scholarly journals Validation of a portable game controller to assess peak expiratory flow against conventional spirometry in children: A cross-sectional study (Preprint)

2020 ◽  
Author(s):  
Khadidja Chelabi ◽  
Fabio Balli ◽  
Myriam Bransi ◽  
Yannick Gervais ◽  
Clement Marthe ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Peak Expiratory Flow ◽  
Pulmonary Function Tests ◽  
Airflow Obstruction ◽  
Forced Expiratory Volume ◽  
Cross Sectional ◽  
Disease Evolution ◽  
Game Controller ◽  
Feedback Questionnaire ◽  
Expiratory Flow

BACKGROUND International asthma guidelines recommend the monitoring of peak expiratory flow (PEF) as part of asthma self-management in children and adolescents who poorly perceive airflow obstruction, those with a history of severe exacerbations, or have difficult to control asthma. Measured with a peak flow meter, PEF represents a person’s maximum speed of expiration and helps individuals to follow their disease evolution and ultimately to prevent asthma exacerbations. However, adherence to this practice is poor, particularly in the pediatric population. To address this, we developed an interactive serious game consisting of a portable game controller that can transduce a signal from the breath to generate a PEF value when coupled with a tablet-based game. OBJECTIVE We evaluated the concordance between PEF values obtained with the game controller (PEFGC) and various measures derived from conventional pulmonary function tests (i.e spirometry) and we synthesized the participants’ feedback. METHODS In this cross-sectional multicenter study, 158 children aged 8-15 years old with a diagnosis or suspicion of asthma performed spirometry and played with the game in one of 2 hospital university centers. We evaluated the correlation between PEFGC and spirometry measurements, including PEF values (PEFspiro), forced expiratory volume in 1 second (FEV1) and forced expiratory volume at 25-75% of pulmonary volume (FEF25-75), using Spearman correlation. A Bland-Altman plot was generated for comparison of PEFGC against PEFspiro. A post-game user feedback questionnaire was administered and analyzed. RESULTS The participants had a mean age (SD) of 10.9 2.5) years, 44% were female, and 88.6% Caucasians. On average, their pulmonary function were normal, including FEV1, PEF and FEV1/FVC. The PEFGC was reproducible in 96.2% of participants according to standardized criteria. The PEFGC presented a good correlation with PEFspiro (r=0.83, p<0.001), with FEV1 (r=0.74, p<0.001) and with FEF25-75 (r=0.65, p<0.001). The PEFGC presented an expected mean bias of -36.4 L/min as compared to PEFspiro. The participants’ feedback was strongly positive with 78.4% reporting they would use the game if they had it at home. CONCLUSIONS The game controller developed is an interactive tool appreciated by children with asthma and whose values are reproducible with a good correlation when compared to conventional spirometry. Future studies are necessary to evaluate the clinical impact this novel tool might have on asthma management and its potential use in an out-of-hospital setting. CLINICALTRIAL

scholarly journals Effectiveness of septoplasty on pulmonary function tests in symptomatic deviated nasal septum cases: a prospective study

2018 ◽  
Vol 4 (3) ◽  
pp. 800 ◽  
Author(s):  
Vidya Bhargavan Panicker ◽  
B.P. Belaldavar
Keyword(s):  
Pulmonary Function ◽  
Peak Expiratory Flow ◽  
Nasal Septum ◽  
Pulmonary Function Tests ◽  
Demographic Data ◽  
Forced Expiratory Volume ◽  
Deviated Nasal Septum ◽  
Pulmonary Functions ◽  
Function Tests ◽  
Expiratory Flow

