scholarly journals Assessment of Vitamin D Status Among Cases with Pityriasis Alba

2019 ◽  
Vol 13 (1) ◽  
pp. 19-22
Author(s):  
Wisam Majeed Kattoof ◽  
Ahmed Abdulhussein Kawen
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Active Form ◽  
Serum Levels ◽  
Melanin Synthesis ◽  
Vitamin D Status ◽  
Large Samples ◽  
Vitamin D Levels ◽  
The Status ◽  
Apoptotic Activity

Background: Pityriasis alba, is a common benign skin disease occurring predominantly among children, often on their face. Clinically, the spots of pityriasis alba are off-white in color, round with poorly defined margins that bear scanty fine scales on it. No specific cause of pityriasis alba has been identified . In this disease, the number of melanocytes declines and melanosomes reduce within melanocytes. Vitamin D exerts its effect via the vitamin D receptor on melanocytes, if intracellular Ca2+ level decreases, this leads to high levels of reduced thioredoxin this, in turn, inhibit tyrosinase activity with the inhibition of melanin synthesis. In addition, the apoptotic activity of melanocytes reduces by the active form of vitamin D. Aim: The study aimed to assess the status of vitamin D for patients with pityriasis alba. Materials and Methods: 44 patient diagnosed with pityriasis alba were enrolled and the second group of 44 controls was involved in our study. Serum levels of circulating 25 (OH) D were measured. Results: None of the cases had sufficient serum level; the level ranged between 8.1-27.3 ng/ml. The patients had lower circulating vitamin D levels than controls. Conclusion: Our findings in the present study are significant, but further studies with large samples are needed to correlate the extent and severity of pityriasis alba with vitamin D deficiency.

scholarly journals SCREENING FOR VITAMIN D, CALCIUM AND THYROID HORMONE SERUM LEVELS IN HEALTHY ADULT LIBYAN FEMALES

2020 ◽  
Vol 8 (12) ◽  
pp. 483-487
Author(s):  
Rehab R Walli ◽  
◽  
Amal A Ammar ◽  
Rema A Abojarida ◽  
◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Thyroid Hormones ◽  
Vitamin D Deficiency ◽  
Healthy Adult ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
The Status

Vitamin D deficiency is becoming endemic in many parts of the world.Several studies demonstrated a relationship between vitamin D deficiency, hypocalcemia and thyroid disorders. The purpose of this study was to examine the serum level of Vitamin D in healthy adult Libyan women and the status ofserum calcium and thyroid hormones. Serum vitamin D levels were measured in 174 healthy women who are classified in groups according to the age(Mean age 34±14 years). Our results revealed that vitamin D deficiency is very common among Libyan adult females because the mean of vitamin D was 13.4 ± 6.4 (n=174). Vitamin D deficiency was considered at serum levels lower than 20 ng/ml.In addition, we evaluated serum level ofcalcium and Thyroidfunction hormones (TSH, T3 and T4) in only60participants from 174 who are included in this study.It has been previously shown that individuals with low vitamin D levels have low thyroid functionbut our results here indicated that serum thyroid hormones and calcium analysis were lay within the normal rang in most of the participants. Therefore, we strongly recommend the screening for Vitamin D deficiency in all adult Libyan females and encourage the advisability of increasing vitamin D intake combined with following up its serum level to avoid over dose.

