Tip of the iceberg: Immunohistochemical markers reveal malignant transformation underneath a vocal polyp surface
Keyword(s):
Novel molecular techniques including markers of laryngeal carcinogenesis could improve the difficult diagnosis of a wide array of laryngeal polypoid changes. The case reported herein shows that not every clinically diagnosed vocal fold polyp is a benign lesion as mostly considered in the literature. Further assessment including carcinogenesis markers detected a nest of micro-invasive squamous cell carcinoma. Therefore, we recommend biopsy backed up with immunohistochemical analysis whenever there is a suspicious polypoid formation in order to exclude or confirm a malignant transformation because of the possibility of multi-focal growth in the active laryngeal epithelium.
2011 ◽
Vol 101
(4)
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pp. 360-362
1986 ◽
Vol 11
(2)
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pp. 273-275
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2020 ◽
Vol 6
(10)
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pp. 1783
Keyword(s):
2021 ◽
Vol 49
(2)
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pp. 030006052098154
2015 ◽
Vol 105
(4)
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pp. 374-376