RETROSPECTIVE ANALYSIS OF PRIMARY EXTRANODAL NON HODGKINS LYMPHOMA- 3 YEARS STUDY AT A TERTIARY CARE INSTITUTE.

Background: Non Hodgkins lymphoma is the most prevalent hematopoietic neoplasm, representing approximately 4% of all cancer diagnoses and ranking seventh in frequency among all cancers. Most of the data that we have is of west and data pertaining to Indian subcontinent is lacking. The aim of this study was to study clinical profile, prognostication, and assess treatment outcome in DLBCL patients in a tertiary care hospital.Methods: 100 patients of DLBCL reporting to a tertiary care hospital between 2013 to 2016 were chosen for the study. All patients were subjected to routine investigation and specialized investigation including bone marrow examination and Positron emission tomography. Patients were treated with standard treatment protocol and their response to treatment were assessed.Results: Study revealed male predominance with median age of onset was 45.6. Anorexia was the most common symptom. Lymphadenopathy was the most common sign. Bone marrow involvement and anemia commensurate each other. Only16% cases presented in IPI score 4 and 5. Complete remission achieved with treatment in stage l and ll disease were beyond 90% and steep decline in complete remission with treatment was noted in stage lll and lV (~70%). 76% patients with DLBCL showed CR, 12.5% showed PR.Conclusions: The present study revealed male preponderance with relatively early age of onset compared to western population. B- cell lymphoma (DLBCL) constituted maximum number of NHL cases (89%). We have found a higher proportion of B cell subtype as compared to other Indian studies, at the same time it corroborated with the findings of western studies. Complete remission achieved with treatment in stage l and ll disease were beyond 90% and steep decline in complete remission with treatment was noted in stage lll and lV (~70%).

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Engraftment Syndrome: A Retrospective Analysis of the Experience at a Tertiary Care Institute

Clinical Hematology International ◽

10.2991/chi.d.190504.001 ◽

2019 ◽

Author(s):

Raja Pramanik ◽

Harish Kancharla ◽

Sameer Bakhshi ◽

Atul Sharma ◽

Ajay Gogia ◽

...

Keyword(s):

Retrospective Analysis ◽

Tertiary Care ◽

Care Institute ◽

Engraftment Syndrome

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CLINICO-PATHOLOGICAL FEATURES AND MANAGEMENT OF CHILDREN WITH NON-HODGKINS LYMPHOMA IN PAKISTAN: A RETROSPECTIVE ANALYSIS. 85

Pediatric Research ◽

10.1203/00006450-199705000-00104 ◽

1997 ◽

Vol 41 (5) ◽

pp. 760-760

Author(s):

Zeba Aziz ◽

Sobia Qazi

Keyword(s):

Retrospective Analysis ◽

Pathological Features ◽

Hodgkins Lymphoma ◽

Non Hodgkins Lymphoma

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Unusual presentations and associations of hyper IgE Syndrome: Retrospective analysis of ten cases at tertiary care institute – With review of indian published reports

Indian Journal of Paediatric Dermatology ◽

10.4103/ijpd.ijpd_144_16 ◽

2018 ◽

Vol 19 (1) ◽

pp. 31

Author(s):

JignaK Padhiyar ◽

NayanH Patel ◽

YogeshB Shah ◽

TrushaP Gajjar ◽

MansiD Buch

Keyword(s):

Retrospective Analysis ◽

Tertiary Care ◽

Hyper Ige Syndrome ◽

Care Institute

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Trends in the profile of non hodgkins lymphoma in North and South India: a study from two tertiary care hospitals in India

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20201331 ◽

2020 ◽

Vol 8 (4) ◽

pp. 1391

Author(s):

Rahul Sud ◽

Kishore Kumar ◽

A. P. Dubey ◽

Sagar Bhagat

Keyword(s):

T Cell ◽

South India ◽

Cell Lymphoma ◽

Tertiary Care ◽

B Cell Lymphoma ◽

Age Group ◽

Hodgkins Lymphoma ◽

Army Hospital ◽

Non Hodgkins Lymphoma ◽

Hodgkin's Lymphomas

Background: A number of environmental and chemical factors have been thought to been implicated in the occurrence of Non-Hodgkin’s Lymphomas (NHLs).To fill the knowledge gap in various aspect of the disease, this study was undertaken at this tertiary care centre in Delhi and Bangalore.Methods: This was a prospective observational study conducted in two defenses medical centre in India among patients of Non Hodgkins Lymphoma, registered at Command hospital Airforce Bangalore and Army Hospital (Research and Referral), New Delhi, between March 2016 and March 2019.Results: The disease showed a bimodal onset in both centres with 26 (26%) and 24 (24%) cases occurring in the age group of 31-40 years and 24 (24%) and 25 (25%) cases occurring in the age group of >60 years at CHAF (B) and AH (RR) respectively. B cell Lymphoma was the most common type of NHL seen in 85% and 89% patients, whereas T-cell lymphomas constituted 13% and 11% at CHAF (B) and AH (RR). 32(32%) patients presented with an Ann Arbor Stage 1 or 2 disease whereas 68(68%) patients were with Stage 3 or 4 disease at both the centers. IPI score was ≥3 in 45 % and 43% patients.Conclusions: NHL in India is a homogeneous and uniform disease. But there was increased detection of hepatosplenomegaly and associated hepatitis B/C in the southern part of India. Also, the occurrence of Cutaneous T cell lymphoma was only seen in the south India centre. The early stage NHLs has better survival and increase chance of complete response.

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