The Role of Vitamin D in Dyslipidemia and Cardiovascular Disease

2011 ◽  
Vol 17 (9) ◽  
pp. 933-942 ◽  
Author(s):  
Armin Zittermann ◽  
Jan F. Gummert ◽  
Jochen Borgermann
Heart ◽  
2012 ◽  
Vol 98 (8) ◽  
pp. 609-614 ◽  
Author(s):  
Ian R Reid ◽  
Mark J Bolland

2008 ◽  
Vol 5 (2) ◽  
pp. 45-54
Author(s):  
M A Berkovskaya

The role of interleukin-6 in insulin resistance, body fat distribution and energy balance Disorders of glucose metabolism and risk of oral cancer. Duration of lactation is associated with lower prevalence of the metabolic syndrome in midlife--SWAN, the study of women's health across the nation. Vitamin D deficiency and risk of cardiovascular disease. Adypocyte prolactin: regulation of release and putative functions.


2012 ◽  
Vol 225 (2) ◽  
pp. 253-263 ◽  
Author(s):  
Vincent M. Brandenburg ◽  
Marc G. Vervloet ◽  
Nikolaus Marx

2018 ◽  
Vol 07 (02) ◽  
Author(s):  
Moretti HD ◽  
Grant WB ◽  
Berry BD ◽  
Colucci VJ

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Sebastian T. Lugg ◽  
Phillip A. Howells ◽  
David R. Thickett

First described in relation to musculoskeletal disease, there is accumulating data to suggest that vitamin D may play an important role in cardiovascular disease (CVD). In this review we aim to provide an overview of the role of vitamin D status as both a marker of and potentially causative agent of hypertension, coronary artery disease, heart failure, atrial fibrillation, stroke, and peripheral vascular disease. The role of vitamin D levels as a disease marker for all-cause mortality is also discussed. We review the current knowledge gathered from experimental studies, observational studies, randomised controlled trials, and subsequent systematic reviews in order to suggest the optimal vitamin D level for CVD protection.


2013 ◽  
Vol 87 (12) ◽  
pp. 2083-2103 ◽  
Author(s):  
Stefan Pilz ◽  
Martin Gaksch ◽  
Bríain O’Hartaigh ◽  
Andreas Tomaschitz ◽  
Winfried März

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Lisa Wenyang Fu ◽  
Ronald Vender

The novel discovery of the systemic role of vitamin D in the modulation of the immune system especially the Type 1 helper T cell (Th1) pathway reveals its potential for treating Th1 inflammatory diseases. Psoriasis has been recently established to be a systemic disease centered on inflammation and involvement of cytokines of the Th1 pathway. There is an increased prevalence of metabolic syndrome in patients with psoriasis. Metabolic syndrome also involves a proinflammatory state. This paper proposes the idea of the potential use of oral vitamin D to treat psoriasis and metabolic syndrome concurrently. We propose there is merit in more clinical trials investigating the use of vitamin D to treat both psoriasis and metabolic syndrome through its anti-inflammatory effects. On application to psoriasis management and prognosis, the goal is to decrease the risk for cardiovascular disease and decrease disease morbidity and mortality.


2014 ◽  
Vol 17 (3) ◽  
pp. 27-30 ◽  
Author(s):  
L V Egshatyan ◽  
E N Dudinskaya ◽  
O N Tkacheva ◽  
D A Kashtanova

This review shows the role of vitamin D in the regulation of not only the level of calcium, but also in the pathogenesis of chronic systemic inflammation, disruption of insulin sensitivity of tissues. The sufficient levels of vitamin D in the blood can lead to reduced risk of developing type 2 diabetes, obesity, autoimmune destruction of pancreatic β-cells, certain cardiometa-bolic risk factors, and therefore cardiovascular disease. Perhaps preparations of vitamin D in the near future may become additional and necessary nutritional substances for correction of insulin resistance, cardiovascular disease, chronic inflammation and prevention of disorders of glucose metabolism.


2015 ◽  
Vol 9 (1) ◽  
pp. 40-49 ◽  
Author(s):  
Natália Ribeiro Mandarino ◽  
Francisco das Chagas Monteiro Júnior ◽  
João Victor Leal Salgado ◽  
Joyce Santos Lages ◽  
Natalino Salgado Filho

The role of vitamin D in the regulation of bone metabolism has been well established. However, in recent years, many studies have demonstrated that its role extends far beyond bone health. Growing evidence has shown a strong association between vitamin D deficiency and hypertension, metabolic syndrome, diabetes mellitus and atherosclerosis. The mechanisms by which vitamin D exerts its cardiovascular protective effects are still not completely understood, but there is evidence that it participates in the regulation of renin-angiotensin system and the mechanisms of insulin sensitivity and activity of inflammatory cytokines, besides its direct cardiovascular actions. In this review, several studies linking vitamin D deficiency with cardiometabolic risk as well as small randomized trials that have evaluated the cardiovascular effects of its supplementation are presented. However, large randomized placebo-controlled studies are still needed before we can definitively establish the role of vitamin D supplementation in the prevention and control of cardiovascular disease.


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