ◽  
Exposure Prophylaxis ◽  
Prevention Of Hiv

scholarly journals The review of pre-exposure prophylaxis (PreP) for HIV prevention

2014 ◽  
Vol 11 (1) ◽  
pp. 50-59
Author(s):  
Meriam Caboral Stevens ◽  
Godfrey Aneke ◽  
Andrew Neplock
Keyword(s):  
Hiv Prevention ◽  
Global Health ◽  
Hiv Infection ◽  
Condom Use ◽  
Biomedical Research ◽  
Prevention Strategies ◽  
Global Health Issue ◽  
Exposure Prophylaxis ◽  
Current Guidelines ◽  
Prevention Of Hiv

Human lmmunodeficiency Virus (HlV) epidemic continues to represent a major global health issue. Today, there are several tools available to prevent the spread of HIV infection. However, there are several constraints to the current prevention strategies including low condom use, low acceptance of testing, low awareness of vulnerability and more emphasis on treatment. Prevention strategy is redirected towards reducing acquisition of HIV. Pre-exposure prophylaxis or PrEP is the latest groundbreaking innovation in biomedical research in the prevention of HIV transmission.The purpose of this paper is to review preex ding the current guidelines in the use of PreP.

scholarly journals Challenges and opportunities for oral pre-exposure prophylaxis in the prevention of HIV infection: where are we in Europe?

BMC Medicine ◽  
2013 ◽  
Vol 11 (1) ◽  
Author(s):  
Jean-Michel Molina ◽  
Claire Pintado ◽  
Caroline Gatey ◽  
Diane Ponscarme ◽  
Pierre Charbonneau ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Challenges And Opportunities ◽  
Exposure Prophylaxis ◽  
Prevention Of Hiv

HIV Transmission Prevention

2017 ◽  
Author(s):  
Carolyn Chu ◽  
Christopher M. Bositis
Keyword(s):  
Hiv Transmission ◽  
Hiv Infections ◽  
Risk Groups ◽  
Antiviral Drugs ◽  
Antiretroviral Drugs ◽  
Post Exposure Prophylaxis ◽  
Needle Exchange Programs ◽  
Hiv Acquisition ◽  
Exposure Prophylaxis ◽  
Prevention Of Hiv

The prevention of HIV transmission involves a number of behavioral, structural, and biomedical interventions. Behavioral methods include education about sexual health, drug use, and risk reduction, as well as specific messages for at-risk populations who are HIV positive. Needle exchange programs and consistent use of condoms have proven effective for prevention of HIV infection. Post-exposure prophylaxis against HIV with antiviral drugs is often recommended in occupational health care and non-occupational settings. Voluntary male circumcision also reduces the risk of HIV acquisition. The treatment of pregnant women who are HIV infected can effectively eliminate mother-to-child transmission of the virus. Recently, the use of antiretroviral drugs for pre-exposure prophylaxis has proven highly effective in preventing HIV infections in high-risk groups including men who have sex with men. Promising therapies that likely will be available in the future include injectable antiviral drugs, vaginal microbicides, and HIV vaccines.

Antiretroviral Therapy in Children and Newborns

2017 ◽  
Author(s):  
Karin Nielsen-Saines
Keyword(s):  
Hiv Infection ◽  
Pediatric Hiv ◽  
Post Exposure Prophylaxis ◽  
Older Children ◽  
Viral Reservoirs ◽  
Young Infants ◽  
Exposure Prophylaxis ◽  
Prevention Of Hiv ◽  
Infants And Young Children ◽  
Early Antiretroviral Treatment

HIV-infected infants and children have a different, more progressive disease course compared to that of adults given that early infection leads to sustained, high-magnitude viremia with significant seeding of reservoirs in the first months of life. Early diagnosis of HIV infection is pivotal in the management of infants and prevention of HIV-associated morbidity and mortality. The availability of potent pediatric antiretroviral formulations encompassing different classes of drugs for infected infants and young children is limited. Significant advancements have been achieved in the area of infant post-exposure prophylaxis. Early antiretroviral treatment is still the mainstay of pediatric HIV infection, particularly for infants younger than age 12 months, but it is also highly recommended for older children. Early treatment of young infants diagnosed soon after birth appears to be the best approach to reduce the seeding of viral reservoirs and potentially attain prolonged periods of HIV remission off antiretrovirals.

Immunocompromised patients, including HIV-positive patients

2016 ◽  
Author(s):  
Dr Sanjay Bhagani ◽  
Dr Nicholas Easom ◽  
Dr Sanjay Bhagani ◽  
Dr Nicholas Easom ◽  
Dr Nicholas Easom
Keyword(s):  
Organ Transplant ◽  
Immune Dysfunction ◽  
Solid Organ Transplant ◽  
Hiv Positive ◽  
Post Exposure Prophylaxis ◽  
Solid Organ ◽  
Immunocompromised Patients ◽  
Secondary Immunodeficiency ◽  
Exposure Prophylaxis ◽  
Prevention Of Hiv

Chapter 13 discusses immunocompromised patients, including HIV-positive patients, HIV and other causes of immunodeficiency, infections in the HIV-infected patient, post-exposure prophylaxis (PEP) for prevention of HIV infection, non-HIV causes of immunodeficiency, secondary immunodeficiency in malignancy or post-chemotherapy, immune dysfunction and systemic illness, solid organ transplant, and immunosuppressive therapy.

Unsupervised PrEP in routine practice: a new challenge?

2019 ◽  
Vol 30 (7) ◽  
pp. 715-717
Author(s):  
Hélène Laroche ◽  
Caroline Lions ◽  
Olivia Zaegel-Faucher ◽  
Catherine Tamalet ◽  
Isabelle Poizot-Martin
Keyword(s):  
Viral Load ◽  
Hiv Infection ◽  
Western Blot ◽  
Plasma Viral Load ◽  
Routine Practice ◽  
Substantial Risk ◽  
Sex With Men ◽  
Exposure Prophylaxis ◽  
Prevention Option ◽  
Prevention Of Hiv

Pre-exposure prophylaxis (PrEP) for the prevention of HIV infection with 300 mg daily tenofovir co-formulated with 200 mg emtricitabine is recommended as one prevention option for people who are at substantial risk of acquiring an HIV infection. We report the case of a 28-year-old man who has sex with men and who was referred to our unit for a primary HIV infection with positive p18, p24 and gp160 bands on Western blot analysis but with a low HIV plasma viral load. Although HIV misdiagnosis should always be considered in cases of atypical seroconversion pattern with a low viral burden, unsupervised PrEP should be systematically investigated.

scholarly journals Oral Pre-Exposure Prophylaxis (PrEP) for Prevention of HIV in Serodiscordant Heterosexual Couples in the United States: Opportunities and Challenges

2014 ◽  
Vol 28 (9) ◽  
pp. 462-474 ◽  
Author(s):  
James M. McMahon ◽  
Julie E. Myers ◽  
Ann E. Kurth ◽  
Stephanie E. Cohen ◽  
Sharon B. Mannheimer ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Heterosexual Couples ◽  
Exposure Prophylaxis ◽  
Prevention Of Hiv
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