scholarly journals Post-viral fatigue syndrome in children: does it need to be treated?

2021 ◽  
Vol 16 (6) ◽  
pp. 425-434
Author(s):  
I.L. Vysochyna ◽  
V.V. Kramarchuk ◽  
T.O. Yashkina
Keyword(s):  
Pediatric Population ◽  
Pharmacological Action ◽  
The Body ◽  
Biologically Active ◽  
Term Therapy ◽  
Attention Disorders ◽  
Fatigue Syndrome ◽  
Regulatory Systems ◽  
Complete Restoration ◽  
Long Term Therapy

Acute respiratory viral diseases continue to dominate among the causes for seeking medical help. In the pediatric population, about 60 % of cases have a recurrent course, which in turn often leads to the development of post-viral asthenic syndrome. In such children, one can find rapid fatigability, attention disorders and inability to concentrate, impaired information processing, emotional lability, and sleep disorders. All this disrupts the usual way of life of both the child and his relatives that undoubtedly requires the treatment of this condition and complete restoration of the state of the body after episodes of acute respiratory diseases. Phytotherapy has found its place in the management of children with post-viral asthenia due to the polyvalence of the pharmacological action, proven efficiency, safety of long-term therapy with phytopreparations and economic attractiveness for the majority of the population. In modern realities, phytotherapy is used as a reductive therapy, which makes up for the lack of products of intermediate metabolism in the body; as detoxification therapy that provides adsorption or chemical binding of exo- and endotoxins, increasing the body’s resistance to them and stimulating the excretory systems. It is important to use the neurotropic, immunotropic, hormone-like action of biologically active substances of plants; natural compounds, actively modifying the functions of regulatory systems, have prospects in the treatment of complex diseases. Analysis of the search databases PubMed, Web of Science, Scopus, Google Scholar, RSCI, Index Copernicus, BMJ, MEDLINE on the possibility of use, efficacy and safety of phytocomponents of Alleva in children of different ages with symptoms of post-viral asthenia allowed to ensure the application of this drug to control manifestations of asthenic syndrome. The article analyzes the options for correcting childhood asthenia with dry concentrates of linden flowers, lemon balm, chamomile, extracts of passionflower, hop, orange tree and lavender.

scholarly journals A Randomized Open Clinical Study of the Atherosclerosis Treatment Information Video Effect on Adherence to Long-Term Therapy in Patients with Cardiovascular Diseases

2021 ◽  
Vol 17 (5) ◽  
pp. 683-687
Author(s):  
Yu. V. Bulaeva ◽  
E. A. Naumova ◽  
O. N. Semenova ◽  
T. V. Kanaeva ◽  
K. A. Popov ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Patient Adherence ◽  
Intervention Group ◽  
Cardiovascular Complications ◽  
The Body ◽  
Term Therapy ◽  
Control Group ◽  
Treatment Information ◽  
Long Term Therapy

Aim. Study the effect of a study video, which was created by researchers and devoted to the atherosclerosis development and the effect of statin therapy on atherosclerotic plaque, on adherence to long-term therapy in patients with high or very high risk of cardiovascular complications.Material and methods. 120 patients admitted to hospital with cardiovascular diseases were included in the study. Patients were randomized into 2 groups: in the main group (n=60), the information video edited by the researchers was shown to patients on the eve of discharge, in addition to a printed brochure on lifestyle and diet modification, and in the control group (n=60), patients were given only a standard brochure. The motivating video shows the damage to the cardiovascular system by the atherosclerotic process and the beneficial effect on the body of constant intake of statins. After 1 and 3 months after discharge from the hospital, telephone calls were made, after which the patients had to visit the center for an objective examination by a researcher and control of laboratory parameters. After 1 month, 110 patients visited the center, after 3 months, 98 respondents visited the center.Results. The group with the information video demonstration noted more frequent adherence to medical recommendations compared to the control: after 1 month, 52 (96%) patients continued treatment versus 48 (86%) patients, 3 months after discharge 48 (96%) patients continued treatment versus 38 (79%) patients (p<0.05). After 1 month, 38 (70%) patients in the intervention group continued taking statins versus 29 (43%) respondents in the control group (p<0.05), 3 months after discharge, 40 (80%) patients in the intervention group continued to take statins versus 33 (69%) control patients (p<0.09).Conclusion. Demonstration of a motivating video about the effect of statins on the atherosclerosis course increases patient adherence to medicinal therapy, including adherence to statins.

