Maternal Exercise During Pregnancy

1994 ◽  
Vol 18 (4) ◽  
pp. 215-217 ◽  
Author(s):  
James M. Pivarnik
Keyword(s):  
Maternal Exercise ◽  
Exercise During Pregnancy

scholarly journals Exercise Intergenerationally Drives Muscle-Based Thermogenesis and Myogenesis in Offspring Impaired Due to Maternal Obesity

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1083-1083
Author(s):  
Jun Seok Son ◽  
Song Ah Chae ◽  
Mei-Jun Zhu ◽  
Min Du
Keyword(s):  
Gene Expression ◽  
Surface Temperature ◽  
Muscle Development ◽  
Maternal Obesity ◽  
Experimental Unit ◽  
Obesogenic Diet ◽  
Maternal Exercise ◽  
The Impact ◽  
Exercise During Pregnancy ◽  
Fetal Muscle

Abstract Objectives Maternal obesity (MO) predisposes metabolic dysfunction in offspring muscle. Skeletal muscle-dependent non-shivering thermogenesis (NST) is emerging as a critical mechanism for maintaining energy homeostasis, but the effects of maternal exercise on muscle-based thermogenesis in offspring remains unexplored. In addition, the impact of maternal obesity and exercise on fetal muscle development is unclear, which will also be examined. The objective of the current study is to explore the effects of maternal exercise on muscle-based thermogenesis and myogenesis in fetuses impaired due to MO. Methods Female C57BL/6 J mice were randomized and assigned to either control (CON, 10 kcal% from fat) or obesogenic diet (OB, 60 kcal% from fat) for 8 weeks to induce obesity and then mated. Then, pregnant mice in obesogenic diet were further separated into two groups with/without exercise (daily 60 min exercise) during pregnancy, which resulted in three treatments: control (CON), OB, and OB-EX (n = 6 per group). Fetal skeletal muscles were collected at embryonic day 18.5 (E18.5). In another cohort of animals, maternal mice were allowed to give birth and surface temperature of neonates was measured. Statistical analysis were conducted using one way analysis of variance (ANOVA); a pregnancy/litter was considered as an experimental unit. Results OB reduced surface temperature of neonates (P < 0.01). In E18.5 fetal muscle, OB downregulated muscle-based thermogenic gene expression (P < 0.05), including Sln, Serca2, and Ryr1. In addition, the expression of mitochondriogenic genes (P < 0.05), including Ppargc1a and Tfam, was also reduced in OB fetal female and male muscle. These adverse changes were prevented due to exercise during pregnancy. Furthermore, maternal exercise protected against the downregulation of myogenesis-related gene expression, including MyoD, Myogenin, Myf5, and Pax7, due to MO. Conclusions Exercise during pregnancy enhanced muscle-based thermogenic gene expression and myogenesis which were impaired due to MO, suggesting that maternal exercise intergenerationally improves metabolic health of offspring. Funding Sources Supported by NIH Grant R01HD067449.

scholarly journals Maternal Aerobic Exercise during Pregnancy Can Increase Spatial Learning by Affecting Leptin Expression on Offspring's Early and Late Period in Life Depending on Gender

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Ayfer Dayi ◽  
Sinem Agilkaya ◽  
Seda Ozbal ◽  
Ferihan Cetin ◽  
Ilkay Aksu ◽  
...  
Keyword(s):  
Aerobic Exercise ◽  
Spatial Learning ◽  
Leptin Receptor ◽  
Hippocampal Neurogenesis ◽  
Receptor Expression ◽  
Control Group ◽  
Male Adult ◽  
Brain Functions ◽  
Maternal Exercise ◽  
Exercise During Pregnancy

Maternal exercise during pregnancy has been suggested to exert beneficial effects on brain functions of the offspring. Leptin is an adipocytokine which is secreted from adipose tissues and has positive effects on learning, memory, and synaptic plasticity. In this study, pregnant rats were moderately exercised and we observed the effects of this aerobic exercise on their prepubertal and adult offsprings' spatial learning, hippocampal neurogenesis, and expression of leptin. All the pups whose mothers exercised during pregnancy learned the platform earlier and spent longer time in the target quadrant. Their thigmotaxis times were shorter than those measured in the control group. It is shown that hippocampal CA1, CA3 neuron numbers increased in both prepubertal and adult pups, in addition that GD neuron numbers increased in adult pups. Leptin receptor expression significantly increased in the prepubertal male, adult male, and adult female pups. In our study, maternal running during pregnancy resulted in significant increase in the expression of leptin receptor but not in prepubertal female pups, enhanced hippocampal cell survival, and improved learning memory capability in prepubertal and adult rat pups, as compared to the control group. In conclusion, maternal exercise during pregnancy may regulate spatial plasticity in the hippocampus of the offspring by increasing the expression of leptin.

