Faculty Opinions recommendation of Comparison of risk factors for invasive squamous cell carcinoma and adenocarcinoma of the cervix: collaborative reanalysis of individual data on 8,097 women with squamous cell carcinoma and 1,374 women with adenocarcinoma from 12 epidemiological studies.

2007 ◽  
Author(s):  
Giovanni Scambia
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Epidemiological Studies ◽  
Invasive Squamous Cell Carcinoma ◽  
Individual Data

scholarly journals Tongue Squamous Cell Carcinoma in a Young Patient Free of Risk Factors:

2014 ◽  
Vol 4 (1) ◽  
pp. 43-47
Author(s):  
Abdulrhman A. Abulaban ◽  
Lujain A. Khoja ◽  
Sara S. Baghlaf ◽  
Moataz M. Aldahlawi ◽  
Mahmoud S. Al-Ahwal
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Recognition ◽  
Tongue Squamous Cell Carcinoma ◽  
Invasive Squamous Cell Carcinoma ◽  
Resonance Imaging ◽  
Positron Emission ◽  
Supraomohyoid Neck Dissection

Tongue squamous cell carcinoma progresses from an oral premalignant lesion to invasive squamous cell carcinoma. The incidence of tongue carcinoma has been increasing markedly even in patients free of risk factors as the reporting case of a 22-years-old female complaining of small tender whitish discoloration over the left side of the tongue. First, there was a dilemma in the diagnosis taking in consideration that she is young and free of risk factor, but the magnetic resonance imaging of the head and neck showed a heterogenous mass in the tongue with deep muscular invasion. After the result of positron emission tomography-computed tomography, the patient underwent left hemiglossectomy with left supraomohyoid neck dissection and histopathology report showed invasive squamous cell carcinoma. Thus, she was referred for adjuvant radiotherapy. At this point, it emphasized that early recognition is essential; as an extensive history should be obtained from the patient that includes the symptoms emerged and risk factors.

Penile Invasive Squamous Cell Carcinoma: Analysis of Incidence, Mortality Trends, and Geographic Distribution in Canada

2019 ◽  
Vol 24 (2) ◽  
pp. 124-128 ◽  
Author(s):  
François Lagacé ◽  
Feras M. Ghazawi ◽  
Michelle Le ◽  
Evgeny Savin ◽  
Andrei Zubarev ◽  
...  
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Invasive Squamous Cell Carcinoma ◽  
Crude Incidence ◽  
Incidence And Mortality ◽  
Adjusted Incidence

Background Penile invasive squamous cell carcinoma (SCC) is a rare disease with several known risk factors. However, few studies have assessed its incidence, mortality, and temporal trends. Objective Our objectives are to analyze the epidemiology of penile SCC in Canada and to examine patient distribution with this cancer across Canada in order to elucidate population risk factors. Methods Three independent cancer registries were used to retrospectively analyze demographic data from Canadian men diagnosed with penile invasive SCC between 1992 and 2010. The Canadian Census of Population was used to calculate incidence and mortality rates at the province and Forward Sortation Area levels. Results The overall age-adjusted incidence rate was 6.08 cases per million males. Four provinces with statistically significantly higher incidence rates were identified. The national crude incidence rates increased linearly between 1992 and 2010, whereas the age-adjusted incidence rates showed no significant increase during this time period. The overall age-adjusted mortality rate was 1.88 deaths per million males per year. The province of Saskatchewan had significantly higher mortality rates. There was no increase in crude or age-adjusted mortality rates between 1992 and 2010. There was a significant positive correlation between incidence rates and obesity, Caucasian ethnicity, and lower socioeconomic status. Conclusion This study was able to establish geographic variation for this malignancy at the provincial level. Although there are many established risk factors for penile SCC, our results suggest that the increase in crude incidence rates observed is largely due to the aging population.

scholarly journals Risk factors for invasive squamous cell carcinoma of the vulva and vagina—Population-based case–control study in Denmark

2008 ◽  
Vol 122 (12) ◽  
pp. 2827-2834 ◽  
Author(s):  
Birgitte S. Madsen ◽  
Helle L. Jensen ◽  
Adriaan J.C. van den Brule ◽  
Jan Wohlfahrt ◽  
Morten Frisch
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Invasive Squamous Cell Carcinoma ◽  
Control Study

scholarly journals Tongue Squamous Cell Carcinoma in a Young Patient Free of Risk Factors:

2014 ◽  
Vol 4 (1) ◽  
pp. 43-47
Author(s):  
Abdulrhman A. Abulaban ◽  
Lujain A. Khoja ◽  
Sara S. Baghlaf ◽  
Moataz M. Aldahlawi ◽  
Mahmoud S. Al-Ahwal
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Recognition ◽  
Tongue Squamous Cell Carcinoma ◽  
Invasive Squamous Cell Carcinoma ◽  
Resonance Imaging ◽  
Positron Emission ◽  
Supraomohyoid Neck Dissection

Tongue squamous cell carcinoma progresses from an oral premalignant lesion to invasive squamous cell carcinoma. The incidence of tongue carcinoma has been increasing markedly even in patients free of risk factors as the reporting case of a 22-years-old female complaining of small tender whitish discoloration over the left side of the tongue. First, there was a dilemma in the diagnosis taking in consideration that she is young and free of risk factor, but the magnetic resonance imaging of the head and neck showed a heterogenous mass in the tongue with deep muscular invasion. After the result of positron emission tomography-computed tomography, the patient underwent left hemiglossectomy with left supraomohyoid neck dissection and histopathology report showed invasive squamous cell carcinoma. Thus, she was referred for adjuvant radiotherapy. At this point, it emphasized that early recognition is essential; as an extensive history should be obtained from the patient that includes the symptoms emerged and risk factors.

Rediscussing the Role of Traditional Risk Factors in Young Adults With Oral Squamous Cell Carcinoma

2020 ◽  
Vol 40 (12) ◽  
pp. 6987-6995
Author(s):  
NORBERT NECKEL ◽  
MARCO MICHAEL ◽  
DANIEL TROELTZSCH ◽  
JONAS WÜSTER ◽  
STEFFEN KOERDT ◽  
...  
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Young Adults ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Traditional Risk Factors

scholarly journals Leiomyosarcoma of the Tracheostomy Site in a Patient with History of Laryngeal Squamous Cell Carcinoma

2021 ◽  
pp. 912-917
Author(s):  
Zainub Ajmal ◽  
Abdul Moiz Khan ◽  
Lezah McCarthy ◽  
Allison Lupinetti ◽  
Syed Mehdi
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
English Literature ◽  
Neck Region ◽  
Multiple Risk Factors ◽  
History Of ◽  
Rare Malignancy

Leiomyosarcoma (LMS) of the trachea is an extremely rare malignancy with only a few reported cases in English literature. As such the diagnosis can be frequently missed or delayed. We present a case of a 69-year-old male who underwent tracheostomy for airway obstruction secondary to glottic squamous cell carcinoma and treated definitely with radiation therapy. Subsequently, the patient developed LMS of the tracheostomy site. The case further details multiple risk factors that could contribute to development of LMS including radiation exposure, prior malignancy, and chronic inflammation. These risk factors have been well established for LMS in other sites but less so in the head and neck region, which is the subject of our discussion. We also review the current guidelines for head and neck as well as limb sarcomas and discussed role of surgery or radiation and their accompanying challenges in management of this rare malignancy.

scholarly journals A nomogram to predict lymph node metastasis risk for early esophageal squamous cell carcinoma

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaofeng Duan ◽  
Xiaobin Shang ◽  
Jie Yue ◽  
Zhao Ma ◽  
Chuangui Chen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Derivation Cohort ◽  
Node Metastasis

Abstract Background A nomogram was developed to predict lymph node metastasis (LNM) for patients with early-stage esophageal squamous cell carcinoma (ESCC). Methods We used the clinical data of ESCC patients with pathological T1 stage disease who underwent surgery from January 2011 to June 2018 to develop a nomogram model. Multivariable logistic regression was used to confirm the risk factors for variable selection. The risk of LNM was stratified based on the nomogram model. The nomogram was validated by an independent cohort which included early ESCC patients underwent esophagectomy between July 2018 and December 2019. Results Of the 223 patients, 36 (16.1%) patients had LNM. The following three variables were confirmed as LNM risk factors and were included in the nomogram model: tumor differentiation (odds ratio [OR] = 3.776, 95% confidence interval [CI] 1.515–9.360, p = 0.004), depth of tumor invasion (OR = 3.124, 95% CI 1.146–8.511, p = 0.026), and tumor size (OR = 2.420, 95% CI 1.070–5.473, p = 0.034). The C-index was 0.810 (95% CI 0.742–0.895) in the derivation cohort (223 patients) and 0.830 (95% CI 0.763–0.902) in the validation cohort (80 patients). Conclusions A validated nomogram can predict the risk of LNM via risk stratification. It could be used to assist in the decision-making process to determine which patients should undergo esophagectomy and for which patients with a low risk of LNM, curative endoscopic resection would be sufficient.

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