Serum levels of 25(OH)D are not associated with venous thromboembolism in the elderly population

2016 ◽  
Vol 115 (01) ◽  
pp. 169-175 ◽  
Author(s):  
Aurélien Delluc ◽  
Marie-Pierre Moineau ◽  
Cécile Tromeur ◽  
Maelenn Gouillou ◽  
Karine Lacut ◽  
...  
Keyword(s):  
Vitamin D ◽  
Venous Thromboembolism ◽  
Seasonal Variations ◽  
Elderly Population ◽  
Serum Levels ◽  
The Elderly ◽  
Vitamin D Status ◽  
Increased Risk ◽  
Vitamin D Levels ◽  
Walking Capacity

SummaryThe prevalence of both vitamin D deficiency and venous thromboembolism (VTE) is important in the elderly. Previous studies have provided evidence for a possible association between vitamin D status and the risk of VTE. Thus, we aimed to investigate the association between vitamin D levels and VTE in the population aged 75 and over included in the EDITH case-control study. The association between vitamin D status and VTE was analysed. We also analysed the monthly and seasonal variations of VTE and vitamin D. Between May 2000 and December 2009, 340 elderly patients (mean age 81.5 years, 32 % men) with unprovoked VTE and their controls were included. The univariate and multivariate analysis found no significant association between serum levels of vitamin D and the risk of unprovoked VTE. In the unadjusted analysis, a higher BMI was statistically associated with an increased risk of VTE (OR 1.09; 95 % CI 1.05–1.13) whereas a better walking capacity and living at home were associated with a decreased rate of VTE: OR 0.57; 95 % CI 0.36–0.90 and 0.40; 95 % CI 0.25–0.66, respectively. Although not significant, more VTE events occurred during winter (p=0.09). No seasonal variations of vitamin D levels were found (p=0.11). In conclusion, in contrast with previous reports our findings suggest that vitamin D is not associated with VTE in the elderly population.

scholarly journals Vitamin D serum levels and peripheral arterial disease among southern Brazilian adults

2020 ◽  
Vol 66 (3) ◽  
pp. 268-274 ◽  
Author(s):  
Simone Bonatto ◽  
Vera Maria Vieira Paniz ◽  
Clandio de Freitas Dutra ◽  
Ruth Liane Henn
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Peripheral Arterial Disease ◽  
Ankle Brachial Index ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Arterial Disease ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Peripheral Arterial

SUMMARY OBJECTIVE To investigate the association between low serum vitamin D levels and peripheral arterial disease (PAD). METHODS A cross-sectional study with a consecutive sample of 133 individuals from Caxias do Sul, Brasil. We considered PAD patients those with an ankle-brachial index (ABI) ≤ 0.90 or with arterial revascularization. Vitamin D serum level was categorized as sufficient (≥30 ng/mL), insufficient (>20 to 29 ng/mL), and deficient (<20 ng/mL). Prevalence ratios (RP) were calculated through Poisson regression. RESULTS The prevalence of PAD was 50.7% (95% CI 42-59). After adjustment for potential PAD risk factors, RP were 1.08 (95% CI 0.66-1.76) for insufficient serum level and 1.57 (95% CI 0.96-2.57) for deficient vitamin D serum level; (p for trend = 0.020). CONCLUSION Vitamin D serum levels showed an inverse and significant dose-response relationship with PAD.

scholarly journals Evaluation of Serum Level of Vitamin D in Patients with Female Pattern Hair Loss Thesis

2021 ◽  
pp. 157-162
Author(s):  
Manar Elsayed Taha Sadoma ◽  
Ghada Fawzy Rezk Hassan ◽  
Manal Mohamed ALI Elbatsh ◽  
Zeinab AbdElsamd Ibrahim
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Hair Loss ◽  
Vitamin D3 ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Common Cause ◽  
Female Pattern Hair Loss ◽  
Vitamin D Levels ◽  
25 Hydroxy Vitamin D

Background: Female pattern hair loss (FPHL) is the most common cause of alopecia in women, characterized by diffuse non-scarring hair loss in frontal, central, and parietal areas of the scalp. Vitamin D is a factor that has recently been considered in dealing with these patients.  Objective: The aim of this work was to evaluate the serum level of 25 hydroxy vitamin D in patients with FPHL to elucidate its possible role in the pathogenesis of the disease. Methods: This study included 45 patients with female pattern hair loss; Evaluation of vitamin D level by Elisa was done for both control and patients. Results: Regarding vitamin D levels, mean ± SD. 18.0 ± 11.97. Conclusion: This study indicated the correlation between FPHL and decreased serum levels of Vitamin D3. It is recommended to evaluate serum Vitamin D3 levels as well as other hormone assays in these patients.

