A Review on Antimicrobial Properties of Metal Nanoparticles

2020 ◽  
Vol 20 (6) ◽  
pp. 3303-3339 ◽  
Author(s):  
Saee Gharpure ◽  
Aman Akash ◽  
Balaprasad Ankamwar
Keyword(s):  
Titanium Dioxide ◽  
Metal Oxide ◽  
Biomedical Applications ◽  
Antimicrobial Agents ◽  
Metal Oxide Nanoparticles ◽  
Antimicrobial Properties ◽  
Multidrug Resistant ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Micro Organisms

The field of nanotechnology elaborates the synthesis, characterization as well as application of nanomaterials. Applications of nanoparticles in various fields have interested scientists since decades due to its unique properties. Combination of pharmacology with nanotechnology has helped in development of newer antimicrobial agents in order to control the ever increasing multidrug resistant micro-organisms. Properties of metal and metal oxide nanoparticles like silver, gold, titanium dioxide as well as magnesium oxide as antimicrobial agents are very well known. This review elaborates synthesis methods and antimicrobial mechanisms of various metal as well as metal oxide nanoparticles for better understanding in order to utilize their potentials in various biomedical applications.

scholarly journals Antimicrobial metal-based nanoparticles: a review on their synthesis, types and antimicrobial action

2020 ◽  
Vol 11 ◽  
pp. 1450-1469
Author(s):  
Matías Guerrero Correa ◽  
Fernanda B Martínez ◽  
Cristian Patiño Vidal ◽  
Camilo Streitt ◽  
Juan Escrig ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Food Packaging ◽  
Antimicrobial Agents ◽  
Cell Damage ◽  
Metal Oxide Nanoparticles ◽  
High Surface ◽  
Antimicrobial Properties ◽  
Antimicrobial Action ◽  
Oxide Nanoparticles ◽  
Synthesis Methods

The investigation of novel nanoparticles with antimicrobial activity has grown in recent years due to the increased incidence of nosocomial infections occurring during hospitalization and food poisoning derived from foodborne pathogens. Antimicrobial agents are necessary in various fields in which biological contamination occurs. For example, in food packaging they are used to control food contamination by microbes, in the medical field the microbial agents are important for reducing the risk of contamination in invasive and routine interventions, and in the textile industry, they can limit the growth of microorganisms due to sweat. The combination of nanotechnology with materials that have an intrinsic antimicrobial activity can result in the development of novel antimicrobial substances. Specifically, metal-based nanoparticles have attracted much interest due to their broad effectiveness against pathogenic microorganisms due to their high surface area and high reactivity. The aim of this review was to explore the state-of-the-art in metal-based nanoparticles, focusing on their synthesis methods, types, and their antimicrobial action. Different techniques used to synthesize metal-based nanoparticles were discussed, including chemical and physical methods and “green synthesis” methods that are free of chemical agents. Although the most studied nanoparticles with antimicrobial properties are metallic or metal-oxide nanoparticles, other types of nanoparticles, such as superparamagnetic iron-oxide nanoparticles and silica-releasing systems also exhibit antimicrobial properties. Finally, since the quantification and understanding of the antimicrobial action of metal-based nanoparticles are key topics, several methods for evaluating in vitro antimicrobial activity and the most common antimicrobial mechanisms (e.g., cell damage and changes in the expression of metabolic genes) were discussed in this review.

scholarly journals A comprehensive review on green synthesis of titanium dioxide nanoparticles and their diverse biomedical applications

2022 ◽  
Vol 11 (1) ◽  
pp. 44-63
Author(s):  
Suresh Sagadevan ◽  
Shahla Imteyaz ◽  
Baranya Murugan ◽  
Jayasingh Anita Lett ◽  
Nanthini Sridewi ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Metal Oxide ◽  
Biomedical Applications ◽  
Titanium Dioxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Cost Effective ◽  
Biological Synthesis ◽  
Synthesis Methods ◽  
Environmental Friendliness ◽  
Environmentally Safe

