Pharmaceutical and Biomedical Applications of Green Synthesized Metal and Metal Oxide Nanoparticles

2020 ◽  
Vol 26 (45) ◽  
pp. 5844-5865
Author(s):  
Nabila Zafar ◽  
Ahmed Madni ◽  
Ayesha Khalid ◽  
Taous Khan ◽  
Rozina Kousar ◽  
...  
Keyword(s):  
Side Effects ◽  
Metal Oxide ◽  
Metal Oxides ◽  
Biomedical Applications ◽  
Metal Oxide Nanoparticles ◽  
Biological Properties ◽  
Oxide Nanoparticles ◽  
Green Protocol ◽  
Biological Sources ◽  
Synthesis Of Nanomaterials

Background: Due to the rapid growth in life threatening diseases such as cancer, diabetes, chronic wound and HIV/AIDS along with rise of side effects of the current treatments, world is now focusing to utilize new treatment options. Currently, the development of green nanotechnology field seems as a potential alternate for diseases diagnosis and treatment by preparation of various sizes and shapes of nanomaterials. Objective: This review is to present the explored biological sources in synthesis of nanomaterials particularly metal and metal oxides nanoparticles and critical review of the applications of biosynthesized nanoparticles in pharmaceutical and biomedical fields. Methods: In this review, the various biological sources including bacteria, fungi, algae and plants used in synthesis of nanomaterials and mechanism involved in preparation are elaborated. In addition, biosynthesized nanomaterials applied as drug delivery system for anticancer, antibiotic, antidiabetic agent and functioned as potential diagnostic, antimicrobial, anticancer and wound healing candidates are comprehensively reviewed. Results: The synthesized metal and metal oxides from green protocol proved to have advantages such as being biocompatible, effective and cheap. Furthermore, the green synthesized metal and metal oxide nanoparticles showed to possess prominent physical, chemical and biological properties that can be efficiently utilized for pharmaceutical and biomedical applications. Conclusion: The information gathered in this review will provide a baseline for exploring more potential usage of green synthesized metal and metal oxide nanomaterials for various other applications. However, a concrete understanding of the safety of these nanomaterials is still needed to minimize the potential side effects.

Surface coating and functionalization of metal and metal oxide nanoparticles for biomedical applications

2022 ◽  
pp. 205-231
Author(s):  
Raj Kumar ◽  
Guruprasad Reddy Pulikanti ◽  
Konathala Ravi Shankar ◽  
Darsi Rambabu ◽  
Venkateswarulu Mangili ◽  
...  
Keyword(s):  
Metal Oxide ◽  
Surface Coating ◽  
Biomedical Applications ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles

A Review on Antimicrobial Properties of Metal Nanoparticles

2020 ◽  
Vol 20 (6) ◽  
pp. 3303-3339 ◽  
Author(s):  
Saee Gharpure ◽  
Aman Akash ◽  
Balaprasad Ankamwar
Keyword(s):  
Titanium Dioxide ◽  
Metal Oxide ◽  
Biomedical Applications ◽  
Antimicrobial Agents ◽  
Metal Oxide Nanoparticles ◽  
Antimicrobial Properties ◽  
Multidrug Resistant ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Micro Organisms

The field of nanotechnology elaborates the synthesis, characterization as well as application of nanomaterials. Applications of nanoparticles in various fields have interested scientists since decades due to its unique properties. Combination of pharmacology with nanotechnology has helped in development of newer antimicrobial agents in order to control the ever increasing multidrug resistant micro-organisms. Properties of metal and metal oxide nanoparticles like silver, gold, titanium dioxide as well as magnesium oxide as antimicrobial agents are very well known. This review elaborates synthesis methods and antimicrobial mechanisms of various metal as well as metal oxide nanoparticles for better understanding in order to utilize their potentials in various biomedical applications.

scholarly journals Biocompatible Metal-Oxide Nanoparticles: Nanotechnology Improvement of Conventional Prosthetic Acrylic Resins

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Laura S. Acosta-Torres ◽  
Luz M. López-Marín ◽  
R. Elvira Núñez-Anita ◽  
Genoveva Hernández-Padrón ◽  
Victor M. Castaño
Keyword(s):  
Metal Oxide ◽  
Metal Oxides ◽  
Metal Nanoparticles ◽  
Suspension Polymerization ◽  
Metal Oxide Nanoparticles ◽  
Physicochemical Characterization ◽  
Dental Restoration ◽  
Oxide Nanoparticles ◽  
Dental Resins ◽  
Acrylic Resins