scholarly journals Prevalence of vitamin D insufficiency in Qatar: a systematic review

2012 ◽  
Vol 1 (3) ◽  
pp. 36 ◽  
Author(s):  
Alaa Badawi ◽  
Paul Arora ◽  
Eman Sadoun ◽  
Al-Anoud Al-Thani ◽  
Mohamed H. Al Thani
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Sample Size ◽  
Serum Vitamin ◽  
Weighted Average ◽  
Serum Levels ◽  
Vitamin D Insufficiency ◽  
Vitamin D Status ◽  
Serum Vitamin D ◽  
Vitamin D Levels

Qatar has a high burden of chronic diseases including obesity, cardiovascular disease and type 2 diabetes mellitus. Low serum vitamin D levels have been implicated in the development and progression of a range of these chronic conditions. The prevalence of vitamin D insufficiency or deficiency in the general population of Qatar has still not been investigated. The aim of this study was to carry out a systematic review of published studies documenting the prevalence of vitamin D insufficiency or deficiency in the Qatari population. A search strategy was developed for online databases (PubMed, Ovid MEDLINE, Embase and Embase Classic) between 1980 to the last week of August 2012, and bibliographies of the included studies were further searched for additional reports. Search terms used were QATAR and VITAMIN D. Studies reporting the serum levels of vitamin D in several Qatari sub-populations were identified. Weighted-average vitamin D serum levels and prevalence of low vitamin D status (&lt;75 nmol/L) were calculated. Subgroup analysis was carried out by age. The quality of each study was evaluated according to four criteria: national representativeness, representation of males and females, the sample size, and the sampling protocol. A total of 16 relevant publications were identified, and 8 of these (reporting from 7 unique studies) met our inclusion and exclusion criteria with a total number of 1,699 Qatari subjects. The pooled sample size weighted-average vitamin D concentration (±SD) was 45.3±14.3 nmol/L (95% CI: 44.6-46.0; range 29.2-66.9 nmol/L). The weighted-average prevalence of low vitamin D status was 90.4% (95% CI: 90.1-91.0; range 83%-91%). Age was inversely correlated with vitamin D levels and directly with its insufficiency/deficiency prevalence. There have only been a few studies on the prevalence of low vitamin D in Qatar a very high prevalence of vitamin D insufficiency/deficiency in Qatar that increases with age has been suggested. The present report underlines the need to develop a nationally representative study to further evaluate vitamin D status in Qatar. Given the growing evidence of the role of vitamin D in chronic disease, this study could help develop public health strategies for disease prevention in Qatar.

scholarly journals TREM-2 Receptor Expression Increases with 25(OH)D Vitamin Serum Levels in Patients with Pulmonary Sarcoidosis

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Maria Bucova ◽  
Magda Suchankova ◽  
Elena Tibenska ◽  
Eva Tedlova ◽  
Juraj Demian ◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Serum Levels ◽  
Pulmonary Sarcoidosis ◽  
Normal Serum ◽  
Receptor Expression ◽  
Normal Range ◽  
Inactive Form ◽  
Vitamin D Levels ◽  
Low Levels