Abstract Metal oxide nanoparticles (NPs) have found a variety of applications in numerous industrial, medical, and environmental fields s, attributable to recent advances in the nanotechnology field. Titanium dioxide nanoparticles (TiO2-NPs) have gained importance as metal oxide NPs due to their potential in various fields, particularly nanomedicine and other biomedicine fields. Several studies have confirmed that NPs produced via the biosynthesis route using natural resources have significant advantages such as fewer toxic contaminants, less subsequent complex chemical synthesis, environmental friendliness, cost-effectiveness, and stability when compared to NPs produced by conventional methods, and its production with controlled shapes and sizes. Therefore, considerable effort is being expended to implement biological synthesis methods with these proven advantages. TiO2-NPs can be made using a variety of biological, chemical, and physical methods. Physicochemical methods are costly, emit high levels of toxic chemicals into the atmosphere, and consume a lot of energy. On the other hand, the biological approach is an environmentally safe, cost-effective, dependable, convenient, and easy way to synthesize TiO2-NPs. In this review, the bio-mediated synthesis, as well as various biomedical applications of TiO2-NPs, were discussed.

A comparative study of metal oxide nanoparticles embryotoxicity using the embryonic stem cell test

2013 ◽  
Vol 14 (1-2) ◽  
pp. 61-64 ◽  
Author(s):  
Lucia Vecchione ◽  
Micol Massimiani ◽  
Antonella Camaioni ◽  
Luna Sifrani ◽  
Andrea Magrini ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Titanium Dioxide ◽  
Metal Oxide ◽  
Biomedical Applications ◽  
Titanium Dioxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Embryonic Stem ◽  
Oxide Nanoparticles ◽  
Cell Test

AbstractMany in vitro studies demonstrated that metal oxide nanoparticles like zinc oxide and titanium dioxide are versatile platforms for industrial and biomedical applications. In this paper, investigation of the embryotoxic potential of these nanoparticles using the Embryonic stem Cells Test (EST) was evaluated. The EST is a validated in vitro toxicity test used to predict embryotoxicity of soluble chemical compounds, which only recently has been applied to nanoparticles, demonstrating its suitability also in nanotoxicology. Through such test, we were able to classify zinc oxide nanoparticles as not embryotoxic, while titanium dioxide nanoparticles appeared to be weakly embryotoxic.

scholarly journals Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations

2020 ◽  
Vol 8 (10) ◽  
pp. 1545 ◽  
Author(s):  
Liubov Shkodenko ◽  
Ilia Kassirov ◽  
Elena Koshel
Keyword(s):  
Antibiotic Resistance ◽  
Comparative Analysis ◽  
Metal Oxide ◽  
Metal Oxide Nanoparticles ◽  
Antimicrobial Properties ◽  
Bacterial Biofilms ◽  
Oxide Nanoparticles ◽  
Promising Solution ◽  
Low Efficiency ◽  
Al2o3 Nps

At present, there is an urgent need in medicine and industry to develop new approaches to eliminate bacterial biofilms. Considering the low efficiency of classical approaches to biofilm eradication and the growing problem of antibiotic resistance, the introduction of nanomaterials may be a promising solution. Outstanding antimicrobial properties have been demonstrated by nanoparticles (NPs) of metal oxides and their nanocomposites. The review presents a comparative analysis of antibiofilm properties of various metal oxide NPs (primarily, CuO, Fe3O4, TiO2, ZnO, MgO, and Al2O3 NPs) and nanocomposites, as well as mechanisms of their effect on plankton bacteria cells and biofilms. The potential mutagenicity of metal oxide NPs and safety problems of their wide application are also discussed.

Surface coating and functionalization of metal and metal oxide nanoparticles for biomedical applications

2022 ◽  
pp. 205-231
Author(s):  
Raj Kumar ◽  
Guruprasad Reddy Pulikanti ◽  
Konathala Ravi Shankar ◽  
Darsi Rambabu ◽  
Venkateswarulu Mangili ◽  
...  
Keyword(s):  
Metal Oxide ◽  
Surface Coating ◽  
Biomedical Applications ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles

Synthesis and Antimicrobial Properties of Zinc Oxide Nanoparticles

2020 ◽  
Vol 20 (10) ◽  
pp. 5977-5996 ◽  
Author(s):  
Saee Gharpure ◽  
Balaprasad Ankamwar
Keyword(s):  
Zinc Oxide ◽  
Zno Nanoparticles ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Physical Contact ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Promising Alternative