Nowadays, most products for dental restoration are produced from acrylic resins based on heat-cured Poly(Methyl MethAcrylate) (PMMA). The addition of metal nanoparticles to organic materials is known to increase the surface hydrophobicity and to reduce adherence to biomolecules. This paper describes the use of nanostructured materials, TiO2and Fe2O3, for simultaneously coloring and/or improving the antimicrobial properties of PMMA resins. Nanoparticles of metal oxides were included during suspension polymerization to produce hybrid metal oxides-alginate-containing PMMA. Metal oxide nanoparticles were characterized by dynamic light scattering, and X-ray diffraction. Physicochemical characterization of synthesized resins was assessed by a combination of spectroscopy, scanning electron microscopy, viscometry, porosity, and mechanical tests. Adherence ofCandida albicanscells and cellular compatibility assays were performed to explore biocompatibility and microbial adhesion of standard and novel materials. Our results show that introduction of biocompatible metal nanoparticles is a suitable means for the improvement of conventional acrylic dental resins.

Metal Oxide Nanoparticles: Potential Uses in Biomedical Applications

2014 ◽  
Vol 11 (2) ◽  
pp. 139-149 ◽  
Author(s):  
Denisa Ficai ◽  
Ovidiu Oprea ◽  
Anton Ficai ◽  
Alina Holban
Keyword(s):  
Metal Oxide ◽  
Biomedical Applications ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles

Green Route for the Fabrication of ZnO Nanoparticles and Potential Functionalization with Chitosan Using Cross-linkers: A Review

2021 ◽  
Vol 3 (1) ◽  
pp. 1-25
Author(s):  
Hemra Hamrayev ◽  
Kamyar Shameli ◽  
Mostafa Yusefi ◽  
Serdar Korpayev
Keyword(s):  
Zinc Oxide ◽  
Metal Oxide ◽  
Green Synthesis ◽  
Zno Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Zno Nps ◽  
Biological Sources ◽  
Physical And Chemical

Zinc oxide is of significant importance for many industries due to its versatile properties, which have been enhanced with the production of this material in the nanoscale. Recent interest in the preparation of metal oxide nanoparticles using biological approaches has been reported in the literature. This technique known as “green synthesis” is an environmentally benign process than conventional methods like physical and chemical synthesis methods. Zinc oxide nanoparticles (ZnO-NPs) have been successfully obtained by green synthesis using different biological substrates like chitosan. Chitosan is biocompatible, biodegradable polymer having exclusive physical and chemical properties. Chitosan/metal oxide nanocomposite is a promising nanomaterial with enhanced properties for multiple functionalities. Therefore, this review discusses favorable approach in the formation of cross-linked Chitosan/ZnO nanocomposites attracting significant attention in various fields such biomedical due to their unique biodegradable, biocompatible, non-toxic nature. The use of biological sources, fabrication of green synthesized ZnO nanoparticles and its applications is briefly discussed. Overall, this review is a comprehensive study for the synthesis of ZnO-NPs using biological sources counting on their features and applications.

Adsorption of antifouling booster biocides on metal oxide nanoparticles: Effect of different metal oxides and solvents

2009 ◽  
Vol 64 (1) ◽  
pp. 20-26 ◽  
Author(s):  
Liubov Shtykova ◽  
Camilla Fant ◽  
Paul Handa ◽  
Ann Larsson ◽  
Kent Berntsson ◽  
...  
Keyword(s):  
Metal Oxide ◽  
Metal Oxides ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles

scholarly journals Encapsulation of ultrafine metal-oxide nanoparticles within mesopores for biomass-derived catalytic applications

2018 ◽  
Vol 9 (7) ◽  
pp. 1854-1859 ◽  
Author(s):  
Ruiqi Fang ◽  
Panliang Tian ◽  
Xianfeng Yang ◽  
Rafael Luque ◽  
Yingwei Li
Keyword(s):  
Metal Oxide ◽  
Metal Oxides ◽  
Noble Metal ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Ultrafine Metal ◽  
Noble Metal Oxides ◽  
Catalytic Applications

A versatile strategy using MOFs as precursors to encapsulate ultrasmall non-noble metal-oxides nanoparticles in the mesopores of KIT-6 is developed.

A unique space confined strategy to construct defective metal oxides within porous nanofibers for electrocatalysis

2020 ◽  
Vol 13 (12) ◽  
pp. 5097-5103
Author(s):  
Qi Hu ◽  
Ziyu Wang ◽  
Xiaowan Huang ◽  
Yongjie Qin ◽  
Hengpan Yang ◽  
...  
Keyword(s):  
Metal Oxide ◽  
Metal Oxides ◽  
Water Splitting ◽  
Organic Compounds ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Overall Water Splitting ◽  
Metal Organic ◽  
Facile Route

A facile route is developed for the synthesis of defective metal oxide nanoparticles within porous nanofibers by capitalizing on the distinct pyrolysis behaviors of metal–organic compounds and polymers for efficient overall water splitting.

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