scholarly journals Effectiveness of septoplasty on pulmonary function tests in symptomatic deviated nasal septum cases: a prospective study

Author(s):  
Vidya Bhargavan Panicker ◽  
B.P. Belaldavar

<p class="abstract"><strong>Background:</strong> Deviation of normal pulmonary functions leads to dysfunction of the respiratory system and this affects the functions and vitality of other related systems. Pulmonary function tests give valuable information on the state of airways, lung volumes and lung function. Hence, the present study aimed to evaluate the effectiveness of septoplasty on pulmonary function tests in symptomatic deviated nasal septum cases.</p><p class="abstract"><strong>Methods:</strong> A total of 35 patients (septoplasty: 31; septorhinoplasty: 4) with deviated nasal septum were involved in the study. Demographic data, clinical and physical examination including anterior and posterior rhinoscopy was performed. RMS Helios 702 spirometer was used to perform pre- and postoperative pulmonary function tests. Forced vital capacity (FVC), forced expiratory volume (FEV1) in 1 second, peak expiratory flow rate, and the ratio of FEV1 to FVC were the parameters measured. SPSSV. 17 was used to analyse the data.  </p><p class="abstract"><strong>Results:</strong> The deviation was most commonly seen on the left side (54%), affecting mostly the cartilaginous septum (54%). Among patients with septoplasty, the postoperative values of FVC (p&lt;0.05), FEV1 (p&lt;0.05), and peak expiratory flow (p&lt;0.05) were higher than the preoperative values and the results were statistically significant. Age, gender, laterality and duration of deviation, headache and inferior turbinate hypertrophy did not play a significant role in the enhancement of pulmonary functions after septoplasty.</p><p class="abstract"><strong>Conclusions:</strong> A favorable outcome in pulmonary function was observed in patients with deviated nasal septum after septoplasty. However, due to limited sample size, it is advisable to conduct the study in a larger sample to validate these results.</p>

2019 ◽  
Vol 43 (4) ◽  
pp. 434-439 ◽  
Author(s):  
Gozde Yagci ◽  
Gokhan Demirkiran ◽  
Yavuz Yakut

Background:Despite the common use of braces to prevent curve progression in idiopathic scoliosis, their functional effects on respiratory mechanics have not been widely studied.Objective:The objective was to determine the effects of bracing on pulmonary function in idiopathic scoliosis.Methods:A total of 27 adolescents with a mean age of 14.5 ± 1.5 years and idiopathic scoliosis were included in the study. Pulmonary function evaluation included vital capacity, forced expiratory volume, forced vital capacity, maximum ventilator volume, peak expiratory flow, and respiratory muscle strengths, measured with a spirometer, and patient-reported degree of dyspnea. The tests were performed once prior to bracing and at 1 month after bracing (while the patients wore the brace).Results:Compared with the unbraced condition, vital capacity, forced expiratory volume, forced vital capacity, maximum ventilator volume, and peak expiratory flow values decreased and dyspnea increased in the braced condition. Respiratory muscle strength was under the norm in both unbraced and braced conditions, while no significant difference was found for these parameters between the two conditions.Conclusion:The spinal brace for idiopathic scoliosis tended to reduce pulmonary functions and increase dyspnea symptoms (when wearing a brace) in this study. Special attention should be paid in-brace effects on pulmonary functions in idiopathic scoliosis.Clinical relevanceBracing seems to mimic restrictive pulmonary disease, although there is no actual disease when the brace is removed. This study suggests that bracing may result in a deterioration of pulmonary function when adolescents with idiopathic scoliosis are wearing a brace.


PEDIATRICS ◽  
1975 ◽  
Vol 56 (5s) ◽  
pp. 860-867
Author(s):  
Gerd J. A. Cropp ◽  
I. J. Schmultzler

Sixty asthmatic children were exercised on a bicycle ergometer and had pulmonary function tests performed before and repeatedly after exercise. Pulmonary function measurements included airway resistance (Raw), specific airway conductance (SGaw) functional residual capacity (FRC), peak expiratory flow rate (PEFR), maximum mid-expiratory flow (MMEF), forced expiratory volume during first second of expiration (FEV1), and forced vital capacity (FVC). At any one time during the post-exercise observation period decreases in SGaw were greater than changes in any other pulmonary function test, making SGaw the most sensitive test for the detection. of exercise-induced airway obstruction in asthmatics. Beyond five minutes after exercise PEFR and MMEF were reduced by exercise approximately equally, but somewhat less often and less markedly than SGaw. Exercise-induced reductions in FEV1 were less marked and less frequent than decreases in PEFR and MMEF, and reductions in FVC were the least severe and least often observed abnormality. Decreases in SGaw were significantly, but not linearly correlated with decreases in PEFR, MMEF, FEV1,, FVC, and FEV1/FVC. There were statistically significant linear correlations between exercise-induced increases in FRC and decreases in FVC and between increases in Raw and FRC. If we accept that increases in Raw and FRC indicate increases in large and small airway obstruction respectively, exercise-induced decreases in FVC may indirectly suggest acute hyperinflation and thus small airway obstruction. Although the positive correlation between Raw and FRC indicated that both large and small airway obstruction developed after exercise in many of our asthmatics, increases in Raw were usually greater than increases in FRC, suggesting that large airway obstruction tends to be greater than small airway obstruction in exercise-induced asthma.


