scholarly journals Burden of Cervical Cancer in the Eastern Mediterranean Region During the Years 2000 and 2017: Retrospective Data Analysis of the Global Burden of Disease Study

10.2196/22160 ◽  
2021 ◽  
Vol 7 (5) ◽  
pp. e22160
Author(s):  
Fereshteh Safaeian ◽  
Shidrokh Ghaemimood ◽  
Ziad El-Khatib ◽  
Sahba Enayati ◽  
Roksana Mirkazemi ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Mortality Rate ◽  
Cancer Mortality ◽  
Eastern Mediterranean ◽  
Eastern Mediterranean Region ◽  
Absolute Number ◽  
Age Group ◽  
Cervical Cancer Mortality ◽  
The Absolute ◽  
Year 2000

Background Cervical cancer is a growing health concern, especially in resource-limited settings. Objective The objective of this study was to assess the burden of cervical cancer mortality and disability-adjusted life years (DALYs) in the Eastern Mediterranean Region (EMR) and globally between the years 2000 and 2017 by using a pooled data analysis approach. Methods We used an ecological approach at the country level. This included extracting data from publicly available databases and linking them together in the following 3 steps: (1) extraction of data from the Global Burden of Disease (GBD) study in the years 2000 and 2017, (2) categorization of EMR countries according to the World Bank gross domestic product per capita, and (3) linking age-specific population data from the Population Statistics Division of the United Nations (20-29 years, 30-49 years, and >50 years) and GBD’s data with gross national income per capita and globally extracted data, including cervical cancer mortality and DALY numbers and rates per country. The cervical cancer mortality rate was provided by the GBD study using the following formula: number of cervical cancer deaths × 100,000/female population in the respective age group. Results The absolute number of deaths due to cervical cancer increased from the year 2000 (n=6326) to the year 2017 (n=8537) in the EMR; however, the mortality rate due to this disease decreased from the year 2000 (2.7 per 100,000) to the year 2017 (2.5 per 100,000). According to age-specific data, the age group ≥50 years showed the highest mortality rate in both EMR countries and globally, and the age group of 20-29 years showed the lowest mortality rate both globally and in the EMR countries. Further, the rates of cervical cancer DALYs in the EMR were lower compared to the global rates (2.7 vs 6.8 in 2000 and 2.5 vs 6.8 in 2017 for mortality rate per 100,000; 95.8 vs 222.2 in 2000 and 86.3 vs 211.8 in 2017 for DALY rate per 100,000; respectively). However, the relative difference in the number of DALYs due to cervical cancer between the year 2000 and year 2017 in the EMR was higher than that reported globally (34.9 vs 24.0 for the number of deaths and 23.5 vs 18.1 for the number of DALYs, respectively). Conclusions We found an increase in the burden of cervical cancer in the EMR as per the data on the absolute number of deaths and DALYs. Further, we found that the health care system has an increased number of cases to deal with, despite the decrease in the absolute number of deaths and DALYs. Cervical cancer is preventable if human papilloma vaccination is taken and early screening is performed. Therefore, we recommend identifying effective vaccination programs and interventions to reduce the burden of this disease.

scholarly journals Burden of Cervical Cancer in the Eastern Mediterranean Region During the Years 2000 and 2017: Retrospective Data Analysis of the Global Burden of Disease Study (Preprint)

2020 ◽  
Author(s):  
Fereshteh Safaeian ◽  
Shidrokh Ghaemimood ◽  
Ziad El-Khatib ◽  
Sahba Enayati ◽  
Roksana Mirkazemi ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Mortality Rate ◽  
Cancer Mortality ◽  
Eastern Mediterranean ◽  
Eastern Mediterranean Region ◽  
Absolute Number ◽  
Age Group ◽  
Cervical Cancer Mortality ◽  
The Absolute ◽  
Year 2000