<p class="abstract"><strong>Background:</strong> Deviation of normal pulmonary functions leads to dysfunction of the respiratory system and this affects the functions and vitality of other related systems. Pulmonary function tests give valuable information on the state of airways, lung volumes and lung function. Hence, the present study aimed to evaluate the effectiveness of septoplasty on pulmonary function tests in symptomatic deviated nasal septum cases.</p><p class="abstract"><strong>Methods:</strong> A total of 35 patients (septoplasty: 31; septorhinoplasty: 4) with deviated nasal septum were involved in the study. Demographic data, clinical and physical examination including anterior and posterior rhinoscopy was performed. RMS Helios 702 spirometer was used to perform pre- and postoperative pulmonary function tests. Forced vital capacity (FVC), forced expiratory volume (FEV1) in 1 second, peak expiratory flow rate, and the ratio of FEV1 to FVC were the parameters measured. SPSSV. 17 was used to analyse the data.  </p><p class="abstract"><strong>Results:</strong> The deviation was most commonly seen on the left side (54%), affecting mostly the cartilaginous septum (54%). Among patients with septoplasty, the postoperative values of FVC (p&lt;0.05), FEV1 (p&lt;0.05), and peak expiratory flow (p&lt;0.05) were higher than the preoperative values and the results were statistically significant. Age, gender, laterality and duration of deviation, headache and inferior turbinate hypertrophy did not play a significant role in the enhancement of pulmonary functions after septoplasty.</p><p class="abstract"><strong>Conclusions:</strong> A favorable outcome in pulmonary function was observed in patients with deviated nasal septum after septoplasty. However, due to limited sample size, it is advisable to conduct the study in a larger sample to validate these results.</p>

Pulmonary function severity in relation to interleukin-23 levels in patients with psoriasis vulgaris

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Vasann Saranya ◽  
Saranya Kuppusamy ◽  
Pravati Pal ◽  
Munisamy Malathi ◽  
Medha Rajappa ◽  
...  
Keyword(s):  
Lung Function ◽  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Forced Expiratory Volume ◽  
Control Group ◽  
Chronic Obstructive ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Expiratory Flow ◽  
Interleukin 23

AbstractBackgroundInterleukin-23 (IL-23), a key inflammatory regulator in the pathogenesis of psoriasis, is suspected to play a role in the onset of pulmonary dysfunction (chronic obstructive pulmonary disease) in psoriasis. Despite that, pulmonary function tests are rarely studied in these subjects. This study aims to seek a possible relation between pulmonary function in psoriasis patients serum IL-23.MethodsFor this analytical cross-sectional study, male psoriasis patients in the age group of 25–45 years were recruited from dermatology out patient department (n = 40). Age and BMI matched apparently healthy individuals were recruited as control group (n = 40). After obtaining demographic and personal details, anthropometric parameters and blood pressure were recorded. The severity of psoriasis was assessed using Psoriasis Area and Severity Index score. Pulmonary function was assessed using computerized spirometry, and serum IL-23 was measured using ELISA.ResultsForced vital capacity, forced expiratory volume in 1 s, peak expiratory flow rate, and forced expiratory flow at 25%–75% of the pulmonary volume (FEF25%–75%) were significantly reduced in psoriasis. Based on the percentage of predicted values FEF25%–75% was significantly reduced in psoriasis. Serum IL-23 (pg/mL) was significantly higher in psoriasis. The increase in IL-23 in psoriasis subjects does not correlate with their pulmonary function.ConclusionsPsoriasis may be associated with a reduced lung function even when the disease is in the mild stage. Increased IL-23 found in these subjects is suggestive of systemic inflammation, which indirectly lowers lung function.

scholarly journals Pulmonary Function Changes Before and After Mitral Valve Surgery in Severe Mitral Stenosis

2018 ◽  
Vol 02 (02) ◽  
pp. 079-083
Author(s):  
Manoj Kumar Sahu ◽  
Mayank Yadav ◽  
Milind Padmakar Hote ◽  
Sarvesh Pal Singh ◽  
Shiv Kumar Choudhary
Keyword(s):  
Mitral Valve ◽  
Pulmonary Function ◽  
Mitral Stenosis ◽  
Pulmonary Function Tests ◽  
Nyha Class ◽  
Forced Expiratory Volume ◽  
Mitral Valve Surgery ◽  
Valve Surgery ◽  
Female Ratio ◽  
Expiratory Flow

Abstract Objective This study was undertaken to assess the pulmonary functions in the patients with predominant severe mitral stenosis before corrective mitral valve surgery, then to reassess the same 6 months after surgery and compare them. Patients and Methods Fifty consecutive patients with predominant severe mitral stenosis undergoing mitral valve replacement surgery were included in this prospective observational study. This study was conducted from July 2016 till January 2018 after obtaining approval from the institute's ethics committee and written consent from all the participants. All the patients were evaluated clinically and divided according to New York Heart Association (NYHA) class symptomatology. Computed spirometric pulmonary function tests (PFTs) such as forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC ratio, forced expiratory flow (FEF) 25–75%, peak expiratory flow rate (PEFR), and maximum voluntary ventilation (MVV) were performed on each patient 1 day before and 6 months after surgery. Results Fifty study patients were analyzed, mean age was 38.4 ± 10.76 years (15–56 years), and male-to-female ratio was 1:1.38 (21 males and 29 females). NYHA class symptoms improved significantly in most of our patients after surgery (p < 0.01). PFTs such as FVC, FEV1, FEV1/FVC ratio, FEF 25–75%, and MVV showed significant improvement 6 months after surgery (p < 0.01). Though PEFR also improved compared with preoperative values, it was not significant statistically (p < 0.07). Conclusion This study showed that the lung functions are impaired in patients with severe mitral stenosis and improved significantly 6 months after surgery, which does not correlate well with the betterment of NYHA class.

