Is Propionic acid a suitable model for autism?

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Heba Alla Elmalahy ◽  
elham Ali ◽  
Ali Abu Almaaty ◽  
Osama Abbas
Keyword(s):  
Propionic Acid ◽  
Suitable Model

Chemical modification of the bacterial wall to determine sites of metal deposition

1978 ◽  
Vol 36 (2) ◽  
pp. 350-351
Author(s):  
T. J. Beveridge
Keyword(s):  
Electron Scattering ◽  
Metal Salt ◽  
Metal Deposition ◽  
Suitable Model ◽  
X Ray Diffraction ◽  
Subtilis Cell ◽  
Thin Sections ◽  
X Ray ◽  
Section Data ◽  
Metal Impregnation

The Bacillus subtilis cell wall provides a protective sacculus about the vital constituents of the bacterium and consists of a collection of anionic hetero- and homopolymers which are mainly polysaccharidic. We recently demonstrated that unfixed walls were able to trap and retain substantial amounts of metal when suspended in aqueous metal salt solutions. These walls were briefly mixed with low concentration metal solutions (5mM for 10 min at 22°C), were well washed with deionized distilled water, and the quantity of metal uptake (atomic absorption and X-ray fluorescence), the type of staining response (electron scattering profile of thin-sections), and the crystallinity of the deposition product (X-ray diffraction of embedded specimens) determined.Since most biological material possesses little electron scattering ability electron microscopists have been forced to depend on heavy metal impregnation of the specimen before obtaining thin-section data. Our experience with these walls suggested that they may provide a suitable model system with which to study the sites of reaction for this metal deposition.

The Filter Loop Technique as a Method of Measuring Platelet Aggregation in the Flowing Blood of the Rat; the Inhibitory Activity of 5-oxo-l-cyclopentene-l-heptanoic Acid (AY-16,804) on Platelet Aggregation

1973 ◽  
Vol 30 (01) ◽  
pp. 138-147 ◽  
Author(s):  
Christopher R. Muirhead
Keyword(s):  
Platelet Aggregation ◽  
Prostaglandin E1 ◽  
Suitable Model ◽  
Heptanoic Acid ◽  
Simple Method ◽  
Loop Technique ◽  
Flowing Blood ◽  
Filter Loop

SummaryThe filter loop technique which measures platelet aggregation in vivo in the flowing-blood of the rat was compared to the optical density technique of Born which is carried out in vitro with platelet rich plasma. Using these two experimental models the effect on platelet aggregation of three known inhibitors sulfinpyrazone, dipyridamole and prostaglandin E1, and a novel compound 5-oxo-l-cyclopentene-l-heptanoic acid (AY-16, 804) was determined.The effects on platelet aggregation of the known inhibitors were consistent with information in the literature. Prostaglandin E1 was the most potent inhibitor in both techniques; sulfinpyrazone inhibited aggregation in both models but was less potent than prostaglandin E1. AY-16, 804 exhibited activity in vitro and in vivo similar to that of sulfinpyrazone. Dipyridamole did not inhibit platelet aggregation in vivo and did not inhibit aggregation in vitro in concentrations at which it remained soluble.The filter loop technique is a suitable model for measuring platelet aggregation in the flowing blood of the rat. It is a relatively simple method of determining aggregation and easily adapted to other species.

ON SUITABLE MODEL SELECTION APPROACH FOR ANALYSIS OF MENTAL HEALTH SERVICE USE DATA

2019 ◽  
Vol 43 (2) ◽  
pp. 212-222
Author(s):  
DULAL K. BHAUMIK ◽  
◽  
SUBHASH ARYAL ◽  
SCOTT HUR ◽  
◽  
...  
Keyword(s):  
Mental Health ◽  
Mental Health Service ◽  
Model Selection ◽  
Health Service ◽  
Service Use ◽  
Mental Health Service Use ◽  
Health Service Use ◽  
Suitable Model ◽  
Model Selection Approach ◽  
Selection Approach

A SOFT SYSTEMS METHODOLOGY APPROACH TO IMPROVING THE SUPPLY CHAIN OF A CONSTRUCTION PROJECT IN GAUTENG PROVINCE, SOUTH AFRICA

