Optimization of Crude Polysaccharides Extraction from Plantago ovata Forsk Seed by Response Surface Methodology

2020 ◽  
Vol 16 (3) ◽  
pp. 354-363
Author(s):  
Ehsan Sadeghi ◽  
Reza Mohammadi ◽  
Mohammad H. Shirgardoun ◽  
Fatemeh Askari ◽  
Masoumeh Taghizadeh ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Food Packaging ◽  
Polynomial Equation ◽  
Edible Films ◽  
Extraction Yield ◽  
Raw Material ◽  
Extraction Time ◽  
Extraction Temperature ◽  
Plantago Ovata

Background: Plantago ovata Forsk (Psyllium seed) is an annual plant of plantago genus. This plant widely grows in India and Iran. The Psyllium seed contains mucilage, protein, sugar, fat and tannins. Seed’s husk is a known source to extract hydrocolloid. Objective: The aim of this study was to optimize gum extraction from the Psyllium seed. Methods: The response surface methodology (RSM) was used to estimate the effect of independent variables on the extraction yield of Psyllium gum. The obtained experimental data were fitted to a second- order polynomial equation using multiple regression analysis and analyzed by appropriate statistical methods. A central composite design (CCD) was used for experimental design and analysis of the results to obtain the best possible combination of extraction temperature (X1= 60-80°C), extraction time (X2= 1-3 h), and the ratio of water to raw material (X3= 30-70%) for the maximum gum extraction. Results: Optimum extraction conditions were extraction temperature of 79°C, extraction time of 2.5 h, and the ratio of water to the raw material of 57%. The experimental extraction yield under optimal conditions was found to be 9 ± 0.25%, which was in agreement with the predicted value of 9.4%. Conclusion: This study showed that Psyllium gum can be used as a hydrocolloid source for pharmaceutical and food industry such as edible films for food packaging.

Response Surface Methodology for Optimization of the Ultrasonic Extraction of Polysaccharides from Melaleuca ahemifolia

2013 ◽  
Vol 655-657 ◽  
pp. 1987-1995
Author(s):  
Yue Xiao ◽  
He Ping Yu ◽  
Li Jing Lin
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Polynomial Equation ◽  
Extraction Yield ◽  
Raw Material ◽  
Extraction Time ◽  
Ultrasonic Power ◽  
Ultrasonic Assisted ◽  
Experimental Yield ◽  
Optimum Extraction

An ultrasonic-assisted procedure for the extraction of polysaccharides from Melaleuca ahemifolia was investigated using response surface methodology (RSM). A Box–Behnken design (BBD) was employed to investigate the effects of extraction time, ratio of water to raw material and ultrasonic power on the extraction yield of polysaccharides.The statistical analysis indicated that three variables and the quadratic terms had significant effects on the yield (p＜0.05). The experimental data obtained were fitted to a second-order polynomial equation using multiple regression analysis and further analyzed by appropriate statistical methods (ANOVA). The optimum extraction conditions were as follows: extraction time of 21 min, ratio of water to raw material of 40, ultrasonic power of 170 W. Under the optimization conditions, the experimental yield of polysaccharides was 6.194%, which was in good agreement with the predicted value (6.288%).

scholarly journals Homogenate Extraction of Crocins from Saffron Optimized by Response Surface Methodology

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Yingpeng Tong ◽  
Yu Jiang ◽  
Dan Guo ◽  
Yongqiu Yan ◽  
Shiping Jiang ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Ethanol Concentration ◽  
Extraction Yield ◽  
Extraction Time ◽  
Process Conditions ◽  
Extraction Temperature ◽  
Single Factor ◽  
Extraction Voltage ◽  
Homogenate Extraction