2019 ◽  
Vol 6 (2) ◽  
pp. 306
Author(s):  
Manaswita Gadiparthi ◽  
Nalini Bhaskaranand ◽  
Pushpa G. Kini ◽  
Shrikiran Hebbar ◽  
Suneel C. Mundkur

Background: Extensive studies are conducted on heart, liver and endocrine abnormalities in thalassemia owing to their direct effect on survival, however, lung dysfunction has never been focused upon and is one of the least understood complications in β thalassemia. There’s a vacuum for data on pulmonary function tests in β thalassemia major in literature from India. Authors aimed to study pulmonary function and type of abnormality in cases with β thalassemia major above the age of 8yrs and to correlate the result with age and serum ferritin levels.Methods: Demographic data, hemoglobin value, serum ferritin levels, chelation details and transfusion requirement were analyzed. Spirometry was performed using COSMED pulmonary function test (PFT).Results: Among the 34 subjects studied, 21 were boys, and 13 were girls. Mean serum ferritin levels of the group was 3610.82±2679.51ng/mL and did not show a significant correlation with age, years of transfusion, and years of chelation. Forced vital capacity (FVC), forced expiratory volume in 1st second (FEV1) % values were lower in boys when compared to girls. PFT showed a restrictive pattern in the study group (FEV1/FVC=>0.7) with significant involvement in 73.5% of cases (FEV1<80%). A statistically significant negative correlation was observed between age and FEV1% (r=-0.577, p=<0.01) highlighting the importance of duration of iron overload. However, there was no significant linear correlation between restrictive lung disease and serum ferritin level (r=-0.06, p=0.75).Conclusions: Restrictive pattern was the most common abnormality, and it did not correlate with serum ferritin. Pulmonary function monitoring would help in identifying children with significant morbidity and help in initiating an early intervention to improve the quality of life.


CHEST Journal ◽  
2006 ◽  
Vol 130 (4) ◽  
pp. 137S
Author(s):  
Edith P. Allen ◽  
Maria Martinez ◽  
Roxann Wallace ◽  
Lilia Parra-Roide ◽  
Barbara Stewart

Author(s):  
Hoshea Jeba Ruth S. ◽  
Lisha Vincent

Background: Air conditioners are used extensively these days of the modern lifestyle. Inhalation of cold dry air while using Air conditioners causes bronchoconstriction due to which alteration may occur in pulmonary function. This study was aimed to compare the Pulmonary Function tests of Car AC users and non AC users. Methods: The Study included 52 employees not exposed to car air conditioner as a control (group I) and 52 employees exposed to car air conditioner  with minimum exposure of 1 hour per day for 6 months as a subject (group II). Pulmonary function tests were performed using computerised spirometer. Statistical analysis was done by unpaired t test.Results: Age, Height and weight are not statistically significant between study group and control group. Forced vital capacity, forced expiratory volume in 1 second, Ratio of Forced vital capacity and Forced expiratory volume in 1 second, Inspiratory reserve volume, Expiratory reserve volume, Maximum voluntary ventilation are decreased in car air conditioner users compared to non-users, but was not significant. Forced expiratory flow (FEF), Peak expiratory flow rate (PEFR) values shows statistically significant decreased in car air conditioner users.Conclusions: The present study shows hyper-responsive airways on exposure to cold air which leads to bronchoconstriction. The significant decrease in PEFR, FEF suggest that upper airways as well as smaller airways are affected on exposure to car AC. So, Exposure to car Air Conditioner leads to risk of developing respiratory dysfunction.


2020 ◽  
Author(s):  
Khadidja Chelabi ◽  
Fabio Balli ◽  
Myriam Bransi ◽  
Yannick Gervais ◽  
Clement Marthe ◽  
...  

