Antifungal activity of plant extracts against dandruff causing organism Malassezia furfur

In the present study, an attempt was made to know the activity of different plant extracts against the dandruff causing organism Malassezia furfur. Various parts of twelve different plants were collected and their crude as well as powered extracts were used for the activity studies. The evaluation was done using cup plate method. Sensitivity of the organism to marketed antidandruff shampoos was also studied. Of all the extracts, antifungal activity was shown by lemon, amla, shikakai, henna (decreasing order of activity). These results were compared with the antifungal activity of three branded shampoos. On comparison, it is inferred that plant extracts showed promising activity against Malassezia furfur when compared with the marketed antidandruff shampoos.

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Antifungal activity of phytochemical compounds of extracts from Mexican semi-desert plants against Fusarium oxysporum from tomato by microdilution in plate method

Nova Scientia ◽

10.21640/ns.v12i25.2345 ◽

2020 ◽

Vol 12 (25) ◽

Author(s):

Marco Antonio Tucuch-Perez ◽

Roberto Arredondo-Valdes ◽

Francisco Daniel Hernandez-Castillo

Keyword(s):

Antifungal Activity ◽

Fusarium Oxysporum ◽

Plant Extracts ◽

Inhibitory Concentration ◽

Larrea Tridentata ◽

Aqueous Extracts ◽

Desert Plants ◽

Plate Method ◽

Crude Extracts ◽

Phytochemical Compounds

Introduction: In several regions of the world, Fusarium oxysporum causes losses on tomato crops; for control it, chemical fungicides are used. Nevertheless, these fungicides causing environmental and resistance problems; therefore, ecological alternatives as plant extracts have been developed. Due to the aim of this work, identify phytochemicals present in ethanolic and aqueous extracts from Agave lechuguilla qualitatively, Carya illinoinensis, Jatropha dioica, Larrea tridentata, and Lippia graveolens and determine their antifungal activity against F. oxysporum.Method: The plants collected from the northeast of Mexico; crudes and concentrated plant extracts obtained; the inhibition percentage and inhibitory concentration to 50 % (IC50) of F. oxysporum for each plant extract were determinate trough microdilution in the plate methodResults: The essential phytochemicals were flavonoids, saponins, tannins, and quinones. The antifungal activity showed at 1000 mg/L inhibition around 40 to 60% by aqueous crude extracts from leaves of L. graveolens and concentrated aqueous extracts from the stem of L. graveolens, respectively. The ethanolic extracts presented 100 % of inhibition for crude extracts of husk from C. illinoinensis; in leaves and stem from L. graveolens the inhibition started from 250 mg/L; for resuspended extracts, the inhibition started from 125 mg/L with L. graveolens stem and leaves; and finally in roots of A. lechuguilla and leaves from L. graveolens the inhibition started from to 250 and 500 mg/L respectively. The best IC50 was of 8.02 mg/L from the ethanolic resuspended extract of L. graveolens stem.Conclusion: The ethanolic plant extracts from L. graveolens, A. lechuguilla, and C. illinoinensis, showed 100 % of inhibiting activity against the development of F. oxysporum, representing an alternative for control of F. oxysporum.

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Insignificant antifungal activity of plant extracts on Malassezia furfur

Journal of Pharmaceutical Negative Results ◽

10.4103/0976-9234.177055 ◽

2016 ◽

Vol 7 (1) ◽

pp. 16 ◽

Cited By ~ 2

Author(s):

Sharmila Thirumale ◽

SreelathaGopalakrishnan Lalitha ◽

LakshmeeshaThimappa Ramachandrappa ◽

Soumya Krishnamurthy ◽

Jayashree Basavaraju

Keyword(s):

Antifungal Activity ◽

Plant Extracts ◽

Malassezia Furfur

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Therapeutic efficacy of some extracts of hot pepper fruits (Capsicum annuum) and Sumac seeds (Rhus coriaria) on the growth of some isolated dermatophytes species

International Journal of Medical Sciences ◽

10.32441/ijms.v1i3.102 ◽

2018 ◽

Vol 1 (3) ◽

pp. 52-62

Author(s):

Sara Omran ◽

Abdulghani Alsamarai ◽

Firas Razzzaq

Keyword(s):