In-brace alterations of pulmonary functions in adolescents wearing a brace for idiopathic scoliosis

2019 ◽  
Vol 43 (4) ◽  
pp. 434-439 ◽  
Author(s):  
Gozde Yagci ◽  
Gokhan Demirkiran ◽  
Yavuz Yakut
Keyword(s):  
Idiopathic Scoliosis ◽  
Pulmonary Function ◽  
Peak Expiratory Flow ◽  
Forced Vital Capacity ◽  
Respiratory Muscle ◽  
Vital Capacity ◽  
Forced Expiratory Volume ◽  
Pulmonary Functions ◽  
Significant Difference ◽  
Expiratory Flow

Background:Despite the common use of braces to prevent curve progression in idiopathic scoliosis, their functional effects on respiratory mechanics have not been widely studied.Objective:The objective was to determine the effects of bracing on pulmonary function in idiopathic scoliosis.Methods:A total of 27 adolescents with a mean age of 14.5 ± 1.5 years and idiopathic scoliosis were included in the study. Pulmonary function evaluation included vital capacity, forced expiratory volume, forced vital capacity, maximum ventilator volume, peak expiratory flow, and respiratory muscle strengths, measured with a spirometer, and patient-reported degree of dyspnea. The tests were performed once prior to bracing and at 1 month after bracing (while the patients wore the brace).Results:Compared with the unbraced condition, vital capacity, forced expiratory volume, forced vital capacity, maximum ventilator volume, and peak expiratory flow values decreased and dyspnea increased in the braced condition. Respiratory muscle strength was under the norm in both unbraced and braced conditions, while no significant difference was found for these parameters between the two conditions.Conclusion:The spinal brace for idiopathic scoliosis tended to reduce pulmonary functions and increase dyspnea symptoms (when wearing a brace) in this study. Special attention should be paid in-brace effects on pulmonary functions in idiopathic scoliosis.Clinical relevanceBracing seems to mimic restrictive pulmonary disease, although there is no actual disease when the brace is removed. This study suggests that bracing may result in a deterioration of pulmonary function when adolescents with idiopathic scoliosis are wearing a brace.

Relative Sensitivity of Different Pulmonary Function Tests in the Evaluation of Exercise-Induced Asthma

PEDIATRICS ◽  
1975 ◽  
Vol 56 (5s) ◽  
pp. 860-867
Author(s):  
Gerd J. A. Cropp ◽  
I. J. Schmultzler
Keyword(s):  
Pulmonary Function ◽  
Airway Obstruction ◽  
Pulmonary Function Tests ◽  
Relative Sensitivity ◽  
Forced Expiratory Volume ◽  
Small Airway ◽  
Function Tests ◽  
Expiratory Flow ◽  
Exercise Induced ◽  
Small Airway Obstruction

Sixty asthmatic children were exercised on a bicycle ergometer and had pulmonary function tests performed before and repeatedly after exercise. Pulmonary function measurements included airway resistance (Raw), specific airway conductance (SGaw) functional residual capacity (FRC), peak expiratory flow rate (PEFR), maximum mid-expiratory flow (MMEF), forced expiratory volume during first second of expiration (FEV1), and forced vital capacity (FVC). At any one time during the post-exercise observation period decreases in SGaw were greater than changes in any other pulmonary function test, making SGaw the most sensitive test for the detection. of exercise-induced airway obstruction in asthmatics. Beyond five minutes after exercise PEFR and MMEF were reduced by exercise approximately equally, but somewhat less often and less markedly than SGaw. Exercise-induced reductions in FEV1 were less marked and less frequent than decreases in PEFR and MMEF, and reductions in FVC were the least severe and least often observed abnormality. Decreases in SGaw were significantly, but not linearly correlated with decreases in PEFR, MMEF, FEV1,, FVC, and FEV1/FVC. There were statistically significant linear correlations between exercise-induced increases in FRC and decreases in FVC and between increases in Raw and FRC. If we accept that increases in Raw and FRC indicate increases in large and small airway obstruction respectively, exercise-induced decreases in FVC may indirectly suggest acute hyperinflation and thus small airway obstruction. Although the positive correlation between Raw and FRC indicated that both large and small airway obstruction developed after exercise in many of our asthmatics, increases in Raw were usually greater than increases in FRC, suggesting that large airway obstruction tends to be greater than small airway obstruction in exercise-induced asthma.

