scholarly journals BMI and Waist Circumference Have Positive Correlation With Mitochondrial DNA Copy Number in Young Adult Male

2018 ◽  
Vol 8 (1) ◽  
pp. 1-6
Author(s):  
Liong Boy Kurniawan ◽  
Uleng Bahrun ◽  
Mochammad Hatta ◽  
Mansyur Arif

Background:Abdominal obesity is associated with metabolic and cardiovascular diseases. Mitochondrial dysfunction is often related to metabolic disorder commonly found in abdominal obesity. Mitochondrial DNA (mtDNA) copy number is a biomarker which can be used to reflect the activity of mitochondria. Abdominal obesity is more commonly found in males compared to females and the incidence is growing in young adult male, therefore we investigated the relationship of mtDNA copy number and anthropometric and metabolic biomarkers in young adult male.Methods:A total of 25 healthy young adult males of age 19 to 24 years old were recruited in the study. Metabolic biomarkers were evaluated along with body mass index, waist circumference and total body fat, visceral fat by bioelectrical impedance analysis. mtDNA copy number was measured in peripheral blood leukocytes by using real-time polymerase chain reaction method.Results:After adjusting for ages, mtDNA copy number correlated with body mass index (r= 0.45,P= 0.03) and waist circumference (r= 0.43,P= 0.04) but had no significant correlation with fasting plasma glucose, insulin, HOMA-IR, testosterone, total body fat and visceral fat.Conclusion:mtDNA copy number has a positive correlation with BMI and waist circumference. Even though it is still controversial over other studies, further studies are needed to explain the causality and significance of our findings.

2021 ◽  
Vol 22 ◽  
pp. 100975
Author(s):  
Ellen Duncan ◽  
Suneet Bhansali ◽  
Ee Tein Tay

Author(s):  
Asma Alonazi ◽  
Shahnaz Hasan ◽  
Shahnawaz Anwer ◽  
Azfar Jamal ◽  
Suhel Parvez ◽  
...  

This study compares the effects of electromyographic-biofeedback (EMG-BF)-guided isometric quadriceps strengthening with patellar taping and isometric exercise alone in patellofemoral pain syndrome (PFPS) among young adult male athletes. Sixty young adult male athletes with PFPS participated in the study. Participants were randomly divided into two groups: (1) EMG-BF-guided isometric exercise training with patellar taping (experimental group, n = 30), and (2) sham EMG-BF training with an isometric exercise program (control group, n = 30). Participants conducted their respective exercise programs for five days per week across four weeks. Study outcomes were pain (measured by the visual analog scale), functional disability (measured by the Kujala Anterior Knee Pain scale), and quadriceps strength (measured by an ISOMOVE dynamometer). Measurements were taken at baseline, Week 2, Week 4, and during a follow-up at Week 6. The experimental group demonstrated significantly lower VAS score at Weeks 2 and 4 compared to that of the control group (p = 0.008 and 0.0005, respectively). The score remained significantly lower at the Week 6 follow-up compared to the control group (p = 0.0005). There were no differences in knee function at Weeks 2 and 4 between the two groups (p = 0.086 and 0.171, respectively); however, the experimental group showed significantly better knee function at Week 6 compared to the control group (p = 0.002). There were no differences in quadriceps strength at Week 2 between the two groups (p = 0.259); however, the experimental group demonstrated significantly higher quadriceps strength at Weeks 4 and 6 compared to the control group (p = 0.0008). Four weeks of EMG-BF supplementation training with patellar taping demonstrated significant improvements in pain intensity, functional disability, and quadriceps muscle strength in young adult male athletes with PFPS.


Medicine ◽  
2017 ◽  
Vol 96 (39) ◽  
pp. e8126 ◽  
Author(s):  
Yiu-Hua Cheng ◽  
Yu-Chung Tsao ◽  
I-Shiang Tzeng ◽  
Hai-Hua Chuang ◽  
Wen-Cheng Li ◽  
...  

1966 ◽  
Vol 9 (2) ◽  
pp. 194-207 ◽  
Author(s):  
Eugene B. Cooper

Interrelationships among client progress in stuttering therapy, the nature of the affect interchange between client and clinician, and certain personality characteristics of both client and clinician were studied. Sixteen young adult male stutterers and their 11 graduate student clinicians served as subjects. Results support observations that the clinicians' and clients' personalities are significant variables in the stuttering therapy situation, support observations that important similarities exist between stuttering therapy and psychotherapy, and suggest that it is more accurate to note stages in the therapeutic relationship, rather than to characterize the relationship as if it were the same throughout therapy.


2013 ◽  
Vol 229 (2) ◽  
pp. 227-234 ◽  
Author(s):  
Emily E. Roguski ◽  
Hao Chen ◽  
Burt M. Sharp ◽  
Shannon G. Matta

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