Saffron, which has many kinds of biological activities, has been widely used in medicine, cosmetics, food, and other fields of health promotion industries. Crocins are the main component of saffron (Crocus sativus L.). At present, most of the extraction methods for crocins require long time or special instruments to complete the process and some of them are not suitable for industrial production at present. In this article, homogenate extraction technology which is a convenient and efficient method was developed for crocins extraction from saffron. Firstly, the influences of extraction voltage, extraction time, ethanol concentration, and temperature on crocins yield were studied by single factor experiments; and then response surface methodology (RSM) was used to optimize levels of four variables based on the result of single factor experiments. Results showed that the optimum extraction process conditions for crocins were as follows: extraction voltage, 110 V; ethanol concentration, 70%; extraction temperature, 57°C; and extraction time, 40 s. Based on these conditions, the extraction yield of crocins can reach 22.76% which is higher than ultrasonic extraction method. Therefore, homogenate extraction is an effective way to extract crocins from saffron with higher extraction yield and shorter extraction time.

Optimization of the Ultrasonic Extraction of Gypenoside III from Gynostemma pentaphyllum by Response Surface Methodology

2012 ◽  
Vol 550-553 ◽  
pp. 1866-1870
Author(s):  
Xiao Dan Tang ◽  
Hai Yang Hang ◽  
Shao Yan Wang ◽  
Jing Xiang Cong
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Extraction Yield ◽  
Raw Material ◽  
Extraction Temperature ◽  
Optimal Conditions ◽  
Gynostemma Pentaphyllum ◽  
Bioactive Component ◽  
Yield Value ◽  
Ultrasonic Time

Gypenosides III is a major bioactive component which is rich in Gynostemma pentaphyllum. For better utilization of the native resource, response surface methodology was used to optimize the extraction conditions of gypenosides III from G. pentaphyllum. The effects of three independent variables on the extraction yield of gypenosides III were investigated and the optimal conditions were evaluated by means of Box-Behnken design. The optimal conditions are as follows: ratio of ethanol to raw material 25, extraction temperature 58°C and ultrasonic time 25min. Under these conditions, the yield of gypenoside III is 1.216±0.05%, which is agreed closely with the predicted yield value.

scholarly journals Optimization of Supercritical Carbon Dioxide Extraction of Quercus infectoria Oil

2015 ◽  
Vol 74 (7) ◽  
Author(s):  
Liza Md Salleh ◽  
Stashia ELeaness Rosland Abel ◽  
Gholamreza Zahedi ◽  
Russly Abd Rahman ◽  
Hasmida Mohd Nasir ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Goodness Of Fit ◽  
Maximum Yield ◽  
Extraction Yield ◽  
Extraction Time ◽  
Extraction Temperature ◽  
Predicted Values ◽  
Artificial Neural Network Ann ◽  
Quercus Infectoria

This current study focuses on the modelling and optimization of supercritical fluid extraction of Quercus infectoria galls oil. In this case, response surface methodology (RSM) and artificial neural network (ANN) were applied for the modelling and prediction of extraction yield of galls oil. A 17-run Box-Behnken Design (BBD) was employed to statistically optimize the process parameters of SC-CO2 extraction of Quercus infectoria galls at a condition as follows: pressure (5000, 6000, 7000 Psi), temperature (40, 50, 60°C) and extraction time (30, 45, 60 min). The maximum yield of the extracted oil is1.12 % and the optimum conditions are at an extraction pressure of 5574 Psi; extraction temperature of 75°C and extraction time of 54 min. Under the optimal conditions, the experimental results agree with the predicted values obtained through analysis of variance (ANOVA). This indicates a successful response surface methodology and highly satisfactory goodness of fit of the model used. The analysis of experimental design for process optimization results demonstrates that temperature and extraction time are the main parameters that influence the oil extraction of Quercus infectoria.

scholarly journals OPTIMIZATION CONDITION EXTRACTION USED ENZYME WITH RESPONSE SURFACE METHODOLOGY TO EXTRACT ROSELLE PETALS (Hibiscus sabdariffa L.)