Effects of Hypopressive Exercise on Posterior Back Chain Kinematics and Pulmonary Function in Professional Female Basketball Players

2021 ◽  
pp. 1-8
Author(s):  
Sonia L. Teijido ◽  
Tamara Rial Rebullido ◽  
Cinta Gómez-Tomás ◽  
Diego A. Alonso-Aubin ◽  
Iván Chulvi-Medrano
Keyword(s):  
Pulmonary Function ◽  
Peak Expiratory Flow ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Forced Expiratory Volume ◽  
Lumbar Pain ◽  
Pelvic Injury ◽  
Basketball Players ◽  
Expiratory Flow ◽  
Lower Lumbar

Context: Hypopressive exercise (HE) has been used as an alternative lumbo-pelvic injury prevention program and claimed to be a means of respiratory and flexibility improvement. However, the possible effects of HE on athletic populations and physical performance remain unclear. Objective: Examine the effects of a HE program on posterior back chain kinematics, thoracic mobility, pulmonary function, and lower lumbar pain in female basketball players over an 8-week training period. Design: Prospective (1) baseline, (2) midpoint (4 wk), and (3) after 8 weeks. Setting: Sports field. Participants: A total of 17 professional female basketball players (mean age 20.7 y, SD: 3.50; body mass index, 21.71, SD: 1.69). Intervention: Participants performed 8 HE weekly sessions of 30 minutes. Main Outcome Measures: Back chain kinematics was assessed with the sit and reach and finger to floor test, and back pain was assessed through numerical rating scale. Respiratory parameters were assessed by spirometry and through thoracic mobility. Results: The analysis of variance revealed significant differences between the 3 measurement periods for thoracic mobility (P > .01); forced expiratory volume in the first second (P < .05) while no statistical differences were found for the rest of spirometry outcomes. Significant differences were also revealed between baseline and after the intervention for the sit and reach test (P > .01), peak expiratory flow (P = .01), and forced expiratory volume in the first 25 seconds (P = .04). Also, significant differences between weeks were found in levels of lumbar pain (P = .003) and the finger to floor test (P = .002). Conclusions: These preliminary findings suggest that a HE program can improve posterior back chain and chest wall kinematics as well as lower lumbar pain levels. However, no gains seem to be observed for the majority of pulmonary variables except for peak expiratory flow and forced expiratory volume in the first seconds.

Reversive Loss of Pulmonary Function Induced by Acute Chest Syndrome: A Report from the National Acute Chest Syndrome Study Group (NACSG).

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 315-315 ◽  
Author(s):  
Lynne Neumayr ◽  
C. Morris ◽  
A. Wen ◽  
A. Earles ◽  
S. Robertson ◽  
...  
Keyword(s):  
Lung Function ◽  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Forced Expiratory Volume ◽  
Therapeutic Interventions ◽  
Acute Chest Syndrome ◽  
P Value ◽  
Lung Volumes ◽  
Expiratory Flow