Antifungal Activity ◽

Fungal Infection ◽

Aqueous Extract ◽

Plant Extracts ◽

Therapeutic Efficacy ◽

Diffusion Method ◽

Quantitative Detection ◽

Hot Pepper ◽

Alcoholic Extract ◽

Dermatology Clinic

Background: Fungal infections are one of the common skin diseases with difficulty in their treatment approach. The present efficient drugs for fungal infection are limited. Aim: To determine the therapeutic efficacy of plant extracts as alternative antifungal agents. Materials and methods: 100 clinical samples [68 from female and 32 from male] were collected during the period from March to July 2017 from subjects attending Dermatology Clinic in Salah Uldean General Hospital. Fungal infection was diagnosed with using KOH wet preparation. Fungal species identified by using conventional approach. The active ingredients existing in the plant extracts were detected and analyzed through qualitative and quantitative detection technique of chemical compounds using a high performance liquid chromatographic device (HPLC). Agar diffusion method was used to determine antifungal activity of plant extracts. Results: Direct microscopic examination showed that there were (75%) positive samples, while culture shows (67%) positive samples. The isolated dermatophytes belong to Epidermophyoton, Microsporum, and Trichophyton genus. The predominant dermatophytes were T. rubrum (25%) species. The highest frequency of infection was in the age group of 11-20 years. The sensitivity of the tested fungi to the aqueous and alcoholic plant extracts varies. Alcoholic extract of the hot pepper plant was more effective as antifungal than the aqueous extract of the same plant. However, aqueous hot pepper extracts was more effective against T. mentagrophyte than that of alcoholic extract. Additionally, alcoholic Sumac extract shows higher efficacy that aqueous extract. Conclusion: Hot pepper and Sumac extracts show antifungal activity against Microsporum canis, Trichophyton rubrum and T. mentagrophyte.

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Antifungal activity of medicinal plant extracts for potential management of Fusarium pathogens

Research on Crops ◽

10.31830/2348-7542.2019.058 ◽

2019 ◽

Vol 20 (2) ◽

Keyword(s):

Antifungal Activity ◽

Medicinal Plant ◽

Plant Extracts ◽

Medicinal Plant Extracts ◽

Fusarium Pathogens

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Protective Antifungal Activity of Plantago major Extract Against the Phytopathogenic Fungi Phytophthora cinnamomi, Diplodia corticola and Colletotrichum Species

Proceedings ◽

10.3390/foods_2020-07678 ◽

2020 ◽

Vol 70 (1) ◽

pp. 94

Author(s):

Cláudia Ferreira ◽

Rui Oliveira

Keyword(s):

Antifungal Activity ◽

Secondary Metabolites ◽

Plant Extracts ◽

Phytophthora Cinnamomi ◽

Fungal Infections ◽

Petri Dish ◽

Phytopathogenic Fungi ◽

Colletotrichum Acutatum ◽

Lower Probability ◽

Plantago Major

Synthetic fungicides for crops protection raise environmental and human concerns due to accumulation in edible vegetables, showing significant toxicity to humans, and in soil, groundwater and rivers, affecting ecological balance. In addition, they are prone to the development of resistant strains because of the single target-based mechanism of action. Plant extracts provide attractive alternatives, as they constitute a rich source of biodegradable secondary metabolites, such as phenols, flavonoids and saponins, which have multiple modes of antifungal action and a lower probability of the development of resistant fungi. This work has the objective of identifying plant extracts with antifungal activity, aiming to contribute to food safety and sustainable agricultural practices. We selected a saponin-containing plant, Plantago major, and extracted secondary metabolites with 50% (v/v) ethanol, dried by evaporation, and dissolved in water. For antifungal activity, the phytopathogenic fungi Colletotrichum acutatum, Colletotrichum gloeosporioides, Colletotrichum godetiae, Colletotrichum nymphaeae, Diplodia corticola and Phytophthora cinnamomi were selected because they affect fruits and vegetables, such as strawberry, almond, apple, avocado, blueberry and chestnut trees. The aqueous extract was incorporated into PDA medium at different concentrations and mycelial discs were placed in the center of each Petri dish. Growth was measured as the radial mycelial growth at 3, 6, and 9 days incubation at 25 °C in the dark. The maximum growth inhibition (32.2%) was obtained against P. cinnamomi with 2000 µg/mL extract followed by C. gloeosporioides (25.7%) on the sixth day and by C. godetiae and C. nymphaeae (21.1%) on the ninth day. Results show that P. major presents antifungal activity in all phytopathogenic fungi tested and the extract can be used to protect important crops, by inhibiting the development of fungal infections and promoting food security and a sustainable agriculture.

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