scholarly journals Surface Modification of SUS 316L Stainless Steel with Tartaric Acid Derivative-Crosslinked Human Serum Albumin Matrices

2008 ◽  
Vol 2 (1) ◽  
pp. 143-147 ◽  
Author(s):  
Sachiro Kakinoki ◽  
Yasuyuki Katada ◽  
Yoshiyuki Uchida ◽  
Tetsushi Taguchi
Keyword(s):  
Stainless Steel ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Tartaric Acid ◽  
Acid Derivative ◽  
Photoelectron Spectroscopy ◽  
Sodium Dodecyl ◽  
Contact Angle Measurement ◽  
Angle Measurement

The surface of stainless steel (SUS316L) was modified by alternating immersion in a solution of human serum albumin (HSA) and solution of a tartaric acid derivative (TAD). The resulting HSA/TAD-immobilized SUS316L was characterized by means of contact-angle measurement, attenuated total-reflectance Fourier-transform infrared spectroscopy, atomic force microscopy, and X-ray photoelectron spectroscopy. A HSA/TAD layer was formed on the surface of SUS316L, the thickness of which increased with increasing numbers of cycles of alternating immersion in the two solutions. The HSA/TAD layer on SUS316L was stable to washing in 1 M NaCl or 5 vol% sodium dodecyl sulfate, showing that the layer was immobilized by covalent bonding rather than electrostatic or hydrophobic interaction. The presence of the HSA/TAD layer on the SUS316L suppressed the formation of a fibrin network. Alternating immersion in solutions of HSA and TAD is a useful technique for functionalizing the surfaces of metals.

In vivoevaluation of bonding ability and biocompatibility of a novel biodegradable glue consisting of tartaric acid derivative and human serum albumin

2009 ◽  
Vol 90A (2) ◽  
pp. 543-548 ◽  
Author(s):  
Masashi Iwasashi ◽  
Masataka Sakane ◽  
Hirofumi Saito ◽  
Tetsushi Taguchi ◽  
Tetsuya Tateishi ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Tartaric Acid ◽  
Acid Derivative

Rapid detection and initial characterization of genetic variants of human serum albumin

1991 ◽  
Vol 37 (7) ◽  
pp. 1221-1224 ◽  
Author(s):  
J Merle Sheat ◽  
Robert J Peach ◽  
Peter M George
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Genetic Variants ◽  
Gel Electrophoresis ◽  
Structural Changes ◽  
Polyacrylamide Gel Electrophoresis ◽  
Sodium Dodecyl

Abstract We have studied the detection and classification of genetic variants of human serum albumin by electrophoresis. Samples from 10 patients who were heterozygous for eight different albumin variants were studied by two methods. In agarose gel electrophoresis, each of these variants has an abnormal mobility and can be classified on the basis that structural changes at the N-terminus abolish 63Ni binding. In sodium dodecyl sulfate-polyacrylamide gel electrophoresis of whole serum, glycosylated variants are easily detected because of their greater apparent molecular mass.

Binding of toluidine blue-myristic acid derivative to cucurbit[7]uril and human serum albumin: computational and biophysical insights towards a biosupramolecular assembly

2022 ◽  
Author(s):  
Felipe Andrade-Villalobos ◽  
Daniel Zúñiga-Núñez ◽  
Angelica Fierro ◽  
Denis Fuentealba
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Acid Derivative ◽  
Toluidine Blue ◽  
Myristic Acid

A new toluidine blue-myristic acid photosensitizer derivate (TBOMyr) was investigated as a design molecule to bind simultaneously to cucurbit[7]uril (CB[7]) and human serum albumin (HSA) with the aim of constructing...

scholarly journals The cleaning and disinfection by heat of bedpans in automatic and semi-automatic machines

1976 ◽  
Vol 76 (3) ◽  
pp. 341-348 ◽  
Author(s):  
A. B. M. G. Mostafa ◽  
K. F. Chackett
Keyword(s):  
Stainless Steel ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
General Hospital ◽  
Test Machine ◽  
Streptococcus Faecalis ◽  
Technetium 99M ◽  
Biological Contaminant ◽  
Cleaning And Disinfection

SUMMARYThis work is concerned with the cleaning and disinfection by heat of stainless-steel and polypropylene bedpans, which had been soiled with either a biological contaminant, human serum albumin (HSA) labelled with technetium-99m 99m(Tc), or a bacteriological contaminant, streptococcus faecalis mixed with Tc-labelled HSA. Results of cleaning and disinfection achieved with a Test Machine and those achieved by procedures adopted in eight different wards of a general hospital are reported. Bedpan washers installed in wards were found to be less efficient than the Test Machine, at least partly because of inadequate maintenance. Stainless-steel and polypropylene bedpans gave essentially the same results.

Development of Biocompatible Glues for Minimum Invasive Therapy

2007 ◽  
Vol 330-332 ◽  
pp. 1339-1342 ◽  
Author(s):  
Tetsushi Taguchi ◽  
H. Saito ◽  
Masashi Iwasashi ◽  
Masataka Sakane ◽  
S. Kakinoki ◽  
...  
Keyword(s):  
Citric Acid ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fibrin Glue ◽  
Acid Derivative ◽  
Bonding Strength ◽  
Wound Closure ◽  
Mouse Skin ◽  
Carbodiimide Hydrochloride

A biocompatible glue consisting of human serum albumin (HSA) and citric acid derivative (CAD), named CAD-A glue was developed. CAD was successfully synthesized by the reaction between citric acid and N-hydroxysuccinimide in the presence of 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide hydrochloride. When the CAD-A glue was applied to the collagenbased casings, it took 7 min to obtain half of maximum bonding strength (760 g/cm2). The bonding strength of this glue to collagen-based casings increased with increasing of HSA concentration.The bonding strength of CAD-A glue increased with increasing CAD concentration up to 200 mM, and then decreased with increasing CAD concentration under the fixed HSA concentration (50 w/w%). The CAD-A glue showed excellent wound closure ability rather than fibrin glue when applied to the mouse skin. These results suggested that this developed glue had both tissue compatibility and bonding strength for use in clinical field.

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