2019 ◽  
Vol 9 (2) ◽  
Author(s):  
Mardiah Mardiah ◽  
Rima Nidaul Hasanah ◽  
Noli Novidahlia ◽  
A.E. Zainal Hasan
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Enzyme Concentration ◽  
Raw Material ◽  
Extraction Time ◽  
Anthocyanin Content ◽  
Extraction Temperature ◽  
Hibiscus Sabdariffa ◽  
Cellulase Enzymes ◽  
Yield Level

Roselle petals can be made into extracts as a source of raw material for food products and other products. Previous research states that the use of pectinase and cellulase enzymes can increase the yield including the anthocyanin content. This study aims to optimize the extraction conditions of roselle flower petals  (Hibiscus sabdariffa L.) using pectinase and cellulase enzymes by using Response Surface Methodology (RSM). The treatment conditions were using pectinase and cellulase enzyme (1: 1) with concentrations in the range between 500-1500 ppm, extraction temperature between 35-65 oC and extraction time between 30-90 minutes. Analysis of the best treatment was carried out on the yield level, anthocyanin content and total dissolved solids tested using central composite design, obtained R2 values for the three responses of 0.6. The results showed that based on the surface response, the optimum conditions of the best  extraction of the rosella at the addition of enzyme concentration of 1000 ppm, extraction temperature of 50 oC and extraction time of 10 minutes. In this condition, the yield of dried extracts of rosella was 84,20%, anthocyanins content 479,70 mg/L and total soluble solid 2,13 oBrix.

Optimization of Extraction Process of Lycopene from Watermelon (Citrullus lanatus) by Response Surface Methodology

2011 ◽  
Vol 140 ◽  
pp. 385-393 ◽  
Author(s):  
Xian Feng Shi ◽  
Yuan Xu ◽  
Yu Hua Li ◽  
Hong Xia Zeng ◽  
Yu Hong Sun
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Citrullus Lanatus ◽  
Extraction Process ◽  
Quadratic Equation ◽  
Raw Material ◽  
Extraction Time ◽  
Solvent Ratio ◽  
Extraction Temperature ◽  
Extraction Solvent

The extraction processing of lycopene from watermelon was investigated in this paper. Based on single factor experiments, response surface methodology (RSM) was adopted to study the key parameters such as number of extraction, extraction temperature, extraction time in order to increase extraction rate of lycopene. A second order quadratic equation was established and the applicability of model and interaction involved factors on predicting the lycopene extracting content was verified. The results indicated that the optimum extraction conditions were hexane (containing 2% dichloromethane) as extraction solvent, ratio of solvent to raw material of 3:1 (mL/g), number of extraction of 2, extraction time of 1.9 h and extraction temperature of 29.8°C. Under these conditions the extracting content of lycopene was 14.71±0.22 mg/kg, which is well in agreement with value predicted by the model.

scholarly journals Optimization of extraction technology of polysaccharide from foxtail millet using response surface methodology

2014 ◽  
Vol 20 (4) ◽  
pp. 579-585 ◽  
Author(s):  
Ai-Shi Zhu ◽  
Jin-Na Ye ◽  
Fei-Na Yan
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Foxtail Millet ◽  
Polynomial Equation ◽  
Extraction Time ◽  
Extraction Temperature ◽  
Extraction Technology ◽  
Solid Ratio ◽  
Experimental Yield ◽  
Optimum Extraction

The experiment of extraction of polysaccharide from foxtail millet was investigated. Response Surface Methodology (RSM),based on a threelevel, three variablesBox-Behnken design (BBD), was employed to obtain the best possible combination of liquid-solid ratio(X1: 15.0-25.0 mL?g-1),extraction time (X2: 1.5-2.5h), and extraction temperature (X3: 65.0-75.0?C)for maximum polysaccharide yields. The experimental data obtained were fitted to a second-order polynomial equation using multiple regression analysis and also analyzed by appropriate statistical methods (ANOVA). The optimum extraction conditions were as follows: liquid-solid ratio 20.7mL?g-1, extraction time 2.0h, extraction temperature 72.3?C. Under these conditions, the experimental yield was 8.08mg?g-1, which is well in close agreement with8.02mg?g-1predicted value by the model.