BACKGROUND Cervical cancer is a growing health concern, especially in resource-limited settings. OBJECTIVE The objective of this study was to assess the burden of cervical cancer mortality and disability-adjusted life years (DALYs) in the Eastern Mediterranean Region (EMR) and globally between the years 2000 and 2017 by using a pooled data analysis approach. METHODS We used an ecological approach at the country level. This included extracting data from publicly available databases and linking them together in the following 3 steps: (1) extraction of data from the Global Burden of Disease (GBD) study in the years 2000 and 2017, (2) categorization of EMR countries according to the World Bank gross domestic product per capita, and (3) linking age-specific population data from the Population Statistics Division of the United Nations (20-29 years, 30-49 years, and >50 years) and GBD’s data with gross national income per capita and globally extracted data, including cervical cancer mortality and DALY numbers and rates per country. The cervical cancer mortality rate was provided by the GBD study using the following formula: number of cervical cancer deaths × 100,000/female population in the respective age group. RESULTS The absolute number of deaths due to cervical cancer increased from the year 2000 (n=6326) to the year 2017 (n=8537) in the EMR; however, the mortality rate due to this disease decreased from the year 2000 (2.7 per 100,000) to the year 2017 (2.5 per 100,000). According to age-specific data, the age group ≥50 years showed the highest mortality rate in both EMR countries and globally, and the age group of 20-29 years showed the lowest mortality rate both globally and in the EMR countries. Further, the rates of cervical cancer DALYs in the EMR were lower compared to the global rates (2.7 vs 6.8 in 2000 and 2.5 vs 6.8 in 2017 for mortality rate per 100,000; 95.8 vs 222.2 in 2000 and 86.3 vs 211.8 in 2017 for DALY rate per 100,000; respectively). However, the relative difference in the number of DALYs due to cervical cancer between the year 2000 and year 2017 in the EMR was higher than that reported globally (34.9 vs 24.0 for the number of deaths and 23.5 vs 18.1 for the number of DALYs, respectively). CONCLUSIONS We found an increase in the burden of cervical cancer in the EMR as per the data on the absolute number of deaths and DALYs. Further, we found that the health care system has an increased number of cases to deal with, despite the decrease in the absolute number of deaths and DALYs. Cervical cancer is preventable if human papilloma vaccination is taken and early screening is performed. Therefore, we recommend identifying effective vaccination programs and interventions to reduce the burden of this disease.

The potential impact of the Deep South Network for Cancer Control on cervical cancer mortality among black females in historically underserved areas of Alabama.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 6559-6559
Author(s):  
Karan P. Singh ◽  
Bradford E Jackson ◽  
Rohit P Ojha ◽  
Chenguang Wang ◽  
Minyong Uhm ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Mortality Rate ◽  
Cancer Mortality ◽  
Cancer Control ◽  
Comprehensive Cancer Center ◽  
Cancer Center ◽  
Deep South ◽  
Intervention Period ◽  
Black Females ◽  
Cervical Cancer Mortality

6559 Background: Racial disparities in cervical cancer mortality are well-documented. The Deep South Network for Cancer Control (DSNCC) was implemented in 2000 to address this disparity by targeting blacks for cervical cancer screening in historically underserved areas of Alabama and Mississippi. We aimed to assess whether the implementation of the DSNCC has improved cervical cancer mortality among black females in Alabama. Methods: We used data from the University of Alabama-Birmingham (UAB) Comprehensive Cancer Center Tumor Registry, which comprises all cancer cases treated in the UAB Health system. We selected all black females diagnosed with cervical cancer in the pre-DSNCC (January 1995-December 1999) and post-DSNCC (January 2001-December 2005) periods. Person time was calculated for up to five years post diagnosis. We estimated hazard ratios (HRs) and corresponding 95% confidence limits (CLs) using Cox proportional hazards models. The cervical cancer mortality rate of black females who resided in DSNCC-targeted Alabama counties was compared to non-DSNCC-targeted Alabama counties before and after implementation of the DSNCC. Results: The study population comprised 129 black females diagnosed with cervical cancer pre-DSNCC and 175 diagnosed post-DSNCC. During the pre-intervention period, black females in DSNCC-targeted counties had a two-fold higher cervical cancer mortality rate than black females in non-DSNCC-targeted counties (HR=2.0; 95%CL: 1.10, 3.72). During the post-intervention period, black females in DSNCC-targeted counties had nearly a two-fold lower cervical cancer mortality rate than black females in non-DSNCC-targeted counties (HR=0.54; 95%CL: 0.35, 0.87). Conclusions: Our results suggest that the DSNCC interventions are improving cervical cancer outcomes among black females in historically underserved areas of Alabama. The current analysis was only able to examine the initial 5 years after implementation of the DSNCC; continued assessment of outcomes would be useful for assessing the long-term impact of the DSNCC.

scholarly journals INCIDENCE AND MORTALITY OF CERVICAL CANCER IN THE OMSK REGION

2019 ◽  
Vol 18 (5) ◽  
pp. 12-17
Author(s):  
O. P. Goleva ◽  
Z. B. Tasova ◽  
O. P. Prudnikova
Keyword(s):  
Cervical Cancer ◽  
Mortality Rate ◽  
Cancer Incidence ◽  
Cancer Mortality ◽  
Mortality Rates ◽  
Rural Populations ◽  
Advanced Cervical Cancer ◽  
Cervical Cancer Incidence ◽  
Incidence And Mortality ◽  
Cervical Cancer Mortality

