Pharmaceutico analytical study of Shodhita Shilajatu

Background: Shilajatu or Adrija is one of the Maharasa, which is considered as a wonderful medicine in Ayurveda. It is named as it comes out of the stones heated by the sun in summer in the form of thick blackish exudation having many shades. Since it contain stone, mud, wood, sand and various physical and metallic impurities, Shodhana (Purification) of Shilajatu is a mandatory procedure. It has been used as a prime ingredient in many formulations mainly for Prameha, Sotha, Pandu Roga, Kshaya, Swasa, Pliha Vrudhi, Jwara, Agnimandya, Apasmara, etc. Objectives: Shodhana of Ashudha Shilajatu and Physico chemical analysis of Shodhita Shilajatu. Materials and Methods: Bhringaraja Swarasa for Shodhana of Shilajatu. Results:It took 8 days for completion of Shilajatu Shodhana. XRD Analysis report indicates that the sample Shilajatu was Amorphous material. Conclusion: Total yield of Shodhita Shilajatu was 99.6%. The Sample of Shilajatu was found to be Amorphous material in XRD Analysis hence crystal structure was not identified.

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PHYSICO-CHEMICAL ANALYSIS OF SHADGUNA KAJJALI AND SHADGUNA BALIJARITA RASASINDURA)

International Journal of Research in AYUSH and Pharmaceutical Sciences ◽

10.47070/ijraps.v4i8.93 ◽

2020 ◽

pp. 440-446

Author(s):

Sorab Gaind ◽

Pradeep Agnihotri

Keyword(s):

Crystal Structure ◽

Chemical Analysis ◽

Analytical Study ◽

Total Mercury ◽

Hexagonal Crystal Structure ◽

Hexagonal Crystal ◽

Standard Drug ◽

Therapeutic Purpose ◽

Drug Quality ◽

Physico Chemical

Analytical study of any drug is essential to standardize it. Analytical study is carried out to check drug quality. For this purpose some analytical tests are performed and their results are compared with standard parameters. The drug fulfilling these criteria can be taken as standard drug and can be used for therapeutic purpose. Percentage of total mercury in Shadguna Kajjali and Shadguna balijarita rasasindur was 40.03%, and 84.17%. Total Sulphur in Shadguna Kajjali and Shadguna balijarita rasasindur was 43.07% and 11.16%. Percentage of free sulfur in Shadguna Kajjali and Shadguna balijarita rasasindur was 22.11%. XRD of Shadguna balijarita Rasasindur were identified as Cinnabar (Hgs) with Hexagonal Crystal Structure having primitive lattice. In this paper Physico-Chemical Analysis of Shadguna Kajjali and Shadguna balijarita rasasindura is done.

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Microscopic and Phytochemical analysis of Desmodium velutinum (Willd) DC and Desmodium gangeticum (L.) DC. Panchanga powder

Research Journal of Pharmacy and Technology ◽

10.52711/0974-360x.2021.00517 ◽

2021 ◽

pp. 2950-2956

Author(s):

Jigyasa Pathak ◽

Aswathi M. P. ◽

B. R. Patel ◽

Harisha C. R. ◽

Shukla Vinay J.

Keyword(s):

