scholarly journals Role of Plasma Von Willebrand Factor-Antigen in predicting the presence of Esophageal Varices and occurrence of its bleeding in cirrhotic patients

2019 ◽  
Vol 9 (2) ◽  
pp. 139-149
Author(s):  
Mona Abdelmaksoud ◽  
Amal Jouda ◽  
Talaat Fathy ◽  
Ahmad Ibrahim ◽  
Ahmad Soliman ◽  
...  
Keyword(s):  
Von Willebrand Factor ◽  
Esophageal Varices ◽  
Von Willebrand Factor Antigen ◽  
Cirrhotic Patients ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Factor Antigen

scholarly journals Role of plasma von Willebrand factor antigen in prediction of esophageal varices in pediatric and adolescent patients with portal hypertension

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lerine B. El Shazli ◽  
Dina A. Ragab ◽  
Karim A. Abdelhady ◽  
Asmaa W. Abdelaziz
Keyword(s):  
Portal Hypertension ◽  
Von Willebrand Factor ◽  
Esophageal Varices ◽  
Cross Sectional ◽  
Non Invasive ◽  
Von Willebrand Factor Antigen ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Factor Antigen

Abstract Background Ruptured esophageal varices (EVs) are a leading cause of death in Portal hypertension (PHT), it has been a big concern of research to screen EVs through non-invasive approaches. This study aimed to evaluate the role of plasma von Willebrand factor antigen (VWF-Ag) assay for early detection of EVs in patients with portal hypertension. This was a cross-sectional study, done on 47 portal hypertensive children and adolescents who were collected from the Pediatrics Hepatology Clinic, Children Hospital, Ain Shams University. All patients were subjected to comprehensive history taking, thorough clinical examination, routine investigations, abdominal ultrasound, upper GI endoscopy, and measurement of plasma VWF-Ag level. The patients were divided based on their endoscopic findings into two groups; a varices group which included 37 patients, and a non-varices group which included 10 patients. Results VWF-Ag rise significantly in patients with EVs, revealing a direct positive association with the degree of EVs. Conclusion The plasma VWF-Ag can be applied as a non-invasive evidence of the presence and grading of EVs.

scholarly journals Reliability of Plasma Von Willebrand Factor Antigen in Prediction of Esophageal Varices in Patients with Liver Cirrhosis

2015 ◽  
Vol 05 (06) ◽  
pp. 49-57
Author(s):  
Hasan Sedeek Mahmoud ◽  
Ali A. Ghweil ◽  
Shamardan E. Bazeed ◽  
Hanan M. Fayed ◽  
Mona M. Abdel Meguid
Keyword(s):  
Liver Cirrhosis ◽  
Von Willebrand Factor ◽  
Esophageal Varices ◽  
Von Willebrand Factor Antigen ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Factor Antigen

scholarly journals Plasma levels of von Willebrand factor antigen in acute bronchitis and in a normal population

1998 ◽  
Vol 92 (3) ◽  
pp. 395-400 ◽  
Author(s):  
D.A.R. Boldy ◽  
P.E. Short ◽  
P. Cowen ◽  
F.G.H. Hill ◽  
D.C. Chambers ◽  
...  
Keyword(s):  
Von Willebrand Factor ◽  
Plasma Levels ◽  
Normal Population ◽  
Acute Bronchitis ◽  
Von Willebrand Factor Antigen ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Factor Antigen

scholarly journals Assessment of Plasma von Willebrand factor antigen in non-metastatic Prostate Cancerpatients: across-sectional study of the Sudanese Population

2019 ◽  
Author(s):  
Mohammed Othman Hashim ◽  
Gad Allah Modawe ◽  
Ibrahim Khider Ibrahim
Keyword(s):  
Prostate Cancer ◽  
Von Willebrand Factor ◽  
Enzyme Linked Immunosorbent Assay ◽  
Sectional Study ◽  
High Concentration ◽  
Cross Sectional ◽  
Von Willebrand Factor Antigen ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Factor Antigen

Backgrounds: VonWillebrand disease (VWD) is reportedly the most common inherited bleeding disorder and can also arise as an acquired syndrome (AVWS). These disorders arise due to defects and/or deficiency of the plasma protein von Willebrand factor (VWF)..High plasma vWF concentrations have been reported in patients with various types of cancer, such as prostatic cancer.Metastasization may be associated with activation of haemostatic processes resulting in increased levels of circulating factor VIII-related antigen (FVIIIRAg) (von Willebrand factor antigen). Objective: To evaluate the status of VWF AginSudanese patients with Prostate Cancer attending RICK Methodology: This is a cross-sectional study carried out in Khartoum state at Khartoum oncology (RICK) hospital, during the period from April to June 2018, 45 samples were collected from patients with non-metastatic CA prostate, their ages ranged between 51 to 82 years. The vWF level was measured using Enzyme-linked immunosorbent assay (ELISA). Data were analyzed by the statistical package for social science (SPSS).   Results: Serology for vWF antigen was done for 45 cases of prostate cancer. According to the age, 2(8%) of patients with age 51-66 had a high concentration of VWF while 24(92%) had normal vWF antigen concentration; of those with age 67-82 years, 4(21%) had high vWF antigen and 15(79%) had normal antigen. Conclusion: The study revealedthat more than 80% of Sudanese patients withnon-metastatic prostate cancer have anormal concentration of VWF. Keywords: vWF, Prostate cancer, Age, ELISA

scholarly journals Predictors of Bleeding from Esophageal Varices: The Role of Factor VII and von Willebrand Factor (vWF)

2014 ◽  
Vol 04 (04) ◽  
pp. 152-158 ◽  
Author(s):  
Ali Abdelrahman Ghweil ◽  
Usama Ahmed Arafa ◽  
Ashraf Khodeary ◽  
Ahmed N. Salem
Keyword(s):  
Von Willebrand Factor ◽  
Esophageal Varices ◽  
Factor Vii ◽  
Von Willebrand ◽  
Willebrand Factor
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