Cancer Imaging, Therapy and Theranostics Based on Different Types of Functional Materials

2018 ◽  
Vol 25 (25) ◽  
pp. 2874-2875 ◽  
Author(s):  
Aiguo Wu
2019 ◽  
Vol 19 (4) ◽  
pp. 312-323
Author(s):  
Agnieszka Brochocka ◽  
Aleksandra Zagawa ◽  
Rafał Panek ◽  
Jarosław Madej ◽  
Wojciech Franus

Abstract In this work, a method for introducing zeolites and mesoporous siliceous materials into the melt-blown process for the production of polypropylene nonwovens was developed and the functional materials obtained were tested. Both types of additives were introduced in the melt-blown technology using a device placed in the duct of the die assembly. Nine types of polypropylene melt-blown nonwovens were made with different types of zeolites (clinoptilolite, Na-X, Na-A, Na-P1, sodalite, Na-P1 with hexadecyl trimethylammonium bromide (HDTMA), ZeoEco 20, and BioZeo R.01) or mesoporous silica material (Mobil Composition of Matter No. 41, abbreviated as MCM-41). The nonwovens were studied in terms of protective and functional parameters: sodium chloride and paraffin oil mist aerosol penetration, airflow resistance, and sorption capacity for toluene, ammonia, acetone, and cyclohexane, in accordance with the requirements of the European standards concerning respiratory protective equipment. The tests showed that zeolites and MCM-41 can be successfully incorporated within the structure of elementary polymer fibers using an environmentally friendly “dry” melt-blown technology with nonwovens modified so as to impart multiple functionalities in one integrated technological process. The developed method of introducing the studied materials to polypropylene melt-blown nonwovens led to the production of new multipurpose materials with good protective and functional properties. The best polypropylene nonwovens were produced with the addition of 250 g/m2 of MCM-41 or Na-P1 zeolite modified with HDTMA.


2020 ◽  
Vol 8 (5) ◽  
pp. 1494-1516 ◽  
Author(s):  
Hongying He ◽  
Xin Lu ◽  
Emil Hanc ◽  
Chao Chen ◽  
Hao Zhang ◽  
...  

Pyroelectric materials are important functional materials that can generate an electrical response upon a temperature change. In recent years, significant advances have been achieved in different types of lead-free pyroelectrics and are rising to potential energy-related applications.


2020 ◽  
Vol 02 (01) ◽  
pp. 047-063 ◽  
Author(s):  
Nelson Ricardo Ávila-Rovelo ◽  
Amparo Ruiz-Carretero

Supramolecular approaches are of great interest in the design of functional materials. The types of aggregates arising from different noncovalent interactions endow materials with intriguing properties. In this sense, J-type aggregates are very attractive due to their unique optical properties and capacity to transport excitons. These features make them great candidates in the design of materials for organic electronic devices. Furthermore, the incorporation of additional hydrogen-bonding functionalities provides J-aggregates with superior directionality and connection among the different π-conjugated cores. The control over the formation of H-bonds to achieve functional aggregates is therefore a promising strategy towards controlled structures with specific functions.This review outlines the most relevant and recent works of π-conjugated systems exhibiting J-type aggregates resulting from hydrogen-bonding interactions. Different types of hydrogen-bonding functionalities will be discussed together with their roles in the aggregate properties, their impact in the optoelectronic properties, the self-assembly mechanisms, and their applications in organic electronics.


2017 ◽  
Vol 5 (5) ◽  
pp. 901-952 ◽  
Author(s):  
Shine Augustine ◽  
Jay Singh ◽  
Manish Srivastava ◽  
Monica Sharma ◽  
Asmita Das ◽  
...  

This review deals with four different types of carbon allotrope based nanosystems and summarizes the results of recent studies that are likely to have applications in cancer theranostics. We discuss the applications of these nanosystems for cancer imaging, drug delivery, hyperthermia, and PDT/TA/PA.


Pharmaceutics ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 280 ◽  
Author(s):  
Ki-Taek Kim ◽  
Jae-Young Lee ◽  
Dae-Duk Kim ◽  
In-Soo Yoon ◽  
Hyun-Jong Cho

Diverse nanosystems for use in cancer imaging and therapy have been designed and their clinical applications have been assessed. Among a variety of materials available to fabricate nanosystems, poly(lactic-co-glycolic acid) (PLGA) has been widely used due to its biocompatibility and biodegradability. In order to provide tumor-targeting and diagnostic properties, PLGA or PLGA nanoparticles (NPs) can be modified with other functional materials. Hydrophobic or hydrophilic therapeutic cargos can be placed in the internal space or adsorbed onto the surface of PLGA NPs. Protocols for the fabrication of PLGA-based NPs for cancer imaging and therapy are already well established. Moreover, the biocompatibility and biodegradability of PLGA may elevate its feasibility for clinical application in injection formulations. Size-controlled NP’s properties and ligand–receptor interactions may provide passive and active tumor-targeting abilities, respectively, after intravenous administration. Additionally, the introduction of several imaging modalities to PLGA-based NPs can enable drug delivery guided by in vivo imaging. Versatile platform technology of PLGA-based NPs can be applied to the delivery of small chemicals, peptides, proteins, and nucleic acids for use in cancer therapy. This review describes recent findings and insights into the development of tumor-targeted PLGA-based NPs for use of cancer imaging and therapy.


Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 693
Author(s):  
Paolo Dognini ◽  
Christopher R. Coxon ◽  
Wendel A. Alves ◽  
Francesca Giuntini

The covalent and noncovalent association of self-assembling peptides and tetrapyrroles was explored as a way to generate systems that mimic Nature’s functional supramolecular structures. Different types of peptides spontaneously assemble with porphyrins, phthalocyanines, or corroles to give long-range ordered architectures, whose structure is determined by the features of both components. The regular morphology and ordered molecular arrangement of these systems enhance the photochemical properties of embedded chromophores, allowing applications as photo-catalysts, antennas for dye-sensitized solar cells, biosensors, and agents for light-triggered therapies. Chemical modifications of peptide and tetrapyrrole structures and control over the assembly process can steer the organization and influence the properties of the resulting system. Here we provide a review of the field, focusing on the assemblies obtained from different classes of self-assembling peptides with tetrapyrroles, their morphologies and their applications as innovative functional materials.


Coatings ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1000
Author(s):  
Eduardo Guzmán

Fluid interfaces are promising candidates for the design of new functional materials by confining different types of materials, e.g., polymers, surfactants, colloids, or even small molecules, by direct spreading or self-assembly from solutions. The development of such materials requires a deep understanding of the physico-chemical bases underlying the formation of layers at fluid interfaces, as well as the characterization of the structures and properties of such layers. This is of particular importance, because the constraints associated with the assembly of materials at the interface lead to the emergence of equilibrium and dynamic features in the interfacial systems that are far from those found in traditional 3D materials. These new properties are of importance in many scientific and technological fields, such as food science, cosmetics, biology, oil recovery, electronics, drug delivery, detergency, and tissue engineering. Therefore, the understanding of the theoretical and practical aspects involved in the preparation of these interfacial systems is of paramount importance for improving their usage for designing innovative technological solutions.


2011 ◽  
Vol 356-360 ◽  
pp. 349-354 ◽  
Author(s):  
Xing Xing Gu ◽  
Ya Han ◽  
Jin Jin Chen ◽  
Jian Rong Chen

Due to their large surface areas, high pore volumes, relatively even distributions of pore sizes, surfaces enriched with unsaturated groups and orderly long-range structures, the mesoporous materials have been widely applied in industries such as chemical, biomedical, environmental protection and functional materials. In recent years, many scientists have demonstrated that the mesoporous molecular sieves have better adsorption of dyes in wastewater. This paper reviews the applications of different types of mesoporous adsorbents for removal of dyes in wastewater. It also presents the challenges and prospects in using the mesoporous materials for dye removal in wastewater treatment.


2019 ◽  
Vol 7 (34) ◽  
pp. 19634-19650 ◽  
Author(s):  
Anne-Marie Caminade ◽  
Abdellah Beraa ◽  
Régis Laurent ◽  
Béatrice Delavaux-Nicot ◽  
Mohamed Hajjaji

The interaction of dendrimers or hyper-branched polymers with clays produces different types of new materials.


2021 ◽  
Vol 9 ◽  
Author(s):  
Sujeung Lim ◽  
Yuyao Kuang ◽  
Herdeline Ann M. Ardoña

Supramolecular materials, which rely on dynamic non-covalent interactions, present a promising approach to advance the capabilities of currently available biosensors. The weak interactions between supramolecular monomers allow for adaptivity and responsiveness of supramolecular or self-assembling systems to external stimuli. In many cases, these characteristics improve the performance of recognition units, reporters, or signal transducers of biosensors. The facile methods for preparing supramolecular materials also allow for straightforward ways to combine them with other functional materials and create multicomponent sensors. To date, biosensors with supramolecular components are capable of not only detecting target analytes based on known ligand affinity or specific host-guest interactions, but can also be used for more complex structural detection such as chiral sensing. In this Review, we discuss the advancements in the area of biosensors, with a particular highlight on the designs of supramolecular materials employed in analytical applications over the years. We will first describe how different types of supramolecular components are currently used as recognition or reporter units for biosensors. The working mechanisms of detection and signal transduction by supramolecular systems will be presented, as well as the important hierarchical characteristics from the monomers to assemblies that contribute to selectivity and sensitivity. We will then examine how supramolecular materials are currently integrated in different types of biosensing platforms. Emerging trends and perspectives will be outlined, specifically for exploring new design and platforms that may bring supramolecular sensors a step closer towards practical use for multiplexed or differential sensing, higher throughput operations, real-time monitoring, reporting of biological function, as well as for environmental studies.


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