Chemical Analysis ◽

Analytical Study ◽

Water Soluble ◽

Wild Edible Plants ◽

Phytochemical Analysis ◽

Edible Plants ◽

Therapeutic Purpose ◽

Whole Plant ◽

Physico Chemical ◽

Collection Practices

Background: Desmodium velutinum (Fabaceae) is one of the wild edible plants used traditionally to treat diarrhoea, haematuria, infertility and also externally used to treat scorpion bites. Though various parts of the plant have been used for therapeutic purpose, panchanga of the plant has not been studied for its Pharmacognostical and phytochemical characteristics in detail, following scientific parameters. Hence in the present study Desmodium velutinum whole plant has been studied for its pharmacognostical and phytochemical characters and compared with commonly used species Desmodium gangeticum. Methods: Whole plant of Desmodim velutinum was collected from Paikmal, Odisha and Desmodium gangeticum was collected from Junagarh, Gujarat in the month of November 2019 following good collection practices and shade dried. Pharmacognostical study and analytical study were performed following standard pharmacopoeial procedures. Results: Whole plant (Panchanga) of former is sweetish and latter is bitter. Powder microscopy of Desmodium gangeticum showed presence of rhomboidal crystals and lignified annular and spiral vessels. Desmodium velutinum showed presence of prismatic crystals and lignified pitted vessels. Physico-chemical analysis showed higher loss on drying in Desmodium gangeticum, and higher water soluble extractive values of Desmodium velutinum. Phytochemical estimation showed the presence of Proteins, tannins, and carbohydrates in both samples. HPTLC study showed similar Rf value 0.82 and 0.94 at 254 and 0.03 and 0.41 at 366nm. Conclusion: Basing upon the analytical and microscopic similarities Desmodium velutinum may be considered as substitute of Desmodium gangeticum

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Analytical evaluation of Mrityunjaya Rasa

Journal of Ayurveda and Integrated Medical Sciences (JAIMS) ◽

10.21760/jaims.v2i06.10926 ◽

2017 ◽

Vol 2 (06) ◽

Author(s):

Abhishek Abhishek ◽

Ashok Kumar BN ◽

Sujatha K. ◽

Sunil Kumar

Keyword(s):

Chemical Analysis ◽

Analytical Study ◽

Water Soluble ◽

Analytical Evaluation ◽

Text Book ◽

Classical Text ◽

Physico Chemical

Introduction: Mrityunjaya Rasa is a herbo–mineral formulation mentioned under Jwara Chikitsa in Rasendra Sara Sangraha along with different Anupanas. It is having ingredients like Shudha Hingula, Shudha Gandhaka, Shudha Vatsanabha, Shudha Tankana, Pippali and Maricha which show significant result on various types of fever. Aim: To prepare Mrityunjaya Rasa as per guidelines given in classical text book Rasendra Sara Sangraha and to validate physico-chemical analysis of the sample. Methods: The preparation of Mrityunjaya Rasa was carried out at practical hall, Department of Rasashastra and Bhaishajya Kalpana, Shri Dharmasthala Manjunatheshwara College of Ayurveda, Kuthpady, Udupi, Karnataka. It was subjected to analysis on parameters like organoleptic characters, loss on drying, total ash, acid insoluble ash, water soluble ash, pH, alcohol soluble extractive value, and water soluble extractive value. Results: The results of Analytical study showed specific characteristics which are in accordance with the properties of Mrityunjaya Rasa. Conclusion: The study showed significant results, which proves quality of the drugs and efficacy.

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Pharmaceutico-analytical study of Mayurpiccha Bhasma - An Ayurvedic preparation

Journal of Ayurveda and Integrated Medical Sciences (JAIMS) ◽

10.21760/jaims.5.6.16 ◽

2020 ◽

Vol 5 (06) ◽

pp. 116-119

Author(s):

Gangaprasad Asore ◽

Baban Rathod ◽

Dipalee Thakur

Keyword(s):

Chemical Analysis ◽

Moisture Content ◽

Analytical Study ◽

Respiratory Illness ◽

Chemical Components ◽

Physico Chemical

Background: Mayurpiccha Bhasma is a classical Ayurvedic kalpa prepare from peacock feathers, which is commonly used for treatment of Vomiting, Hiccups, Respiratory illness etc. Method of preparation of Mayurpiccha Bhasma is mentioned in Siddhayog sangraha and Bhaishyajya Samhita. Material and Methods: Mayurpiccha Bhasma was prepared by procedure mentioned in Siddhayog sangraha i.e. Peacock feathers are burn on ghee flame and finished product was subjected to various Physico-chemical analysis like Moisture content, Ash value, Chemical components etc. Observations: Observations were noted while testing of finish product. Result and Conclusion: Various observations and reports of tests were noted.

