Future trends in carbon nanotubes: Process towards a viable biomedical solution

2021 ◽  
Vol 06 ◽  
Author(s):  
Raja Murugesan ◽  
Sureshkumar Raman ◽  
Arun Radhakrishnan
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Biomedical Applications ◽  
Scale Up ◽  
Diagnostic Techniques ◽  
Nano Composite ◽  
Methods Of Synthesis ◽  
In Trans ◽  
Functionalization Of Carbon Nanotubes

Background: Recently, Nanomaterials based nano-composite materials play the role of various field. Especially, Carbon nanotube based materials are involved in the bio-medical applications.Since, their exclusive and exciting property, researchers worldwide have extensively involved in trans-modulating the carbon nanotubes into a viable medico-friendly system. Objective: These active researches paved the path towards targeted drug delivery, diagnostic techniques, and bio-analytical applications. Despite these exciting properties, which accomplish the probable for biomedical applications, they hold Biosafety issues. Methods: This broad-spectrum review has discussed different aspects of carbon nanotubes and carbon nanotube-based systems related to biomedical applications. Results: Adding to this, a short chronological description of these tiny yet powerful particles given, followed by a discussion regarding their types, properties, methods of synthesis, scale-up, purification techniques and characterization aspects of carbon nanotubes. Conclusion: In the later part, the functionalization of carbon nanotubes was reviewed in detail, which is important to make them biocompatible and stable in biological systems and render them a great property of loading various biomolecules diagnostic and therapeutic moieties. Lastly, an inclusive description of the potential biomedical applications has been given followed by insights into the future.

Role of polymers in the design of 3D carbon nanotube-based scaffolds for biomedical applications

2014 ◽  
Vol 39 (7) ◽  
pp. 1448-1471 ◽  
Author(s):  
María C. Serrano ◽  
María C. Gutiérrez ◽  
Francisco del Monte
Keyword(s):  
Carbon Nanotube ◽  
Biomedical Applications

Large-Scale Assembly of Carbon Nanotubes

2004 ◽  
Author(s):  
T. El-Aguizy ◽  
Sang-Gook Kim
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Large Scale ◽  
Small Scale ◽  
Manufacturing Processes ◽  
Micro Scale ◽  
Multi Scale ◽  
Novel Method ◽  
Functionalization Of Carbon Nanotubes

The scale decomposition of a multi-scale system into small-scale order domains will reduce the complexity of the system and will subsequently ensure a success in nanomanufacturing. A novel method of assembling individual carbon nanotube has been developed based on the concept of scale decomposition. Current technologies for organized growth of carbon nanotubes are limited to very small-scale order. The nanopelleting concept is to overcome this limitation by embedding carbon nanotubes into micro-scale pellets that enable large-scale assembly as required. Manufacturing processes have been developed to produce nanopellets, which are then transplanted to locations where the functionalization of carbon nanotubes are required.

Non-covalent double functionalization of carbon nanotubes with a NADH oxidation Ru(ii)-based molecular catalyst and a NAD-dependent glucose dehydrogenase

2014 ◽  
Vol 50 (79) ◽  
pp. 11731-11734 ◽  
Author(s):  
B. Reuillard ◽  
A. Le Goff ◽  
S. Cosnier
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Ruthenium Complex ◽  
Glucose Dehydrogenase ◽  
Nadh Oxidation ◽  
Stacking Interactions ◽  
Molecular Catalyst ◽  
Π Stacking ◽  
Functionalization Of Carbon Nanotubes

Functionalization of carbon nanotube electrodes by glucose dehydrogenase and a ruthenium complex as a NADH electrocatalyst via π-stacking interactions.

scholarly journals Investigation of cytotoxic activity and dissolution improvement of Teniposide by incorporation into acid treated carbon nanotube and dispersed by hydrophilic polymer

2019 ◽  
Vol 28 (1) ◽  
pp. 91-100
Author(s):  
Raid Mohamed Al abood ◽  
Mowafaq M. Ghareeb ◽  
Alaa A. Abdulrasool
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Cytotoxic Activity ◽  
Quantitative Estimation ◽  
Visual Observation ◽  
Pharmaceutical Properties ◽  
Treated Carbon ◽  
Functionalization Of Carbon Nanotubes ◽  
Walled Carbon Nanotubes ◽  
Strong Acids

Single Walled Carbon nanotubes (SWCNTs), as nano-needle structures, are good candidates as nanocarrier delivery systems that carry drug to the site of action. They are good due to their unique pharmaceutical properties. Teniposide is an anticancer drug, which is widely used, but it has a problem of low solubility. In this study, to improve the properties of carbon nanotubes, pre-functionalization of carbon nanotubes via carboxylation with strong acids has been performed and then functionalized through attaching them to the polymer and copolymer. Concurrently, a proper polymer-copolymer combination has been selected by the UV-Visible spectrometer at 880nm. It is selected based on the qualitative dispersibility analysis, the visual observation of homogeneity, and separation tendency after centrifugation while quantitative estimation. The best formula is further studied utilizing FTIR, SEM, TEM, the solubility of Teniposide, and cytotoxicity through cell lines analysis.             The results show that the best dispersibility obtained in the formula that used PVA as polymer and PEO as copolymer at a ratio of 1:1. The solubility of incorporated Teniposide in the selected formula is increased by 11.5 fold and the cell line study shows significant improvement in cytotoxic activity of Teniposide. Accordingly, it can be concluded that the acid treated carbon nanotube and linked by polymer improve the pharmaceutical properties of the carrier and actively increase the potency of drug.

