Can Dietary Polyphenols Prevent the Formation of Toxic Compounds from Maillard Reaction?

2016 ◽  
Vol 17 (6) ◽  
pp. 598-607 ◽  
Author(s):  
Serena Del Turco ◽  
Giuseppina Basta
2012 ◽  
Vol 82 (3) ◽  
pp. 228-232 ◽  
Author(s):  
Mauro Serafini ◽  
Giuseppa Morabito

Dietary polyphenols have been shown to scavenge free radicals, modulating cellular redox transcription factors in different in vitro and ex vivo models. Dietary intervention studies have shown that consumption of plant foods modulates plasma Non-Enzymatic Antioxidant Capacity (NEAC), a biomarker of the endogenous antioxidant network, in human subjects. However, the identification of the molecules responsible for this effect are yet to be obtained and evidences of an antioxidant in vivo action of polyphenols are conflicting. There is a clear discrepancy between polyphenols (PP) concentration in body fluids and the extent of increase of plasma NEAC. The low degree of absorption and the extensive metabolism of PP within the body have raised questions about their contribution to the endogenous antioxidant network. This work will discuss the role of polyphenols from galenic preparation, food extracts, and selected dietary sources as modulators of plasma NEAC in humans.


Author(s):  
John O'Brien ◽  
Harry E. Nursten ◽  
M. James C. Crabbe ◽  
Jennifer M. Ames
Keyword(s):  

2012 ◽  
Vol 1 (5) ◽  
pp. 115-117
Author(s):  
Jahnavi KRM Jahnavi KRM ◽  
◽  
Raghavendra Rao K ◽  
Padma Suvarna R

1971 ◽  
Vol 6 (1) ◽  
pp. 53-79
Author(s):  
Vaclav Kresta ◽  
Gerald B. Ward

Abstract At many mining sites process (milling) and drainage waters escape treatment and cause receiving waters to become contaminated above avoidance or even toxic levels for fish. The present know-how on chemical agents which can be used to complex with copper and zinc to form non-toxic compounds is limited to chelating agents such as NTA or EDTA. Preferential reaction with trivalent ions such as iron means that such ions must be tied up before complexation of copper and zinc can occur. As the amount of iron in contaminated water is usually two to eight times higher than that of copper and zinc, high dosages of chelating agents are usually required. In this project, the use of salts of anthranilic acid, especially calcium anthranilate, was investigated. The consumption of anthranilateions was found to be about the same as that of NTA or EDTA, i.e. four milligrams per milligram of copper or zinc. The total dosage to be applied to contaminated waters would be, however, several times lower as iron is not involved in the reactions and copper and zinc are complexed in that order. Toxicity tests to compare the efficiency and dasages of calcium anthranilate and NTA or EDTA are presently being carried out.


2014 ◽  
Vol 15 (4) ◽  
pp. 343-351 ◽  
Author(s):  
Cinta Blade ◽  
Laura Baselga-Escudero ◽  
Anna Arola-Arnal

2020 ◽  
Vol 20 (15) ◽  
pp. 1532-1542 ◽  
Author(s):  
Miroslav Pohanka

Inhibitors of cholinesterases are a wide group of low molecular weight compounds with a significant role in the current pharmacology. Besides the pharmacological importance, they are also known as toxic compounds like military nerve agents. In the pharmacology, drugs for Alzheimer disease, myasthenia gravis and prophylaxis of poisoning by nerve agents can be mentioned as the relevant applications. Besides this, anti-inflammation and antiphrastic drugs are other pharmacological applications of these inhibitors. This review is focused on a survey of cholinesterase inhibitors with known or expected pharmacological impact and indications of their use. Recent literature with comments is provided here as well.


2019 ◽  
Vol 15 (2) ◽  
pp. 143-151 ◽  
Author(s):  
Parviz Norouzi ◽  
Bagher Larijani ◽  
Taher Alizadeh ◽  
Eslam Pourbasheer ◽  
Mostafa Aghazadeh ◽  
...  

Background: The new progress in electronic devices has provided a great opportunity for advancing electrochemical instruments by which we can more easily solve many problems of interest for trace analysis of compounds, with a high degree of accuracy, precision, sensitivity, and selectivity. On the other hand, in recent years, there is a significant growth in the application of nanomaterials for the construction of nanosensors due to enhanced chemical and physical properties arising from discrete modified nanomaterial-based electrodes or microelectrodes. Objective: Combination of the advanced electrochemical system and nanosensors make these devices very suitable for the high-speed analysis, as motioning and portable devices. This review will discuss the recent developments and achievements that have been reported for trace measurement of drugs and toxic compounds for environment, food and health application.


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