Abstract Acute Chest Syndrome (ACS) remains the leading cause of death and hospitalization in patients (pts) with sickle cell disease (SCD). There is limited data on the effects of ACS on lung function. From 1993 to 1997, 30 centers participated in the NACSG and prospectively analyzed 671 episodes of ACS in 538 pts. Pulmonary function tests (PFTs) included forced expiratory volume in 1 sec (FEV1), forced vital capacity (FVC), forced expiratory flow during 25% to 75% of FVC (FEF 25–75), peak expiratory flow rate (PEF) and the ratio of FEV1/FVC. Data is reported as percent-predicted of normal values based on age and height. 128 pts (mean 16yrs, 4 to 52 yr range) had PFTs during an ACS episode (within a mean of 2.5 days of diagnosis) and then 12 weeks later. 94% of pts had abnormal lung volumes, defined as either FEV1 or FVC < 80%. Mean lung volumes during ACS and at follow-up are shown below. Table 1: Decreased Lung Volumes During ACS PFT During ACS Follow-up p-value FEV1 52% 79% <.0001 FVC 55% 83% <.0001 FEF 25–75 50% 69% <.0001 PEF 61% 83% <.0001 Pts with abnormal lung volumes (FEV1 or FVC < 80%) and considered to have an obstructive pattern if the FEV1/FVC ratio was < to 85. Obstructive patterns in pts with abnormal lung volumes and the percent of pts who responded to bronchodilators (15% improvement in either FEV1 or FVC) are shown below. Table 2: Patterns of Abnormal Lung Volumes in SCD SCD Patients During ACS Follow-up Abnormal PFTs 94% 45% Obstructive Pattern 48% 46% Respond to bronchodilators 25% 8% In summary, ACS resulted in decreased pulmonary function in 94% of pts. It is striking that 49% pts had their PFTs reduced by half (FEV1 52% and FVC 55%). In pts with abnormal PFTs, 48% had evidence of obstruction and 25% of all pts tested improved with a bronchodilator. This is the first description of reversible abnormalities of pulmonary function occurring during ACS compared to baseline. An obstructive pattern is identified in a higher percentage of pts with SCD than in the local Oakland African American population (asthma prevalance 16%). While some pts PFTs improved with time, 45% remained abnormal at 12-week follow-up. ACS results in acute and chronic worsening of lung function. Future studies of ACS may reveal common pathogenic mechanisms with asthma, and lead to improved therapeutic interventions.

COMPARISON OF PEAK EXPIRATORY FLOW TO PULMONARY FUNCTION TESTS IN PEDIATRIC PATIENTS

CHEST Journal ◽  
2006 ◽  
Vol 130 (4) ◽  
pp. 137S
Author(s):  
Edith P. Allen ◽  
Maria Martinez ◽  
Roxann Wallace ◽  
Lilia Parra-Roide ◽  
Barbara Stewart
Keyword(s):  
Pulmonary Function ◽  
Peak Expiratory Flow ◽  
Pediatric Patients ◽  
Pulmonary Function Tests ◽  
Function Tests ◽  
Expiratory Flow

scholarly journals Pulmonary functions in car air conditioner users and non-air conditioner users in tertiary care centre, South Tamilnadu, India

2019 ◽  
Vol 7 (9) ◽  
pp. 3510
Author(s):  
Hoshea Jeba Ruth S. ◽  
Lisha Vincent
Keyword(s):  
Pulmonary Function ◽  
Forced Vital Capacity ◽  
Vital Capacity ◽  
Pulmonary Function Tests ◽  
Forced Expiratory Volume ◽  
Control Group ◽  
Air Conditioner ◽  
Air Conditioners ◽  
Function Tests ◽  
Expiratory Flow

Background: Air conditioners are used extensively these days of the modern lifestyle. Inhalation of cold dry air while using Air conditioners causes bronchoconstriction due to which alteration may occur in pulmonary function. This study was aimed to compare the Pulmonary Function tests of Car AC users and non AC users. Methods: The Study included 52 employees not exposed to car air conditioner as a control (group I) and 52 employees exposed to car air conditioner  with minimum exposure of 1 hour per day for 6 months as a subject (group II). Pulmonary function tests were performed using computerised spirometer. Statistical analysis was done by unpaired t test.Results: Age, Height and weight are not statistically significant between study group and control group. Forced vital capacity, forced expiratory volume in 1 second, Ratio of Forced vital capacity and Forced expiratory volume in 1 second, Inspiratory reserve volume, Expiratory reserve volume, Maximum voluntary ventilation are decreased in car air conditioner users compared to non-users, but was not significant. Forced expiratory flow (FEF), Peak expiratory flow rate (PEFR) values shows statistically significant decreased in car air conditioner users.Conclusions: The present study shows hyper-responsive airways on exposure to cold air which leads to bronchoconstriction. The significant decrease in PEFR, FEF suggest that upper airways as well as smaller airways are affected on exposure to car AC. So, Exposure to car Air Conditioner leads to risk of developing respiratory dysfunction.

Sign in / Sign up

Export Citation Format

Share Document