scholarly journals Population-Based Age Group Specific Annual Incidence Rates of Symptomatic Age-Related Macular Degeneration

2014 ◽  
Vol 8 (1) ◽  
pp. 95-100 ◽  
Author(s):  
Jukka M Saari
Keyword(s):  
Macular Degeneration ◽  
Population Based ◽  
Incidence Rates ◽  
Annual Incidence ◽  
Age Related Macular Degeneration ◽  
Age Group ◽  
Population Based Study ◽  
Hospital District ◽  
Age Related ◽  
One Year

Purpose To study the population-based annual incidence rates of exudative, dry and all cases of symptomatic age-related macular degeneration (AMD) in different age and sex groups. Methods. This is a one year, prospective, population-based study on all consecutive new patients with AMD in the hospital district of Central Finland. The diagnosis was confirmed in all patients with slit lamp biomicroscopy, optical coherence tomography (OCT) using a Spectralis HRA + OCT device, and the Heidelberg Eye Explorer 1.6.2.0 program. Fluorescein angiograms were taken when needed. Results. The population-based annual incidence rates of all cases of symptomatic AMD increased from 0.03% (95% CI, 0.01-0.05%) in the age group 50-59 years to 0.82% (95% CI, 0.55-1.09%) in the age group 85-89 years and were 0.2% (95% CI, 0.17-0.24%) in exudative, 0.11% (95% CI, 0.09-0.14%) in dry, and 0.32% (95% CI, 0.28-0.36%) in all cases of AMD in the age group 60 years and older. During the next 20 years in Central Finland the population-based annual incidence rates can be estimated to increase to 0.27% (95% CI, 0.24-0.30%) in exudative, to 0.13% (95% CI, 0.11-0.15%) in dry, and to 0.41% (95% CI, 0.37-0.45%) in all cases of AMD in the age group 60 years and older. The population-based annual incidence of AMD did not show statistically significant differences between males and females (p>0.1). Conclusion: The population-based age-group specific annual incidence rates of symptomatic AMD of this study may help to plan health care provision for patients of AMD.

A Population-based Study on the Prevalence and Associated Factors of Age-related Macular Degeneration in Northern Iran the Gilan Eye Study

2020 ◽  
Vol 27 (3) ◽  
pp. 209-218
Author(s):  
Hassan Behboudi ◽  
Homayoun Nikkhah ◽  
Yousef Alizadeh ◽  
Marzieh Katibeh ◽  
Mojgan Pakbin ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Associated Factors ◽  
Population Based ◽  
Age Related Macular Degeneration ◽  
Northern Iran ◽  
Population Based Study ◽  
Age Related

scholarly journals Association between psoriasis and neovascular age-related macular degeneration: A population-based study

2015 ◽  
Vol 72 (6) ◽  
pp. 1090-1092 ◽  
Author(s):  
Li-Ting Kao ◽  
Kuo-Hsien Wang ◽  
Herng-Ching Lin ◽  
Ming-Chieh Tsai ◽  
Shiu-Dong Chung
Keyword(s):  
Macular Degeneration ◽  
Population Based ◽  
Age Related Macular Degeneration ◽  
Population Based Study ◽  
Age Related

Population-Based Study of Early Age-Related Macular Degeneration

Ophthalmology ◽  
2007 ◽  
Vol 114 (1) ◽  
pp. 99-103 ◽  
Author(s):  
Nicole Tedeschi-Blok ◽  
Jonathan Buckley ◽  
Rohit Varma ◽  
Timothy J. Triche ◽  
David R. Hinton
Keyword(s):  
Macular Degeneration ◽  
Population Based ◽  
Age Related Macular Degeneration ◽  
Early Age ◽  
Population Based Study ◽  
Age Related

Association between cardiorespiratory fitness and handgrip strength with age-related macular degeneration: a population-based study