Atypical use of PICC in Infants and Small Children: A Unicentric Experience

2017 ◽  
Vol 18 (6) ◽  
pp. 535-539 ◽  
Author(s):  
Filippo Bernasconi ◽  
Clelia Zanaboni ◽  
Andrea Dato ◽  
Andrea Dolcino ◽  
Michela Bevilacqua ◽  
...  
Keyword(s):  
Vascular Access ◽  
Pediatric Population ◽  
Conventional Technique ◽  
Term Therapy ◽  
Puncture Site ◽  
Vascular Access Devices ◽  
Small Children ◽  
Long Term Therapy ◽  
Central Catheters

Introduction The peripherally inserted central catheters (PICCs) are vascular access devices (VAD) that are increasingly being used in the pediatric population. If a small vein caliber prevents positioning the catheter in the arm, the following step is to position the same catheter in the supraclavicular area, which can be defined as an off-label use or “atypical” approach, first described by Pittiruti. Materials and methods We retrospectively reviewed PICC positioning with puncture-site in the supra-clavicular area (“atypical” PICC insertion) and then tunneled on the chest. Results Nineteen atypical PICCs were positioned in 18 patients. The median age of patients at the day of implant was 14 months (IQR 3-27 months), and weight 7.5 kg (IQR 4-12 kg). Within this population, 74% of cases scheduled for a typical PICC insertion presented vein caliber too small for this procedure. For this reason, the typical PICC insertion was changed in favor of an atypical PICC procedure. Atypical PICCs were successfully used in 100% of cases without immediate complications. Conclusions Atypical PICC positioning is a safe and useful alternative to the conventional technique when there is need for a central vascular access device (CVAD) for mid- or long-term therapy.

scholarly journals Ayurveda and Modern Perspective on Rajonivrittiw.s.r. to Menopause: Review Based on Literary Study

2021 ◽  
Vol 04 (11) ◽  
pp. 109-113
Author(s):  
Monika Kumari ◽  
Mahesh Dixit ◽  
Narendra Kumar Meena
Keyword(s):  
Hormone Replacement ◽  
Cost Effective ◽  
Modern Medicine ◽  
The Body ◽  
Term Therapy ◽  
Cost Effective Treatment ◽  
Long Term Therapy ◽  
Modern Perspective

Menopause, a phenomenon unique to women, is the ending of a woman’s monthly menstrual period and ovulation. It, alongside, several other changes in the bodyand mind, brought in due to a decline in the amount of the hormones estrogen and progesterone being produced by the body. Menopause is, occasionally, viewed as an end to youth and sexuality, making it a socially unacceptable occurrence. Menopause, though,one of the important physical and mental milestones in a woman’s life, many women lack information about what is taking place and what are their options. There comes the role of Ayurveda , in Ayurveda literature there is no detailed description of Rajonivrittior menopause except the age of Rajonivrittiis given as 50 years. Ayurveda involves a holistic physiological system based on balance, with its cardinal doctrine of human physiology being constituted by “vata”, “pitta” and “kapha”. In modern medicine the only treatment for these symptoms is Hormone replacement therapy (HRT), which is not a long-term therapy to be given as it has side effects on the overall health of the women. In Ayurveda Dhatu kshaya can be treated with Rasayanatherapy and other symptoms of hypo-estrogenic conditions can be treated with Phytoestrogens. So, Ayurveda gives a non-hormonal and cost-effective treatment for Rajonivrittior Menopause.

scholarly journals Apoptosis a role in the development of type 1 diabetes

2000 ◽  
Vol 46 (2) ◽  
pp. 8-13
Author(s):  
T. V. Mokhort ◽  
S. B. Melnov ◽  
V. A. Goranov
Keyword(s):  
Direct Contact ◽  
Insulin Dependent Diabetes Mellitus ◽  
The Body ◽  
Biologically Active ◽  
Dependent Diabetes Mellitus ◽  
Regulatory Systems ◽  
Insulin Dependent ◽  
P Cells ◽  
Active Substances

In recent decades, the attention of biologists and doctors of various specialties has been attracted by the phenomenon of apoptosis a genetically programmed process of death and utilization of committed cells with the participation of biochemical reactions controlled by the whole organism [6 |. This process starts as a result of the interaction of the regulatory systems of the body and (or) direct contact with biologically active substances that directly or indirectly affect the functional state of the cells [2]. Obviously, apoptosis is of great importance for the processes that ensure the physiological renewal of tissues in the body, and for pathological processes, in particular autoimmune, accompanied by cell death. At present, there is sufficient reason to assert that insulin-dependent diabetes mellitus (IDDM) occurs as a result of the death of P-cells (CD) as a result of the cytotoxic effect of immunological agents and (or) certain chemicals [1] that proceeds with the participation of apoptosis.