TREM-1 and TREM-2 molecules are members of the TREM transmembrane glycoproteins. In our previous study we identified increased expressions of TREM-1 and TREM-2 receptors in pulmonary sarcoidosis (PS). Only a few studies concerning the association between vitamin D and TREM receptor expression can be found. The aim of our current study was to determine the association between the levels of an inactive form of 25(OH)D vitamin and TREM-1 and TREM-2 receptor expressions. We have detected low levels of 25(OH)D vitamin in 79% of PS patients. Only 21% of patients had normal serum level of 25(OH)D vitamin with values clustered within the low-normal range. The most striking findings were the increased TREM-2 expressions on myeloid cells surfaces in BALF of PS patients with normal 25(OH)D vitamin serum levels compared with those with its decreased levels. The total number of TREM-2 positive cells was 5.7 times higher and the percentage of TREM-2 positive cells was also significantly increased in BALF of PS patients with normal compared to PS patients with low 25(OH)D vitamin serum levels. A significant correlation between total TREM-2 expression and vitamin D levels has been detected too. However, we have not detected similar differences in TREM-1expression and 25(OH)D vitamin serum levels.

scholarly journals Serum 25-hydroxy Vitamin D levels in patients with Chronic Obstructive Pulmonary Disease exacerbation: Short Communication

2021 ◽  
pp. 408-413
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Vitamin D ◽  
Serum Level ◽  
Vitamin D Deficiency ◽  
Serum Levels ◽  
Chronic Obstructive ◽  
Copd Exacerbation ◽  
Disease Exacerbation ◽  
Obstructive Pulmonary Disease ◽  
Vitamin D Levels

Regarding immune-regulatory roles of vitamin D as well as its effect on Chronic Obstructive Pulmonary Disease (COPD), the present study aimed to evaluate serum vitamin D levels in patients with COPD exacerbation. The study population included 70 patients with COPD exacerbation who were hospitalized in the general ward of an affiliated hospital with Birjand University of Medical Sciences, Birjand, Iran. Blood samples were taken from the patients and transmitted to the laboratory for vitamin D serum levels assessment after serum separation. The patients were staged according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria. Spirometry was performed during the disease exacerbation and one month after discharge. The Mean±SD age of the studied patients was 65.44±13.3 years. Out of the70 studied patients in this study, 33 (47.1%), 28 (40%), and 9 (11.7%) cases had vitamin D deficiency, insufficient levels of vitamin D, and normal serum levels of vitamin D, respectively. Mean±SD vitamin D serum level in the studied patients was obtained at 14.1±1.98 ng/dl. No significant difference was observed between vitamin D serum levels in different stages in terms of severity of COPD (P=0.26). Based on the obtained results, most patients with COPD exacerbation suffer from vitamin D deficiency. Therefore, the measurement of vitamin D serum level and prescription of vitamin D supplements seem to be a necessary measure for these patients

scholarly journals Vitamin D Deficiency in Mice Impairs Colonic Antibacterial Activity and Predisposes to Colitis

Endocrinology ◽  
2010 ◽  
Vol 151 (6) ◽  
pp. 2423-2432 ◽  
Author(s):  
Venu Lagishetty ◽  
Alexander V. Misharin ◽  
Nancy Q. Liu ◽  
Thomas S. Lisse ◽  
Rene F. Chun ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Levels ◽  
Enteric Bacteria ◽  
Sodium Sulphate ◽  
Antimicrobial Protein ◽  
Vitamin D Status ◽  
Colon Tissue ◽  
Vitamin D Levels ◽  
Deficient Mice

