scholarly journals DAPSONE INDUCED DRESS: A CASE REPORT

2017 ◽  
Vol 10 (5) ◽  
pp. 4 ◽  
Author(s):  
Balaji Ommurugan ◽  
Amita Priya ◽  
Manu Matthew George ◽  
Meena Kuamri Kamalkishore ◽  
Mohan Babu Vittalrao Amberkar
Keyword(s):  
Rare Case ◽  
Liver Toxicity ◽  
Tertiary Care Hospital ◽  
Drug Effect ◽  
Tertiary Care ◽  
Organ Damage ◽  
Multiple Organ ◽  
Care Hospital ◽  
First Line ◽  
Systemic Symptoms

Drug reaction with eosinophilia and systemic symptoms. is a very dangerous adverse drug effect causing rashes, eosinophilia, and multiple organ damage. Many drugs are implicated in causing DRESS with most common ones being antimicrobials and antiepileptics. Dapsone used in the treatment of Hansen’s disease as a first-line agent is known for causing many side effects ranging from nausea, vomiting, insomnia, anaphylaxis, hypersensitivity reactions, rashes, muscle weakness, abdominal pain, and so on. Hence, we report a rare case of dapsone-induced DRESS in a tertiary care hospital in South India.Keywords: Dapsone, Adverse effect, Liver toxicity, Rashes, Eosinophilia.

scholarly journals A rare case of subcutaneous dirofilariasis from a tertiary care hospital in Western Maharashtra

2021 ◽  
Vol 14 (1) ◽  
pp. 80
Author(s):  
Shahzad Mirza ◽  
NageswariR Gandham ◽  
NikunjaK Das ◽  
RabindraN Misra
Keyword(s):  
Rare Case ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital

scholarly journals Reducing the Risk of Severe Complications among Patients withClostridium difficileInfection

2011 ◽  
Vol 25 (7) ◽  
pp. 368-372 ◽  
Author(s):  
Kamran Manek ◽  
Victoria Williams ◽  
Sandra Callery ◽  
Nick Daneman
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Multivariable Analysis ◽  
Rapid Onset ◽  
Complication Rates ◽  
Care Hospital ◽  
Clinical Factors ◽  
Blood Cell Count ◽  
First Line ◽  
Repeat Infection

BACKGROUND: The incidence and severity ofClostridium difficileinfections are increasing, and there is a need to optimize the prevention of complicated disease.OBJECTIVE: To identify modifiable processes of care associated with an altered risk ofC difficilecomplications.METHODS: A retrospective cohort study (with prospective case ascertainment) of allC difficileinfections during 2007/2008 at a tertiary care hospital was conducted.RESULTS: Severe complications were frequent (occurring in 97 of 365 [27%]C difficileepisodes), with rapid onset (median three days postdiagnosis). On multivariable analysis, nonmodifiable predictors of complications included repeat infection (OR 2.67), confusion (OR 2.01), hypotension (OR 0.97 per increased mmHg) and elevated white blood cell count (OR 1.04 per 109cells/L). Protection from complications was associated with initial use of vancomycin (OR 0.24); harm was associated with ongoing use of exacerbating antibiotics (OR 3.02).CONCLUSION:C difficileinfections often occur early in the disease course and are associated with high complication rates. Clinical factors that predicted a higher risk of complications included confusion, hypotension and leukocytosis. The most effective ways to improve outcomes for patients withC difficilecolitis are consideration of vancomycin as first-line treatment for moderate to severe cases, and the avoidance of unnecessary antibiotics.

scholarly journals A Rare Case Report of Splenic Abscess Caused by Burkholderia pseudomallei Progressing to Disseminated Melioidosis

2021 ◽  
Vol 10 (11) ◽  
pp. 200-206
Author(s):  
Lakshmi Shanmugam Priyadarshi Ketan ◽  
Stanley Pheba Monika Sivaradjy ◽  
S. Balamurugan Elamurugan Thirthar Palanivelu ◽  
Sastry Apurba Sankar
Keyword(s):  
Burkholderia Pseudomallei ◽  
Rare Case ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Splenic Abscess ◽  
Care Hospital ◽  
Rare Case Report ◽  
Threatening Condition ◽  
Life Threatening ◽  
Upper Abdomen

Splenic abcess is a rare but potentially life threatening condition which can be less frequently caused by gram negative saprophytes, Burkholderia pseudomallei. Because of the challenges faced in the identification of this organism, it is often under diagnosed or misdiagnosed. Here, we report a case of splenic abcess eventually leading to disseminated melioidosis caused by Burkholderia pseudomallei in a 40 year old diabetic male from a tertiary-care hospital in southern India, who presented with fever and pain over left upper abdomen.

scholarly journals Subarachnoid haemorrhage from Spinal Dural Arteriovenous Fistula in a child

2018 ◽  
Author(s):  
Narindra Ramnarine ◽  
Patrick Knight ◽  
Devindra Ramnarine
Keyword(s):  
Rare Case ◽  
Dural Arteriovenous Fistula ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Age Groups ◽  
Cerebral Aneurysms ◽  
Paediatric Population ◽  
Care Hospital ◽  
Spinal Dural Arteriovenous Fistula ◽  
Common Cause

SAH in the paediatric population is an uncommon entity accounting for 1-2% of SAH in all age groups & only 18% of ICH in the paediatric population. Trauma is the most common cause of isolated SAH in the paeditric population, with ruptured intracerebral aneurysms although still rare, being the most common cause of spontaneous SAH in children. AVMs are uncommon source of spontaneous SAH. Although they are 10 times more common than cerebral aneurysms in the paediatric population, they rarely present with isolated SAH. This report aims to present such a rare case presented to a tertiary care hospital in Trinidad.

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