The purpose of the study was a comparative assessment of the cervical cancer incidence and mortality among females in urban and rural populations of the Omsk region.Material and Methods. The study included females aged over 18 years from urban and rural areas of the Omsk region. According to population-based cancer registry data for the period 2004–16, the crude cancer incidence and mortality rates in urban and rural populations were calculated. The variational and correlation analyzes were used, the differences were assessed using Student t-test.Results. During 2004–16, the cervical cancer incidence among females of the Omsk region showed an increasing tendency, reaching a peak incidence in women aged 35–54. Concerning the cervical cancer mortality rate, it tended to decrease. For rural females, the cervical cancer mortality rate decreased from 10.8 to 9.7 per 100,000 females (p>0.05). For urban females, the mortality rate decreased from 9.2 to 7.5 per 100,000 females (p>0.05). No significant differences in the mortality rates between urban and rural females were found (p>0.05). The tendency towards decreased incidence of advanced cervical cancer (the average decrease being 3.3 % for rural females and 2.8 % for urban females, p>0.05) and increased incidence of early stage cervical cancer (the average rise being 1.8 % and 1.9 %, respectively) was observed.Conclusion. In the Omsk region, the cervical cancer mortality rate for both rural and urban females showed a tendency to decrease. During the study period, the incidence of cervical cancer had increased; however the incidence of advanced cervical cancer had decreased.

Time trends and age-period-cohort analysis of cervical cancer mortality rate in Brazil

2020 ◽  
Vol 25 ◽  
pp. 100230
Author(s):  
Diego Hernan Giunta ◽  
Mirian Carvalho de Souza ◽  
Maria Beatriz Kneipp Dias ◽  
Moyses Szklo ◽  
Liz Maria de Almeida
Keyword(s):  
Cervical Cancer ◽  
Mortality Rate ◽  
Cancer Mortality ◽  
Time Trends ◽  
Cohort Analysis ◽  
Cervical Cancer Mortality

scholarly journals Effectiveness of Cervical Cancer Screening Over Cervical Cancer Mortality Among Japanese Women

2006 ◽  
Vol 36 (8) ◽  
pp. 511-518 ◽  
Author(s):  
Khandoker Aklimunnessa ◽  
Mitsuru Mori ◽  
M. M. H. Khan ◽  
Fumio Sakauchi ◽  
Tatsuhiko Kubo ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Cancer Mortality ◽  
Japanese Women ◽  
Cervical Cancer Mortality

European trends in cervical cancer mortality in relation to national screening programs, 1985–2014

2021 ◽  
Vol 74 ◽  
pp. 102002
Author(s):  
Ingrid Salciccioli ◽  
Charlie D. Zhou ◽  
Emeka C. Okonji ◽  
Joseph Shalhoub ◽  
Justin D. Salciccioli ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Mortality ◽  
Screening Programs ◽  
Cervical Cancer Mortality

scholarly journals Analysis of cervical cancer mortality rate trends in Natal-RN, Brazil, between 2000 and 2012

2019 ◽  
Vol 21 (2) ◽  
pp. 161-167
Author(s):  
Paulo Roberto Medeiros Azevedo ◽  
Joyce Bezerra Rocha ◽  
Thales Allyrio Araújo de Medeiros Fernandes ◽  
José Veríssimo Fernandes
Keyword(s):  
Cervical Cancer ◽  
Cancer Mortality ◽  
Empirical Bayes ◽  
Family Income ◽  
Screening Program ◽  
Mortality Rates ◽  
P Value ◽  
Average Family ◽  
Historical Series ◽  
Cervical Cancer Mortality

Objective To describe cervical cancer mortality rates and their corresponding trends, and to analyze the spatial correlations of this type of cancer in Natal-RN, Brazil, between 2000 and 2012.Materials and Methods The simple linear regression model, the empirical Bayes method and the Global Moran's index were used for the statistical analysis.Results The mortality coefficient of cervical cancer in Natal, standardized by age range, was 5.5 per 100 000 women. All historical series for the coefficients studied were classifiedas stable. The Global Moran's index obtained was 0.048, with a p-value for the spatial test correlation between neighborhoods of 0.300. The average family income by neighborhood showed no significant correlation to cervical cancer mortality rates.Conclusion This study found a temporal stabilization and spatial independence trend of cervical cancer mortality rates in women from Natal, as well as the absence of correlationbetween these rates and the average family income of the of the participating women distributed by neighborhoods. In view of this, changes in the public policies should be made aimed at preventing the disease; adopting these measures could positively impact the screening program, improving the coverage of Pap smears and immunization campaigns against HPV, in order to reverse this trend and achieve a reduction of mortality rates.

Relations of cervical cancer mortality with the population's number and distribution in Republics, located in Siberia (2007-2018)

2020 ◽  
pp. 46-49
Author(s):  
I.V. Kononova ◽  
M.P. Kirillina ◽  
S.I. Sofronova ◽  
P.V. Nikiforov ◽  
V.A. Alekseev ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Mortality ◽  
Cervical Cancer Mortality
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