Fetal Heart Rate Variability Following An Acute Bout Of Maternal Exercise During Pregnancy

2016 ◽  
Vol 48 ◽  
pp. 204
Author(s):  
Joseph P. Abaji ◽  
Robert Davis Moore ◽  
Élise Labonté-Lemoyne ◽  
Daniel Curnier ◽  
Dave Ellemberg
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Acute Bout ◽  
Fetal Heart Rate Variability ◽  
Maternal Exercise ◽  
Exercise During Pregnancy

Maternal exercise during pregnancy affects mitochondrial enzymatic activity and biogenesis in offspring brain

2013 ◽  
Vol 123 (4) ◽  
pp. 253-264 ◽  
Author(s):  
Jong-won Park ◽  
Mun-Hee Kim ◽  
Su-Ju Eo ◽  
Eun-Ho Lee ◽  
Jong-Suk Kang ◽  
...  
Keyword(s):  
Enzymatic Activity ◽  
Maternal Exercise ◽  
Exercise During Pregnancy

Impact of Maternal Exercise during Pregnancy on Arterial Function and Atherosclerosis Formation in Swine Offspring Fed a High Fat Diet

2015 ◽  
Vol 02 (01) ◽  
Author(s):  
Nicole Blaize ◽  
Erica Zartman ◽  
Thomas Biel ◽  
Craig Goergen ◽  
William Van Alstine ◽  
...  
Keyword(s):  
High Fat Diet ◽  
High Fat ◽  
Arterial Function ◽  
Maternal Exercise ◽  
Exercise During Pregnancy

scholarly journals Maternal exercise during pregnancy reduces risk of mammary tumorigenesis in rat offspring

2014 ◽  
Vol 23 (6) ◽  
pp. 502-505 ◽  
Author(s):  
Ignacio G. Camarillo ◽  
Leon Clah ◽  
Wei Zheng ◽  
Xuanzhu Zhou ◽  
Brienna Larrick ◽  
...  
Keyword(s):  
Mammary Tumorigenesis ◽  
Rat Offspring ◽  
Maternal Exercise ◽  
Exercise During Pregnancy

Maternal and fetal responses to exercise during pregnancy

1985 ◽  
Vol 65 (1) ◽  
pp. 1-36 ◽  
Author(s):  
F. K. Lotgering ◽  
R. D. Gilbert ◽  
L. D. Longo
Keyword(s):  
Acute Exercise ◽  
Sedentary Lifestyle ◽  
Late Pregnancy ◽  
Important Variable ◽  
External Work ◽  
Blood Concentrations ◽  
Cardiovascular Hemodynamics ◽  
Physiological Alterations ◽  
Maternal Exercise ◽  
Exercise During Pregnancy

Exercise has numerous effects on the pregnant woman, the developing fetus, and the placenta. In turn, pregnancy affects the ability to perform physical activity. During pregnancy, increased metabolism at rest results almost exclusively from the gestational increase in mass. Because of this increase, a higher cardiorespiratory effort is required to perform a given amount of external work. One would expect the result to be some training effect, unless a more sedentary lifestyle is adopted. The possibility that maximal O2 consumption may increase during pregnancy has not been studied extensively, yet it is a most important variable that puts other changes in perspective. The sedentary lifestyle commonly adopted in late pregnancy in most western societies may reflect a cultural rather than a physiological phenomenon. In contrast to the physiological alterations in the mother and despite the reductions in uterine blood flow during maternal exercise, physiological changes in the fetus are small. Relatively minor changes occur in the blood concentrations of O2 and substrates during prolonged exhaustive exercise. In addition, despite a temperature increase of 1 to 2 degrees C, there is little evidence for significant alteration in fetal metabolism, cardiovascular hemodynamics, or blood catecholamine concentrations. These observations suggest that acute exercise normally does not represent a major stress for the fetus. Of course, most of the information concerning the fetus is derived from studies in experimental animals, particularly in sheep. In humans the upright position and increased uterine contractibility may affect the fetal responses differently. Virtually nothing is known about the physiological effects of exercise training on the fetus. The most likely effect may be a relatively small reduction in birth weight in some species, but this needs further investigation. Further studies are also needed for a more complete understanding of the mechanisms involved in the remarkably effective mechanisms that account for the relative homeostasis of the fetus during maternal exercise.

scholarly journals Maternal exercise during pregnancy promotes physical activity in adult offspring

2016 ◽  
Vol 30 (7) ◽  
pp. 2541-2548 ◽  
Author(s):  
Jesse D. Eclarinal ◽  
Shaoyu Zhu ◽  
Maria S. Baker ◽  
Danthasinghe B. Piyarathna ◽  
Cristian Coarfa ◽  
...  
Keyword(s):  
Physical Activity ◽  
Adult Offspring ◽  
Maternal Exercise ◽  
Exercise During Pregnancy
Sign in / Sign up

Export Citation Format

Share Document