Efficacy of Crisis Intervention

Crisis ◽  
1999 ◽  
Vol 20 (2) ◽  
pp. 78-85 ◽  
Author(s):  
Thomas Reisch ◽  
Petra Schlatter ◽  
Wolfgang Tschacher
Keyword(s):  
Crisis Intervention ◽  
Intervention Program ◽  
Suicide Ideation ◽  
Indirect Evidence ◽  
Well Being ◽  
Term Therapy ◽  
Contributing Factors ◽  
Step Therapy ◽  
Long Term Therapy ◽  
The Impact

This study assesses the efficacy of the treatment approach implemented in the Bern Crisis Intervention Program, where particular emphasis is placed on the remediation of suicide ideation and suicidal behavior, and depression, fear, and phobia are generally considered to be contributing factors. Four questionnaires addressing psychopathology, emotional well-being, social anxiety, and personality were administered prior to and after the treatment of 51 patients over a period of 2 to 3 weeks. The reduction of symptoms contributing to suicidal ideation and behavior was interpreted as indirect evidence of an antisuicidal effect of the program. Significant improvements were found in the psychopathology ratings, with depression and anxiety showing the largest reductions. The impact on personality and social phobia, however, was only moderate, and on average patients still exhibited symptoms after attending the program. This residual symptomatology points to the necessity of introducing a two-step therapy approach of intensive intervention targeted at the precipitating causes of the crisis, augmented by long-term therapy to treat underlying problems.

Antithrombotic Therapy for DVT/PE

1997 ◽  
Vol 17 (03) ◽  
pp. 161-162
Author(s):  
Thomas Hyers
Keyword(s):  
Molecular Weight ◽  
Low Molecular Weight Heparin ◽  
Oral Anticoagulants ◽  
Cost Effective ◽  
Therapeutic Agents ◽  
Great Promise ◽  
Term Therapy ◽  
Low Molecular Weight ◽  
Long Term Therapy

SummaryProblems with unfractionated heparin as an antithrombotic have led to the development of new therapeutic agents. Of these, low molecular weight heparin shows great promise and has led to out-patient therapy of DVT/PE in selected patients. Oral anticoagulants remain the choice for long-term therapy. More cost-effective ways to give oral anticoagulants are needed.

Office-based post-marketing surveillance study on the influence of long term therapy with aripiprazole in patients with schizophrenia

2007 ◽  
Vol 40 (05) ◽  
Author(s):  
M Kungel ◽  
A Engelhardt ◽  
T Spevakné-Göröcs ◽  
M Ebrecht ◽  
C Werner ◽  
...  
Keyword(s):  
Surveillance Study ◽  
Term Therapy ◽  
Post Marketing Surveillance ◽  
Post Marketing ◽  
Long Term Therapy

Neutral Lipids of Oats Fruit (Avena Sativa L.)

2020 ◽  
Vol 9 (4) ◽  
pp. 40-43
Author(s):  
N. K. Yuldasheva ◽  
S. D. Gusakova ◽  
D. Kh. Nurullaeva ◽  
N. T. Farmanova ◽  
R. P. Zakirova ◽  
...  
Keyword(s):  
Avena Sativa ◽  
Neutral Lipids ◽  
The Body ◽  
Biologically Active ◽  
Absorption Bands ◽  
Vital Functions ◽  
The Republic ◽  
Living Organisms ◽  
Main Components ◽  
Active Substances

Introduction. Lipids are a widespread group of biologically active substances in nature, making up the bulk of the organic substances of all living organisms. They accumulate in plants in seeds, as well as in fruits and perform a number of vital functions: they are the main components of cell membranes and the energy reserve for the body.Aim. Study of neutral lipids of sown oats (Avena sativa L.).Materials and methods. The objects of the study were fruits (grains) of oats of the sown variety "Tashkent 1," harvested in the Republic of Uzbekistan. Results and discussions. Neutral lipids of oat grains have been found to contain 13 fatty acids with a predominance of the sum of oleic, linolenic and linoleic acids. The total degree of unsaturation was almost 78%. Absorption bands characteristic of these substances were observed in the IR spectrum of MEGC.Conclusion. According to the results of the NL analysis, oat grains consisted of triacylglycerides and free LCDs, which were accompanied by hydrocarbons, phytosterols, triterpenoids and tocopherols.

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