2020 ◽  
pp. bjophthalmol-2020-316255
Author(s):  
Andreas Katsimpris ◽  
Clemens Jürgens ◽  
Lisa Lüdtke ◽  
Martin Bahls ◽  
Till Ittermann ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
Macular Degeneration ◽  
Cardiorespiratory Fitness ◽  
Handgrip Strength ◽  
Cardiopulmonary Exercise Testing ◽  
Population Based ◽  
Age Related Macular Degeneration ◽  
Fundus Photography ◽  
Population Based Study ◽  
Age Related

AimTo assess whether cardiorespiratory fitness (CRF) and handgrip strength, two objective markers of physical fitness, are associated with age-related macular degeneration (AMD).MethodsWe analysed cross-sectional data from the population-based Study of Health in Pomerania (2008–2012) including 1173 adult men and women aged 20–79 years. Fundus photography of the central retina was recorded with a non-mydriatic camera, and images were graded according to an established clinical AMD classification scale by an experienced reader. CRF was measured using peak oxygen uptake (peakVO2), oxygen uptake at the anaerobic threshold (VO2@AT), and maximum power output (Wmax) from standardised cardiopulmonary exercise testing on a bicycle ergometer according to a modified Jones protocol. Handgrip strength was assessed using a handheld dynamometer. Adjusted prevalence ratios (PR) for the associations of peakVO2, VO2@AT, Wmax and handgrip strength with AMD were derived from multivariable Poisson regression models.ResultsPeakVO2, VO2@AT, Wmax and handgrip strength were not associated with AMD. Adjusted PR for AMD associated with a 1-SD increment in peakVO2, VO2@AT, Wmax and handgrip strength were 1.05 (95% CI 0.82 to 1.34), 0.96 (95% CI 0.78 to 1.18), 1.10 (95% CI 0.86 to 1.41) and 1.01 (95% CI 0.79 to 1.30), respectively. These associations were not modified by age, sex, smoking, body mass index and diabetes. Estimates in sensitivity analysis for confounding, selection bias and missing data were similar.ConclusionIn our study, CRF and handgrip strength were not associated with AMD. Nevertheless, longitudinal studies with bigger sample sizes are needed to furtherly examine these associations.

scholarly journals Increased risk of Alzheimer’s disease among patients with age-related macular degeneration: A nationwide population-based study

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0250440
Author(s):  
Li-Yen Wen ◽  
Lei Wan ◽  
Jung-Nien Lai ◽  
Chih Sheng Chen ◽  
Jamie Jiin-Yi Chen ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Macular Degeneration ◽  
Population Based ◽  
Age Related Macular Degeneration ◽  
Chronic Obstructive ◽  
Research Database ◽  
Age Group ◽  
Age Related ◽  
Increased Risk

Objective This study aimed to investigate the risk of Alzheimer’s disease among patients with age-related macular degeneration and its association with confounding comorbidities. Method This was a population-based, retrospective cohort study. By accessing data from the National Health Insurance Research Database of Taiwan, we identified 10,578 patients aged 50–100 years who were newly diagnosed with age-related macular degeneration between 2000 and 2012 and 10,578 non- age-related macular degeneration individuals. The comorbidities assessed were osteoporosis, diabetes, cirrhosis, cerebrovascular disease, chronic kidney disease, hypertension, hyperlipidemia, coronary artery disease, and chronic obstructive pulmonary disease. Results Patients with age-related macular degeneration had a 1.23-fold increased risk of their condition advancing to Alzheimer’s disease (aHR = 1.23, 95% CI = 1.04–1.46). The younger patients were diagnosed with age-related macular degeneration, the more likely patients got Alzheimer’s disease (50–64 age group: aHR = 1.97, 95% CI = 1.04–3.73; 65–79 age group: aHR = 1.27, 95% CI = 1.02–1.58; 80–100 age group: aHR = 1.06, 95% CI = 0.78–1.45). In addition, there were significantly higher risks of Alzheimer’s disease for patients with cirrhosis (aHR = 1.50, 95% CI = 1.09–2.06) in the age-related macular degeneration cohort than in the non-age-related macular degeneration cohort. Conclusion Patients with age-related macular degeneration may exhibit a higher risk of Alzheimer’s disease than people without age-related macular degeneration.

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