scholarly journals Clinical guidelines «Children with diabetes mellitus type 1, 2020”: what a pediatrician needs to know

2021 ◽  
Vol 66 (5) ◽  
pp. 109-117
Author(s):  
I. L. Alimova
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Medical Care ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Guidelines ◽  
Diabetes Mellitus Type 1 ◽  
Pediatric Endocrinology ◽  
Treatment Organization ◽  
Quality Of Medical Care

A group of experts, leading Russian specialists in the field of pediatric endocrinology prepared updated clinical guidelines for the diagnosis and treatment of type 1 diabetes mellitus in children. The article presents the main provisions of clinical guidelines for diagnosis and differential diagnosis, treatment, organization of medical care, specific and acute complications in children with type 1 diabetes mellitus. These clinical recommendations and concerted actions in practical work will allow pediatricians and pediatric endocrinologists to improve the diagnosis, treatment and quality of medical care for children with type 1 diabetes.

scholarly journals Dynamics of incidence and prevalence of type 1 diabetes mellitus in children in the Russian Federation (2001-2007)

2009 ◽  
Vol 12 (3) ◽  
pp. 23-27
Author(s):  
Tatiana Yur'evna Shiryaeva ◽  
Ekaterina Andreevna Andrianova ◽  
Yury Ivanovich Suntsov
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Far East ◽  
Secondary Source ◽  
Sources Of Information ◽  
Pediatric Endocrinology ◽  
Type 1 Dm ◽  
Epidemiological Characteristics

Aim. To study dynamics of main epidemiological characteristics (incidence and prevalence) of type 1 diabetes mellitus (DM) in children in theRussian Federation (RF) and its Federal districts (FD) in 2001-2007. Materials and methods. Analysis of main epidemiological characteristics (incidence, prevalence, mortality) of type 1 DM in children of RF has beenunderway in the Institute of Pediatric Endocrinology, ERC, since 2001 based on results of questionnaire studies. The questionnaires regularly distributedamong Health Committees of RF subjects (primary sources of information) are designed to collect data on the size, age and sex compositionof childrens populations affected by DM1 and the number of newly diagnosed cases as per the end of each reporting year. The data obtainedare compared with those stored in the State Diabetes Registry (secondary source of information). Results. Major trends in the dynamics of epidemiological characteristics of type 1 DM in children of RF are similar to those worldwide. Mean annualgrowth rate is 2,8%. The incidence of DM1 remains highest in the North-West FD (15,66 per 100 000 children) followed by Central andVolga FDs (12,82 and 10,6 respectively) where its is close to the average value FDr RF (11,01). The incidence of DM1 continues to decrease in theSouthern FD (6,61% per year) and undergoes up-and-down fluctuations in Ural and Siberian FDs. It steadily grows in the Far East FD. TheNorth-South gradient of DM1 morbidity across the territory of RF has persisted during the study period. Conclusion. Monitoring main epidemiological characteristics of type 1 diabetes mellitus in children of RF is an integral component of the organizationof medical and preventive aid to these patients that creates a basis for predicting morbidity, planning measures for its control, and improvinggeneral quality of healthcare provided to diabetic children

scholarly journals Effectiveness of a nutrition education package on glycaemic control among children with type 1 diabetes mellitus aged 3-14 years in Uganda: study protocol for a cluster-randomized trial

2020 ◽  
Author(s):  
NICHOLAS BARI NDAHURA ◽  
JUDITH MUNGA ◽  
JUDITH KIMIYWE ◽  
EZEKIEL MUPERE
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Glycaemic Control ◽  
Medical Care ◽  
Type 1 Diabetes Mellitus ◽  
Nutrition Education ◽  
Control Group ◽  
Routine Medical Care ◽  
Level Of Knowledge