Optimization of Extraction Process by Response Surface Methodology of Polysaccharides from Acanthopanax obouatus Hoo

2012 ◽  
Vol 512-515 ◽  
pp. 2386-2389
Author(s):  
Xiao Rong Li ◽  
Peng Zhao
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Extraction Process ◽  
Raw Material ◽  
Extraction Time ◽  
Extraction Temperature ◽  
Predicted Values

Polysaccharide from Acanthopanax obouatus Hoo(AHPs) was extracted with the hot water.Box-Behnken design(BBD) was employed to optimize extraction temperature; extraction time and ratio of water to raw material to obtain a high AHPs yield. The yield of polysaccharide was 4.68% based on the above mentioned conditions.Close agreement between experimetal and predicted values was found.

Optimization of Extraction of Tannins from Banana Peel Using Response Surface Methodology

2014 ◽  
Vol 678 ◽  
pp. 566-571
Author(s):  
Ting Ru Wu ◽  
Hong Ling Wang ◽  
Shi Wen Jiang ◽  
Dan Dan Liu ◽  
Fei Wei
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Ethanol Concentration ◽  
Extraction Yield ◽  
Extraction Time ◽  
Banana Peel ◽  
Extraction Temperature ◽  
Liquid Ratio ◽  
Optimized Conditions ◽  
Tannin Extraction

Response surface methodology (RSM) was employed to optimize the extraction conditions of tannins from banana peels. Based on the single-factor experiments, four independent variables including ethanol concentration, solid to liquid ratio, extraction time and extraction temperature were selected as affecting factors. According to central composite design (CCD) the four factor, five levels experiments were carried out with the tannin extraction yield as evaluation index. The results show that the optimized conditions are as follows: ethanol concentration of 75.44%, solid to liquid ratio of 1:35.34, extraction time of 7.94 h, extraction temperature of 62.85°C. Under the optimized conditions, the predicted tannin extraction yield reaches 58.55%, while the actual extraction yield is 57.42% with the relative error of 1.13%.

EXTRACTION OPTIMIZATION OF THREE INDEPENDENT VARIABLES OF ANTIOXIDANTS FROM BASIL LEAVES USING RESPONSE SURFACE METHODOLOGY

INDIAN DRUGS ◽  
2020 ◽  
Vol 57 (04) ◽  
pp. 20-28 ◽  
Author(s):  
Sulaiman M. Alnasser ◽  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Radical Scavenging ◽  
Extraction Yield ◽  
Extraction Time ◽  
Total Phenolic ◽  
Extraction Temperature ◽  
Optimum Conditions ◽  
Antioxidant Power ◽  
Independent Variables

The current study reports the antioxidant activity of Ocimum basilicum. Central composite design (CCD) was used to study the effect of variables on the extraction using magnetic stirrer (MST). Three independent variables including temperature, extraction speed, and extraction time were studied that optimize particular responses of total phenolic content, ferric reducing antioxidant power (FRAP), and DPPH free radical scavenging activity. The effect of the extraction temperature on extraction process was investigated in the range from 26.3oC to 93.6oC, extraction time, from 1 to 30 h, and extraction speed, in the range from 263 to 936 rpm. The extraction yield was significantly (P < 0.05) affected by all the variables. Temperature and extraction speed were found to have a marked effect while the extraction time was found to have possible minor effects. Graphical optimization determined the optimum conditions for the extraction. The optimum condition predicted an extraction yield of 20.49g/100g at 75.33oC for five hours at 73 rpm. Optimum conditions were determined to obtain highest extraction yield. Results showed that water/seed ratio was the most significant parameter, followed by temperature and time. All quantitative modeling and response surface methodology recommended that extraction temperature and time were the most effective parameters of MST process. However, extraction time was found out to be an insignificant factor in MST extraction of antioxidant and total phenolic compounds of O. basilicum.

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