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A PHARMACEUTICO ANALYTICAL STUDY OF TILANALA KSHARASUTRA

November 2020 - International Ayurvedic Medical Journal ◽

10.46607/iamj1408102020 ◽

2020 ◽

Vol 8 (10) ◽

pp. 4656-4661

Author(s):

Radhakrishna Reddy D ◽

Ravi R Chavan ◽

Shankara gowda

Keyword(s):

Clinical Practice ◽

Chemical Analysis ◽

Analytical Study ◽

Uv Light ◽

Operative Procedure ◽

Global Level ◽

Fistula In Ano ◽

Pathological Conditions ◽

Physico Chemical ◽

Glass Tubes

Kshara kalpana (Alkali preparations) is an alkaline herbo-mineral formulation widely used in Ayurvedic Pharmaceutico-therapeutics. Since Ksharasutra has been used widely in Ayurvedic clinical practice spe-cially in Ano rectal pathological conditions. Though Apamarga is most widely used seasonal plant for the preparation of Ksharasutra which is the standard one, the drugs used for the preparation of such standard Kalpana need not to be limited to certain drugs hence in the present study Tilanala has been selected. Aim and objective: The main aim of the study was preparation of Tilanala Ksharasutra as per the classics and physico chemical analysis of Tilanala Ksharasutra. Materials and Methods: Tilanala Ksharasutra was prepared by 11 coatings of Snuhi Ksheera, 7 coatings of Tilanala Kshara, 3 coatings of Haridra Churna and which were kept under UV light for the purpose of sterilization later it was stored in airtight glass tubes and labelled. The physico chemical analysis of Plain Barbour’s surgical thread, Tilanala Ksharasurtra and Tilanla Kshara were done. Results: pH of Tilanala Ksharasutra is 9.65(+/-)0.10 and percentage of sodi-um, potassium, curcumin, turmeric, euphol and total alkalis present in Tilanala Ksharasutra are 2.04%, 21.79%, 0.039%, 3.06%, 2.25%, 22.64% respectively. Discussion and Conclusion: Tilanla Ksharasutra is not only indicated in Fistula-in-ano but also indicated in Pilonoidal sinus, haemorrhoid etc., To gain the ac-ceptance of the treatment at the global level present study was focused on standard operative procedure i.e., pharmaceutical and analytical study and exploring other drugs for the preparation of such magical Kalpana i.e., Ksharasutra.

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PHARMACEUTICAL & ANALYTICAL STUDY OF SAMAGUNA BALIJARITA RASA SINDURA

International Journal of Ayurveda and Pharma Research ◽

10.47070/ijapr.v8i10.1555 ◽

2020 ◽

pp. 108-116

Author(s):

Sorab Gaind ◽

Pradeep Agnihotri

Keyword(s):

Crystal Structure ◽

Analytical Study ◽

Total Mercury ◽

Xrd Analysis ◽

Physicochemical Analysis ◽

Total Sulfur ◽

Hexagonal Crystal Structure ◽

Hexagonal Crystal ◽

Unique Method ◽

Free Sulfur

Rasasindura is a one of Kuppipakva Rasayana a unique method of preparation and is one such imperative Kupipakwa Rasayana, referred to be Elixir of life. It is formulated by two fundamental substances of Rasashastra i.e., Shudha Parada and Shudha Gandhaka. It is said to be prepared by same process but with different proportion of Gandhaka, and accordingly various forms of Rasasindura are named as Ardhaguna, Samaguna, Dviguna, Triguna, Chaturguna, Panchaguna, Shadguna balijarita Rasasindura, where in, the therapeutic merits of Rasasindura and pharmaceutics of Rasasindura changes according to quantum of Gandhaka. Rasasindura is a Sagandha, Sagni and Bahirdhooma Kupipakwa Rasayana. Samaguna balijarita Rasasindur was prepared with equal quantities of Parada and Gandhaka by Kupipaka method in 20 hours and physicochemical analysis was carried out. Ash values in Samagunabalijarita Rasasindur were found to be 0.02%. Free mercury was nil in Samagunabalijarita Rasasindur where as its traces were present in the Kajjali. Free sulfur traces were present in Samagunabalijarita Rasasindur. Total mercury percentage in Samaguna Kajjali was 36.02%. Total mercury percentage in Samagunabalijarita Rasasindoor was 83.15%. Total sulfur percentage in Samagunabalijarita Rasasindoor was 13.06%. By XRD analysis Samagunabalijarita rasasindur was identified as Cinnabar having Hexagonal crystal structure with primitive lattice.