With increase in incidence of multidrug resistant pathogens, there is a demand to adapt newer approaches in order to combat these diseases as traditional therapy is insufficient for their treatment. Use of nanotechnology provides a promising alternative as antimicrobial agents as against traditional antibiotics. Metal oxides have been exploited for a long times for their antimicrobial properties. Zinc oxide nanoparticles (ZnO NPs) are preferred over other metal oxide nanoparticles because of their bio-compatible nature and excellent antibacterial potentials. The basic mechanism of bactericidal nature of ZnO nanoparticles includes physical contact between ZnO nanoparticles and the bacterial cell wall, generation of reactive oxygen species (ROS) as well as free radicals and release of Zn2+ ions. This review focuses on different synthesis methods of ZnO nanoparticles, various analytical techniques frequently used for testing antibacterial properties, mechanism explaining antibacterial nature of ZnO nanoparticles as well as different factors affecting the antibacterial properties.

scholarly journals Mechanochemical synthesis of metal oxide nanoparticles

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Takuya Tsuzuki
Keyword(s):  
Metal Oxide ◽  
Mechanochemical Synthesis ◽  
Large Scale ◽  
Reaction Pathway ◽  
Metal Oxide Nanoparticles ◽  
Energy Storage And Conversion ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Scale Production ◽  
Large Scale Production

AbstractIn the last decades, mechanochemical processing has emerged as a sustainable method for the large-scale production of a variety of nanomaterials. In particular, mechanochemical synthesis can afford well-dispersed metal-oxide nanoparticles, which are used in wide-ranging applications including energy storage and conversion, environmental monitoring, or biomedical uses. This article reviews recent progress in the mechanochemical synthesis of metal-oxide nanoparticles, explores reaction mechanisms, and contrasts the influence of chosen process parameters on the properties of end products. The role of choice of reaction pathway, as well as advantages and limitations compared to other synthesis methods are discussed. A prospect for future development of this synthetic method is proposed.

Metal Oxide Nanoparticles: Potential Uses in Biomedical Applications

2014 ◽  
Vol 11 (2) ◽  
pp. 139-149 ◽  
Author(s):  
Denisa Ficai ◽  
Ovidiu Oprea ◽  
Anton Ficai ◽  
Alina Holban
Keyword(s):  
Metal Oxide ◽  
Biomedical Applications ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles

Green Route for the Fabrication of ZnO Nanoparticles and Potential Functionalization with Chitosan Using Cross-linkers: A Review

2021 ◽  
Vol 3 (1) ◽  
pp. 1-25
Author(s):  
Hemra Hamrayev ◽  
Kamyar Shameli ◽  
Mostafa Yusefi ◽  
Serdar Korpayev
Keyword(s):  
Zinc Oxide ◽  
Metal Oxide ◽  
Green Synthesis ◽  
Zno Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Zno Nps ◽  
Biological Sources ◽  
Physical And Chemical

Zinc oxide is of significant importance for many industries due to its versatile properties, which have been enhanced with the production of this material in the nanoscale. Recent interest in the preparation of metal oxide nanoparticles using biological approaches has been reported in the literature. This technique known as “green synthesis” is an environmentally benign process than conventional methods like physical and chemical synthesis methods. Zinc oxide nanoparticles (ZnO-NPs) have been successfully obtained by green synthesis using different biological substrates like chitosan. Chitosan is biocompatible, biodegradable polymer having exclusive physical and chemical properties. Chitosan/metal oxide nanocomposite is a promising nanomaterial with enhanced properties for multiple functionalities. Therefore, this review discusses favorable approach in the formation of cross-linked Chitosan/ZnO nanocomposites attracting significant attention in various fields such biomedical due to their unique biodegradable, biocompatible, non-toxic nature. The use of biological sources, fabrication of green synthesized ZnO nanoparticles and its applications is briefly discussed. Overall, this review is a comprehensive study for the synthesis of ZnO-NPs using biological sources counting on their features and applications.

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