2020 ◽  
Vol 10 (1) ◽  
pp. 86-99
Author(s):  
Lewis Tsuro ◽  
Stan Hardman
Keyword(s):  
South Africa ◽  
Supply Chain ◽  
Construction Project ◽  
Soft Systems Methodology ◽  
Project Planning ◽  
Suitable Model ◽  
Senior Managers ◽  
Good Tool ◽  
Systems Methodology ◽  
Soft Systems

The Soft Systems Methodology (SSM) was developed as a set of tools for identifying and making incremental steps to improve situations with poorly defined causes or solutions. The supply chain forms a key process of any construction project; however, on any given construction site, supply chain inefficiencies could arise from many different avenues. Opinions vary, though, on which of these avenues is more important for increasing supply chain efficiencies; whether any problem even exist across the different aspects of the supply chain; as well as what steps should be taken to resolve them. It was therefore studied, here, whether SSM could be employed as a useful tool to systematically apply in the supply chains of a construction project in South Africa, for understanding and targeting the problematic situations that arise. Following thorough cyclical open-ended interviews with 17 workers, supervisors, foremen, site clerks, senior managers, and the CEO of the principal contractor at a new office park construction project in Rosebank, Johannesburg, and a thematic analysis of the data, SSM was performed to understand the existing challenges, and develop a suitable model for improvement. The study found that SSM was a good tool for understanding the ‘messy’ circumstances surrounding the chosen construction project supply chain, as well as actions that could be taken to improve the supply chain’s efficiency on site. The findings add weight to the argument that SSM could be a good tool for project managers to systematically introduce into their project planning regimens

Propionic Acid Shapes the Course of Multiple Sclerosis by a Distinct Immunomodulatory and Neuroprotective Mechanism

2018 ◽  
Author(s):  
Alexander Duscha ◽  
Barbara Gisevius ◽  
Sarah Hirschberg ◽  
Stefanie Haase ◽  
Gabriele I. Stangl ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Propionic Acid

Analysis and design of suitable model structures for activated sludge tanks with circulating flow

1999 ◽  
Vol 39 (4) ◽  
pp. 55-60 ◽  
Author(s):  
J. Alex ◽  
R. Tschepetzki ◽  
U. Jumar ◽  
F. Obenaus ◽  
K.-H. Rosenwinkel
Keyword(s):  
Activated Sludge ◽  
Large Scale ◽  
Wastewater Treatment Plants ◽  
Treatment Plant ◽  
High Sensitivity ◽  
Suitable Model ◽  
Model Structure ◽  
Analysis And Design ◽  
Hydraulic Behaviour ◽  
Model Structures

Activated sludge models are widely used for planning and optimisation of wastewater treatment plants and on line applications are under development to support the operation of complex treatment plants. A proper model is crucial for all of these applications. The task of parameter calibration is focused in several papers and applications. An essential precondition for this task is an appropriately defined model structure, which is often given much less attention. Different model structures for a large scale treatment plant with circulation flow are discussed in this paper. A more systematic method to derive a suitable model structure is applied to this case. Results of a numerical hydraulic model are used for this purpose. The importance of these efforts are proven by a high sensitivity of the simulation results with respect to the selection of the model structure and the hydraulic conditions. Finally it is shown, that model calibration was possible only by adjusting to the hydraulic behaviour and without any changes of biological parameters.

Excess molar volumes of binary mixtures of acetic acid and propionic acid with some members of homologous series of alkanes

1991 ◽  
Vol 56 (4) ◽  
pp. 736-744 ◽  
Author(s):  
Ondřej Drábek ◽  
Ivan Cibulka
Keyword(s):  
Acetic Acid ◽  
Propionic Acid ◽  
Alkyl Chain ◽  
Excess Molar Volumes ◽  
Liquid Mixtures ◽  
Entire Concentration Range ◽  
Molar Volumes ◽  
Binary Liquid ◽  
Alkane Molecule ◽  
Increasing Temperature

Excess molar volumes of binary liquid mixtures of (acetic or propionic acid = hexane) at 25 and 35°C, and (acetic or propionic acid + heptane or octane) and (acetic acid + dodecane) at 25°C, measured with a tilting dilution dilatometer, are reported. The excess volumes are positive over the entire concentration range for all mixtures and increase with increasing length of an alkane molecule, decrease with increasing of the alkyl chain in a molecule of carboxylic acid, and increase with increasing temperature.

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