BACKGROUND International asthma guidelines recommend the monitoring of peak expiratory flow (PEF) as part of asthma self-management in children and adolescents who poorly perceive airflow obstruction, those with a history of severe exacerbations, or have difficult to control asthma. Measured with a peak flow meter, PEF represents a person’s maximum speed of expiration and helps individuals to follow their disease evolution and ultimately to prevent asthma exacerbations. However, adherence to this practice is poor, particularly in the pediatric population. To address this, we developed an interactive serious game consisting of a portable game controller that can transduce a signal from the breath to generate a PEF value when coupled with a tablet-based game. OBJECTIVE We evaluated the concordance between PEF values obtained with the game controller (PEFGC) and various measures derived from conventional pulmonary function tests (i.e spirometry) and we synthesized the participants’ feedback. METHODS In this cross-sectional multicenter study, 158 children aged 8-15 years old with a diagnosis or suspicion of asthma performed spirometry and played with the game in one of 2 hospital university centers. We evaluated the correlation between PEFGC and spirometry measurements, including PEF values (PEFspiro), forced expiratory volume in 1 second (FEV1) and forced expiratory volume at 25-75% of pulmonary volume (FEF25-75), using Spearman correlation. A Bland-Altman plot was generated for comparison of PEFGC against PEFspiro. A post-game user feedback questionnaire was administered and analyzed. RESULTS The participants had a mean age (SD) of 10.9 2.5) years, 44% were female, and 88.6% Caucasians. On average, their pulmonary function were normal, including FEV1, PEF and FEV1/FVC. The PEFGC was reproducible in 96.2% of participants according to standardized criteria. The PEFGC presented a good correlation with PEFspiro (r=0.83, p<0.001), with FEV1 (r=0.74, p<0.001) and with FEF25-75 (r=0.65, p<0.001). The PEFGC presented an expected mean bias of -36.4 L/min as compared to PEFspiro. The participants’ feedback was strongly positive with 78.4% reporting they would use the game if they had it at home. CONCLUSIONS The game controller developed is an interactive tool appreciated by children with asthma and whose values are reproducible with a good correlation when compared to conventional spirometry. Future studies are necessary to evaluate the clinical impact this novel tool might have on asthma management and its potential use in an out-of-hospital setting. CLINICALTRIAL


Rheumatology ◽  
2019 ◽  
Vol 59 (8) ◽  
pp. 2024-2029 ◽  
Author(s):  
Yukai Wang ◽  
Shaoqi Chen ◽  
Jianqun Lin ◽  
Xuezhen Xie ◽  
Shijian Hu ◽  
...  

Abstract Objective Idiopathic inflammatory myositis-associated interstitial lung disease (IIM-ILD) significantly increases morbidity and mortality. Lung ultrasound B-lines and Krebs von den Lungen-6 (KL-6) are identified as new sonographic and serum markers of ILD, respectively. The aim of our work was to assess the role of B-lines and KL-6 as markers of the severity of IIM-ILD. For this purpose, the correlation among B-lines score, serum KL-6 levels, high-resolution CT (HRCT) score, and pulmonary function tests were investigated in IIM-ILD patients. Methods Thirty-eight patients with IIM-ILD underwent chest HRCT scans, lung ultrasound and pulmonary function tests (independently performed within 1 week) examination. To assess severity and extent of ILD at HRCT, the Warrick score was used. The B-lines score denoting the extension of ILD was calculated by summing the number of B-lines on a total of 50 scanning sites. Serum KL-6 levels (U/ml) was measured by chemiluminescent enzyme immunoassay. Results A significant correlation was found between the B-lines score and serum KL-6 levels (r = 0.43, P &lt; 0.01), and between the Warrick score and serum KL-6 levels (r = 0.45, P &lt; 0.01). A positive correlation between B-lines score and the Warrick score (r = 0.87, P &lt; 0.0001) was also confirmed. Both B-lines score and KL-6 levels inversely correlated to diffusion capacity for carbon monoxide (r = −0.77, P &lt; 0.0001 and r = −0.42, P &lt; 0.05, respectively) and total lung capacity (r = −0.73, P &lt; 0.0001 and r = −0.36, P &lt; 0.05, respectively). Moreover, B-lines correlated inversely with forced vital capacity (r = −0.73, P &lt; 0.0001), forced expiratory volume in 1 s (r = −0.69, P &lt; 0.0001). Conclusion B-lines score and serum KL-6 levels correlate with HRCT findings and pulmonary function tests, supporting their use as measures of IIM-ILD severity.


