scholarly journals Implication of Clinical Pathway Care for Community-Acquired Pneumonia in a Community Hospital: Early Switch from an Intravenous β-lactam Plus a Macrolide to an Oral Respiratory Fluoroquinolone

2008 ◽  
Vol 47 (21) ◽  
pp. 1865-1874 ◽  
Author(s):  
Yuichiro Shindo ◽  
Shinji Sato ◽  
Eiichi Maruyama ◽  
Takamasa Ohashi ◽  
Masahiro Ogawa ◽  
...  
2020 ◽  
pp. 089719002095303
Author(s):  
Jessica Yu ◽  
Gillian Wang ◽  
Ann Davidson ◽  
Ivy Chow ◽  
Ada Chiu

Background: A local health authority in Canada implemented its own Antimicrobial Stewardship Program (ASP) which provide guidelines to clinicians to utilize when treating infectious diseases such as community-acquired pneumonia (CAP). Objectives: The primary objective is to describe antibiotic usage patterns at the community hospital’s emergency department (ED) and to analyze the patterns in relation to ASP goals of reducing risk of infections, adverse drug events and antibiotic resistance, and to identify potential areas of improvement. Methods: This retrospective chart review included 156 adult patients with a diagnosis of CAP admitted to a community hospital ED from December 1, 2015 to November 30, 2016. Results: 50.6% patients were prescribed moxifloxacin across all severity of CAP patients. Low and moderate severity CAP patients were most often prescribed antibiotic duration > 7 days. In low, moderate and high severity CAP patients who were treated using ceftriaxone, 100%, 88.9% and 66.6% patients were treated with ceftriaxone 2000 mg daily respectively. Conclusions: Antibiotic prescribing patterns suggest fluoroquinolones were frequently being over-prescribed, ceftriaxone dosages were often too high, and duration of antibiotics for low and moderate severity CAP were too long. More efforts are needed to promote appropriate antibiotic usage and optimize patient care.


CHEST Journal ◽  
2014 ◽  
Vol 146 (4) ◽  
pp. 927A
Author(s):  
Bikash Bhattarai ◽  
Meenakshi Ghosh ◽  
Abhisekh Sinha Ray ◽  
Saurav Dwivedi ◽  
Chawmay Aye ◽  
...  

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0193581 ◽  
Author(s):  
Daniele Donà ◽  
Silvia Zingarella ◽  
Andrea Gastaldi ◽  
Rebecca Lundin ◽  
Giorgio Perilongo ◽  
...  

2013 ◽  
Vol 125 (21-22) ◽  
pp. 674-679 ◽  
Author(s):  
Herbert Kurz ◽  
Hubert Göpfrich ◽  
Klaus Huber ◽  
Walter Krugluger ◽  
Friederike Asbott ◽  
...  

2021 ◽  
pp. 089719002110397
Author(s):  
Elizabeth W. Covington ◽  
Alanna Rufe

Background: The 2019 Infectious Disease Society of America (IDSA) guidelines for the management of community-acquired bacterial pneumonia encourage the identification of locally validated risk factors for methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa to guide empiric therapy decisions for patients with community-acquired pneumonia (CAP). The guidelines urge clinicians to perform local validation to determine prevalence and risk factors pertinent to their institution. Objective: To determine the percentage of community-acquired pneumonia caused by multidrug-resistant organisms (MDROs) and assess risk factors potentially associated with multidrug-resistant organisms CAP at our hospital. Methods: This was a retrospective case control study analyzing patients admitted to the 344-bed community hospital with bacterial community-acquired pneumonia between January 1, 2019 and December 31, 2019. Univariate analysis and multivariate regression were performed to assess potential risk factors for MDRO pathogens. Results: MDROs were isolated in 41.3% of patients with culture-positive CAP (n=19/46), and 3.6% of patients with microbiological culture data within 48 hours of admission (19/527). Among patients with culture-positive CAP, hospitalization in the previous 90 days and receipt of antibiotics in the previous 90 days occurred more frequently in MDRO patients than non-MDRO patients (37% vs 11%, P=.032). No risk factors reached statistical significance in the multivariate regression. There were no differences in clinical outcomes between MDRO and non-MDRO patients. Conclusions: This study demonstrated a low overall prevalence of MDRO pathogens in patients with CAP. Potential risk factors for MDRO included hospitalization within the past 90 days and antibiotic use within the past 90 days.


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