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Physico-chemical analysis of Haratala w.s.r. to its various Shodhana procedures

Journal of Ayurveda and Integrated Medical Sciences (JAIMS) ◽

10.21760/jaims.v2i2.7708 ◽

2017 ◽

Vol 2 (2) ◽

Author(s):

Bandeppa Sangolgi ◽

Ganapathi Rao ◽

Sangameshwar Benne

Keyword(s):

Chemical Analysis ◽

Analytical Study ◽

Operative Procedure ◽

Pharmacological Properties ◽

Arsenic Compounds ◽

Single Drug ◽

Physico Chemical ◽

The Media ◽

Pharmaceutical Processes

Kalpana is the process through which a substance can be transformed into the form of medicine according to the need. Samskaras are to be done for potentiating the drug or the formulation. Among all these pharmaceutical processes Shodhana is one of them. For a single drug many process of Shodhana have been mentioned. Arsenic compounds are being popularly used in Ayurveda therapeutics since centuries, Haratala being important among them. It is commonly used in treating the diseases like Sleshmaroga, Raktapitta, Vatarakta, Kustha etc. Haratala is called orpiment of yellow arsenic with two molecules of Arsenic and three molecules of Sulphur (AS2S3). Patra Haratala is Srestha and used for the present study. Haratala consumed without proper Shodhana shortens the life span, causes diseases of Kapha and Vata, Prameha, Santapa, Spotha, Snayu Sankocha. Hence Shodhana of Haratala is essential. There are different Medias explained in literature for Shodhana of Haratala. According to the media of purification the quality and pharmacological properties of Haratala will vary. Depending on the change in properties the therapeutic effect may also vary. The present study includes Shodhana of Patra Haratala as per Classical reference of Rasa Ratna Samucchaya where Shodana of Patra Haratala is done by Kushmanda Swarasa, Tila Kshara Jala and Churnodaka. Standard Operative Procedure of the process is done in the pharmaceutical study. The analytical study reveals the standards which can be given for Ashuddha Haratala and Shuddha Haratala of various Samples. The differences in the parameters reveal that there are some changes which give us the idea regarding role of a particular media in purification of a substance, where it adds some properties of the media used.

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Groundwater Quality Assessment of Firozabad City (India) – A Physico-Chemical Analysis

International Journal of Scientific Research ◽

10.15373/22778179/may2014/90 ◽

2012 ◽

Vol 3 (5) ◽

pp. 294-296

Author(s):

Nikhat Bano ◽

◽

Ateeque Ahmad

Keyword(s):

Chemical Analysis ◽

Groundwater Quality ◽

Quality Assessment ◽

Groundwater Quality Assessment ◽

Physico Chemical

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Structural, Thermal and Electrical Properties of Doped Poly(3,4 ethylenedioxythiophene)

Chemistry & Chemical Technology ◽

10.23939/chcht10.04.395 ◽

2016 ◽

Vol 10 (4) ◽

pp. 395-400 ◽

Cited By ~ 1

Author(s):

Deepali Kelkar ◽

◽

Ashish Chourasia ◽

◽

Keyword(s):

Crystal Structure ◽

Electrical Properties ◽

Xrd Analysis ◽

Structure Modification ◽

Camphorsulfonic Acid ◽

Thermal And Electrical Properties ◽

Ft Ir

Poly(3,4-ethylenedioxythiophene) (PEDOT) was chemically synthesized, undoped and then re-doped using FeCl3 as well as camphorsulfonic acid (CSA). FT-IR results confirm the nature of the synthesized and doped samples. XRD analysis indicates crystal structure modification after doping and was also used to calculate crystallinity of samples. Crystallinity increases after FeCl3 doping, whereas it reduces due to CSA doping. TGA-DTA results show reduction in Tg value for FeCl3 doped sample while it increases for CSA doped samples compared to that of undoped PEDOT. Reduction in Tg indicates plasticizing effect of FeCl3 whereas increase in Tg show anti-plasticizing effect of CSA in PEDOT. Conductivity value () increases by two orders of magnitude after doping. Log vs. 1/T graph show metallic nature of undoped PEDOT above 308 K, however both doped samples show semiconducting nature from 301 to 383 K.

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