2021 ◽  
Vol 6 (3) ◽  
pp. 236-243
Author(s):  
Krupa Pareshbhai Patel ◽  
Anjali Bhise

Background: Spirometry is a universal, simple, and non-invasive pulmonary function test. Spirometry, along with calculation of the forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC), is helpful for diagnosing obstructive or restrictive lung disease. Postoperative Pulmonary Complications are defined as unintended pulmonary abnormalities that occur as a result of surgery which cause identifiable dysfunction. Purpose: To find the evidence showing the importance of pre-operative PFT to predict risk of pulmonary complications after abdominal surgery Methodology: The study was conducted according to Preferred Reporting Items for systematic reviews and meta-analysis guidelines. Evidences selected since year 2002- 2020 from PubMed, Google Scholar, Physiotherapy Evidence Database (PEDro), ResearchGate and ScienceDirect. Key words used were: Pulmonary Function Tests, Post-Operative Pulmonary Complications, and Abdominal Surgery. Analysis was done using 2 scales: Centre for Evidence-Based Medicine Levels of Evidence Scale. Total 12 articles were found. Among them 10 were selected. Results: 5 articles showed that preoperative PFT is important in prediction of PPCs while the other half concluded that routine preoperative spirometry is not necessary before non-thoracic surgeries. Conclusion: Based on evidences, in the nutshell it is reviewed that there is controversy regarding the value of preoperative pulmonary functions test in non-thoracic surgeries. Keywords: Pulmonary Function Tests, Post-Operative Pulmonary Complications, and Abdominal Surgery


2017 ◽  
Vol 6 (1) ◽  
pp. 21
Author(s):  
N B Mahotra ◽  
T M Amatya ◽  
B SJB Rana ◽  
D Banstola

<p> Due to regular exercises, athletes tend to have an increase in pulmonary functions when compared to non exercising individuals, especially when the exercise is strenuous. Intensity and severity of sports engaged in by the athletes determines the extent of strengthening of the inspiratory muscles with a resultant increase in the lung volumes and capacities. Pulmonary parameters like tidal volume and forced vital capacity are significantly higher in athletes than in non athletes. A cross sectional comparative study was carried out in national sports council, Tribhuvan army club and institute of medicine, Kathmandu, Nepal. The athletes were footballers from Tribhuvan army club and sprinters from national sports council. The non-athletes were medical students from the institute of medicine, Kathmandu. Data were collected after performing spirometry and mean values were compared between athletes and non-athletes. Pulmonary functions were assessed based on forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1) and peak expiratory flow rate (PEFR) expressed as percent predicted for the age, sex, height, weight and race. Spirometry was performed in 169 subjects, out of which 84 were athletes and 85 were non-athletes. Athletes had a significantly superior FVC (P =0.00) compared to non-athletes. FEV1 was also recorded significantly higher in athletes than in non-athletes (P=0.023). Athletes have better pulmonary function tests than non-athletes because exercise in athletes strengthens the muscles of respiration. </p>


2018 ◽  
Vol 02 (02) ◽  
pp. 079-083
Author(s):  
Manoj Kumar Sahu ◽  
Mayank Yadav ◽  
Milind Padmakar Hote ◽  
Sarvesh Pal Singh ◽  
Shiv Kumar Choudhary

Abstract Objective This study was undertaken to assess the pulmonary functions in the patients with predominant severe mitral stenosis before corrective mitral valve surgery, then to reassess the same 6 months after surgery and compare them. Patients and Methods Fifty consecutive patients with predominant severe mitral stenosis undergoing mitral valve replacement surgery were included in this prospective observational study. This study was conducted from July 2016 till January 2018 after obtaining approval from the institute's ethics committee and written consent from all the participants. All the patients were evaluated clinically and divided according to New York Heart Association (NYHA) class symptomatology. Computed spirometric pulmonary function tests (PFTs) such as forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC ratio, forced expiratory flow (FEF) 25–75%, peak expiratory flow rate (PEFR), and maximum voluntary ventilation (MVV) were performed on each patient 1 day before and 6 months after surgery. Results Fifty study patients were analyzed, mean age was 38.4 ± 10.76 years (15–56 years), and male-to-female ratio was 1:1.38 (21 males and 29 females). NYHA class symptoms improved significantly in most of our patients after surgery (p < 0.01). PFTs such as FVC, FEV1, FEV1/FVC ratio, FEF 25–75%, and MVV showed significant improvement 6 months after surgery (p < 0.01). Though PEFR also improved compared with preoperative values, it was not significant statistically (p < 0.07). Conclusion This study showed that the lung functions are impaired in patients with severe mitral stenosis and improved significantly 6 months after surgery, which does not correlate well with the betterment of NYHA class.


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