Introduction: Inadequate dietary management practices among children with type 1 diabetes mellitus (T1DM) often result in preventable complications, disability, and premature deaths, and yet strict glycaemic control can help reduce the long-term complications. Furthermore, parental caregiving has also been shown to have an impact on glycaemic control and yet often a gap exists between recommended care and provided care, resulting in failure of children with T1DM meeting their treatment targets. In Uganda, no published study has been conducted to find out if nutrition education has an effect on glycaemic control and caregivers level of knowledge on general and diabetes-specific nutrition for children with T1DM. Methods: The study will be a cluster randomised controlled trial with 10 health facilities randomised to control or intervention at a ratio of 1:1. A total of 100 caregiver-child pairs will be recruited. The participants in the control group will continue to receive routine medical care, while those in the intervention group will receive routine medical care and a nutrition education package. The primary outcome is glycated hemoglobin (HbA1c) values. Secondary outcomes will be caregivers level of knowledge on general and diabetes-specific nutrition knowledge, childrens dietary diversity score and childrens mean intake of energy, protein, and fat. Discussion: The findings of this study will be used in improving nutrition education in T1DM among children attending diabetes clinics in Uganda. Trial registration number: The trial is registered with The Pan African Clinical Trials Registry (PACTR201902548129842).

scholarly journals Evaluation of Vascular Endothelial Function in Children with Type 1 Diabetes Mellitus

2021 ◽  
Vol 10 (21) ◽  
pp. 5065
Author(s):  
Karolina Nocuń-Wasilewska ◽  
Danuta Zwolińska ◽  
Agnieszka Zubkiewicz-Kucharska ◽  
Dorota Polak-Jonkisz
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Endothelial Dysfunction ◽  
Type 1 Diabetes Mellitus ◽  
Diabetes Mellitus Type 1 ◽  
Vascular Endothelial ◽  
Healthy Controls ◽  
Linear Correlations ◽  
Pai 1

Diabetic kidney disease belongs to the major complications of diabetes mellitus. Here, hyperglycaemia is a key metabolic factor that causes endothelial dysfunction and vascular changes within the renal glomerulus. The aim of the present study was to assess the function of the vascular endothelium in children with type 1 diabetes mellitus (type 1 diabetes) by measuring selected endothelial lesion markers in blood serum. The selected markers of endothelial lesions (sVCAM-1, sICAM-1, sE-SELECTIN, PAI-1, ADMA and RAGE) were assayed by the immunoenzymatic ELISA method. The study involved 66 patients (age: 5–18 years) with type 1 diabetes and 21 healthy controls (age: 5–16 years). In the type 1 diabetes patients, significantly higher concentrations of all of the assayed markers were observed compared to the healthy controls (p < 0.001). All of the evaluated markers positively correlated with the disease duration, the age, and BMI of the patients, while only PAI-1 and sE-SELECTIN were characteristic of linear correlations with the estimated glomerular filtration rate (eGFR). It can be concluded that endothelial inflammatory disease occurs in the early stages of type 1 diabetes mellitus in children. The correlations between PAI-1, sE-SELECTIN, and eGFR suggest an advantage of these markers over other markers of endothelial dysfunction as prognostic factors for kidney dysfunction in children with type 1 diabetes.

scholarly journals Variability of glycemia and cognitive impairment in patients with diabetes mellitus type 1.

2018 ◽  
Vol 96 (8) ◽  
pp. 741-745
Author(s):  
Yu. G. Samoylova ◽  
M. V. Matveeva ◽  
N. G. Zhukova ◽  
M. A. Rokank
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Cognitive Impairment ◽  
Type 1 Diabetes Mellitus ◽  
Cognitive Functions ◽  
Risk Index ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type ◽  
The Relationship

