scholarly journals Age-Related Changes in Gait Velocity and Leg Extension Power in Middle-Aged and Elderly People

2000 ◽  
Vol 10 (1sup) ◽  
pp. 77-81 ◽  
Author(s):  
Rumi Kozakai ◽  
Shigeki Tsuzuku ◽  
Kyonosuke Yabe ◽  
Fujiko Ando ◽  
Naoakira Niino ◽  
...  
1982 ◽  
Vol 55 (2) ◽  
pp. 559-562
Author(s):  
Claire Etaugh ◽  
Sharon Weber

48 female and 48 male college students used the Bern Sex-role Inventory to describe either a young or middle-aged woman or man. Female subjects perceived that women become increasingly feminine and less androgynous with age. No age-related changes were perceived in men's sex-role behaviors.


1999 ◽  
Vol 89 (8) ◽  
pp. 383-391 ◽  
Author(s):  
W Lynch ◽  
J Mooney

A device was constructed to assess two-point discrimination in the plantar skin of younger, middle-aged, and older adults. The device consisted of paired filaments, each delivering a tip force of 4.56 log units (equivalent to 3.63 g), at a fixed distance apart. Statistical analysis showed significant differences in two-point discrimination accuracy between these groups of subjects. Younger subjects showed greater accuracy of plantar two-point discrimination than either middle-aged or older subjects, with an apparent inverse linear relationship between subject age and plantar two-point discrimination ability. A model to assess age-related changes in two-point discrimination is presented.


1987 ◽  
Vol 62 (3) ◽  
pp. 1331-1334 ◽  
Author(s):  
S. L. Whaley ◽  
B. A. Muggenburg ◽  
F. A. Seiler ◽  
R. K. Wolff

Tracheal mucous velocity measurements were made in 24 beagle dogs in five age groups, using a gamma camera to detect movement of instilled 99mTc-macroaggregated albumin. Age groups were defined as immature (9–10 mo), young adult (2.8–3.0 yr), middle aged (6.7–6.9 yr), mature (9.6–9.8 yr), and aged dogs (13.6–16.2 yr). Mean velocities were 3.6 +/- 0.4 (SE) mm/min in the immature dogs, 9.7 +/- 0.6 mm/min in the young adults, 6.9 +/- 0.5 mm/min in the middle-aged dogs, 3.5 +/- 0.8 mm/min in the mature dogs, and 2.9 +/- 0.5 mm/min in the aged dogs. Tracheal mucous velocity was significantly (P less than 0.05) greater in the young adult and middle-aged groups compared with the immature, mature, and aged dogs. This pattern of age-related changes was noted to be similar to age-related changes described for certain pulmonary function measurements.


2017 ◽  
Vol 49 (8) ◽  
pp. 400-415 ◽  
Author(s):  
Sivasai Balivada ◽  
Chanran K. Ganta ◽  
Yongqing Zhang ◽  
Hitesh N. Pawar ◽  
Richard J. Ortiz ◽  
...  

The rostral ventrolateral medulla (RVLM) is an area of the brain stem that contains diverse neural substrates that are involved in systems critical for physiological function. There is evidence that aging affects some neural substrates within the RVLM, although age-related changes in RVLM molecular mechanisms are not well established. The goal of the present study was to characterize the transcriptomic profile of the aging RVLM and to test the hypothesis that aging is associated with altered gene expression in the RVLM, with an emphasis on immune system associated gene transcripts. RVLM tissue punches from young, middle-aged, and aged F344 rats were analyzed with Agilent’s whole rat genome microarray. The RVLM gene expression profile varied with age, and an association between chronological age and specific RVLM gene expression patterns was observed [ P < 0.05, false discovery rate (FDR) < 0.3]. Functional analysis of RVLM microarray data via gene ontology profiling and pathway analysis identified upregulation of genes associated with immune- and stress-related responses and downregulation of genes associated with lipid biosynthesis and neurotransmission in aged compared with middle-aged and young rats. Differentially expressed genes associated with the complement system and microglial cells were further validated by quantitative PCR with separate RVLM samples ( P < 0.05, FDR < 0.1). The present results have identified age-related changes in the transcriptomic profile of the RVLM, modifications that may provide the molecular backdrop for understanding age-dependent changes in physiological regulation.


Author(s):  
Антонина Владимировна Алексеева ◽  
Анатолий Яковлевич Рыжов ◽  
Данила Игоревич Игнатьев

Исследованы антропометрические показатели и параметры состава тела у лиц среднего возраста. Установлено, что некоторые калиперометрические показатели испытывают различие у мужчин и женщин. Калиперометрические показатели величины кожных покровов спины, медиальной и латеральной поверхностей бедер характеризуются тесными положительными корреляциями. Anthropometric indicators and parameters of body composition in middle-aged people were studied. It is established that some caliperometric indicators experience a difference in men and women. Caliperometric indicators of the size of the skin of the back, medial and lateral surfaces of the thighs are characterized by close positive correlations.


2020 ◽  
Vol 45 (1) ◽  
pp. 78-88
Author(s):  
Takeshi Nakagawa ◽  
Yukiko Nishita ◽  
Chikako Tange ◽  
Makiko Tomida ◽  
Kaori Kinoshita ◽  
...  

Prior evidence suggests that subjective well-being (SWB) remains relatively stable across adulthood. However, longitudinal evidence is sparse except in Western societies such as North America and Western Europe. We examined age-related changes in SWB (life satisfaction, positive affect, and negative affect) among middle-aged and older Japanese. We applied multilevel growth models to 14-year seven-wave longitudinal data of a dynamic cohort study. A total of 3,890 participants aged 40–81 at first assessment were included in the analysis. The longitudinal results demonstrated differential trajectories of SWB. Life satisfaction exhibited an accelerated increase in middle age but decreased and leveled off in old age. Positive affect increased in midlife and declined in late life. Negative affect remained stable in middle age but increased in old age. Demographics, health, and methodological correlates did not fully account for age-related changes in SWB. Of note, increases in negative affect in old age remained evident even after controlling for the correlates. In conclusion, life satisfaction was stable across adulthood, which was not the case with positive and negative affect. We discussed the possible mechanisms in these observed trajectories of SWB, in particular, negative affect in late life.


2019 ◽  
Vol 27 (6) ◽  
pp. 854-863 ◽  
Author(s):  
Mckenna E. Williams ◽  
Lisa V. Graves ◽  
Emily J. Van Etten ◽  
Heather M. Holden ◽  
Lisa Delano-Wood ◽  
...  

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