Vitamin D insufficiency is a global health issue. Although classically associated with rickets, low vitamin D levels have also been linked to aberrant immune function and associated health problems such as inflammatory bowel disease (IBD). To test the hypothesis that impaired vitamin D status predisposes to IBD, 8-wk-old C57BL/6 mice were raised from weaning on vitamin D-deficient or vitamin D-sufficient diets and then treated with dextran sodium sulphate (DSS) to induce colitis. Vitamin D-deficient mice showed decreased serum levels of precursor 25-hydroxyvitamin D3 (2.5 ± 0.1 vs. 24.4 ± 1.8 ng/ml) and active 1,25-dihydroxyvitamin D3 (28.8 ± 3.1 vs. 45.6 ± 4.2 pg/ml), greater DSS-induced weight loss (9 vs. 5%), increased colitis (4.71 ± 0.85 vs. 1.57 ± 0.18), and splenomegaly relative to mice on vitamin D-sufficient chow. DNA array analysis of colon tissue (n = 4 mice) identified 27 genes consistently (P &lt; 0.05) up-regulated or down-regulated more than 2-fold in vitamin D-deficient vs. vitamin D-sufficient mice, in the absence of DSS-induced colitis. This included angiogenin-4, an antimicrobial protein involved in host containment of enteric bacteria. Immunohistochemistry confirmed that colonic angiogenin-4 protein was significantly decreased in vitamin D-deficient mice even in the absence of colitis. Moreover, the same animals showed elevated levels (50-fold) of bacteria in colonic tissue. These data show for the first time that simple vitamin D deficiency predisposes mice to colitis via dysregulated colonic antimicrobial activity and impaired homeostasis of enteric bacteria. This may be a pivotal mechanism linking vitamin D status with IBD in humans.

Vitamin D and breast cancer

2014 ◽  
Vol 155 (28) ◽  
pp. 1091-1096 ◽  
Author(s):  
Tamás Nagykálnai ◽  
László Landherr ◽  
András Csaba Nagy
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Tumor Suppressor Genes ◽  
Active Form ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Vitamin D Supplementation ◽  
Scientific Publications ◽  
Serum Vitamin D ◽  
Vitamin D Levels

The active form of vitamin D, in conjunction with his own receptor, affect a multitude of biological processes in the cell (inter alia it influences the expression of oncogenes and tumor suppressor genes). There is an increasing volume of scientific publications examining the relationships between serum vitamin D levels, vitamin D supplementation and malignant diseases. Some articles suggest inverse relationship between the low serum levels of vitamin D and the breast cancer risk and mortality, whilst other publications do not support this view. Thus the present opinion is conflicted. Vitamin D can exert a beneficial influence on the symptoms and outcomes of a large number of ailments, but its role in affecting cancer is still not completely clear. Orv. Hetil., 2014, 155(28), 1091–1096.

scholarly journals Adequate Vitamin D Intake but Low Serum Levels in Pediatric Asthma Patients: A Pilot Study, Alberta Children’s Hospital

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Sarah Howe McKenna ◽  
Tanis R. Fenton ◽  
Mary Noseworthy ◽  
Mark Anselmo
Keyword(s):  
Vitamin D ◽  
Pediatric Asthma ◽  
Serum Levels ◽  
High Dose ◽  
Healthy Children ◽  
Vitamin D Status ◽  
Vitamin D Intake ◽  
Vitamin D Levels ◽  
Asthma Patients ◽  
25 Oh Vitamin D

Background. We assessed vitamin D intakes and serum 25(OH) vitamin D levels in pediatric asthma patients on moderate-to-high dose inhaled steroids and compared them to published findings of healthy children in our city.Methods. Parents and/or patients were interviewed to estimate the children’s vitamin D intakes from foods and supplements (using an adapted validated food frequency questionnaire) and asthma duration and management. Vitamin D status: serum 25-hyroxy vitamin D (25(OH)D) was obtained from the medical records.Results. Vitamin D intakes from food and supplements of the asthma patients (n=20, 742 ± 185 IU/day) were significantly higher compared to healthy Canadian children (n=1442, 229 ± 121 IU/day). Despite higher vitamin D intakes, the children had nonsignificantly lower serum 25(OH) vitamin D levels compared to the comparison group. Serum 25(OH)D levels increased by 3.6 nmol/L with each 100 IU of vitamin D intake (95% Confidence interval = 2.0–4.0,R2= 0.931, andp=0.001).Conclusion. Since adequate vitamin D status in asthma patients is necessary to support bone mineral accretion, it is important to achieve adequate vitamin D status by checking serum 25(OH)D status and supplement accordingly.

Sign in / Sign up

Export Citation Format

Share Document