Diabetes mellitus type 1 is associated with impaired cognitive function. Based on the results of systematic reviews and meta-analyzes, the most likely modifiable risk factor is the degree of metabolic control, in particular the variability of glycemia. Aims: to determine the influence of the variability of glycemia on cognitive functions in patients with type 1 diabetes mellitus. Material and methods. Design-observational, one-stage, cross-sectional research. We examined 30 patients with type 1 diabetes mellitus who were divided into 2 groups: 1 group (main) with cognitive impairment, and 2 (control) with normal cognitive functions. All patients were screened for cognitive functions using the Montreal scale (MoCa test). For the diagnosis of fluctuations in glucose level, continuous monitoring of glycemia was carried out using the iPro-2 device (Medtronic, USA): mean glycemic mean (MEAN), standard deviation (SD), mean amplitude of glycemic fluctuation (MAGE), long-term glycemic index (CONGA) Glycemia lability index (LI), hypoglycemia risk index (LBGI), hyperglycemia risk index (HBGI), mean hourly rate of glycemic change (MAG). Results. The study revealed that in patients with type 1 diabetes mellitus, cognitive impairment was dominated by a violation of constructive praxis, memory and attention. Recorded a significant difference in MEAN, SD, CONGA, Gindex, LBGI, HBGI, MAGE, Mvalue and MAG. Correlation analysis revealed the relationship of cognitive impairments with the level of HbA1c, as well as the variability parameters MEAN, SD, CONGA, Gindex, LBGI, HBGI, MAGE, Mvalue, MAG. Conclusions. The relationship between the variability of glycemia and cognitive impairment was registered in patients with type 1 diabetes mellitus

scholarly journals Diabetes Mellitus Type-1 and Psychosocial Intervention to Improve Quality of Life

2021 ◽  
Vol 1 (4) ◽  
pp. 80-85
Author(s):  
Sarah Amalia
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type ◽  
Self Control ◽  
Comprehensive Treatment

Type 1 diabetes mellitus is the most common chronic endocrine pathology among children. Data from the Indonesian Pediatric Association (IDAI) states that the incidence of DM in children aged 0-18 years has increased by 700% over a period of 10 years. Treatment includes diet, physical activity, insulin medication, and proper self-control. The necessary changes in habits and lifestyles can lead to psychosocial problems, including anxiety, depression and eating disorders. Subsequently, the child or adolescent and his or her family group may move into new balance characterized by good self-control and adherence to treatment, or deepen individual and group disorders which may reappear, especially in adolescence. The comprehensive treatment of type 1 diabetes mellitus requires addressing these aspects through multidisciplinary teams which include medical and psychosocial professionals. This review analyses the main aspects related to the psychosocial impact of diabetes mellitus type 1 among children, adolescents and their families mental. A substantial amount of behavioral science research has demonstrated that psychosocial factors play an integral role in the management of diabetes in both children and adults. Research has also shown how psychosocial therapies that can improve regimen adherence, glycemic control, psychosocial functioning, and quality of life.

scholarly journals Characteristics of cognitive function in patients with diabetes mellitus type 1 younger depending transferred hypoglycemic conditions

2017 ◽  
pp. 17-21
Author(s):  
N. Zherdоva ◽  
B. Mankovsky
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Type 1 Diabetes Mellitus ◽  
Depression Scale ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type ◽  
Patients With Diabetes

Many studies focus on the effect of compensation of diabetes, glucose-lowering therapy of choice, the influence of cardio - vascular diseases in the state of cognition. At the same time, not enough attention is paid to cognitive impairment in patients with type 1 diabetes mellitus, especially young people. The aim of our study was to investigate the prognostic factors of dementia in patients with type 1 diabetes mellitus are younger. 33 patients were examined with type 1 diabetes and 10 people in the control group. Of the 33 patients with diabetes, 21 people had hypoglycemia in the last 3 months and 12 without hypoglycemic states. To identify depression used two questionnaires: Centre for Epidemiologic Studies Depression Scale (CES-D) and the Hospital Anxiety and Depression Scale (HAD). Evaluation of cognitive impairment was conducted using the following methods: The test "5 words", sample Schulte, the scale of assessment of mental status ( MMSE), test battery on the frontal dysfunction (BLD), evaluation of test o’clock. To reveal the 10-year risk of dementia patients used the scale which was developed by a team of researchers at Utrecht University Medical Rudolf Magnus. In patients with type 1 diabetes with hypoglycemia marked deterioration in cognitive function, according to the neuropsychological tests, namely the BLD and MMSE compared with  patient without hypoglycemia. The risk of developing dementia over 10 years in patients with diabetes mellitus type 1 young up 2.2 times compared with patients without hypoglycemia. Hypoglycemic state is the main risk factor that leads to the development of cognitive impairment, and this is a factor which can be influenced by insulin properly selected.

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