scholarly journals Dark-Field Hyperspectral Microscopy for Carbon Nanotubes Bioimaging

2021 ◽  
Vol 11 (24) ◽  
pp. 12132
Author(s):  
Ilnur Ishmukhametov ◽  
Rawil Fakhrullin
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Optical Microscopy ◽  
Biomedical Applications ◽  
Dark Field ◽  
Chemical Identification ◽  
Nanoscale Particles ◽  
Spectral Identification ◽  
Tyndall Effect ◽  
Dark Field Microscopy

Carbon nanotubes have emerged as a versatile and ubiquitous nanomaterial, finding applications in industry and biomedicine. As a result, biosafety concerns that stimulated the research focused on evaluation of carbon nanotube toxicity. In addition, biomedical applications of carbon nanotubes require their imaging and identification in biological specimens. Among other methods, dark-field microscopy has become a potent tool to visualise and identify carbon nanotubes in cells, tissues, and organisms. Based on the Tyndall effect, dark-field optical microscopy at higher magnification is capable of imaging nanoscale particles in live objects. If reinforced with spectral identification, this technology can be utilised for chemical identification and mapping of carbon nanotubes. In this article we overview the recent advances in dark-field/hyperspectral microscopy for the bioimaging of carbon nanotubes.

Synthesis and Applications of Hydrogels in Cancer Therapy

2020 ◽  
Vol 20 (12) ◽  
pp. 1431-1446
Author(s):  
Anchal Singhal ◽  
Niharika Sinha ◽  
Pratibha Kumari ◽  
Manoushikha Purkayastha
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Cancer Therapy ◽  
Mechanical Strength ◽  
Biomedical Applications ◽  
Three Dimensional ◽  
Polymer Chains ◽  
Human Tissues ◽  
Methods Of Synthesis

: Hydrogels are water-insoluble, hydrophilic, cross-linked, three-dimensional networks of polymer chains having the ability to swell and absorb water but do not dissolve in it, that comprise the major difference between gels and hydrogels. The mechanical strength, physical integrity and solubility are offered by the crosslinks. The different applications of hydrogels can be derived based on the methods of their synthesis, response to different stimuli, and their different kinds. Hydrogels are highly biocompatible and have properties similar to human tissues that make it suitable to be used in various biomedical applications, including drug delivery and tissue engineering. The role of hydrogels in cancer therapy is highly emerging in recent years. In the present review, we highlighted different methods of synthesis of hydrogels and their classification based on different parameters. Distinctive applications of hydrogels in the treatment of cancer are also discussed.

Micro-Raman study of the role of sterilization on carbon nanotubes for biomedical applications

Nanomedicine ◽  
2010 ◽  
Vol 5 (2) ◽  
pp. 209-215 ◽  
Author(s):  
Stefano Bellucci ◽  
Massimo Chiaretti ◽  
Pasquale Onorato ◽  
Francesco Rossella ◽  
Marco Simone Grandi ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Biomedical Applications ◽  
Raman Study

Carbon nanotubes in cancer therapy: a more precise look at the role of carbon nanotube–polymer interactions

2013 ◽  
Vol 42 (12) ◽  
pp. 5231 ◽  
Author(s):  
Mohsen Adeli ◽  
Rouhollah Soleyman ◽  
Zahra Beiranvand ◽  
Fahimeh Madani
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Cancer Therapy ◽  
Polymer Interactions

ROLE OF DEFECTS IN CARBON NANOTUBE CIRCUITS

2002 ◽  
Vol 01 (03n04) ◽  
pp. 247-254
Author(s):  
A. T. JOHNSON ◽  
M. FREITAG ◽  
M. RADOSAVLJEVIC ◽  
S. V. KALININ ◽  
D. A. BONNELL
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Quantitative Agreement ◽  
Single Wall Carbon Nanotubes ◽  
Metallic State ◽  
Scanning Gate Microscopy ◽  
Electrostatic Doping ◽  
Scanning Gate ◽  
The Impact

We summarize recent results on the impact of defects on the electronic properties of single-wall carbon nanotubes. We probe the influence of defects on electron transport in CNFETs by combined scanning gate microscopy (SGM) and scanning impedance microscopy (SIM). Depletion surface potential of individual defects is quantified from the SGM-imaged defect radius as a function of tip bias voltage. This provides a measure of the Fermi level at the defect with zero tip voltage. In the "off" state, transport is first dominated by barriers at depleted defects. It becomes diffusive as the CNFET is turned on, and finally is quasi-ballistic in the regime of "degenerate electrostatic doping". Metallic nanotubes with good contacts show a metal-to-insulator crossover as the gate voltage is varied. In the metallic state we see quantitative agreement with the "twiston" scattering picture.

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